• 한국콘텐츠학회논문지
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• 제9권12호
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• pp.467-476
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• 2009

웹 기술과 교육 환경의 급속한 발전으로 웹기반 협동학습 시스템이 많은 관심을 받고 있다. 최근에는 협동학습에 학습의 흥미와 능동적 참여를 높일 수 있는 게임을 접목하는 연구들이 등장하고 있다. 이러한 연구들은 게임을 사용하는 TGT 학습 모델에 기반한 것들로 대부분 시스템 설계 제안 수준에 머물렀으며, 구현 연구도 순수 TGT 모델만을 구현해 여러 문제점들을 가지고 있었다. 본 논문에서는 이러한 문제점들을 해결하기 위해 확장된 TGT 모델을 정의하고 이에 기반한 새로운 웹기반 협동학습 시스템을 제안하였다. 확장 부분은 Jigsaw II 모델의 전문가 학습, STAD 모델의 향상점수 아이디어, 피드백 학습을 위한 학습자의 게임 문제 출제 참여 등을 포함한다. 순수 TGT 모델 기반 시스템에 대한 제안 시스템의 유용성을 검증하기 위해 두 시스템을 실제 중학교 두 반에게 적용하여 실험을 하였으며 그 결과 제안 시스템이 비교 시스템보다 더 나은 결과를 보임을 보였다.

• 복식문화연구
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• 제14권5호
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• pp.864-875
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• 2006

The characteristics of the demographics in Korea as it gets older are the increase of Elderly Women and continuous progress in urbanization. In this study, body shapes are classified as standard, obese, and tiny according to the previous studies based on the body shape characteristics and the body measurement of the Elderly Women. Based on the classification, we developed prototype of the panty for the Elderly Women to provide basic materials for the quality enhancement of the clothing of the increasing Elderly Women. The followings are the result of the study. 1. To categorize the body shapes of the Elderly Women focusing on the lower half, we grouped the target subjects using the nested approach by the average standard deviation and the factor analysis minimal diffusion method. Accordingly, type 1 and 2 had 36 members respectively and type 3 had 43 members. In this study, two Elderly Women subjects with standard body shape falling under the type 1 were selected as the subjects. 2. In the second trial evaluation for the prototype panty for the Elderly Women 32 items for appearance test and 3 items for functional test were evaluated. The scores in leg, sideline and hip were shown high and the balance between the parts was maintained very well. In the functional test, the panty used to be too tight for the leg curve but in the second trial it was improved, too. In each item, the second trial test showed better score than the first trial test. Conclusively, the most optimal panty prototype for the Elderly Women was proposed according to the trial test result.

• 대한약침학회지
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• 제20권2호
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• pp.132-138
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• 2017

Objectives: We report the results of three case studies on the clinical efect of ascending kidney water and descending heart fre (AKDH) pharmacopuncture on patients with Hwa-Byung. Methods: Tis study involved three patients, all female, who had been admitted to a hospital of traditional Korean medicine and had been diagnosed as having Hwa-Byung by using the Hwa-Byung Structure Clinical Interview for DSM-IV. AKDH pharmacopuncture is administered by injecting pharmacopuncture at a specifc acupoint to change from a state of water-fre disharmony to one of water-fre harmony. For our three patients, Hwangyeonhaedoktang (黃連解毒湯) pharmacopuncture was injected at GB21 and GB20 on both sides; a total of 0.4 cc was injected, with 0.1 cc being injected at each point. Fel ursi, Bezora bovis and moschus (BUM) pharmacopuncture was injected at CV17, CV12, and CV6; a total of 0.15 cc was injected, with 0.05 cc being injected at each point. Treatment was done daily. Progress was evaluated using the Hwa-Byung diagnostic interview (HBDIS), beck depression inventory (BDI), and numeric rating scale (NRS) scores. Results: For the frst patient (case 1), after treatment, the HBDIS score was reduced from 44 to 30 points, the BDI score from 37 to 14, and the NRS score from 10 to 7. For the second patient (case 2), after treatment, the HBDIS score was reduced from 41 to 27 points, the BDI score from 13 to 7, and the NRS score from 10 to 5. For the third patient (case 3), after treatment, the HBDIS score was reduced from 42 to 28 points, the BDI score from 12 to 9, and the NRS score from 10 to 4. Conclusion: Ascending kidney water and descending heart fre pharmacopuncture treatment can be efective for improving ascending kidney water and descending heart fre energy and can be used to alleviate Hwa-Byung.

