• Title/Summary/Keyword: Process Heat Application

Search Result 473, Processing Time 0.033 seconds

Anti-inflammatory Effects of Heat-treated Starfish Extract in Lipopolysaccharide-stimulated RAW 264.7 Cells (열처리 불가사리 추출물의 항염 활성)

  • Park, Jae Hyeon;Ahn, Keun Jae;Lee, Sun-Ryung
    • Journal of Life Science
    • /
    • v.30 no.7
    • /
    • pp.634-639
    • /
    • 2020
  • Starfish are a potential source of marine materials, but their unique odor can limit application. Our previous work suggested that brittle star Ophioplocus japonicus extract could be more effective as a cosmetic material by reducing its odor through a roasting process. However, the biological properties of heat-treated Ophioplocus japonicus extract (HOJE) remain poorly understood. We here examined the anti-inflammatory potential of HOJE in lipopolysaccharide (LPS)-induced RAW 264.7 cells. HOJE significantly inhibits LPS-stimulated nitric oxide (NO) production without affecting cell viability in a dose-dependent manner and suppresses LPS-induced expression of inducible nitric oxide synthases (iNOS) and pro-inflammatory cytokines such as interleukin-6 and -1β. Furthermore, treatment of pyrrolidine dithiocarbamate to inhibit nuclear factor kappa B (NF-κB) signaling accelerated the inhibitory effect of HOJE on NO production, and the translocation of NF-κB p65 from the cytosol to the nucleus was attenuated by HOJE. These results show that HOJE ameliorates inflammation partly through NF-κB signaling which consequently suggests that it has anti-inflammatory potential.

Development of Chitosan Coated Solid Lipid Nano-particles Containing 7-Dehydrocholesterol (7-디하이드로콜레스테롤을 함유한 키토산 코팅 처리 Solid Lipid Nano-particle의 개발에 관한 연구)

  • Lee Geun-Soo;Kim Tae-Hoon;Lee Chun-Il;Pyo Hyeong-Bae;Choe Tae-Boo
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.31 no.2 s.51
    • /
    • pp.141-146
    • /
    • 2005
  • Unstable cosmetic active ingredients could rapidly break down in chemical and photochemical process. Therefore, it has become a very important issue to encapsulate active ingredient for the stabilization. 7-Dehydrocholesterol (7-DHC), a precursor of vitamin $D_3$, has been shown to increase levels of protein and mRNA for heat shock protein in normal human epidermal keratinocytes. However, topical dermal application of 7-DHC is restricted due to its poor solubility and chemical unstability. In this study, 7-DHC was incorporated into nano-emulsion (NE), solid lipid nano-particle (SLN), and chitosan coated solid lipid nano-particle (CASLN), respectively. In order to prepare NE and SLN dispersion, high-pressure homogenization at temperature above the melting point of lipid was used Hydrogenated lecithin and polysorbate 60 were used as stabilizer for NE and SLN. CASLN was prepared by high speed homogenizing after adding chitosan solution to the SLN dispersion and showed positively charged particle properties. Decomposition rate of 7-DHC in NE, SLN and CASLN was studied as a function of time at different temperature. Differential scanning calorimetry (DSC) and X-ray diffraction (XRD) studies were performed to characterize state of lipid modification. It appeared that CASLN is the most effective to stabilize 7-DHC and may be used for a useful topical dermal delivery system.

Application of Porous Nanofibers Comprising Hollow α-Fe2O3 Nanospheres Prepared by Applying Both PS Template and Kirkendall Diffusion Effect for Anode Materials in Lithium-ion Batteries (커켄달 효과와 주형법을 통해 합성한 α-Fe2O3 중공입자로 구성된 다공성1차원 구조체의 리튬 이차전지 음극활물질 적용)

  • Lee, Young Kwang;Jeong, Sun Young;Cho, Jung Sang
    • Korean Chemical Engineering Research
    • /
    • v.56 no.6
    • /
    • pp.819-825
    • /
    • 2018
  • Porous nanofibers comprising hollow ${\alpha}-Fe_2O_3$ nanospheres were prepared by applying both template method and Kirkendall diffusion effect to electrospinning process. During heat-treatment processes, the solid Fe nano-metals formed by initial heat-treatment in the carbon matrix were converted into the hollow structured ${\alpha}-Fe_2O_3$ nanospheres. In particular, PS nanobeads added in the spinning solution were decomposed and formed numerous channels in the composite, which served as a good pathway for Kirkendall diffusion gas. The resulting porous nanofibers comprising hollow ${\alpha}-Fe_2O_3$ nanospheres were applied as an anode material for lithium-ion batteries. The discharge capacities of the nanofibers for the 30th cycle at a high current density of $1.0A\;g^{-1}$ was $776mA\;h\;g^{-1}$. The good lithium ion storage property was attributed to the synergetic effects of the hollow ${\alpha}-Fe_2O_3$ nanospheres and the interstitial nanovoids between the nanospheres. The synthetic method proposed in this study could be applied to the preparation of porous nanofibers comprising hollow nanospheres with various composition for various applications, including energy storage.

