• Journal of the Korea institute for structural maintenance and inspection
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• v.25 no.3
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• pp.57-67
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• 2021

A thorough administration of the arterial road network requires a continuous supply of updated and accurate information about the traffic that travels on the roads. One of the ways to effectively obtain the traffic volume and weight distribution of heavy vehicles is the BWIM technique, which is actively being studied. Unlike previous studies, this study was performed to develop a simplified Bridge Weigh-In-Motion (BWIM) algorithm that can easily estimate the axle spacing and weight of a traveling vehicle by utilizing the structural characteristics of the bridge. A short span RC T-beam bridge with no crossbeam installed was selected for the study, and then the strain response characteristics of bridge deck and girder was checked through preliminary field test. Based on the preliminary field test results, a simplified BWIM algorithm suitable for the bridge to be studied was derived. The validity and accuracy of the BWIM algorithm derived in this study were verified through field test. As a result of the verification test, the proposed BWIM algorithm can estimate the axle spacing and gross weight of the travelling vehicles with the average percent error of less than 3%.

• Radiation Oncology Journal
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• v.9 no.2
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• pp.215-219
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• 1991

To evaluate the effect of MVP chemotherapy and hyperfractionated radiotherapy in Stage III unresectable non small cell lung cancer (NSCLC), authors have conducted a prospective randomized study since January 1991, Stage IIIa or IIIb unresectable NSCLC patients were treated with hyperfractionated radiotherapy (120 cGy/fx BID) up to 6500 cGy following 3 cycles of induction MVP (Mitomycin C 6 mg/$m^2$, Vinblastine 6 mg/$m^2$, Cisplatin 60 mg/$m^2$) and randomized for either observation or 3 cycles of maintenance MVP chemotherapy. Until August 1991, 18 patients were registered to this study. 4 cases were stage IIIa and 14 were stage IIIb. Among 18 cases 2 were lost after 2 cycles of chemotherapy, and 46 were analyzed for this preliminary report. The response rate of induction chemotherapy was $62.5\%$ : partial response, $50\%$ and minimal response, $12.5\%$. Residual tumor of the one partial responder was completely disappeared after radiotherapy. Among 6 cases who were progressed during induction chemotherapy, 4 of them were also progressed after radiotherapy. All patients were tolerated BID radiotherapy without definite increase of acute complications, compared with conventional radiotherapy group. But at the time of this report, one patient expired in two month after the completion of the radiotherapy because of treatment related complication. Although the longer follow up is needed, authors are encouraged with higher response rate and acceptable toxicity of this treatment. Authors believe that this study is worthwhile to continue.

• Journal of the Korean Society of Marine Environment & Safety
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• v.22 no.4
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• pp.354-361
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• 2016

While the amounts of oil spill caused by the VLCC Hebei Spirit indicated 2.5 times more than that of the VLCC Sea Prince, the economic, environmental, and social damages derived from the Hebei Spirit spill were estimated to be about 30 times greater than those from the Sea Prince incident. This study consolidates the appropriate justification for building a multi-purpose large oil spill response vessel to allow swift and efficient handling of catastrophic marine pollution events through an analysis of technical and economic feasibility of such a project. The result of the technical feasibility analysis illustrates that a hopper dredge and oil spill response vessel with a capacity of 4,000 tons should be more appropriate. The result of the economic feasibility analysis indicates that under the most conservative estimates the project appears to be slightly impractical, with a benefit/cost ratio of 0.82, in which self-help efforts, however, can facilitate the project. And medium to optimistic estimates present benefit/cost ratios are estimated to be 2.72 and 5.82 respectively, representing apparent economic feasibility.

• Clinical and Experimental Pediatrics
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• v.46 no.4
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• pp.335-339
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• 2003

