• Journal of the Korean Magnetic Resonance Society
• /
• v.26 no.2
• /
• pp.21-23
• /
• 2022

High-pressure (HP) NMR is a powerful method to elucidate various structural features of amyloidogenic proteins. Following the previous mini-review recapitulating the HP-NMR application for amyloid-β peptides of the last issue [J. H. Kim, J. Kor. Mag. Reson. Soc. 26, 17 (2022)], the recent advancements in the HP NMR application for α-synuclein (α-Syn) are briefly summarized and discussed here. Although α-Syn is a well-known intrinsically disordered protein (IDP), several studies have shown that it can also exhibit heterogeneous yet partially folded conformations, which may correlate with its amyloid-forming propensity. HP NMR has been a valuable tool for investigating the dynamic and transient structural features of α-Syn and has provided unique insights to appreciate its aggregation-prone characters.

• Journal of the Korean Magnetic Resonance Society
• /
• v.26 no.1
• /
• pp.17-20
• /
• 2022

High-pressure (HP) NMR is a versatile tool to investigate diverse features of proteins. This technique has been particularly powerful to elucidate structural dynamics that only populates sufficiently in a pressurized condition. Amyloidogenic proteins, which are prone to aggregate and form amyloid fibrils, often maintains highly dynamic states in its native or aggregation-prone states, and HP NMR contributed much to advance our understandings of the dynamic behaviors of amyloidogenic proteins and the molecular mechanisms of their aggregation. In this mini review, we therefore summarize recent HP NMR studies on amyloid-beta (Aβ), the representative amyloidogenic intrinsically disordered protein (IDP).

• JSTS:Journal of Semiconductor Technology and Science
• /
• v.13 no.4
• /
• pp.355-360
• /
• 2013

A wireless intraocular (IOP) pressure sensor based on micro electro mechanical system (MEMS) technology is proposed. The proposed IOP sensor uses variable inductance according to the external pressure. The proposed sensor is composed of two flexible membranes: a ferrite bottom part, an inductor, and a capacitor. The inductance of the sensor varies according to the external pressure. The resonance frequency of the sensor is also varied, and this frequency is detected using an external coil. The external coil is designed with an FR-4 printed circuit board. The feasibility of the proposed sensor structure using variable inductance to detect the external pressure is successfully demonstrated.

• Journal of Institute of Control, Robotics and Systems
• /
• v.21 no.7
• /
• pp.609-614
• /
• 2015

Implanted telemetry systems provide the ability to monitor different species of animals while they move within their cages. Species monitored include mice, rats, rabbits, dogs, pigs, primates, sheep, horses, cattle, and others. A miniature transmitter implanted in each animal measures one or more parameters. Parameters measured include arterial pressure, intra-pleural pressure, left ventricular pressure, intra-ocular pressure, bladder pressure, ECG, EMG, EEG, EOG, temperature, activity, and other parameters and transmits the data via radio frequency signals to a nearby receiver. Every conventional dedicated transmitter contains one or more sensors, cpu and battery. Due to the expected life of the battery, the measuring time is limited. To overcome these problems, electromagnetic inductive coupling based wireless power transmission technology using multiple transmit coils were proposed, with each coil having a different active area driven by the coil driver. In this research, a parallel resonance based coil driver and serial resonance based coil driver are proposed. From the experiments we see that the parallel coil driver shows better performance under a low impedance and multiple coils configuration. However, the serial coil driver is more efficient for high impedance transmit coils.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2004.11a
• /
• pp.178-183
• /
• 2004

This paper presents phenomena of vibration and noise due to acoustic resonance in tube bank of a large fossil power plant. The phenomena of acoustic resonance may arise when the vortex shedding frequency coincides with the acoustic natural frequency. In this system dominant frequency of vibration and noise was 37.5Hz. The $3^{rd}$ acoustic natural frequency calculated was 37.2 Hz. When the difference of vortex shedding frequency and acoustic natural frequency is within ${\pm}20%$, acoustic resonance could occur. If system is the state of acoustic resonance, vibration and noise become large. In order to prevent acoustic resonance, anti-noise baffle should be installed in the tube bank. In the case of installing baffle, we should consider the number of baffle and the effect of acoustic mode due to baffle extension length. To do this, we did acoustic mode analysis. After installing anti-noise baffle, acoustic resonance was disappeared and vibration magnitude and noise level was reduced dramatically.