A study on the Optimization of Activated carbon Adsorbent Preparation condition and Evaluation of Application Supporting of K-Fe-Li ternary metal ions for Improving Adsorption Capacity of Hydrogen Sulfide (H2S) (황화수소(H2S) 흡착성능 증진을 위한 K-Fe-Li 3원계 금속이온물질이 담지된 활성탄 흡착제 제조조건 최적화 및 적용성 평가 연구)

  • Choi, Sung Yeol;Han, Dong hee;Kim, Sung Su
    • Clean Technology
    • /
    • v.25 no.3
    • /
    • pp.189-197
    • /
    • 2019
  • In this study an optimization of the preparation conditions of activated carbon with a ternary metal ion material to treat $H_2S$, which is classified as a representative odor substance, was carried out. For a metal ion material for enhancing the adsorption performance of hydrogen sulfide, performance enhancement was confirmed by combining Li and Fe or a ternary combination (K, Li, Fe) based on KI, which is a substance promoting hydrogen sulfide adsorption performance. Also, it was determined by XRD analysis that the reaction of each active substance with $H_2S$ was because of binding. The adsorption performance increased more than 3 times with heat treatment of the adsorbent with nitrogen compared with heat treatment with air. The maximum adsorption constant ($q_m$) value of the optimum adsorbent was 97.07, which is 6 times higher than that of the existing K-based impregnated activated carbon. It was confirmed that the objective adsorption amount ($0.3g\;g^{-1}$) was secured by an equilibrium between the mass transfer rate and adsorption rate. From the results, it was confirmed that the performance improvement was noticeable even when activated carbon with a reagent grade activated carbon particle size was modified. It was confirmed that the adsorption performance exists at high relative humidity levels of 60 and 100%, and the optimized preparation can be applied to a wet process such as a scrubber downstream.

The Effect on Attention of College Students by Epidermal Cooling in Posterior and Lateral of Upper Cervix (경추부 후면 및 측면 피부 냉각 작용이 대학생의 주의력에 미치는 영향)

  • Chang, Ji Hong
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
    • /
    • v.15 no.5
    • /
    • pp.328-334
    • /
    • 2022
  • The process that one may consciously focuses on necessary stimulation among tremendous amount of stimulation through human sensory systems is called attention in psychology. It is known that the attention can be affected by many factors such as room temperatures, humidity level, etc. In the field of sports science, ice packs are widely used for recovery from exercise fatigue providing fast heat transfer by conduction. However, the effect on attention by so-called iced-pack-cooling has not been tested. This research focuses on the attention levels when one is provided with a special cooling pad on their dorsal and lateral cervices. 40 subjects were divided into four groups and their attention level was evaluated based on the exposure conditions of combinations in reading and light walking with and without the cooling pad. The Frankfruter Aufmerksamkeits-Inventar, FAIR was used to evaluate the attention levels; the performance index, quality index, and continuity index consist of the FAIR test indicating the selectiveness of the attention, correctness of the attention, and maintaining term of the attention, respectively. Analysis of variance was carried out for those variables and post-hoc if applicable. When visual attention is constantly used for reading and studying, application of conductive heat transfer by the cooling pads is significantly helpful for improvement in selectiveness of the attention and maintaining terms of the attention levels. Also, light walking yielded improvement in selectiveness of the attention and maintaining terms of the attention levels; however one should presupposedly consider the loss of reading time.

Ablative Mechanism of SiC Coated Carbon/carbon Composites with Ratio of Oxygen to Fuel at Combusion Test (연소시험에서 산소와 연료 비에 따른 탄화규소로 코팅된 탄소/ 탄소 복합재의 삭마 메커니즘)

