• Journal of Information Technology Services
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• v.10 no.2
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• pp.95-117
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• 2011

Today, IT governance has also become a subject of attention along with recent technologies such as ITSM (IT Service Management), PPM (Project Portfolio Management) and Compliance. At the national level, the market is fairly recent. and therefore, lacks detailed research in the field. Models specifically related to EIM has not yet been presented to this day, hence, firms that are considering EIM as a potential part of their information management system may fall into a state of disorder in the process of its implementation. To this end, this research attempts to construct an IT governance model for EIM based on existing models, surveys and interviews. In particular, E-discovery has been applied as means of protecting information assets and its use as evidence. In addition, by applying the research model to a particular global firm and then assessing its documentation management system, the overall feasibility of the research model has been tested.

• The Journal of Information Systems
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• v.3
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• pp.147-169
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• 1994

This paper present s a pattern generation scheme from financial charts. The patterns constitute knowledge which consists of patterns as the conditional part and the impact of the pattern as the conclusion part. The patterns in charts are represented in a syntactic approach. If the pattern elements and the impact of patterns are defined, the patterns are synthesized from simple to the more highly credible by evaluating each intermediate pattern from the instances. The overall process is divided into primitive discovery by Genetic Algorithms and pattern synthesis from the discovered primitives by the Syntactic Pattern-based Inductive Learning (SYNPLE) algorithm which we have developed. We have applied the scheme to a chart : the trend lines of stock price in daily base. The scheme can generate very credible patterns from training data sets.

• YAKHAK HOEJI
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• v.59 no.4
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• pp.151-157
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• 2015

The purpose of this study is to demonstrate how lead compounds are best optimized with the application of in silico QSAR and PBPK modeling at the early drug discovery stage. Several predictive QSAR models such as $IC_{50}$ potency model, intrinsic clearance model and brain penetration model were built and applied to a set of virtually synthesized library of the BACE1 inhibitors. Selected candidate compounds were also applied to the PBPK modeling for comparison between the predicted animal pharmacokinetic parameters and the observed ones in vivo. This novel lead optimization strategy using QSAR and PBPK modelings could be helpful to expedite the drug discovery process.

• Journal of Korean Society of Rural Planning
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• v.19 no.4
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• pp.161-175
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• 2013

The paradigm of agricultural and rural policies has shifted from food production and profitability to the competitiveness of rural areas through the discovery, grants and use of the agricultural and rural resources' potential value. This study aims to discover the value of the agriculture and rural resources and intend to offer the method for discovering resources and its value as the agricultural heritage. To this end, the functions and values of the agricultural and rural resource, the criteria and procedure of Globally and Nationally Important Agricultural Heritage System which is leading institutions were investigated. The policy implications were proposed in the process and series of steps of discovery and evaluation of the pluralistic value of the agriculture and rural resources and agricultural heritage designation and management.

• Journal for History of Mathematics
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• v.16 no.2
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• pp.55-70
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• 2003

This study investigated tile intuitive level of justification in geometry, as the former step to the aximatization, with concrete examples. First, we analyze limitations that the axiomatic method has in tile context of discovery and the educational situation. This limitations can be supplemented by the proper use of the intuitive method. Then, using the histo-genetic analysis, this study shows the process of the development of geometrical thought consists of experimental, intuitive, and axiomatic steps. The intuitive method of proof which is free from the rigorous axiom has an advantage that can include the context of discovery. Finally, this paper presents the issue of intuitive proving that the three angles of an arbitrary triangle amount to 180$^{\circ}$, as an example of the local systematization.

