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Improvement of Pregnancy Rate by the Selection of Early Cleavage Embryos to 2-cell Stage in Human IVF (2세포기로의 조기난할 배아 선발을 이용한 체외수정술의 임신율 증가)

  • Park, Sea Hee;Joo, Bo Sun;Lee, Su Kyung;Kim, Kyung Sue;Moon, Hwa Sook
    • Clinical and Experimental Reproductive Medicine
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    • v.32 no.1
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    • pp.47-54
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    • 2005
  • Objective: Evaluation of embryos using early cleavage to 2-cell stage has been proposed, but a critical time-point for selecting embryos is unclear. The aim of the present study is to provide a guideline including critical time-point in the selection of early cleaving embryo for the reduction of multiple pregnancies as well as the increase of pregnancy rate in human IVF. Methods: This prospective study was performed in 116 cycles from 85 patients who underwent conventional IVF or ICSI at the infertility clinic of Good Moonhwa Hospital from January 2002 to December 2003. Early cleavage (EC) of embryos to 2-cell stage was assessed at 25 h and 27 h postinsemination/microinjection. Embryos that had early cleaved at each time point were designated as EC-1 and EC-2, respectively, while others were designated as non-early cleavage (NEC). Results: At least one early cleavage embryo was observed in 54 (46.6%) for the EC-1 and 84 (72.4%) for the EC-2 of the 116 cycles assessed. Clinical pregnancy rates (PR) were significantly higher in the EC-1 group (66.7%) compared to the EC-2 group (53.6%) or the NEC group (31.2%) (p<0.05). Significant improvement of the pregnancy rate was found when at least two or more embryos were early cleaved at 25 h postinsemination or when the proportion of early cleavage embryo at 25 h postinsemination was higher than 20% (p<0.05). Conclusion: The critical time-point for the selection of early cleavage embryos with high implantation potential is more effective in 25 h postinsemination/microinjection compared to 27 h. The proportion as well as number of early cleavage embryos is also an important factor for the prediction of pregnancy outcome and the chance of multiple pregnancies. These results demonstrated that the evaluation of early cleavage embryos to 2-cell stage is an easy, simple, and objective method for the selection of good quality embryos suitable for embryo transfer.

Complementary Color Scheme Which Appeared in Women's Fashion Collections of New York, Milan, Paris, and London

  • Kwon, Hae-Sook
    • Journal of Fashion Business
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    • v.13 no.6
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    • pp.125-136
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    • 2009
  • The main objective of this research was to understand the characteristics of complementary color scheme through the analysis of contemporary women's fashion color coordination as they appear in the 'Collections'. Data collection of 115 was done through review of 'pr$\hat{e}$t-$\grave{a}$-porter Collections' of four cities; Milan, London, New York, Paris. Statistical analysis of frequency and also qualitative interpretation of characteristics of complementary color harmony characteristics which appeared in four collections were completed. The main findings were as followed; (1) Only 115 complementary color schemes out of 4968 two color combinations appeared. Compared the comparative ratios of appearance frequency between the two color combination and the complementary color harmony, London showed the highest, and followed by New York, and Milan and Paris. (2)The combined color type of 'red+green' was the most frequently appeared, and followed by 'violet+yellow' and 'orange+blue'. For the type of tone harmony, the contrast tone showed the most, and followed by the similarity and identity. According to the type of complementary color combination, the type of tone harmony used differently. Some differences showed in the types of color harmony and tone harmony between collections. (3) The complementary color scheme which shown in four collections harmonized two opposite colors mainly through the strong tone contrast and this could cause tension along with interest in the image. The complementary colors intensified and brought out the attributes each other. More details, high contrast of two complementary colors of yellow and violet created a vibrant look especially when used at higher saturation. Sometimes, however, some tone variations of two hues neutralized the strong effect and sometimes enhanced each other. When they used in similarity tones or identity tones in light colors, the tension was reduced and became softened but still presented nice harmony. In the type of 'red+green' color harmony, the various color combinations were demonstrated, mostly through tone manipulation of green color. The similarity tone harmony, which used the most, could effect a better sense of harmony and present more sophisticated looks. When used in contrast tone harmony, some changes in its own color which have only one color of two the excessive intensity led a good harmony. The 'orange+blue' color harmony was shown the least and used three tone harmony almost the same ratio. In this color harmony, blue amplified its energy and brilliance of orange and seemed to work better when one color was at a lower intensity than the other. In harmony with a similarity and an identity tone, this color harmony produces a stable and calm image. (4) The complementary scheme appeared more frequently in the S/S collections than in A/W collections and showed some differences in the types of color harmony and tone harmony between seasons, however, no big differences between collections.

