• 한국환경농학회지
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• 제19권2호
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• pp.147-153
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• 2000

흡연은 직접 또는 environmental tobacco smoke를 통하여 많은 위해성 물질을 인체에 유입시킨다. 이러한 위해 물질중 니코틴을 인체내의 대사에 따라서 암을 유발시키는 물질로 전이되기도 한다. 니코틴의 대사산물로 대표적인 발암물질인 nitrosamine-4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone (NNK)가 있다. 많은 연구는 녹차의 추출물이 암을 예방하는데 탁월한 효능이 있음을 보고하고 있다. 그러나, 녹차의 암예방 효과에 대한 기작은 거의 알려져 있지 않다. 최근의 보고는 니코틴의 주요대사 산물인 코니틴이 안정한 물질임과 동시에 NNK의 활성 및 형성을 억제하는 것으로 알려져 있다. 본 연구는 세포내의 니코틴의 대사에 있어, 코티닌으로의 전이도에 녹차의 추출물이 미치는 영향에 대하여 연구하였다. 녹차의 추출물은 시험관에서 직접 혼합한 경우와 세포주를 이용한 실험에서, 니코틴이 코티닌으로 전이하는 데 긍정적 영향을 주었다. 이 결과는 녹차의 성분 중에 니코틴의 여러 대사경로중에서 코티닌의 대사를 촉진하는 물질이 함유되어 있음을 의미한다. 이 결과는 아울러, 녹차의 암 예방의 가능성에 대하여 설명할 수 있는 기전을 제시한다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5715-5719
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• 2015

Background: Breast cancer is the most common malignancy of women in the world. The disease is caused by infectious and non-infectious, environmental and lifestyle factors. Tobacco smoke has been one of the most widely studied environmental factors wiith possible relevance to breast cancer. The purpose of this study was to assess the impact of tobacco smoking in breast cancer patients in a hospital based cohort and to establish prognostic implications if any. Materials and Methods: A retrospective audit of 100 women with pathological diagnosis of invasive breast cancer was included in this study. The verbal questionnaire elicited information on current and previous history of exposure to smoking in addition to active smoking. All analyses were adjusted for potential confounders, including stage at presentation, alcohol intake, hormonal replacement therapy, oral contraceptive intake, obesity and menopausal status. Results: The mean age at presentation of breast cancer was $51.4{\pm}10.86$ years. Mean age of presentation was $53.1{\pm}11.5$ and $45.7{\pm}11.9$ years in never smokers and passive smokers, respectively. Age at presentation varied widely in patients exposed to tobacco smoke for >10 years in childhood from $40.3{\pm}12.0$ years to $47.7{\pm}13.9$ in patients exposed for > 20years as adults. Among passive smokers, 60.9% were premenopausal and 39.1% of patients were postmenopausal. In never smokers, 71.4% were post menopausal. Expression of receptors in non-smokers vs passive smokers was comparable with no significant differences. Metastatic potential in lung parenchyma was slightlyelevated in passive smokers as compared to never smokers although statistically non-significant. Conclusions: An inverse relationship exists between the intensity and duration of smoking and the age at presentation and poor prognostic factors. The results strongly suggest efforts should be taken to prevent smoking, encourage quitting and restrict exposure to second hand smoke in India.

• 한국화재조사학회지
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• 제6권1호
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• pp.49-66
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• 2005

이 연구는 아트리움의 방화안전성 고찰 및 적정한 방화 장치의 기준제시를 초점으로 하고 있다. 주요 내용으로는 아트리움 공간의 일반적 고찰, 아트리움 건물의 실례와 방재상의 문제점을 알아보았고, 현재 우리나라 아트리움 공간에 설치되어 있는 방화설비 등을 조사하여 외국의 여러 기준과 비교함으로써 드러난 문제점 및 취약요인을 바탕으로 아트리움 설계 시 특히 유의하여야 할 사항에 대하여 탐구하였다. 여기서 주장한 아트리움 공간의 효과적인 소화설비기준은 다음과 같다. 1 제연 설비는 비상동력이 부설된 기계제연에 의한 강제배연이 알맞다. 2 아트리움 공간과 연결된 다른 부분에서 공기의 유입이 되지 않도록 연결된 부분(1층 제외)을 화재 시 지동으로 구획되는 가동벽 셔터 방화문을 설치한다. 3. 분리형 적외선 감지기를 아트리움 바닥으로부터 7~8m 높이에 설치하여 조기에 화재를 감지하도록 한다. 4. 천장이 20m이하인 아트리움의 경우 아트리움 천장에 개방형 스프링클러헤드를 설치하고 일제개방밸브를 작동시켜 해당구역에 소화수를 집중 방출하게 하며, 천장이 20m이상인 아트리움의 경우 측벽형 헤드를 저층부의 벽체에 설치하여 수평분출로 소화한다. 5. 피난 계단으로의 이동은 아트리움 공간을 지나지 않고 할 수 있도록 설계되어야한다. 6. 일부부재의 내력저하가 생겨도 전체의 붕괴에는 이르지 않게, 아트리움의 철골의 트러스재는 내화재로 보호한다.

