• 반도체디스플레이기술학회지
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• 제9권3호
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• pp.47-51
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• 2010

This paper presents a wafer pre-alignment system which is improved using the image of the entire wafer area. In the previous method, image acquisition for wafer takes about 80% of total pre-alignment time. The proposed system uses only one image of entire wafer area via a high-resolution CMOS camera, and so image acquisition accounts for nearly 1% of total process time. The larger FOV(field of view) to use the image of the entire wafer area worsen camera lens distortion. A camera calibration using high order polynomials is used for accurate lens distortion correction. And template matching is used to find a correct notch's position. The performance of the proposed system was demonstrated by experiments of wafer center alignment and notch alignment.

• Journal of Preventive Medicine and Public Health
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• 제56권4호
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• pp.384-387
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• 2023

The aim of this study was to present a framework for clinicians to use when discussing electronic cigarette (e-cigarette) use and its association with pre-diabetes. A communication tool was designed using evidence-based strategies from the academic literature. A four-step framework is presented, which includes: step (1) helping patients to understand the association between e-cigarette use and pre-diabetes; step (2) the synergistic health impacts of e-cigarette use and pre-diabetes; step (3) management of diabetes-related lifestyle factors; and step (4) stages of change assessment related to e-cigarette reduction. This communication tool provides support for clinicians to discuss the risk of pre-diabetes associated with e-cigarette use. Moving forward, implementation and evaluation of this model are needed.

• Animal cells and systems
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• 제15권3호
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• pp.211-218
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• 2011

Fragmentation in human pre-implantation embryos has been suggested as the process of apoptosis. We have previously demonstrated a direct relationship between the increased reactive oxygen species (ROS) and apoptosis in human pre-implantation embryos. ROS is known to suppress the function of mitochondria in which steroidogenic acute regulatory protein (StAR) and peripheral-type benzodiazepine receptor (PBR) are presented. Therefore, the purpose of this study was to examine the expression of StAR and PBR in human pre-implantation embryos and to evaluate whether reduction of these proteins is associated with apoptosis. Apoptosis was detected by annexin V-fluorescein isothiocyanate (FITC) and mitochondrial membrane potential was measured by 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethyl-benzimidazolyl-carbocyanine iodide (JC-1). Immunofluorescence staining and Western blotting were applied to examine the expression of StAR and PBR in the embryos. Lipid droplets in the embryos were stained with Oil Red O. The fragmented pre-implantation embryos were stained with annexin V-FITC, but not the normal ones. The mitochondria with active membrane potential were present less in the fragmented embryos compared with the non-fragmented embryos. We also confirmed that both StAR and PBR were expressed in the embryos and their expression levels were lower in the fragmented ones. In addition, the number and size of lipid droplets were increased in the fragmented embryos. The present study provides evidence that reduction of StAR and PBR in human pre-implantation embryos is associated with an increase in the lipid droplets leading to apoptosis.

• 복식문화연구
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• 제28권5호
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• pp.669-676
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• 2020

The purpose of this research was to revive the bathochromic effects of wool fabrics by using natural dyestuffs with minimum heavy metallic mordants. The natural dyestuffs used in this research were the indigo plant, Phellodendron amurense, and Caesalpinia sappan. Sample no. 1 was pre-dyed five times with indigo. Sample no. 2 was pre-dyed five times with indigo and then once dyed with Phellodendron amurense. Following the same method as sample no. 2 with an additional Phellodendron, Sample no. 3 consisted of a pre-dye five times with indigo and twice with Phellodendron amurense. Sample no. 4 was pre-dyed six times with indigo and then once dyed with Caesalpinia sappan. Sample no. 5 followed the same method as no. 4 with an additional dye of Caesalpinia sappan. Sample no. 6 was pre-dyed five times with indigo and then once dyed with Phellodendron amurense and once dyed with Caesalpinia sappan. The results were as follows: first, all samples showed deeper colors. Second, according to the results of the surface K/S measurement, the surface K/S of wool fabrics was >20. Third, the results of lightfastness measurement showed superiority over grade 4 in samples no. 1, 2, 3, 5, and 6. However, sample no. 4 was grade 3. In the colorfastness to washing measurement, sample no. 2 showed greater superiority than grade 3-4, while samples no. 1 and 3 were grade 3. In addition, the colorfastness to dry cleaning for all samples was satisfactory or excellent by more than grade 3.