• Journal of Information Technology Applications and Management
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• v.13 no.4
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• pp.121-140
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• 2006

UDDI (Universal Discovery Description and Integration) Registry is used for Web Services registration and search. UDDI offers the search result to the keyword-based query. UDDI supports WSDL registration but it does not supports WSDL search. So it is required that contents based search and ranking using name and description in UDDI registration information and WSDL. This paper proposes a retrieval engine considering contents of services registered in the UDDI and WSDL. It uses Vector Space Model for similarity comparison between contents of those. UDDI registry information hierarchy and WSDL hierarchy are considered during searching process. This engine suppports two discovery methods. One is Keyword-based search and the other is template-based search supporting ranking for user's query. Template-based search offers how service interfaces correspond to the query for WSDL documents. Proposed retrieval engine can offer search result more accurately than one which UDDI offers and it can retrieve WSDL which is registered in UDDI in detail.

• IE interfaces
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• v.14 no.2
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• pp.164-171
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• 2001

We suggest a Business Performance Information System with Knowledge Discovery in Databases(KDD) as a key component of integrated information and knowledge management system. The proposed system measures business performance by considering both VA(Value-Added), which represents stakeholder's point of view and EVA(Economic Value-Added), which represents shareholder's point of view. In modeling of Business Performance Information System, we apply the following KDD processes : Data Warehouse for consistent management of a performance data, On-Line Analytic Processing(OLAP) for multidimensional analysis, Genetic Algorithms for exploring and finding dominant managing factors and Analytic Hierarchy Process(AHP) for applying expert's knowledge and experience. To demonstrate the performance of the system, we conducted a case study using financial data of Korean automobile industry over 16 years from 1981 to 1996, which is taken from database of KISFAS(Korea Investors Services Financial Analysis System).

• 한국생물공학회:학술대회논문집
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• 2000.11a
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• pp.119-122
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• 2000

Biological science is being revolutionized by the availability of much sequence information from many genome project With the advanced technology at hand, main trend in biological research is rapidly changing from a structural DNA analysis to understanding cellular function of the DNA sequences. Combined with mechanics, computer, bioinformatics and other advanced technologies, DNA chip technology provides numerous applications because of its robustness, accuracy, and automation. DNA chip is expected to become an indispensable tool in fields of biology, biotechnology, drug discovery, and other application areas. DNA chip can be used for mutation and polymorphism detection, gene expression monitoring and phenotypic analysis as well. If DNA chip is used for the development of pharmaceutical products, it can considerably reduce the cost and time for the entire process of drug discovery and development, and can also contribute in developing personal drugs.

• Journal of Information Processing Systems
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• v.13 no.6
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• pp.1527-1543
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• 2017

MiRNA is a biological short sequence, which plays a crucial role in almost all important biological process. MiRNA patterns are common sequence segments of multiple mature miRNA sequences, and they are of significance in identifying miRNAs due to the functional implication in miRNA patterns. In the proposed approach, the primary miRNA patterns are produced from sequence alignment, and they are then cut into short segment miRNA patterns. From the segment miRNA patterns, the candidate miRNA patterns are selected based on estimated probability, and from which, the potential miRNA patterns are further selected according to the classification performance between authentic and artificial miRNA sequences. Three parameters are suggested that bi-nucleotides are employed to compute the estimated probability of segment miRNA patterns, and top 1% segment miRNA patterns of length four in the order of estimated probabilities are selected as potential miRNA patterns.

• Journal of The Korean Association For Science Education
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• v.33 no.1
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• pp.30-45
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• 2013

In this study, we developed a model for analyzing scientists' creative thinking processes, and analyzed Archimedes' thinking process in solving the golden crown problem. As results show, scientists' complex problem solving processes could be represented as a repeating circular model, and the fusion of processes of diverse thinking required for scientists' creativity could be analyzed from the case. Also in this study, we represented the role of experiments in scientists' creative discovery, and investigated the reasons for the difference between the viewpoints of textbooks and historic facts. We found the importance of abductive reasoning and advance knowledge in creative thinking. Archimedes solved the golden crown problem creatively by crossing the scientific thought of dynamics and the daily thought of baths. In this process, abductive reasoning and advance knowledge played an important role. Besides Archimedes' case, if we would reconstruct the creative discovery processes of diverse scientists' in textbooks, students could raise their creative thinking ability by experiencing these processes as educational steps.