Carson P. McCann;Michael G. Brandel;Arvin R. Wali;Jeffrey A. Steinberg;J. Scott Pannell;David R. Santiago-Dieppa;Alexander A. Khalessi
Journal of Cerebrovascular and Endovascular Neurosurgery
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v.25
no.4
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pp.380-389
/
2023
Objective: Middle meningeal artery embolization (MMAe) has burgeoned as a treatment for chronic subdural hematoma (cSDH). This study evaluates the safety and short-term outcomes of MMAe patients relative to traditional treatment approaches. Methods: In this retrospective large database study, adult patients in the National Inpatient Sample from 2012-2019 with a diagnosis of cSDH were identified. Cost of admission, length of stay (LOS), discharge disposition, and complications were analyzed. Propensity score matching (PSM) was utilized. Results: A total of 123,350 patients with cSDH were identified: 63,450 without intervention, 59,435 surgery only, 295 MMAe only, and 170 surgery plus MMAe. On PSM analysis, MMAe did not increase the risk of inpatient complications or prolong the length of stay compared to conservative management (p>0.05); MMAe had higher cost ($31,170 vs. $10,768, p<0.001) than conservative management, and a lower rate of nonroutine discharge (53.8% vs. 64.3%, p=0.024). Compared to surgery, MMAe had shorter LOS (5 vs. 7 days, p<0.001), and lower rates of neurological complications (2.7% vs. 7.1%, p=0.029) and nonroutine discharge (53.8% vs. 71.7%, p<0.001). There was no significant difference in cost (p>0.05). Conclusions: MMAe had similar LOS and decreased odds of adverse discharge with a modest cost increase compared to conservative management. There was no difference in inpatient complications. Compared to surgery, MMAe treatment was associated with decreased LOS and rates of neurological complications and nonroutine discharge. This nationwide analysis supports the safety of MMAe to treat cSDH.
Vivek Singh;Jeremy Loloi;William Macaulay;Matthew S. Hepinstall;Ran Schwarzkopf;Vinay K. Aggarwal
Hip & pelvis
/
v.34
no.2
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pp.96-105
/
2022
Purpose: Use of dual mobility (DM) articulations can reduce the risk of instability in both primary and revision total hip arthroplasty (THA). Knowledge regarding the impact of this design on patient-reported outcome measures (PROMs) is limited. This study aims to compare clinical outcomes between DM and fixed bearing (FB) prostheses following primary THA. Materials and Methods: All patients who underwent primary THA between 2011-2021 were reviewed retrospectively. Patients were separated into three cohorts: FB vs monoblock-D vs modular-DM. An evaluation of PROMs including HOOS, JR, and FJS-12, as well as discharge-disposition, 90-day readmissions, and revisions rates was performed. Propensity-score matching was performed to limit significant demographic differences, while ANOVA and chi-squared test were used for comparison of outcomes. Results: Of the 15,184 patients identified, 14,652 patients (96.5%) had a FB, 185 patients (1.2%) had a monoblock-DM, and 347 patients (2.3%) had a modular-DM prosthesis. After propensity-score matching, a total of 447 patients were matched comparison. There was no statistical difference in the 90-day readmission (P=0.584), revision rate (P=0.265), and 90-day readmission (P=0.365) and revision rate due to dislocation (P=0.365) between the cohorts. Discharge disposition was also non-significant (P=0.124). There was no statistical difference in FJS-12 scores at 3-months (P=0.820), 1-year (P=0.982), and 2-years (P=0.608) between the groups. Conclusion: DM bearings yield PROMs similar to those of FB implants in patients undergoing primary THA. Although DM implants are utilized more often in patients at higher-risk for instability, we suggest that similar patient satisfaction may be attained while achieving similar dislocation rates.
Background/Aims: To determine whether metformin, which is considered a host-directed therapy for tuberculosis (TB), is effective in improving the prognosis of patients with TB and diabetes mellitus (DM), who have higher mortality than those without DM. Methods: This cohort study included patients who were registered as having TB in the National Tuberculosis Surveillance System. The medical and death records of matched patients were obtained from the National Health Information Database and Statistics Korea, respectively, and data from 2011 to 2017 were collected retrospectively. We classified patients according to metformin use among participants who used diabetes drugs for more than 28 days. The primary outcome was all-cause mortality during TB treatment. Double propensity score adjustment was applied to reduce the effects of confounding and multivariable Cox proportional hazard models were used to estimate adjusted hazard ratio (aHR) with 95% confidence interval (CI). Results: The all-cause mortality rate during TB treatment was lower (9.5% vs. 12.4%, p < 0.01) in the metformin user group. The hazard of death due to all causes after double propensity score adjustment was also lower in the metformin user group (aHR 0.76, 95% CI 0.67-0.86, p < 0.01). There was no significant difference in mortality between metformin users and non-users for TB-related deaths (p = 0.22); however, there was a significant difference in the non-TB-related deaths (p < 0.01). Conclusions: Metformin use in patients with TB-DM co-prevalence is associated with reduced all-cause mortality, suggesting the potential for metformin adjuvant therapy in these patients.