  • Zhang, Eun-Hee;Kim, Zeong-Baek;Joo, Hyeok-Jong
    • Applied Chemistry for Engineering
    • /
    • v.18 no.3
    • /
    • pp.227-233
    • /
    • 2007
  • Carbon/carbon (C/C) composites as unique materials possess exceptional thermal resistance with light weight, high stiffness, and strength even at high temperature. However, one serious obstacle for application of the C/C composites is their poor oxidation resistance in high temperature oxidizing environments. SiC coating has been employed to protect the composites from oxidation. This study explored combustion characteristics of 4-directional (4D) carbon/carbon composites using liquid fuel rocket engine to investigate ablative motion of the materials. C/C composites were made of coal tar pitch as a matrix precursor, and heat-treated at $2300^{\circ}C$. Throughout repeated densification process, the density of the material reached $1.903g/cm^3$. After machining 4D C/C composites, the nozzle surface was coated by a SiC layer by pack-cementation method to improve oxidation resistance. Erosion characteristics of SiC-coated C/C composites were measured as function of the ratio of oxygen to fuel. The morphological change of the composites after combustion test was investigated using SEM and erosion mechanism also was discussed.

Manufacture and Application of anhydrous calcium sulfate from flue gas desulfurization gypsum (排煙脫黃石膏로부터 無水石膏 製造 및 適用 特性)

  • Hyun, Jong-Yeong;Jeong, Soo-Bok;Chae, Young-Bae;Kim, Byung-Su
    • Resources Recycling
    • /
    • v.14 no.2
    • /
    • pp.10-18
    • /
    • 2005
  • The manufacture property of anhydrous calcium sulfate (anhydrite Ⅱ) from flue gas desulfurization (FGD) gypsum discharged from domestic thermoelectric power plants to apply as an auxiliary material of cement and concrete by high temperature treatment were investigated. The FGD gypsum was completely converted to anhydrite Ⅱ at the temperature of 700$^{\circ}C$ and the retention time of 1 hr. In the phase transformation process, particle size was also changed. The chemical composition, particle size and heat property of anhydrite Ⅱ made from the FGD gypsum were similar to them of natural gypsum. In the leaching test of sulfate ion (SO$_4^{2-}$) at the temperature of 90$^{\circ}C$ and the retention time of 1 hr, the amount of leached SO$_4^{2-}$ for the anhydrite Ⅱ that was sintered at 700$^{\circ}C$ for 1 hr was about 50 wt.% based on that of natural gypsum. In addition, the amount of leached SO$_4^{2-}$ for the anhydrite Ⅱ by adding the slaked lime of 3 wt.% decreased about 70 wt.% comparing with that of natural gypsum. In the application test, the compressive strength of cement and concrete manufactured by using the anhydrite Ⅱ as an auxiliary material were similar or superior compared with them of cement and concrete done by natural gypsum as an auxiliary material.

A Study on Volume Reduction of Waste Sludge by Aerobic Thermophilic Bacteria (호기성 호열미생물에 의한 하수슬러지 감량화 효율에 관한 연구)

  • Bae, Yoon-Sun;Kim, Soon-Young;Nam, Duck-Hyun;Park, Chul-Hwi;Kim, Jin-Su;Takada, Kazu
    • Journal of Korean Society of Water and Wastewater
    • /
    • v.19 no.4
    • /
    • pp.497-505
    • /
    • 2005
  • Domestic Sewage Treatment Plants are mostly based on biological treatment, in which large amounts of excess sludge are generated and occupy about 40 ~ 60% of the total sewage treatment costs. Several methods for sludge treatment has been so far reported as upgrading biodegradation of sludge; heat treatment, chemical treatment, including thermo-alkali and ozone, mechanical treatment including ultrasonic pulverization. But, it has a limitation in case of reducing the amount of excess sludge which are already producted. In this study, application of excess sludge reduction process using thermophilic aerobic bacteria for activated sludge was examined. The research was carried out two different stage. one for a biological wastewater treatment and the other for a thermophilic aerobic solubilization of the waste sludge. A portion of excess sludge from the wastewater treatment step was into the thermophilic aerobic sludge solubilization reactor, in which the injected sludge was solubilized by thermophilic aerobic bacteria. The solubilized sludge was returned to the aeration tank in the wastewater treatment step for its further degradation. Sludge solubilization reactor was operated at $63{\pm}2^{\circ}C$ with hydraulic retention time(HRT) of 1.5 ~ 1.7 day. Control group was operated with activated sludge process(AS) and experiment group was operated with three conditions(RUN 1, RUN 2, RUN3). RUN 1 was operated with AS without sludge solubilization reactor. RUN 2 were operated with AS with sludge solubilization reactor to examine correlation between sludge circulation ratio and sludge reduction ratio by setting up sludge circulation ratio to 3. RUN 3 was operated with sludge circulation ratio of 3 and MLSS concentration of 1,700~2,000mg/L to examine optimum operation condition. The quantity of excess sludge production was reduced sharply and in operation of RUN 3, sludge The quantity of excess sludge production was reduced sharply and in operation of RUN 3, sludge solubilization ratio and sludge reduction ratio were 53. 7%, 95.2% respectively. After steady state operation, average concentration of TBOD, SBOD, $TCOD_{Cr}$, $SCOD_{Cr}$, TSS, VSS, T-N, T-P of effluent were 4.5, 1.7, 27 .8, 13.8, 8.1, 6.2, 15.1, 1.8mg/L in the control group and were 5.6, 2.0, 28.6, 19.1, 9.7, 7.2, 16.1, 2.0mg/L in the experimental group respectively. They were appropriate to effluent standard of Sewage Treatment Plants.