• Communications for Statistical Applications and Methods
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• 제18권3호
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• pp.287-294
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• 2011

동료평가는 일반적으로 교육 분야의 평가시스템에서 같이 학습을 하는 동료가 평가자가 되어 상대 학습자의 과정이나 결과물에 가치를 부여하는 것으로서, 많은 장점을 갖고 있음에도 불구하고 단순히 부여 받은 점수들의 평균을 계산하여 기여도를 산정한다는 단점 또한 갖고 있어 이를 개선하기 위한 다각적인 연구가 진행되어 오고 있다. 그런데 이들 선행연구에서 활용된 카이제곱 검정이나 유의확률 등의 개념은 동료평가를 활용하는 교육학이나 산업공학 분야에 종사하는 사람들에게는 쉬운 개념이 아니다. 이에 본 연구에서는 표준편차라는 간단한 통계를 이용하지만, 이들과 유사한 결과를 보이면서도 방법적인 측면에서 매우 간단한 동료평가의 가중치 부여방법을 제안하였다. 더불어 제안된 방법의 용이성과 효용성 및 활용 예에 대해서도 알아보았다. 본 연구는 간이분석법을 이용하여 이용자의 편리성을 증대시키는데 기여할 수 있다고 사료되는 바, 이러한 측면에 본 연구의 의의가 있다고 하겠다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7669-7674
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• 2013

Background: The hypothesis that patients who primarily progress on two consecutive chemotherapy regimens without evidence of clinical benefit may opt for supportive care was investigated. The purpose was to determine the quality of life in recurrent ovarian cancer patients choosing to receive salvage chemotherapy in addition to supportive care or palliative care alone. A secondary objective was to evaluate factors that affect quality of life in ovarian cancer patients. Materials and Methods: A descriptive study was conducted in patients who had histological confirmed epithelial ovarian cancer and failed to respond to at least one regimen of chemotherapy, coming for treatment at the King Chulalongkorn Memorial Hospital in Bangkok, Thailand over a six-month period from August 2012-March 2013. Each patient was asked to complete the FACT-G and a general personal questionnaire. The median quality of life score was analyzed. The Mann Whitney U Test was used to compare the difference between salvage chemotherapy and palliative care groups, and the Kruskal Wallis was used to evaluate other variables. Results: Thirty-eight ovarian cancer patients were identified who failed to respond to chemotherapy. Of the 38, 30 chose salvage chemotherapy and eight palliative care for further treatment. By histology the carcimnomas were predominantly endometrioid subtype and poorly differentiated. The majority of patients in this study had FIGO stage III, and ECOG status 0-1. The median quality of life score was 76.3 (35.8-94.0), with no significant differences between the groups. Factors associated with the quality of life were the ECOG score and number of chemotherapeutic courses. Conclusions: In the setting of refractory or recurrent epithelial ovarian cancer, patients who receive salvage chemotherapy have comparable quality of life scores with patients treated with palliative care alone, providing a contrast with previous studies.

• Clinical and Experimental Pediatrics
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• 제60권2호
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• pp.38-44
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• 2017

Purpose: Kawasaki disease (KD) is an immune-related multisystemic vasculitis that occurs in children, especially ensuing from a coronary artery abnormality. Sodium level is known to be related to vascular injury, which could affect the progress of KD. The purpose of this study was to determine the serum sodium levels that could predict the occurrence of cardiac and coronary artery events in KD. Methods: We conducted a retrospective review of medical records for 104 patients with KD from January 2015 to December 2015. Patients with serum Na levels of <135 mEq/L at the time of initial diagnosis were assigned to the hyponatremia group. Laboratory findings and echocardiographic data were analyzed for various aspects. Results: Among the 104 patients with KD, 91 were included in the study, of whom 48 (52.7%) had hyponatremia. The degree of fever, white blood cell count, percentage of neutrophils, percentage of lymphocytes, total bilirubin level, brain natriuretic peptide level, erythrocyte sedimentation rate, and C-reactive protein level were higher in the patients with hyponatremia. They also demonstrated a trend of larger coronary artery diameters based on Z scores. Conclusion: The severity of vascular inflammation in acute KD with hyponatremia might worsen the prognosis of coronary vasculature. Although no statistically significant correlation was found between the initial serum sodium levels and coronary arteriopathy in the patients with KD in this study, a long-term follow-up study with a larger number of enrolled patients should be designed in the future to elucidate the relationship between serum sodium level and coronary arteriopathy in patients with KD.

• 한국축산식품학회지
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• 제37권3호
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• pp.418-428
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• 2017

In this study, the effects of pre-converted nitrite from Swiss chard powder (PS) on the color stability and shelf-life of cooked pork patties during refrigerated storage for 28 d were investigated. Nitrite was added at a concentration of approximately 120 ppm. Five treatments were formulated as follows: Control (120 ppm nitrite), T1 (2% PS), T2 (2% pre-converted nitrite from celery powder; PC), T3 (1% PS + 60 ppm nitrite), and NC (nitrite-free). The T1 and T3 samples had higher nitrosoheme pigment contents, which were associated with the redness of the samples (p<0.05). T1 resulted in the highest redness value (p<0.05). The redness and yellowness of the cooked pork patties increased with increasing PS levels. The pH of the samples subjected to all treatments decreased with progress of the storage period (p<0.05). The pH of the T1 and T3 samples treated with PS was lower (p<0.05) than that obtained with other treatments, as PS has a lower pH value. The treatments in which PS was added were most effective for reducing the level of thiobarbituric acid reactive substances (TBARS) and the residual nitrite content relative to the control. T1 resulted in the highest flavor, off-flavor, and overall acceptability scores during storage (p<0.05). The total viable bacterial count for all treatments was below 1 Log CFU/g, and E. coli and coliform bacteria were not detected during storage. Therefore, these results suggested that pre-converted nitrite from Swiss chard powder is a potential replacement for nitrite in meat products.