• Proceedings of the Korean Society of Propulsion Engineers Conference
• /
• 2012.05a
• /
• pp.230-237
• /
• 2012

The ultrasonic resonance method was applied to detect the disbond interface and empty layer between steel and FRP of the exit cone. The ultrasonic resonance method can easily detect the disbond interface and empty layer by amplifying the ultrasonic signal, but pulse echo method is difficult to distinguish adhesive interface from disbond interface or empty layer. The resonance frequency was predicted using the pressure reflection coefficient of 3-layered medium, and measured from ultrasonic signal of the test block using Fast Fourier Transform. The ultrasonic resonance proved that the predicted resonance frequency was in good agreement with the measured resonance frequency.

• Journal of the Semiconductor & Display Technology
• /
• v.4 no.2 s.11
• /
• pp.1-5
• /
• 2005

Electon spin resonance measurements have been performed on the Mg-doped wurtzite GaN thin films grown on sapphire substrates by low-pressure metal-organic chemical vapor deposition. The sample set included films as-grown with the regular Mg doped and Mg delta doped samples and the corresponding annealed ones. The resonance signal has been observed from the annealed Mg delta-doped sample with the Lande g value of 2.029. This indicates that the singlet resonance signal originates from the neutral Mg acceptor located at 0.24 eV above the valence band edge and 0.13 eV above the Fermi level because of the nuclear hyperfine spin 1=0 of Mg and the larger value than the free electron g=2.0023.

• Transactions of the Korean Society for Noise and Vibration Engineering
• /
• v.26 no.1
• /
• pp.13-19
• /
• 2016

The flow-excited Helmholtz resonance phenomenon was investigated numerically using Reynolds averaged Navier-Stokes approach. The fundamental cause of the Helmholtz resonance phenomenon is known as shedding of a single discrete vortex from orifice edge that travels during one period of the oscillation. In this study, serrated deflector, which is biomimetic design of the owl's feather, is used to split a single vortex into small vortices. Rectangular deflector and serrated deflector are compared with numerical results of pressure and streamline inside the cavity. Consequently, the serration breaks the shedding period of vortex core and eliminates the resonance. Also, it changes the flow pattern in according to the location of different serration height. By making inflows and outflows occur simultaneously in spanwise direction in the cavity, the period of Helmholtz resonance disappears. Comparing between rectangular deflector and serrated deflector, the serrated deflector can deal with the Helmholtz resonance more effectively.

• Korean Journal of Materials Research
• /
• v.20 no.12
• /
• pp.640-644
• /
• 2010

Information technology devices, such as cellular phones, MP3s and so on, due to restrictions of space, require thin and small micro-speakers to generate sound. The reduction of the size of micro-speakers has resulted in the decrease of sound quality, due to such factors as frequency range and sound pressure level. In this study, the acoustical properties of oval microspeakers has been studied as a function of pattern shape on the diaphragm. The other conditions of micro-speakers, except for the pattern, was not changed. When the pattern is present on the diaphragm and the shape of pattern was a whirlwind, the resonance frequency was reduced due to the decrease of tensile strength of diaphragm. The patterns presented in the semi-minor axis of diaphragm did not effect a change of resonance frequency. However, increasing the number of patterns in the semimajor axis of diaphragm became a reason for the decrease of resonance frequency on edge side. When the depth of pattern on edge side was increased, the resonance frequency was decreased due to reduction of geometrical stiffness. If the height of edge and dome were increased, the resonance frequency and geometrical stiffness rapidly increased. After reaching the maximum values, they began to decrease with the continuous increase of height.

• Proceedings of the Korean Nuclear Society Conference
• /
• 2002.10a
• /
• pp.306.1-306
• /
• 2002