Purpose : Surfactant protein A(SP-A) is involved in surfactant physiology and structure, and plays a major role in innate host defense and inflammatory processes in the lung. Steroid therapy is widely used for mothers who threaten to deliver prematurely and also used commonly in the management of preterm infants with chronic lung disease. Two SP-A genes(SP-A1, SP-A2) and several alleles have been characterized for each SP-A gene in human. Preliminary evidence indicates that differences may exist among alleles in response to Dexamethasone(Dexa) and that the SP-A 3'UTR plays a role in this process. We studied whether 3'UTR-mediated differences exist among the most frequently found SP-A alleles in response to Dexa. Methods : Constructs containing the 3'UTR from eight different SP-A alleles were made using luciferase as a the reporter gene. These constructs were driven by the SV40 promotor and were transfected along with a transfection control vector in H441 cells that express SP-A. The activity of the reporter gene in the presence or absence of Dexa(100 nM) treatment was measured. All the experiments for the eight SP-A alleles studied, were performed in triplicate and repeated five times. The results were normalized to the transfection control. Results : Expression of alleles of 6A3, 6A, 1A were significantly decreased in response to Dexa. Conclusion : Three UTR mediated differences exist among human SP-A variants both in the basal expression and in response to Dexa. These genotype-dependent differences may point to a need for a careful consideration of individual use of steroid treatment in the prematurely born infant.

• Journal of the Korean Geotechnical Society
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• v.37 no.12
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• pp.73-87
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• 2021

Pile-supported wharf is a structure that can transmit and receive cargo, and it is mainly installed on saturated inclined ground. In the seismic design of these structures, the codes suggest using the response spectrum analysis method as a preliminary design method. However, guideline on modeling method for pile-supported wharf installed in saturated soil is lacking. Therefore, in this study, the dynamic centrifuge model test and response spectrum analysis were performed to evaluate the seismic performance of pile-supported wharf installed into the saturated soil. For the test, some sections (3×3 pile group) among the pile-supported wharf were selected, and they were classified into two model (dry and saturated sand model). Then the response spectrum analysis was performed by using the soil spring method to the test model. As a result of test and analysis, the m om ent difference occurred within a m axim um of 51% in the dry sand m odel and the saturated sand model where liquefaction does not occur, and it was found that the pile moment by depth was properly simulated. Therefore, in the case of these models, it is appropriate to perform the modeling using the Terzaghi (1955) constant of horizontal subgrade reaction (n_h)

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2009.10a
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• pp.797-803
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• 2009

The accurate prediction of dynamic characteristics of high speed rotors, such as gas turbines, is important to avoid the possibility of operating the machinery near the critical speeds or unstable speed regions. However, the dynamic analysis methods and softwares for gas turbines have been developed in the process of producing many gas turbines by manufacturers and most of them have seldom been disclosed to the public. Recently, commercial FEM softwares, such as SAMCEF, ANSYS and NASTRAN, started supporting some rotordynamics analysis modules based on 3-D finite elements. In this paper, the dynamic analysis method using commercial S/W, especially ANSYS, is attempted for the small-size gas turbine engine rotor, and the analysis capability and limitations of its rotordyamics module are evaluated for further improvement of the module. As the preliminary procedure, the rotordyamic analysis capability of ANSYS was tested and evaluated with the reference models of the well-known dynamics. The limitations in application of the rotordynamics module were then identified. Under the current capability and limitations of ANSYS, it is shown that Lee diagram, a new frequency-speed diagram enhanced with the concept of $H{\infty}$ in rotating machinery, can be indirectly obtained from FRFs computed from harmonic response analysis of ANSYS. Finally, it is demonstrated based on the modeling and analysis method developed in the process of the S/W verification that the conventional Campbell diagram, Lee diagram, mode shapes and critical speeds of the small-size gas turbine engine rotor can be computed using the ANSYS rotordynamics module.

• Earthquakes and Structures
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• v.3 no.2
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• pp.141-168
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• 2012

The Retrofit Yield Spectrum (RYS) is a new spectrum-based device that relates seismic demand of a retrofitted structure with the fundamental design parameters of the retrofit. This is obtained from superposition of Yield Point Spectra with design charts that summarize in pertinent spectrum-compatible coordinates the attributes of a number of alternative retrofit scenarios. Therefore, once the requirements for upgrading a given structure have been determined, the RYS enable direct insight of the sensitivity of the seismic response of the upgraded structure to the preliminary design decisions made while establishing the retrofit plan. By virtue of their spectrum-based origin, RYS are derived with reference to a single mode of structural vibration; a primary objective is to control the contribution of this mode in the retrofit design so as to produce a desirable distribution of damage at the ultimate limit state by removing soft storey formations and engaging the maximum number of structural members in deformation, in response to the input motion. Calculations are performed with reference to the yield-point, where secant stiffness is proportional to the flexural strength of reinforced concrete members. Derivation and use of the Retrofit Yield Spectra (RYS) refers to the seismic demand expressed either in terms of spectral acceleration, spectral displacement or interstory drift, at yield of the first storey. A reinforced concrete building that has been tested in full scale to a sequence of simulated earthquake excitations is used in the paper as a demonstration case study to examine the effectiveness of the proposed methodology.

