• Title/Summary/Keyword: Pressure Key

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Effects of Central Interleukin-1 on the Cardiovascular Response in Hemorrhaged Rats

  • Kang, Joon-Ho;Jang, Jae-Hee;Ahn, Dong-Kuk;Park, Jae-Sik
    • The Korean Journal of Physiology and Pharmacology
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    • v.8 no.2
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    • pp.89-94
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    • 2004
  • The arterial pressure is regulated by the nervous and humoral mechanisms. The neuronal regulation is mostly carried out by the autonomic nervous system through the rostral ventrolateral medulla (RVLM), a key area for the cardiovascular regulation, and the humoral regulation is mediated by a number of substances, including the angiotensin (Ang) II and vasopressin. Recent studies suggest that central interleukin-1 (IL-1) activates the sympathetic nervous system and produces hypertension. The present study was undertaken to elucidate whether IL-1 and Ang II interact in the regulation of cardiovascular responses to the stress of hemorrhage. Thus, Sprague-Dawley rats were anesthetized and both femoral arteries were cannulated for direct measurement of arterial pressure and heart rate (HR) and for inducing hemorrhage. A guide cannula was placed into the lateral ventricle for injection of IL-1 $(0.1,\;1,\;10,\;20\;ng/2\;{\mu}l)$ or Ang II $(600\;ng/10\;{\mu}l)$. A glass microelectrode was inserted into the RVLM to record the single unit spike potential. Barosensitive neurons were identified by an increased number of single unit spikes in RVLM following intravenous injection of nitroprusside. I.c.v. $IL-1\;{\beta}$ increased mean arterial pressure (MAP) in a dose-dependent fashion, but HR in a dose-independent pattern. The baroreceptor reflex sensitivity was not affected by i.c.v. $IL-1\;{\beta}$. Both i.c.v. $IL-1\;{\alpha}\;and\;{\beta}$ produced similar increase in MAP and HR. When hemorrhage was induced after i.c.v. injection of $IL-1\;{\beta}$, the magnitude of MAP fall was not different from the control. The $IL-1\;{\beta}$ group showed a smaller decrease in HR and a lower spike potential count in RVLM than the control. MAP fall in response to hemorrhage after i.c.v. injection of Ang II was not different from the control. When both IL-1 and Ang II were simultaneously injected i.c.v., however, MAP fall was significantly smaller than the control, and HR was increased rather than decreased. These data suggest that IL-1, a defense immune mediator, manifests a hypertensive action in the central nervous system and attenuates the hypotensive response to hemorrhage by interaction with Ang II.

Evaluation of Shear Strength by Direction of Wood Grain for Korean Pine Using PRF Adhesive (페놀레조시놀공축합수지로 접착된 국산 잣나무의 목리방향별 전단성능평가)

  • Park, Sun-Hyang;Kim, Kwang-Mo;Pang, Sung-Jun;Kong, Jin Hyuk;Lee, Sang-Joon
    • Journal of the Korean Wood Science and Technology
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    • v.45 no.3
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    • pp.243-249
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    • 2017
  • This study was performed to find out the optimum adhesive conditions on manufacturing a cross-laminated timber (hereinafter CLT) with using domestic Korean Pine (Pinus koraiensis). The adhesive conditions including a applied amount of the glue and a Pressure are the one of the most important key factors on establishing CLT production process. The shear strength was examined with differing the adhesive conditions while using Phenol Resorcinol Formaldehyde Resin Adhesive (PRF resin). The optimum adhesive conditions was confirmed to be: glue spread of $250g/m^2$ and Pressure of 0.8 MPa respectively. The grain directions of glued specimens were also considered, perpendicularly bonded and parallelly bonded groups. Shear strength of the former group showed lower values than the latter group which is considered to be the effect of a rolling shear. Meanwhile the shear strength of both group satisfied the Korean Standard (KS F 3021) and the European Standard (EN 14080 and EN 16351). The results derived from this study can be used as the basic data for manufacturing the CLT with domestic Korean Pine. And additional researches for the other species including domestic Korean Larch and Pitch Pine is also now being performed.

