• 대한한방부인과학회지
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• 제19권2호
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• pp.240-260
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• 2006

Purpose : The objective of this study is to serve guidelines for the investigation and management of uterine myomas with KM therapies. Methods : English-language articles from PubMed and Korean-language articles from the database of the journal of oriental gynecology were reviewed from 2000 to 2005, using the key words 'uterine myoma', 'uterine leiomyoma', 'fibroid', 'uterine artery embolization', 'endometrial ablation', 'myomectomy', and jagungguenjong(子宮筋腫)'. Results and Limits : The areas of clinical practices considered in formulating this guideline are assessment, KM therapies, medical treatments, myolysis, selective artery occlusion, endometrial ablation and surgical therapies including myomectomy and hysterectomy. Implementation of this guideline would optimize the decision-making process of women with uterine myomas and further investigation or therapy of their KM doctors. But we don't have abundant evidences of clinical trials of uterine myoma treated with KM therapy, though we treat or manage that with every-day clinical practices. Moreover cultural gaps between Korea and other western countries make many differences in the attitude to surgical therapies, especially hysterectomy. So it is very difficult to compare W therapies with other therapies. Moreover it is much difficult to estimate cost-effectiveness and benefit of those therapies in QOL. Conclusions : The majority of uterine myoma is asymptomatic and will not require any intervention or further investigation. But unmarried women who wish to marry and get pregnant want to find safe therapy for their asymptomatic uterine myomas. In that case, most of the patients prefer non-surgical therapy to surgical therapy. So KM herbal medicinal therapy is a good alternative method for those patients. For the symptomatic myomas, hysterectomy offers a definitive solution. However, it is not the best solution for women who wish to preserve their uterus. So KM therapy is a good alternative for them. But the predicted benefits of alternative therapies including KM therapy must be carefully weighed against the Possible risks of these therapies. To improve the quality of life of both women with asymptomatic and symptomatic myomas, selecting and treating patients should be done carefully. Moreover, the effect of KM therapy has to evaluated, comparing the possible situation without treatment and the benefit of constant treatment as a health-care system.

• 방사성폐기물학회지
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• 제15권3호
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• pp.191-197
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• 2017

한국원자력연구원은 IAEA에서 권고하고 있는 안전조치기반설계(SBD)에 입각하여 파이로 안전조치 기술을 개발하고 있다. 한국원자력연구원은 파이로 안전조치접근방안 개발을 위한 IAEA 회원국지원프로그램(MSSP)을 수행하였다. IAEA 회원국 지원프로그램을 통하여 기준파이로시설(REPF) 개념을 설계하고, 이 시설에 대한 안전조치시스템을 개발하였다. 최근에 기준파이로시설은 용량이 증대된 REPF+로 업데이트 되고 있다. 핵물질계량관리시스템 성능평가를 위하여 전산코드 PYMUS를 개발하였으며, PYMUS는 전용탐지획률 통계평가 방안을 포함하여 업그레이드하고 있다. 파이로 입력물질 계량을 위한 비파괴분석장비로 ASNC가 개발되고 있으며, 파이로 출력물질인 U/TRU 잉곳을 계량하기위한 비파괴분석장비로 HIPAI가 개발되고 있다. 또한 컴프톤 억제 감마선분광기술, LIBS 기술, 균질화 공정의 샘플링 오차에 대한 평가도 진행 중이다. 이러한 노력들은 국내에서 선진핵주기기술 실현에 크게 기여할 것이다.