• The Research Journal of the Costume Culture
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• v.28 no.2
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• pp.265-284
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• 2020

This study aimed to analyze the performance of Disney-collaborated fashion lines based on online consumer reviews. To do so, the researchers employed text mining and network analysis to identify key words in the reviews of these products. Blogs, internet cafes, and web documents provided by Naver, Daum, and YoutTube were selected as subjects for the analysis. The analysis period was limited to one year after for the 2019. Data collection and analysis were conducted using Python 3.7, Textom, and NodeXL. The research terms in question were as follows: 'Disney fashion collaboration' and 'Frozen fashion collaboration'. Preliminary survey results indicated that 'Elsa's dress' was the most frequently mentioned term and that the domestic fashion brand Eland Retail was the most active in selling Disney branded clothing through its own brand. The writers of reviews for Disney-collaborated fashion products were primarily mothers with daughters. Their decision to purchase these products was based upon the following factors; price, size, stability of decoration, shipping, laundry, and retailer. The motives for purchasing the product were the positive response of the consumer's child and the satisfaction of the parents due to the child's response. The problems to be solved included insufficient quantity of supply, delay in delivery, expensive price considering the number of times children's clothes are worn, poor glitter decoration, faded color, contamination from laundry, and undesirable smells immediately after the purchase.

• Computers and Concrete
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• v.15 no.6
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• pp.951-972
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• 2015

The focus of the present study is to investigate both local and global behaviour of a precast concrete sandwich panel. The selected prototype consists of two reinforced concrete layers coupled by a system of cold-drawn steel profiles and one intermediate layer of insulating material. High-definition nonlinear finite element (FE) models, based on 3D brick and 2D interface elements, are used to assess the capacity of this technology under shear, tension and compression. Geometrical nonlinearities are accounted via large displacement-large strain formulation, whilst material nonlinearities are included, in the series of simulations, by means of Von Mises yielding criterion for steel elements and a classical total strain crack model for concrete; a bond-slip constitutive law is additionally adopted to reproduce steel profile-concrete layer interaction. First, constitutive models are calibrated on the basis of preliminary pull and pull-out tests for steel and concrete, respectively. Geometrically and materially nonlinear FE simulations are performed, in compliance with experimental tests, to validate the proposed modeling approach and characterize shear, compressive and tensile response of this system, in terms of global capacity curves and local stress/strain distributions. Based on these experimental and numerical data, the structural performance is then quantified under various loading conditions, aimed to reproduce the behaviour of this solution during production, transport, construction and service conditions.

• Journal of Animal Science and Technology
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• v.60 no.7
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• pp.18.1-18.12
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• 2018

Background: Xanthosine treatment has been previously reported to increase mammary stem cell population and milk production in cattle and goats. However, the underlying molecular mechanisms associated with the increase in stem cell population and milk production remain unclear. Methods: Primiparous Beetal goats were assigned to the study. Five days post-partum, one mammary gland of each goat was infused with xanthosine (TRT) twice daily ($2{\times}$) for 3 days consecutively, and the other gland served as a control (CON). Milk samples from the TRT and CON glands were collected on the 10th day after the last xanthosine infusion and the total RNA was isolated from milk fat globules (MEGs). Total RNA in MFGs was mainly derived from the milk epithelial cells (MECs) as evidenced by expression of milk synthesis genes. Significant differentially expressed genes (DEGs) were subjected to Gene Ontology (GO) terms using PANTHER and gene networks were generated using STRING db. Results: Preliminary analysis indicated that each individual goat responded to xanthosine treatment differently, with this trend being correlated with specific DEGs within the same animal's mammary gland. Several pathways are impacted by these DEGs, including cell communication, cell proliferation and anti-microbials. Conclusions: This study provides valuable insights into transcriptomic changes in milk producing epithelial cells in response to xanthosine treatment. Further characterization of DEGs identified in this study is likely to delineate the molecular mechanisms of increased milk production and stem or progenitor cell population by the xanthosine treatment.