Development of Integrated Type Main Frame and Downhole Sonde Apparatus for Hydraulic Packer Testing in Seabed Rock under High Water Pressure (고수압 해저지반 수리특성 조사용 일체형 메인 프레임과 공내 측정장치 개발)

  • Bae, SeongHo;Kim, Jangsoon;Jeon, Seokwon;Kim, Hagsoo
    • Tunnel and Underground Space
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    • v.28 no.3
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    • pp.258-276
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    • 2018
  • The accurate and quantitative ground information on the hydraulic conductivity characteristics of rock mass is one of the key factors for evaluation of the hydro-geological behaviour of rock mass around an excavated opening under high water pressure. For tunnel and rock structures in seabed, where the sea acts as an infinite source of water, its importance become greater with increasing construction depth below sea level. In this study, to improve the problems related with poor system configuration and incorrect data acquisition of previous hydraulic packer testing equipment, we newly developed an integrated main frame and 30 bar level waterproof downhole sonde apparatus, which were optimized for deep hydraulic packer test in seabed rock mass. Integration of individual test equipment into one frame allows safe and efficient field testing work on a narrow offshore drilling platform. For the integrated type main frame, it is possible to make precise stepwise control of downhole net injection pressure at intervals of $2.0kg_f/cm^2$ or less with dual hydraulic oil volume controller. To ensure the system performance and the operational stability of the prototype mainframe and downhole sonde apparatus, the field feasibility tests were completed in two research boreholes, and using the developed apparatus, the REV(Representative Elementary Volume) scale deep hydraulic packer tests were successfully carried out at a borehole located in the basalt region, Jeju. In this paper, the characteristics of the new testing apparatus are briefly introduced and also some results from the laboratory and in-situ performance tests are shown.

Techno-economic Comparison of Absorption and Adsorption Processes for Carbon Monoxide (CO) Separation from Linze-Donawitz Gas (LDG) (Linze-Donawitz 가스로부터 일산화탄소(CO) 분리를 위한 흡수 및 흡착공정에 대한 기술경제성 비교)

  • Lim, Young-Il;Choi, Jinsoon;Moon, Hung-Man;Kim, Gook-Hee
    • Korean Chemical Engineering Research
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    • v.54 no.3
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    • pp.320-331
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    • 2016
  • Linze-Donawitz gas (LDG) adjunctively produced in the steel mill contains over 60% of CO. Two processes that recover high purity CO from LDG were considered: COSORB and CO-Pressure swing adsorption (PSA). This study aimed to decide which one is more economically feasible than the other by techno-economic analysis (TEA). From the technical point of view of TEA, the process flow diagram (PFD) was constructed, the mass and energy balances were calculated, and the equipment type and size were determined in order to estimate the total capital investment (TCI) and the total production cost (TPC). From the economic point of view of TEA, economic performance such as return on investment (ROI) and payback period (PBP) was evaluated, and the sensitivity analysis was carried out to identify key factors influencing ROI and PBP. It was found that CO-PSA is more economically feasible due to higher ROI and lower PBP. The CO price highly influenced ROI and PBP.