Cardiovascular Neurons Mediating Somatosympathetic Reflex in Rostral Ventrolateral Medulla

  • Goo, Yong-Sook;Kim, Sang-Jeong;Kim, Jun;Sung, Ho-Kyung
    • The Korean Journal of Physiology
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    • v.27 no.2
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    • pp.185-197
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    • 1993
  • The rostral ventrolateral medulla (RVLM) includes vasopressor neurons, which transmit activation signals to the intermediolateral nucleus (IML) of the spinal cord, where the preganglionic sympathetic nucleus is located, to raise arterial blood pressure (BP). However, controversy exists as to the possible depressor area in the RVLM and the pathway involved. The present study persued evidence far the location of depressor neurons and the pathway by simultaneously observing changes in BP and the firing rate (FR) of cardiovascular neurons (CVNs) in the RVLM during the somatosympathetic reflex (SSR) elicited by peripheral nerve stimulation, since CVNs are known to contribute to the generation of the sympathetic nerve discharge. In 42 cats, anaesthetized with $\alpha-chloralose$, single unit recording was performed, using carbon filament electrodes inserted into the RVLM, enabling estimation of the post R wave unit histogram (PR-UNlT) and the spike triggered average of sympathetic nerve discharge (STA-SND), allowing identification of CVNs. Antidromic stimulation of spinal $T_2$ segment was followed to determine whether the identified CVN projects axonal endings to the spinal cord (reticulospinal neuron). The sciatic nerve was electrically stimulated at $A\delta-intensity$ (1 mA, 0.1 ms), 1 Hz and C-intensity (10 mA, 0.5 ms), 20 Hz to elicit the depressor, and pressor responses of the SSR, respectively. Simultaneous measurement of CVN firing rate was made. Experimental results are summarized as follows. 1) 20 out of 98 CVNs had axonal projections to the spinal cord and 17 out of 98 CVNs showed FR changes during SSR. 2) Response patterns of FR and BP during SSR were classified into 8 types. 3) These 8 different response patterns could be further classified into those from pressor and depressor neurons. These results demonstrate that some CVNs were identifiable as reticulospinal neurons responding to anti-dromic stimulation and that CVNs operating as depressor neurons as well as pressor neurons exist in the RVLM, both of which are involved with SSR mediation. Therefore, evidence was found that an independent depressor pathway might be involved in the mediation of SSR.

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Plant Regeneration and Genetic Diversity of Regenerants from Seed-derived Callus of Reed (Phragmites communis Trinius) (갈대(Phragmites communis Trinius) 성숙종자를 이용한 기내 식물체 재분화와 재분화체의 유전적 다양성)

  • Ryu, Jaihyunk;Kim, En-Hwan;So, Hyun-Su;Chung, Mi-Young;Song, Won-Seob;Bae, Chang-Hyu
    • Korean Journal of Plant Resources
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    • v.26 no.2
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    • pp.320-327
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    • 2013
  • This study was carried out to address an efficient in vitro regeneration system from seed-derived callus of Phragmites communis, and to evaluate genetic variations of the regenerants using ISSR markers. Shoot regeneration via calli was greatly influenced by N6 medium compared with MS medium, and plant regeneration frequency was 90% in N6 supplemented with BA 0.25 mg/L and BA 0.5 mg/L. According to ISSR analysis of the thirty regenerants, out of 94 loci detected overall, 16 were identified to be polymorphic with a rate (PR) of 17.0%. The mean gene diversity (h) of different in vitro condition was 0.03 and ranged from 0.008 for N6 with BA 5 mg/L, to 0.040 for MS with IAA 0.1 mg/L+kinetin 2 mg/L. The results indicate that the regenerants have a low genetic variation, and ISSR analysis is effective to detect genetic variation of regenerants.