• 환경생물
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• 제39권4호
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• pp.452-462
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• 2021

Pretilachlor (PRE)는 전 세계적으로 사용되는 아세트아닐리드계 제초제이며 수생 광영양생물에 미치는 영향에 대해서는 알려진 바가 거의 없다. 본 연구에서 해양 와편모조류 P. minimum를 대상으로 PRE의 생리적, 분자적 독성 영향을 평가하였다. 그 결과, PRE는 P. minimum의 성장률, 색소, 광합성 지표를 유의하게 감소시켰다. 또한, 광합성 관련 유전자 PmpsbA, PmpsaA 및 항산화 단백질 PmGST의 상대적 유전자 발현율과 세포 내 ROS 증가가 유의하였다. 이는 PRE가 P. minimum의 광합성 효율 저하 및 광계 손상을 야기하며, GST가 세포 내 산화 스트레스 및 PRE의 무독화에 관여함을 보여준다. 본 연구 결과는 PRE를 비롯한 아세트아닐라이드계 제초제가 해양 와편모조류의 세포 독성을 야기하며, 광합성 저해가 스트레스의 주요 원인임을 제시한다. 다른 아세트아닐라이드계 제초제가 비표적 광영양 생물에게 미치는 독성 영향은 아직 연구가 부족하므로, 향후 연구에서 다양한 생물종을 대상으로 추가 연구가 필요하다.

• Journal of Genetic Medicine
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• 제8권1호
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• pp.17-27
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• 2011

자간전증은 전세계적으로 모성 및 주산기 사망과 이환의 주된 원인이나 아직까지 병인기전은 명확하게 규명되지 않은 실정이다. 자간전증은 일반적으로 두 단계 질환으로 알려져 있으며, 그 임상의 첫 단계는 모체의 나선동맥의 얕은 세포영양아층 침투에 의한 태반 부전이 발생한다. 태반 부전에 의한 허혈성 태반이 모체의 순환 혈류 내로 용해성 인자와 싸이토카인, 영양막 조직파편을 유리하면, 전신적인 내피세포 손상 및 기능 부전을 야기하고, 이로 인하여 자간전증 이차 단계인 모체 증후군이 나타난다. 역학적 연구에서 자간전증에 대한 유전적 소인이 일관되게 증명되었다. 집중적 연구 노력에 의한 감수성 유전자 발견은 자간전증의 병태생리를 이해하는데 있어서 유용한 정보를 줄 것이며 자간전증의 치료 및 예방 방법에 대한 방향을 제시할 것이다. 본 주제에서는 자간전증의 병태생리에 있어서 유전적 요인의 역할에 대한 최신 이해를 요약하고 자간전증의 유전적 실마리를 찾기 위한 분자적 접근에 대해 설명하고자 한다.

• 한국농공학회지
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• 제17권4호
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• pp.3921-3930
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• 1975

This research was carried out to investigate several mechanical characteristics of pre-stressed steel beams. The configuration of specimens used for this study were as follows; a cover plate having permissible fiber stress of 4,000 kg/$\textrm{cm}^2$ was welded at bottom having the allowable bending stress 2500 kg/$\textrm{cm}^2$ steel beam, the section ratios of pre-stressed steel beam and cover plate were 0.5 and 0.6. Adopted pre-stresses were 0%, 50%, and 100% of an allowable fiber stress of a steel beam. The results obtained from the study may be summarized as follows; 1. The elastic range of a beam was increased by the application of pre-stress to the beam, which leads to a lighter section. 2. The permissible moment capacity of a pre-stressed steel beam was greated than that of a steel beam without pre-stressing. 3. The equivalent allowable stress induced by adopting the different section ratio of pre-stressed beam to cover plate were figured out 4. The optimum value of section ratio of beam and cover plate was 0.3 to 0.4 in case of a 1.5m span composite beam, a combination of an allowable stress 2,500kg/$\textrm{cm}^2$ steel beam and a permissible fiber stress 4,000 kg/$\textrm{cm}^2$ steel cover plate, was used. 5. The magnitude of the pre-stress was desirable to be same as the allowable stress of a steel beam. 6. It was concluded that if the construction techniques in the field are developed and improved, the practicing of pre-stress to the steel structure has a promising future.