Robust Design for Showerhead Thermal Deformation

  • Gong, Dae-Wi;Kim, Ho-Jun;Lee, Seung-Mu;Won, Je-Hyeong
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.150.1-150.1
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    • 2014
  • Showerhead is used as a main part in the semiconductor equipment. The face plate flatness should remain constant and the cleaning performance must be gained to keep the uniformity level of etching or deposition in chemical vapor deposition process. High operating temperature or long period of thermal loading could lead the showerhead to be deformed thermally. In some case, the thermal deformation appears very sensitive to showerhead performance. This paper describes the methods for robust design using computational fluid dynamics. To reveal the influence of the post distribution on flow pattern in the showerhead cavity, numerical simulation was performed for several post distributions. The flow structure appears similar to an impinging flow near a centered baffle in showerhead cavity. We took the structure as an index to estimate diffusion path. A robust design to reduce the thermal deformation of showerhead can be achieved using post number increase without ill effect on flow. To prevent the showerhead deformation by heat loading, its face plate thickness was determined additionally using numerical simulation. The face plate has thousands of impinging holes. The design key is to keep pressure drop distribution on the showerhead face plate with the holes. This study reads the methodology to apply to a showerhead hole design. A Hagen-Poiseuille equation gives the pressure drop in a fluid flowing through such hole. The assumptions of the equation are the fluid is viscous-incompressible and the flow is laminar fully developed in a through hole. An equation can be expressed with radius R and length L related to the volume flow rate Q from the Hagen-Poiseuille equation, $Q={\pi}R4{\Delta}p/8{\mu}L$, where ${\mu}$ is the viscosity and ${\Delta}p$ is the pressure drop. In present case, each hole has steps at both the inlet and the outlet, and the fluid appears compressible. So we simplify the equation as $Q=C(R,L){\Delta}p$. A series of performance curves for a through hole with geometric parameters were obtained using two-dimensional numerical simulation. We obtained a relation between the hole diameter and hole length from the test cases to determine hole diameter at fixed hole length. A numerical simulation has been performed as a tool for enhancing showerhead robust design from flow structure. Geometric parameters for the design were post distribution and face plate thickness. The reinforced showerhead has been installed and its effective deposition profile is being shown in factory.

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Effect of field location and spray device on pesticide residue in chilli peppers (농약 살포조건이 고추열매 중 잔류에 미치는 영향)

  • Son, Kyeong-Ae;Kang, Tae-Kyeong;Park, Byeong-Jun;Kim, Taek-Kyum;Gil, Geun-Hwan;Kim, Chan-Sub;Kim, Jin-Bae;Im, Geon-Jae;Lee, Key-Woon
    • The Korean Journal of Pesticide Science
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    • v.16 no.3
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    • pp.230-235
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    • 2012
  • This study was carried out to clarify effects of field location and sprayer on the level of pesticide residue in chilli peppers. As confirmed by statistical analysis, the residue levels in green pepper among three greenhouses did not show significant difference at the first day after spraying with the same engine sprayer and nozzle. But the residue levels in green peppers collected from the exposed outside of crop were 2 times higher than those from the hidden inside. The sampling site was one of variation elements of pesticide residue. The residue levels after application by knapsack engine powered sprayer were 1.7 times higher than those by manual compressed sprayer. As the spraying pressure of the engine power sprayer is 2 times higher than the commonly used pressure of the manual compressed sprayer, the pressure of the sprayer and nozzles were considered to affect on the residue levels in peppers.

Capability of CO2 on Metal-Organic Frameworks-Based Porous Adsorbents and Their Challenges to Pressure Swing Adsorption Applications (금속-유기 골격계 다공성 흡착제의 이산화탄소 흡착성능과 압력순환흡착 공정 적용의 문제점)

  • Kim, Moon Hyeon;Choi, Sang Ok;Choo, Soo Tae
    • Clean Technology
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    • v.19 no.4
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    • pp.370-378
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    • 2013
  • This review has shown the capability of MOFs and ZIFs materials to adsorb $CO_2$ under typical PSA temperatures and pressures. The usual operating conditions are adsorption temperatures of $15{\sim}40^{\circ}C$ and adsorption pressures of 4~6 bar based on numerous PSA processes which are widely employed in gases industry for adsorptive separation of $CO_2$. The extent of $CO_2$ adsorption on the microporous materials depends on the metal species and organic linkers existing in the frameworks. The pore size and the surface area, and the process variables are the key parameters to be associated with the efficiency of the adsorbents, particularly adsorption pressures if other variables are comparable each other. The MOFs and ZIFs materials require high pressures greater than 15 bar to yield significant $CO_2$ uptakes. They possess a $CO_2$ adsorption capacity which is very similar to or less than that of conventional benchmark adsorbents such as zeolites and activated carbons. Consequently, those materials have been much less cost-effective for adsorptive $CO_2$ separation to date because of very high production price and the absence of commercially-proven PSA processes using such new adsorbents.