Soo-Hyuk Yoon;Seungeun Choi;Susie Yoon;Kwon Joong Na;Jaehyon Bahk;Ho-Jin Lee
The Korean Journal of Pain
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v.37
no.4
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pp.354-366
/
2024
Background: Anesthetic agents are potential modifiable factors that can mitigate chronic postsurgical pain (CPSP) development. This study aimed to investigate the association between propofol-based total intravenous anesthesia (TIVA) and the occurrence of CPSP following video-assisted thoracoscopic surgery (VATS) for lung cancer resection. Methods: This single-center retrospective cohort study included adult patients with lung cancer who underwent elective VATS between January 2018 and December 2022. Patients were divided based on the maintenance anesthetic used (propofol vs. sevoflurane). The primary outcome was the presence of CPSP, defined as any level of surgical site pain recorded within 3-6 months postoperatively. The authors investigated the association between anesthetic agents and CPSP using propensity score matching with stabilized inverse probability of treatment weighting (sIPTW) to adjust for confounders. Additionally, multivariable logistic regression was used to further adjust for intraoperative opioid use that sIPTW could not account for. The robustness of these associations was evaluated using the E-value. Results: Of the 833 patients analyzed, 461 received propofol and 372 sevoflurane. The overall incidence of CPSP was 43.3%. After sIPTW, the use of TIVA was significantly associated with a lower incidence of CPSP (odds ratio [OR]: 0.75, 95% confidence interval [CI]: 0.57-0.99, P = 0.041), and remained significant after adjusting for intraoperative remifentanil equivalent dose (OR: 0.73, 95% CI: 0.55-0.96, P = 0.026). The E-values were 1.08 and 1.17, respectively. Conclusions: Propofol-based TIVA is associated with reduced CPSP occurrence in VATS for lung cancer. Further prospective studies are needed to confirm the results.
Ji Eun Jung;Jeong Ho Song;Seyeol Oh;Sang-Yong Son;Hoon Hur;In Gyu Kwon;Sang-Uk Han
Journal of Gastric Cancer
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v.24
no.4
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pp.356-366
/
2024
Purpose: The usability of a new surgical navigation system that provides patient-specific vascular information for robotic gastrectomy in gastric cancer remains unexplored for laparoscopic gastrectomy owing to differences in surgical environments. This study aimed to evaluate the applicability and safety of this navigation system in laparoscopic gastrectomy and to compare the post-operative outcomes between procedures with and without its use. Materials and Methods: Between June 2022 and July 2023, 38 patients across 2 institutions underwent laparoscopic gastrectomy using a navigation system (navigation group). The technical feasibility, safety, and accuracy of detecting variations in vascular anatomy were measured. The perioperative outcomes were compared with 114 patients who underwent laparoscopic gastrectomy without a navigation system (non-navigation group) using 1:3 propensity score matching during the same study period. Results: In all patients in the navigation group, no adverse events associated with the navigation system occurred during surgery in any patient in the navigation group. No accidental vessel injuries necessitate auxiliary procedures. All vessels encountered during the gastrectomy were successfully reconstructed and visualized. Patient demographics and operative data were comparable between the 2 groups. The navigation group exhibited a significantly lower overall complication rate (10.5%) than the non-navigation group (26.3%, P=0.043). Notably, pancreas-related complications were absent in the navigation group but occurred in eight cases in the non-navigation group (7.0%, P=0.093), although the difference was not statistically significant. Conclusions: The patient-specific surgical navigation system demonstrated clinical feasibility and safety for laparoscopic gastrectomy for gastric cancer, potentially reducing complication rates compared with laparoscopic gastrectomy without its use.