Numerical Analysis of Natural Convection in Inclined Flat Plate Enclosures (경사진 평판형 밀폐 공간에서의 자연 대류 현상의 수치 해석)

  • Kim, Yong Hyun;Koh, Hak Kyun;Noh, Sang Ha
    • Journal of Biosystems Engineering
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    • v.10 no.1
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    • pp.24-38
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    • 1985
  • 경사진 밀폐 공간에서 마주 보는 두 벽면의 온도 차로 인하여 발생되는 자연 대류 현상은 여러 공학 분야에서 볼 수 있는 중요한 열전달 현상으로서, 최근 들어 평판형 태양열 집열기를 설계하려는 사람들에게 많은 관심의 대상이 되고 있다. 평판형 태양열 집열기의 경우 덮개판으로 부터의 대류 열손실을 감소시킴으로서 집열 효율을 높일 수 있을 뿐만 아니라 사용목적에 따라 소형 집열기를 제작할 수 있어 경제적으로 유리하게 될 것이다. 밀폐된 공간에서 최초에 정지 상태에 있는 얇은 유체층을 하부에서 가열시켜 주면 열팽창 현상이 일어나고, 이것에 의한 부력이 점도나 열전도도 등의 안정화 요인을 극복할 수 있을 정도로 커지면 System이 불안정하게 되어 자연 대류 현상이 수반되며 이 때문에 열전달율이 급격히 증가하게 된다. 이러한 현상의 지배 방정식은 연립 비선형 편미분 방정식으로 특수한 경계 조건외에는 일반적으로 해석적 해를 구하기가 어렵기 때문에 실험적 연구가 많이 실시되어 왔고 이들 결과의 대부분은 전반적인 열전달 특성치만을 구하는데 집중되어 왔다. 본 연구에서는 수치 해석법의 하나인 유한 차분법을 도입하여 이차원으로 가정한 경사진 평판형 밀폐 공간에서의 자연 대류 현상의 지배 방정식을 유한 차분화시켜, $$2.74{\times}10^3\leq_-Gr\leq_-2.0{\times}10^6$$, Pr=0.73, $$15^{\circ}\leq_-a\leq_-150^{\circ}$$, 종횡비는 1, 2, 3, 5, 9에 대하여 정상 상태에서의 해를 구하면서 수치적으로 실험하였다. 본 연구에서 얻어진 결론을 요약하면 다음과 같다. (1) 해석적으로 구하기 어려운 경사진 밀폐 공간에서 자연대류현상의 지배 방정식을 유한 차분법으로 해결할 수 있으며, 대류항과 확산항을 따로 고려한 유한차분법이 효과적임을 확인하였다. (2) 저온과 고온 벽면에서의 온도를 각각 균일하게 놓고 단변으로 이루어진 벽면은 완전히 절연되어 있는 경우에 대하여 수치해를 구한결과, 이전의 해석적 및 실험적 결과와 일치하였으며, 시간의 경과에 따른 온도 및 유선의 변화를 현상학적으로 관찰할 수 있었다. (3) 평균 열전달 계수에 미치는 경사각의 효과를 살펴본 결과 종횡비가 1 인 경우 경사각이 $45^{\circ}$에서, 종횡비가 2, 3, 5, 9인 경우 경사각이 $60^{\circ}$에서 각각 평균 열전달 계수 최대치가 나타났다. (4) Ra수(Rayleigh number) 가 증가될수록, 경사각에 상관없이 평균 열전달 계수도 증가되었다. 한편 Ra수 및 경사각의 변화에 따라 종횡비가 증가될수록 평균 열전달 계수는 경사각이 $90^{\circ}$인 경우를 제외하고는 감소됨을 볼 수 있었다. 경사각이 $90^{\circ}$인 경우, 평균 열전달 계수는 종횡비가 2 인 곳에서 최대치를 얻을 수 있었으며, 종횡비가 계속 증가될수록 평균 열전달 계수는 점차 감소되어짐을 볼 수 있었다.