Hydraulic Characteristics of Deep and Low Permeable Rock Masses in Gyeongju Area by High Precision Constant Pressure Injection Test (고정밀도 정압 주입시험에 의한 경주 지역 대심도 저투수성 암반 수리특성 연구)

  • Bae, SeongHo;Kim, Hagsoo;Kim, Jangsoon;Park, Eui Seob;Jo, Yeonguk;Ji, Taegu;Won, Kyung-Sik
    • Tunnel and Underground Space
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    • v.31 no.4
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    • pp.243-269
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    • 2021
  • Since the early 2010s, the social importance of research and practical projects targeting deep geological disposal of high-level nuclear waste, underground CO2 storage and characterization of deep subsurface by borehole investigation has been increasing. In this regard, there is also a significant increase in the need for in situ test technology to obtain quantitative and reliable information on the hydraulic characteristics of deep rock mass. Through years of research and development, we have independently set up Deep borehole Hydraulic Test System (DHTS) based on the key apparatuses designed and made with our own technology. Using this system, high precision constant pressure injection tests were successfully completed at the two 1 km boreholes located in Mesozoic granite and sedimentary rock regions, Gyeongju. During the field tests, it was possible to measure very low flow rate below 0.01 l/min with micro flow rate injection/control module. In this paper, the major characteristics of DHTS are introduced and also some results obtained from the high precision field tests under the deep and low permeable rock mass environment are briefly discussed.

Numerical Investigation of Aerodynamic Characteristics of a Ducted Fan-Vane Configuration and Improvement of Control Performance in Hover (덕트 팬-베인 형상의 제자리 비행 공력 특성 및 조종 성능 개선에 관한 수치적 연구)

  • Kang, Dong Hun;Yim, Jinwoo;You, Heung-Cheol
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.49 no.3
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    • pp.221-231
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    • 2021
  • In the present study, numerical simulation was performed to investigate aerodynamic characteristics of a ducted fan-upper/lower vanes system in hover. Sensitivity analysis of aerodynamic forces for a system component was conducted with the deflection angle of upper vanes varying but at the constant rotational speed and the collective pitch angle of fan blades. Then, vane control performance and duct airload distributions were analyzed in detail to physically understand operating mechanisms of individual vane and interference effect between duct and vanes. Finally, new control concept of operating upper vanes has been proposed to improve the control performance of the full configuration. It is found that the side force and rolling moment of upper vanes increase linearly with the variation of those deflection angle; however, the total side force is significantly small due to the reaction force acted on the duct. It is also found that upper vanes close to the duct contraction side have a key role in changing vane control forces. It is revealed that the duct suction pressure is induced by the interaction with the suction side of upper vanes, while duct pressure recovery by the interaction with the pressure side, leading to increase in duct asymmetric force. When four upper vanes are kept in situ at 0° deflection angle or removed, the total control performance was improved with duct asymmetric force reduced and the total magnitude of roll remarkably increasing up to 80%.

Study on the High Pressure Combustion Performance Characteristics of the 1st Row Pintle Injector using LOx-Kerosene as Propellant (LOx와 Kerosene을 추진제로 하는 1열 핀틀 분사기의 고압 연소성능 특성에 관한 연구)

  • Kang, Donghyuk;Kim, Jonggyu;Ryu, Chulsung;Ko, Youngsung
    • Journal of Aerospace System Engineering
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    • v.16 no.5
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    • pp.17-25
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    • 2022
  • The pintle injector has many advantages in the key characteristics of a liquid rocket engine, such as combustion stability, combustion efficiency, and wide range of comprehensive thrust control, design and manufacture, and test fired under supercritical conditions. The pintle injector is manufactured with a rectangular, single-row orifice for thrust control and production considerations. In order to verify the combustion performance of the pintle injector and its potential as a commercial injector, the combustion characteristics were analyzed by varying the TMR (Total Momentum Ratio) and BF (Blockage Factor). The result of the hot firing test showed that the heat flux increased as TMR increased, and it confirmed that the characteristic velocity efficiency was more affected by BF than TMR. Suppose a single-row pintle injector with efficiency characteristics insensitive to changes in TMR can achieve high efficiency at low fuel differential pressure conditions. In that case, the variable pintle injector's design flexibility can be increase.