• Asian Pacific Journal of Cancer Prevention
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• 제15권17호
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• pp.7091-7095
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• 2014

Background: The study aimed to evaluate the incidence of CpG island promoter methylation of BMP6, a member of the transforming growth factor beta family, in tissue samples from colorectal cancers (CRC) and look for its association with BMP6 expression and clinicopathological correlation. Materials and Methods: Methylation specific PCR for the BMP6 promoter region was performed with 85 frozen tissue samples of CRC and 45 of normal colon. Methylation status of MLH1 was also determined by the same method. Expression of BMP6 was evaluated by immunohistochemistry (IHC), using Allred's scoring system. The methylation status was analyzed against clinical and pathological parameters in CRC. Results: The study revealed BMP6 hypermethylation in 34 of 85 tumor specimens (40%), and 15 out of 45 normal tissue samples from CRC (33%). The incidence of hypermethylation was inversely correlated with IHC score. Allred's scores of 7 or more were correlated with lower frequency of BMP6 hypermethylation (29% compared to 50% in the remaining, p-value 0.049). However, there was no association between hypermethylation status and any clinicopathological parameters. The methylation status of BMP6 was not correlated with that of MLH1, a key methylation determinant in CRC. On survival analysis, there was no significant difference in progress-free survival (PFS) between the cases with and without hypermethylation (2-year PFS 74% and 76%, respectively). Conclusions: CpG island methylation of BMP6 is found in high frequency in CRC and this epigenetic event is associated with suppressed protein expression in the tumor tissue. However, the marker is not associated with tumor progression of the disease.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2007년도 추계학술대회 논문집
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• pp.1852-1857
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• 2007

지하철 초기 도입 후 한국형 표준전동차 생산단계까지 눈부신 발전을 하였으나 철도법을 알지 못하거나 관계자이 아닌 기술자가 전동차 디자인을 하여 아쉬운 점이 남는다. 앞으로 도입하는 첨단기술과 열정으로 이룬 전기동차(이하 전동차), 수십 대의 전동차를 동시에 여객 영업운전은 안전운행을 위한 열차운영내규에 맞추어야 하는 등 까다로운 점이 있고, 이것에 대한 면밀한 검토가 있어야 한다. 기존 전동차는 자동차처럼 메이커에 따라 비슷한 것과 종류와 특성이 조금씩 다르고, 그중 가장 보유량수가 많고, 높은 비중을 차지하고 있는 영국에서 기술 도입하여 대우에서 만든 GEC전동차의 전동차 순기능 대책강화방안을 논하고자 한다.

• Journal of Korean Biological Nursing Science
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• 제7권2호
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• pp.31-48
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• 2005

Purpose: Studies focus on cancer control, prevention, or assessment of psychosocial problems and intervention methods. However, few studies exist concerning psychosocial problems, measuring tools for those problems, and interventions for cancer patients in Korea. One of the purposes of this study was to review studies in this area, to examine various psychosocial problems experienced by cancer patients. This is a crucial area to investigate, since psychosocial problems in turn negatively influence the patients' immune function, which speeds the progress of the disease. Another goal was to identify instruments used to measure psychosocial functioning and problems in cancer patients, to analyze their validity and reliability, with the aim to discover the best instruments. A final goal was to explore and compare the effects of psychosocial interventions, to determine the most effective practices. Method: Journal articles published since 1995 were searched from PubMed Data base, Google search engine, and published cancer-related studies, using search keywords "psychosocial function and intervention for the cancer patients"; whole articles of selected references were reviewed and analyzed. Result: Most common psychosocial problems were depression, fatigue, nausea, pain, distress, resulting in a low quality of life. The seven scales found in the literature to assess the psychosocial functioning were Center for Epidemiological Studies-Depression, State-Trait Anxiety Inventory, Symptom Checklist 90-R, Profile of Mood States, Psychosocial Adjustment to Illness Scale, Brief Symptom Inventory, and SF-36 HRQOL(Health Related Quality of Life). Social support interventions for cancer patients were effective in improving quality of life scores. Conclusion: It is necessary to apply support intervention strategies to help cancer patients in Korea. These strategies can help to reduce the effects of psychosocial symptoms, which in turn affect the development and control of cancer. Strategies developed in Western countries may need to be modified for use within Korea. Further studies are warranted to review the support intervention strategies that were being used to for cancer patients