• 한국농공학회논문집
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• 제59권1호
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• pp.21-30
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• 2017

Soil erosion has been issued in many countries since it causes negative impacts on ecosystem at the receiving water bodies. Therefore best management practices to resolve the problem in a watershed have been developed and implemented. As a prior process, there is a need to define soil erosion level and to identify the area of concern regarding soil erosion so that the practices are effective as they are designed. Universal Soil Loss Equation (USLE) were developed to estimate potential soil erosion and many Geographic Information System (GIS) models employ USLE to estimate soil erosion. Sediment Assessment Tool for Effective Erosion Control (SATEEC) is one of the models, the model provided several opportunities to consider various watershed peculiarities such as breaking of slope length, monthly variation of rainfall, crop growth at agricultural fields, etc. SATEEC is useful to estimate soil erosion, however the model can be implemented with ArcView software that is no longer used or hard to use currently. Therefore SATEEC based on ArcView was rebuild for the ArcGIS software with all modules provided at the previous version. The rebuilt SATEEC, ArcSATEEC, was programmed in ArcPy and works as ArcGIS Toolset and allows considering monthly variations of rainfall and crop growth at any watershed in South-Korea. ArcSATEEC was applied in Daecheong-dam watershed in this study, monthly soil erosion was estimated with monthly rainfall and crop growth variation. Annual soil erosion was computed by summing monthly soil erosion and was compared to the conventional approach to estimate annual soil erosion. The annual soil erosion estimated by the conventional approach and by summing monthly approach did not display much differences, however, ArcSATEEC was capable to provide monthly variation of soil erosion.

• 대한의용생체공학회:의공학회지
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• 제32권3호
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• pp.237-244
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• 2011

In this paper, a feature-based registration technique is proposed for pre-contrast and post-contrast lung CT images. It utilizes three dimensional(3-D) features with their descriptors and estimates feature correspondences by nearest neighborhood matching in the feature space. We design a transformation model between the input image pairs using a free form deformation(FFD) which is based on B-splines. Registration is achieved by minimizing an energy function incorporating the smoothness of FFD and the correspondence information through a non-linear gradient conjugate method. To deal with outliers in feature matching, our energy model integrates a robust estimator which discards outliers effectively by iteratively reducing a radius of confidence in the minimization process. Performance evaluation was carried out in terms of accuracy and efficiency using seven pairs of lung CT images of clinical practice. For a quantitative assessment, a radiologist specialized in thorax manually placed landmarks on each CT image pair. In comparative evaluation to a conventional feature-based registration method, our algorithm showed improved performances in both accuracy and efficiency.

• 농약과학회지
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• 제11권2호
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• pp.87-94
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• 2007

본 연구는 Pyrethroid계 살충제인 deltamethrin의 작업자 노출을 평가하기 위해 약제살포 환경의 공기중 농도분석과 아울러 인체내에 흡수되어 요중으로 대사되는 산물인 3-PBA의 최적 분석법을 확립하였고, deltamethrin과 3-PBA간의 상관성을 분석하였다. 3-PBA의 가수분해 최적 조건은 시료에 HCl을 첨가하여 pH1 로 조절한 후 $90^{\circ}C$에서 60분 동안 반응시켰을 때 이었다. 요 시료는 Amberlite XAD-16에 흡착시킨 후 acetone을 0.1 mL $min^{-1}$의 속도로 3mL에서 최고의 회수율을 나타내었다. 공기중 deltamethrin의 농도는 N.D. ${\sim}0.00079\;mg\;m^{-3}$이었고, 요중 3-PBA 농도는 $467.5{\pm}2.4\;{\mu}g\;g^{-1}$ creatinine이었다.

• 한국구조물진단유지관리공학회 논문집
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• 제17권2호
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• pp.10-20
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• 2013