• 한국수학교육학회지시리즈A:수학교육
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• 제51권2호
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• pp.131-144
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• 2012

The purpose of this study is to investigate the change of mathematics pre-service teachers' teaching behaviors in microteaching. This study is organized along the following lines: 1) mathematics pre-service teachers conduct twice microteachings, 2) the microteaching recordings and lesson observation reports written by pre-service teachers are analyzed. Through reviewing the first microteaching, pre-service teacher have reviewed and found out improvements of their teaching. In the second microteaching, pre-service teachers' teaching behaviors have been positively and effectively changed with respect to teaching methods, proposal of learning objectives, prior knowledge usage, presenting lesson's content, concise descriptions, brief language usages, multimedia, and appropriate questions. However, they frequently used inappropriate expressions from their unconscious habits. Therefore, the educational institutions should provide opportunities involved in well-structured microteaching training program with pre-service teachers, which in turn, help pre-service teachers to have more positive teaching competence.

• Journal of Korean Biological Nursing Science
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• 제13권2호
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• pp.117-124
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• 2011

Purpose: Dyslipidemia is one of the most important cardiovascular risk factors. The purpose of this study was to compare serum lipid levels in college students and pre-graduates. Methods: Data were obtained from student health examination in one university located in Kyunggi-province. Participants were 440 college students and 1973 pre-graduates. The data were collected in May of 2010. T-test, Chi-square test, Fisher's exact test, and multiple regression with dummy variables using SAS version 9.1 were performed. Results: Pre-graduates showed significantly higher level of total cholesterol, triglyceride, and LDL than college students. There was no significant difference in alcohol drinking between college students and pre-graduates. However, smoking and diet behavior were significantly different; pre-graduates were more likely being current smoker and recommended to change diet behavior. When adjusting covariates including general and behavioral characteristic, pre-graduates had significantly higher total cholesterol (p<.001), triglyceride (p=.003), and LDL (p=.003). Among covariates, smoking was significantly related to triglyceride, particularly past smokers. Conclusion: There is a need to develop a lipid-reducing program targeting pre-graduates. This program should be considered behavioral factors, particularly smoking. In addition, given the fact that pre-graduates had unhealthy habits compared with college students, interventions for correcting health behaviors in this population are required.

• 대한지구과학교육학회지
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• 제10권2호
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• pp.226-234
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• 2017

본 연구의 목적은 '지층과 암석' 강좌를 수강하는 초등예비교사들을 대상으로 스토리텔링 기법 적용하여 과학개념 습득 및 과학교수효능감에 미치는 효과를 알아보는 것이다. 이를 위하여 '지층과 암석' 강좌를 수강하는 심화과정 1개 반(32명)을 대상으로 3월부터 6월까지 15주에 거쳐 실험처치를 하였다. 실험처치는 한 학기의 '지층과 암석'의 강좌를 수강하는 것이며 초등예비교사들이 모둠별 스토리텔링 기법으로 수업 시연을 하는 것으로 마무리 하였다. 연구의 결과 및 분석은 연구집단의 전-후 검사에서 대응 표본 t 검정으로 분석하였다. 본 연구의 결과와 논의를 바탕으로 결론을 내리면 다음과 같다. 첫째, 초등예비 교사의 스토리텔링 기법 적용은 과학개념 습득에 효과가 있었다. 둘째, 초등예비 교사의 스토리텔링 기법 적용은 과학교수효능감 함양에 효과가 있었다. 셋째, 초등예비 교사의 스토리텔링 기법 적용 수업은 긍정적인 반응을 보였다.