This studies has been carried out how to effect on electrostafic propensity of synthetic fabrics by coating with 0.5% acrylic polymer solution which was previously developed by the author to improve anticrease nature of silk. The work conditions are: (A) Applied synthetic polymer was acrylic polymer 525, developed by the author. (B) Electrostatic voltage for various fabrics were carried out by Korea standard abrasion partner with Korea standard (KS K 0905) cotton, nylon, polyester and the self sample fabric. (C) Applied fabrics for the investigations were carried out by using abrasion partner with Korea standard (KS K 0905) cotton, nylon, polyester and the self sample fabric. (D) Electrostatic propensity investigations were carried out by use of sample as silk, nylon, polyester and acrylic fabrics, seperating before finish or after finish. (E) Washing after the finish or the original fabric was carried out by Korea standard method, KS K 0465. Through the investigations, he happened to find many interesting matters and the obtained results are as followings. 1. Electrostatic voltage for the finished fabrics increased more than their original silk, nylon, acrylic fabrics except polyester fabric. (See Table 5) 2. Electrostatic voltage for the finished polyester against K.S. polyester decreased remarkably than the original fabric test. 3. In spite of no problem on electrostatic propensity of silk, it showed high electrostatic voltage between the same nature fabric abrasion, because silk is very weak against abrasion and because the test method had been developed to be useful for only synthetic fabrics. 4. Electrostatic voltage increased more in case of abrasion between different nature of fabrics than the same nature of fabrics. 5. Electrostatic voltage of each fabric increased by repeat of wash. 6. Many investigation data were followed with Contact Electrification Series Principle, another word, the farther each other located fabric on the series abrasion was, the higher electrostatic voltage. (See Fig. 6) 7. Such investigation gives warning of use on the mix fiber spinning service as far as concern with electrification. 8. It may also call attention for such increase of electrification in case any finishing of silk textile.
Total 83model forest owners in Korea were investigated to find out the relationship between their attitudes toward tree felling (or propensity to felling) and selected six independent variables, i.e, owner's age(X1), educational level(X2), forest land area (X3), socioeconomic status (X4), communication (X5) and sociopsychological factor(X6). The dependent variable was measured by Liken attitude scale, and analyzed by multiple regression. Major findings of the study are summarized as follows: 1) The degree of the propensity of felling is relatively high. The communication and sociopsychological variables are negatively, but education level is positively related to the dependent variable. 2) The multiple correlation coefficient between felling-attitude score and six independent variables is 0.5322. Of the variance of this sttitude score, about 13 percent can be explained by communication variable, 6 percent by sociopsychological variable and other 6 percent by age variable. 3) The model owners' attitudes toward felling are positively correlated with there sources of communication variable, i.e. personal contact, social participation and mass media contact. The multiple correlation coefficient between felling-attitude score and three sources of communication variable is 0.4049. This means that 16 percent of the variance of the attitude score can be explained by three sources of communication, that is, 9 percent by personal contact, 5 percent by social participation and 3 percent by mass media. 4) The fatalistic, untrustful and non-ambitious personalities were positively, but conservative personality negatively related to the propensity to tree felling. The multiple correlation coefficient between seven different personalities and the dependent variable is 0.5461. Of the variance of the dependent variable, 11 percent can be explained by untrustful personality, and other 11 percent by nonambitious personality.
Kim, Young-Tak;Kim, Hae-Rim;Park, Young-Ju;Lee, Hae-Pyeong
Proceedings of the Korea Institute of Fire Science and Engineering Conference
/
2008.11a
/
pp.450-455
/
2008
We have carried out the test using the cone calorimeter and the smoke density chamber to evaluate the characteristics of the combustion for the car interior materials passed horizontal burning test. We have analysed many parameters related to fire hazard. These parameters are the ignition time, the heat release rate, the maximum average rate of heat emission, the flashover propensity and specific optical density. There was a significant difference in HRR and optical smoke density. The HRR was $185{\sim}446kW/m^2$ and optical smoke density was $119{\sim}1207$. Only horizontal burning test was performed to evaluate the fire hazard for the car interior materials.
Transactions of the Korean Society for Noise and Vibration Engineering
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v.18
no.10
/
pp.1042-1048
/
2008
Disc brake noise is an important customer satisfaction and warranty issue for many manufacturers as indicated by technical literature regarding the subject coming from Motor Company. This research describes results of a study to assess disk brake squeal propensity using finite element methods and optimal technique (Kriging). In this study, finite element analysis has been performed to determine likely modes of brake squeal. This paper deals with friction-induced vibration of disc brake system under contact friction coefficient. A linear, finite element model to represent the floating caliper disc brake system is proposed. The complex eigen-values are used to investigate the dynamic stability and in order to verify simulations which are based on the FEM model. In this paper, Kriging from among the meta-modeling techniques is proposed for an optimal design scheme to reduce the brake squeal noise.
The purpose of the study was to provide the informations about the economic status of elderly households. Utilizing the 1996 national household data, economic status was investigated by the components of two financial statements: the income and expense statement and the balance sheet statement. Thus it included incomes, consumption, propensity to consume, savings(financial assets), debt amount and net-savings. The elderly households were compared with the nonelderly households. The subgroups of the elderly were also compared. They were divided based on the employment status of the head and household composition. The results showed that the economic status of the elderly was worse compared to the nonelderly. There were also variations among the subgroups of the elderly households. In general, the economic status of retired households and single households were worse than those of employed households and of the households composed of couple and the elderly living with children.
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