보 구조물의 안전성을 평가하기 위해서, 해당 부재의 구조적 상태를 보여주는 보여줄 수 있는 변형률을 기반으로 한 모니터링 시스템이 이용되고 있다. 하지만 최대 변형률과 같은 부재의 상태를 대표할 수 있는 변형률이 발생하는 정확한 위치에 센서를 설치하지 않은 한, 계측된 변형률을 토대로 합리적인 평가를 할 수 있게 하는 추가적인 프로세스가 필요하다. 이에 따라 본 연구는 변형률계에 의해 계측된 이산데이터를 이용하여 강재 보 구조물의 변형률 분포를 추정하는 기법을 제안한다. 본 기법에서는 보 구조물에 작용하는 하중을 미지의 하중으로 가정하였기 때문에, 실제 적용성을 향상 시켰다. 최종적인 변형률 분포는 회귀 분석을 통해서 함수 형태로 주어진다. 본 기법을 이용한 추정 성능을 검증하기 위해서 분포하중, 집중하중, 모멘트가 동시에 작용하는 강재 보 구조물의 휨 실험을 수행하였다. 실험을 통해 추정 변형률의 값을 직접 계측한 값과 비교해 본 결과, 임의의 위치에서도 절대 오차 $2.32{\mu}{\varepsilon}$ 이내로 변형률을 추정할 수 있었으며, 전체 변형률 분포는 3.32% 이내의 상대오차로 얻을 수 있었다. 따라서 강재 보 모니터링 시스템에 효과적으로 적용할 수 있을 것으로 기대된다.

• 대한공간정보학회지
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• 제9권2호
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• pp.29-36
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• 2001

본 논문은 enterprise CIS 기반의 강원도 재해관리시스템 개발에 관해 기술하였다. 이 프로젝트는 '강원 종합 GIS 21 계획'의 일환으로 이루어졌다. 재해방재과에서는 2년 프로젝트로서 재해 관리시스템을 개발하는 중이며, 산림, 문화, 환경, 관광 등의 측면에서 사업타당성을 분석하였다. GIS 구축 1단계에서는 반년이상을 재해관리의 필요성에 대해 초점을 두어 연구하였다. 계획과정에서 강원도 전체 지역에 대한 장기적인 정보가 필요하였다. 또한 평가와 응답단계에서는 기상청과 다른 기관으로부터의 실시간 자료가 요구되었다. 이런 모든 정보는 주의 깊게 분석되고 참조되었다. ESRI의 새로운 GIS기술은 자연 재난/재해에서의 문제점을 해결해주었다. 예를 들어 위험물질의 이동경로는 도로망 분석을 통해 최소비용 경로를 찾는데 도움을 주었고, 물질을 운반하는 차량의 출발지와 도착지를 선택할 수 있었다. 또한 재해지역으로부터의 사람과 재산에 대한 최단시간내의 대피계획을 수립함으로써 재해문제의 전반적인 위험과 비용을 최소화할 수 있었다.

• 산업경영시스템학회지
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• 제41권3호
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• pp.72-82
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• 2018

In this paper, we identify risk factors that are likely to occur during the lifecycle of a new product development (NPD) project from the literatures, and identify the three objectives or three constraints that will ultimately be achieved for project success in the ICT industry : performance (scope/quality), schedule (time), and cost. Firstly, we interviewed the project experts to classify the risk factors according that the final project objectives are changeable based on scope/quality, time and cost budget constraints. Secondly, the survey for pairwise comparisons between the risk factors was asked to the project managers and members who had ever actually participated in the NPD projects of ICT industry to determine the priority ranks on relative importance using AHP (Analytic Hierarchy Process). The risk factors negatively affecting the goals of projects were analyzed by using the AHP respectively in four project stages during the life cycle of the project. The comparison of risk factors within each stage is a different approach unlike the literatures which have covered project's overall risk assessment. There is an advantage that risk management can be effectively performed with priorities according to each stage from the start to the end of the project. In other words, it is necessary to identify what risk factors will occur in each stage, and to have ideas at each stage with the priorities so that they can be mitigated and eliminated before actual occurrence. As a result, risks on scope & quality changes were found to be the most important considerations for initiative stage of NPD projects in the ICT industry, whereas in the final stage, risks on schedule (time) changes were the most important priorities. Among the ICT industry product categories, 'communication and broadcasting devices' and 'IT and communication based devices' generally have a high priority in terms of risks on scope & quality changes when initiating the project. At the closing stage of the project, however, considering that schedule (time) changeable risk is getting higher, these products tend to target at B2B market rather than B2C because the new products must be delivered and launched in time as customer firm required.

