• Food Science and Biotechnology
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• 제15권3호
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• pp.329-338
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• 2006

The study of health promoting and disease preventing compounds in food or by themselves, so called nutraceuticals or functional foods, has become a major field of research in food science. Natural flavor compounds are usually present in food, essential oils, spices, and herbs. These compounds can produce aroma, not only by themselves, but also in combination with other compounds. Today, however, greater interest is being paid to the health promoting properties of natural flavor substances rather than their flavoring properties. In fact, a number of naturally occurring flavor compounds that possess health promoting and disease preventing properties have been extensively studied and identified. The beneficial properties of natural volatile flavor compounds as well as non-volatile substances in spices and herbs discussed in this review include antioxidant, anticarcinogenic, anti-inflammatory, and immune enhancing activities.

• 한국응용과학기술학회지
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• 제33권1호
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• pp.155-167
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• 2016

Surface-active substances in defatted rapeseed cake were obtained using a supercritical fluid extraction method. Then, it was purified by removing sinapine in the extract through a series of steps using a mixed solvent: diethyl ether and ethyl acetate (1:1, v/v). Emulsifying properties of purified surface-active substances were investigated, including fat globule size, zeta potentials and creaming stability and its antioxidant activity in emulsion systems were also studied by peroxide value and $^1H$-NMR spectrum. It was found that fat globules in emulsions with purified surface-active substances were much smaller than ones with the unpurified. In addition, as pH of the emulsion lowered and with increasing NaCl concentration in the emulsion, they were observed to increase, which led to worse creaming stability. These properties were reflected in changes of zeta potentials of emulsions. The oxidative stability was better in emulsions with purified surface-active substances than ones with Tween 20 or commercial lecithin, possibly resulted from the existence of sinapic acid in the extract. It was concluded that purified surface-active substances from defatted rapeseed cake could be simultaneously used as emulsifier and antioxidant agent in emulsion system.

• Environmental Analysis Health and Toxicology
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• 제30권sup호
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• pp.4.1-4.7
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• 2015

Objectives Approximately 2000 phase-in substances are subject to registration according to the Act on the Registration and Evaluation, etc. of Chemical Substances (K-REACH), and the expected testing cost is 2.06 trillion Korean won assuming all the test data required for registration are acquired. The extent to which these enormous test costs can be reduced depends on the availability of existing data that can be used to meet the requirements of the K-REACH we examined the current availability of test data that can be used for chemical substance registration. Methods We analyzed the possibility of utilizing the existing test data obtained from 16 reference databases for 369 of 518 kinds of phase-in substances subject to registration that were reported in last October 2014. Results The physical and chemical properties were available for 57.1% of substances, whereas data regarding human hazards and environmental hazards were available at considerably lower rates, 8.5% and 11.8%, respectively. Conclusions Physical and chemical properties were available for a fairly high proportion, whereas human hazards and environmental hazards were reported for considerably fewer substances.

• Journal of Microbiology and Biotechnology
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• 제22권12호
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• pp.1597-1604
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• 2012

Genus Bacillus is a spore-forming bacterium that has unique properties in cell differentiation, allowing the forming of spores in stress conditions and activated in the vegetative cell, with suitable environments occurring during the life cycle acting as a trigger. Their habitat is mainly in soil; thus, many species of Bacillus are associated with plants as well as rhizosphere bacteria and endophytic bacteria. Signal transduction is the principal mechanism of interactions, both within the cell community and with the external environment, which provides the subsequent functions or properties for the cell. The antimicrobial compounds of Bacillus sp. are potentially useful products, which have been used in agriculture for the inhibition of phytopathogens, for the stimulation of plant growth, and in the food industry as probiotics. There are two systems for the synthesis of these substances: nonribosomal synthesis of cyclic lipopeptides (NRPS) and polyketides (PKS). For each group, the structures, properties, and genes of the main products are described. The different compounds described and the way in which they co-exist exhibit the relationship of Bacillus substances to plants, humans, and animals.

• 한국전기전자재료학회논문지
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• 제25권9호
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• pp.711-716
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• 2012

Based on both organic synthesis and theoretical calculations on the effects of molecular orbital energy levels of amines on the fluorescence properties of the fluorophore, fluorescent "turn-on" chemosensors detecting hazardous substances, including aldehyde chemicals and $Hg^{2+}$ ion, were developed.

• 한국산업보건학회지
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• 제32권3호
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• pp.209-220
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• 2022

Objectives: This study was performed to suggest how to re-establish criterion for toxic substances under the Chemical Control Act (CCA) in South Korea by comparing the GHS (Globally Harmonized System of Classification and Labeling of Chemicals) score and toxic properties. Methods: Toxic substances were classified into seven groups (Acute toxicity (1A), Chronic toxicity (2C), Environmental hazards (3E), Acute toxicity & chronic toxicity (4AC), Chronic toxicity & environmental hazards (5CE), Acute toxicity & environmental hazards (6AE), and Acute toxicity & chronic toxicity & environmental hazards (7ACE)) according to their toxic properties. The GHS score was calculated to sum up five toxicity indicators (health acute toxicity, health repeated toxicity, carcinogenicity, health other chronic toxicity and environmental hazards). Results: The GHS score of 7ACE was higher by 7 times that of 1A. 1A is the only group which has lower than the total GHS score. The highest score was 47, for sodium chromate (CAS no. 7775-11-3), which belongs to group 7ACE. This is classified as acute toxicity, carcinogenicity, germ cell mutagenicity, reproductive toxicity, and acute and chronic environmental hazard. On the other hand, the lowest score was 2.75, which was assigned to 177 chemicals belonging to group 1A. When the health acute toxicity indicator was omitted from the toxic criterion, toxic substances could be divided into the sub-groups 'human chronic hazards group' (HCG) and 'environmental hazards group' (EG) according to their GHS score and properties. Conclusions: The proposed criterion for toxic substances is to establish sub-groups defined as HCG and EG for separate control and that the 1A group be moved to substances requiring preparation for accidents under the CCA.