• 터널과지하공간
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• 제16권1호
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• pp.85-94
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• 2006

본 연구에서는 장대 터널 화재시 발생되는 역기류를 제압하는 최적의 임계속도를 결정하기 위하여 제연설비를 가동시키는데 소요되는 시간, 피난자들의 대피시간 등에 대한 연구 자료들을 취합, 분석하였고, 이를 토대로 화재 시나리오를 설정하여 축소 모형실험을 실시하였다. 비상 환기시스템 가동시점을 분석한 결과, 화재 발생후 약 240초(약 4분)후 비상 환기시스템이 가동하게 되며, 제연팬 가동 후 4분 이내에 역기류를 제어할 수 있는 임계속도를 확보하는 것이 실제 터널에 적합한 시간 시나리오였다. 화재지점 주변의 역기류 분포를 분석하기위해 Froude 상사이론에 기초한 아크릴 재질의 축소비 1/50의 모형(직경 : 0.2m, 연장 : 20 m)을 제작하였고, Tetzner 식의 보정계수$(\beta)$를 변화시키며 화재지점 주변의 CO농도를 측정한 결과, 보정계수가 0.5인 경우에 피난허용시간 기준에 적합한 제연효과를 나타내었다.

• 한국인터넷방송통신학회논문지
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• 제19권6호
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• pp.191-196
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• 2019

도시철도 시설물의 경우, 대중교통의 특성상 전력공급이 차단되면 혼란이 발생하므로 통신설비, 방재설비 및 승차장 안전문 등이 안전한 승객의 이동을 위해 전원공급이 유지되어야 한다. 또한, 도시철도 운행노선에는 다수의 전동차가 운행 중이므로 운행 간격과 시설복구 시간을 고려하면 승차장 안전문은 최소 30분 이상, 통신설비 및 방재설비는 1시간 이상의 설비가동이 요구된다. 따라서 도시철도 구간의 역사나 차량화재발생 시 화재로 인한 추가확산을 막기 위해 주요전력이 차단되므로 유도등 및 배연설비의 안정적 동작 유지를 위해 비상 전원공급이 필수적이다. 최근에는 비상시 정전을 방지하는 UPS (uninterruptible power supply, 무정전 전원공급장치) 기능과 가격이 저렴한 야간 시간대에 전기를 저장하였다가 주간 피크시간대에 사용할 수 있도록 하여 전기요금을 절감해주는 ESS 기능을 합친 비상발전용 UPS 기능을 갖춘 복합형 전력저장시스템을 개발하는 추세이다.

• 한국학교보건학회지
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• 제19권2호
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• pp.75-88
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• 2006

Purpose : This study are the secondary data of Global Youth Tobacco Survey(GYTS) developed by the WHO and United State Center for Disease Control(CDC) and Prevention to trace tobacco use among youth in youth in countries across the world. This study was carried out to serve for a basis for antismoking campaigns and to prevent adolescents from smoking by analyzing the smoking by analyzing the smoking realities factors. Methods : This study is a cross-sectional school-based survey, which employed a two-stage cluster sample design to produce a nationally representative sample of middle school students aged 13 to 15 years olds. Seventy-five schools were selected. All schools containing grade 1, 2 and 3 that contained 40 or students were included in the sampling frame. Results : The results of this study were as follows ; 1. The proportion of smoking students in middle school was 6.4% and the rate of smoking in male students(7.4%) was higher than it of in female students(5.5%). 2. 26.5% of all respondent had a experience to try smoke and the results showed that the rate of trying smoking in male students was increased by grade more than female students. 3. According to test of significance in regression analysis, the independent variables such as sex, school grade, smoking parents, friends distinction, pocket money and others showed statistical significance. 4. There was a statistical significance between smokers and nonsmokers in proportion to the completing the preventive education for nonsmoking(p=0.0023) and the acquirement of knowledge on smoking(p<.0001). 5. Finally there was a statistical significance between the exposure to anti-smoking campaign(p=0.0053) and tobacco advertisement in the mass media and the smoking(p=0.0036). Conclusion : All things considered, the health education for tobacco control in school need to be developed from an elementary school. I suggest that prevent smoking program in school need to be revitalized and be made more accessible for everyone who wish to quit. And the government should develop the regulation on total banning promoting cigarette advertising and smoking scene in the movie for young people.