• 한국보건간호학회지
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• 제4권1호
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• pp.5-16
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• 1990

'What is nursing' this question could always be arised and such a question could bring forth the new possibility to definete the nursing concept more clearly. At the middle of 19th Centry, Mrs. Nightingale defined the concept of nursing as follows; 'Nursing is a kind of treatment act to aid the patient so that the health of patients may be recovered naturally, as keeping the most comfortable circumstances.' But after then, the role and function of nurses about purpose and method of nursing has continuously been studied, as the social circumstance has been changed. The fact that care provider and client have the same concept about nursing is very important at the first step of assessment. But at the present time, the care provider and client have not same concept yet, so the difference of unrsing concept between care provider and client is analyzed in this study. This study would be belived to be helpful for the advance of nursing in the future. In this study, 20 questionare from nursing objectives developed by Abdellah(basic care needs, sustenal care needs, remedial care needs and restorative care needs) are used for adult. The data of this study by the 6 point rating scale are analyzed by SAS as follows; 1. Respondent's view is that nursing is necessary in case of group(school or company) rather than private and in case of abnormal conditions rather than normal conditions. 2. Every questionares of nursing objectives are divided into 4 points of view such as basic care needs, sustenal care needs, remedial care needs and restorative care needs are examined. The evaluation by 6 point rating scale revealed that $5.08\pm0.65$ point in basic care needs $4.93\pm0.68$ point in sustenal care needs $4.91\pm0.80$ point in remedial care needs and $4.61\pm0.91$ point in restorative care needs. While basic care needs and substenal care needs that need more physical care show high points, remedial care needs and restorative care needs that need more psychological, social and spiritual care show low points. 3. It was checked whether there is any significant difference between above 4 point of views in nursing objectives and qeneral characteristics or not. As a result, there is significant difference between 4 point of view and ages, educational level, marriage, composition of children. And also there is significant difference between religion and basic care needs, remedial care needs and restorative care needs. But there is no significant difference between any point of view and sex, occupation, experience of admission and experience of family admission. As this study is based on the data gethered from a restricted area, the result can not represent the opinion of all the clients. Therefore the same kind of study should be carried out on many areas repeatedly and also it should be tried to extract objective concept. And also periodical study is needed to observe the changing process of nursing concept.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제33권1호
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• pp.46-54
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• 2007

PURPOSE Osteosarcoma occurring in the head and neck region is known as a malignant tumor that shows a relatively poor prognosis and, despite various treatments, clinicians have often been confounded by it. The existence or non-existence of the mutation of the gene $p16^{INK4a}$ has been used in prognosis assessment. In this study, author have attempted to determine whether methylation of the gene $p16^{INK4a}$ could be applied to forecast the progress of osteosarcomas in the head and neck region having been given poor prognoses in the diagnostic process and the early stage of treatment. RESEARCH SUBJECT AND METHOD Clinicopathologic investigations, immunohistochemical examinations, a methylation specific polymerase reaction (MSP) analysis, and a survival analysis were conducted on the tissues of 20 patients with mandibulofacial osteosarcoma. RESULTS Neither age, sex, size, smoking or non-smoking, nor region have showed a statistical significance with methylation or unmethylation of the gene $p16^{INK4a}$ and expression rates demonstrated by immunohisto- chemical examinations. A chi-square test indicated that recurrence inclination has no relation with the expression rate of p16 protein (p=0.6615), but it showed a statistical significance with methylation of the gene $p16^{INK4a}$ (p=0.0033). With respect to investigations of the survival rates, a Kaplan-Meier survival analysis found that the manifestation rate of p16 protein did not have an impact on survival (p=0.8864), but that the methylation of the gene $p16^{INK4a}$ resulted in significant differences in survival rates (p=0.0105). CONCLUSIONS The above results show that methylation of the gene $p16^{INK4a}$ could be one of the major factors that help determine the recurrence inclination and prognosis of osteosarcomas occurring in the head and neck region.