• 한국토양비료학회지
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• 제6권1호
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• pp.67-73
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• 1973

Soil humic substances are defined as a humified part of the soil organic matters and regarded to play beneficial roles for colloid chemical properties and the fertility of the soils. This paper is referred to review the present trend of the studies on the forming processes of humic substances and on the effect on plant metabolism by some organic compounds that are directly absorbed by plants. It is generally considered that the humic substances are formed organic matters in soil or plant materials through numerous organic or biochemical processes. However, the nature of the constituting "core" and of attachment of carbohydrate, nitrogen containing compounds like protein, phenolic compounds and metals to the core are unclear though various models are suggested. It is reviewed that some organic compounds, phenclic acids, derived from humic substances are effective on plant metablism in many cases, although the mechanisms are remained to be clarified.

• The Plant Pathology Journal
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• 제38권1호
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• pp.25-32
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• 2022

Plant pathogens pose major threats on agriculture and horticulture, causing significant economic loss worldwide. Due to the continuous and excessive use of synthetic pesticides, emergence of pesticide resistant pathogens has become more frequent. Thus, there is a growing needs for environmentally-friendly and selective antimicrobial agents with a novel mode of action, which may be used in combination with conventional pesticides to delay development of pesticide resistance. In this study, we evaluated the potentials of lichen substances as novel biopesticides against eight bacterial and twelve fungal plant pathogens that have historically caused significant phytopathological problems in South Korea. Eight lichen substances of diverse chemical origins were extracted from axenic culture or dried specimen, and further purified for comparative analysis of their antimicrobial properties. Usnic acid and vulpinic acid exhibited strong antibacterial activities against Clavibacter michiganensis subsp. michiganensis. In addition, usnic acid and vulpinic acid were highly effective in the growth inhibition of fungal pathogens, such as Diaporthe eres, D. actinidiae, and Sclerotinia sclerotiorum. Intriguingly, the growth of Rhizoctonia solani was specifically inhibited by lecanoric acid, indicating that lichen substances exhibit some degrees of selectivity to plant pathogens. These results suggested that lichen substance can be used as a selective biopesticide for controlling plant disease of agricultural and horticultural significance, minimizing possible emergence of pesticide resistant pathogens in fields.

• 한국가스학회지
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• 제11권3호
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• pp.13-18
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• 2007

다변량 통계 분석법(Multivariate statistical analysis method)의 대표적 방법인 다중 선형 회귀법(Multiple linear regression. MLR)을 이용하여 2성분계 혼합물의 인화점을 회귀 분석하고 예측하였다. 가연성 물질의 인화점에 대한 예측은 실제 화학 공정 설계에서 화재 및 폭발 위험성을 판단하는 중요한 부분 중의 하나이다. 본 연구에서는 순수 성분의 물성 자료만을 이용하여 2성분계 혼합물의 인화점 실험 자료에 대해 다중 선형 회귀법(MLR)을 수행하였고, 이를 이용하여 새로운 혼합물에 대한 인화점을 예측하였다. 2성분계 혼합물의 인화점에 대한 MLR의 회귀 성능과 새로운 혼합물에 대한 예측 성능을 알아보기 위해, 기존의 인화점 추정 방법인 Raoult의 법칙과 Van Laar식에 의한 추정값과 비교해 보았다.

• 대한화학회지
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• 제62권3호
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• pp.243-252
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• 2018

이 연구에서는 중학교 2학년 학생들의 물질의 특성에 대한 거시적, 미시적 수준의 개념을 비교하였다. 기초 입자 개념 검사와 녹는점, 용해도, 밀도 개념에 대한 거시적, 미시적 수준의 개념 검사를 개발하여 371명의 중학생들을 대상으로 실시하였다. 학생들의 응답을 거시적 수준과 미시적 수준의 개념 이해 여부에 따라 네 가지로 범주화하고 범주별 비율과 특징을 분석하였다. 연구 결과, 거시적 수준의 개념을 이해한 학생들은 미시적 수준에서 다양한 오개념을 가지고 있는 경우가 많았다. 많은 학생들은 물질의 특성과 관련한 미시적 수준의 개념뿐 아니라 거시적 수준의 개념 이해에도 어려움을 겪었다. 거시적 수준의 개념을 이해하지 못한 학생들은 대부분 미시적 수준에서 거시적 수준의 응답과 일치하는 응답을 하지 못하였다. 기초 입자 개념 문항에 옳은 응답을 한 학생들도 물질의 특성 관련 개념을 이해하는 데 어려움을 겪었으나, 거시적 수준의 개념을 이해한 경우 미시적 수준의 개념도 함께 이해한 비율이 높았다. 연구 결과를 바탕으로 물질의 특성 관련 개념의 효과적인 교수학습 및 향후 교육과정의 개선을 위한 교육적 시사점을 논의하였다.