Synthesis and Luminescence Characteristics of SrGa2S4:Eu Green Phosphor for Light Emitting Diodes by Solid-State Method (고상법을 이용한 LED용 SrGa2S4:Eu 녹색 형광체의 합성 및 발광특성)

  • Kim, Jae-Myung;Kim, Kyung-Nam;Park, Joung-Kyu;Kim, Chang-Hae;Jang, Ho-Gyeom
    • Journal of the Korean Chemical Society
    • /
    • v.48 no.4
    • /
    • pp.371-378
    • /
    • 2004
  • The $SrGa_2S_4:Eu^{2+}$ green emitting phosphor has been studied as a luminous device for CRT (Cathode Ray Tube) or FED (Field Emission Display) and EL (Electroluminescence). This phosphor, also, is under noticed for LED (Lighting Emitting Diode) phosphor, which makes use of excitation characteristics of long wavelength region. The $SrGa_2S_4:Eu^{2+}$ phosphor was prepared generally conventional synthesis method using flux. However, this method needs high heat-treated temperature, long reaction time, complex process and harmful $H_2S$or $CS_2$ gas. In this works, therefore, we have synthesized $SrGa_2S_4:Eu^{2+}$ using SrS, $Ga_2S_3$, and EuS as starting materials, and the mixture gas of 5% H2/95% N2 was used to avoid the $H_2S$or $CS_2$. We investigated the luminescence characteristic of $SrGa_2S_4:Eu^{2+}$ phosphor prepared in various synthesis conditions, performed post-treatment and sieving process for application to LED.

A study on the Practical Education in Fundamentals of Nursing (기본 간호학 실습교육의 현황)

  • Yoo Jae-Hee
    • Journal of Korean Academy of Fundamentals of Nursing
    • /
    • v.2 no.2
    • /
    • pp.199-211
    • /
    • 1995
  • This study analyzed the practical education in fundamentals of nursing, for the 36 nursing schools including 12 4-year nursing schools and 24 junior college nursing schools. This survey was done from september 5th to october 5th in 1995. The results of this study were as follows : 1. Required credit in fundamentals of nursing. 1) The highest incidence of the total required credit was 7 in 4-year nursing school and 9 in junior college. 2) For the lecture course credit, the large number of 4-year nursing school gave 5 credit lessons and 6 credits provided in junior nursing colleges. 3) For the credit of practical education the major portion of 4-year nursing school gave 2 credits instruction, however junior nursing school provided 3 credits. 2. Laboratory practice in fundamentals of nursing. In laboratory practice, the ratio of instructor and student was 1 : 20 in 83.4% of the 4-year nursing school and in 66.7% of the junior nursing school. 3. Contents and hours of fundamental nursing practice. 1) In the area of health assessment and nursing process, the large number of schools allocated following hours : 6 hours for vital signs, 4 hours for nursing process, 2 hours for recording but practice for physical examination and communication was done in few schools. 2) In the area of functional health pattern, the large number of schools allocated practice hours like followings : 2 hours for I/O, 2 hours for gavage feeding, 2 hours for elimination, 6 hours for catheterization, 6 hours for bed making, 2 hours for positioning, 6 hours for personal hygiene, 2 hours for R.O.M, 4 hours for moving turning lifting, 2 hours for inhalation and suction. But C.P.R and terminally ill patient care were taught in smaller number of schools. 3) In the area of special nursing measures, the major portion of nursing schools allocated hours like followings. It consisted of 6 hours for asepsis, 16-18 hours for medication, 2 hours for heat and cold application, 2 hours for wound care. 4) 22.2% of the nursing schools had total review practice time and 36.1% of the nursing schools had the students clinical practice. Based on above mentioned results, 4-year nursing school had faithful practical education of fundamental nursing than junior nursing school. But for the contents and allocated hours for practice education, junior nursing schools were much more contents and hours than 4 year school.

  • PDF