• 한국전자통신학회논문지
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• 제16권6호
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• pp.1019-1028
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• 2021

가스 센서, 조도 센서, 온도 센서, 아두이노 우노, 블루투스 모듈을 이용하여 화재 발생 시 비상구 위치를 신속하게 파악하기 위해 비상구 유도등을 설계하고 제작하였다. 본 연구는 화재 발생 시 가스 센서와 온도 센서를 이용하여 높은 온도와 연기를 감지하였을 때 시인성을 좋게 하기 위하여 조도 값이 낮을수록 적색 화살표, 조도 값이 높을수록 녹색 화살표가 나오도록 설계하였다. 또한 통신 모듈을 이용한 경보음과 문자전송 알고리즘을 응용하여 174Hz의 경보음과 화재 장소를 알리는 문자메시지를 소방서로 송신하는 기능을 추가하여 보다 큰 화재를 예방할 수 있게 설계되었다.

• 설비공학논문집
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• 제27권1호
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• pp.24-30
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• 2015

The fire on a high-rise building would possibly cause fatalities because of ineffective egress due to extended evacuation distance in huge building structure, coupled with dense population, thus requiring secured optimal evacuation method and space. The restroom located in the living space is considered to be useful refuge space which is built with wet pipe and noncombustible materials. This study aimed to develop a system that would make use of the existing restroom as a fire refuge space. Ventilation duct were installed to discharge odor during normal conditions. We could serve the air supply duct to also raise the air pressure in the restroom so as to prevent the toxic gas from gapping around the restroom. The nozzle for the water screen would be installed in restroom door facing the living room to form the water screen which would protect the door. This study is intended to replace the existing refuge space with the restroom in such a way as described above.

• 한국치위생학회지
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• 제19권6호
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• pp.951-961
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• 2019

Objectives: This study aims to evaluate how the amount and duration of smoking effects the bleeding and pain of gingival among adolescents in Korea while also taking into consideration the impact of drinking. Methods: Data were utilized from a web-based survey of youth health behaviors conducted by the Korean Center for Disease Control and Prevention in 2016. The subjects of the study included 65,528 adolescents from middle and high schools. As dependent variables, bleeding and pain of gingival were used. Data were analyzed using the SPSS Version 20.0 program. Results: After adjusting for the general characteristics and oral health behaviors of the subjects, in the long-term, the ≥0.52 PY group (heavy smoker) experienced 1.28 times higher bleeding and pain of gingival than the <0.52 PY group (light smoker) among adolescents who smoke and drink at the same time. Adolescents who smoked without drinking did not show any difference on bleeding and pain of gingival according to the amount of smoking in the short- and long-term. However, the findings reveal that there was a difference on bleeding and pain of gingival according to tooth brushing frequency. Conclusions: In order to promote the periodontal health of adolescents, it is argued that programs and projects should be implemented to prevent, educate, and control simultaneous behaviors of smoking and drinking.

• Journal of Nutrition and Health
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• 제35권7호
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• pp.763-770
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• 2002

This study was carried out to see dietary intakes of patients with coronary heart disease since we don't understand their dietary patterns even though the mortality and prevalence rate of coronary hear disease are increasing in this country. We studied 75 coronary heart disease patients and 150 randomly selected controls, matched for age, sex, height and weight, in a population based study. All subjects completed a questionnaire that included disease history, diagnosis time, current treatment, etc., a 24 hour dietary recall, and measurement of height and weight. Compared to controls, patients had less likely to drink alcohol and smoke cigarette (p＜0.05). The energy intake of patients was significantly lower than that of controls, but the intakes of fiber, $\beta$-carotene, sodium, folate, vitamin C, potassium in male patients and those of vitamin C and sodium in female patients were significantly higher than those of controls (p＜0.05). Mean adequacy ratio and dietary variety score of patients were also higher than those of controls (p＜0.05). Patient group's consumed less cereals than controls, but more vegetables, milk products, and nuts in male patients and fruits, beans and seasonings in female patients compared to controls'. There were not significant differences of lipid compositions between two groups, except linolenic acid. These data suggest that patients with coronary heart disease in Korea had better dietary nutrient intakes compared to healthy controls, which might be helpful to prevent recurrence of coronary heart disease.