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A Study on the role of Online Brand Community as an IMC Tool (통합적 마케팅커뮤니케이션 도구로써 온라인 브랜드 커뮤니티의 역할)

  • Kang, Yong Soo
    • Management & Information Systems Review
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    • v.29 no.4
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    • pp.123-142
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    • 2010
  • This study suggest that firms can use online brand communities as an IMC tool to achieve high brand loyalty through marketer-controlled or loyal customer-controlled brand contacts. In this perspective, the online brand community as a marketing communication tool can help the firm in eliciting favorable responses from customers. This study finds that an online brand community, as a critical marketing promotion tool, helps a firm elicit favorable relationship with customers and build strong brand loyalty. In particular, this study suggests several important theoretical and managerial implications. First, this study confirm that "advertising usefulness" is the most powerful and important factor that affects cgerial 's positive emotionomehile "sales promotion usefulness" impacmehin "interactivity" but dies not impacmhin "cgerial iexperience"ltyevent usefulness" impacmehin "cgerial iexperience"but dies not impacmhin "interactivity." In addition, "cgerial iexperience" signifn "itly impacmehin "cgerial -to-cgerial iinteractivity." This indicates that online environment provides participapacmwith a fun and exciting environment. In that sense, enhancing the online brand community experiencemwould be a critical factor for building strong brand. Thi", mword of mouth can play a riclly important role in making many cgerial s to trust brand and to enhance online brand community loyalty. Web users are becoming web authoore owning and creating content limited only by their imaginations.

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Expressional Characteristics of Interior Design Presented in Exhibition Spaces of Jean-Michel Wilmotte (장 미쉘 빌모트의 전시공간에 나타난 실내디자인 표현특성)

  • Song, Ga-Hyun;Kim, Moon-Duck
    • Korean Institute of Interior Design Journal
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    • v.23 no.6
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    • pp.87-94
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    • 2014
  • Today, the growing number of international architects enters the open market of South Korean architecture and interior from exhibition spaces such as art galleries to buildings of major companies. Establishing new local landmarks, their works have a considerable influence on the development of architecture. Among many, French architect Jean-Michel Wilmotte has worked consistently in South Korea. The purpose of this study is to analyze and put together the expression characteristic of the interior design in his exhibition spaces including Gana Art Gallery. Jean-Michel Wilmotte has designed based on the history, culture, society, and arts in France and other European countries, and is influenced by architects like Charles Rennie Mackintosh, Josef Hoffmann, and Carlo Scarpa. Such an influence is shown in the form of contrast between verticality and horizontality as well as the fortification in his modern classical characteristic, which is one of his expression characters. In his work of improving the ancient architecture, Wilmotte is good at creating a modern space through contextual expression, and the textural contrast between materials of the past and the present. Thus I performed an analysis of the expression characteristic of the interior design in National Museum of Contemporary Art of Chiado in Lisbon, Cognac Hennessy Museum in France, Gana Art Gallery in Korea, Mus$\acute{e}$e du Pr$\acute{e}$sident Jacques Chirac in Sarran, France, Ullens Center for Contemporary Art (UCCA) in Beijing, and lastly Mus$\acute{e}$e d'Orsay in Paris. The results show that he maintains the spatial context by applying contemporary design to the preserved existing structure, continues the flow of exhibition through the lightings in the corridors and on the ceiling, and seeks for a balance by adding vertical or horizontal elements to the elevation. In the interior, the staircase and exhibition structure are turned into objects, and the contrasting texture of the wall vitalizes the space. Wilmotte redesigns the space of the past and the present by using indirect joint that allows an organic connection of the old and new structures, and by minimizing the conflict between the two elements through prefabrication. The expression character of his interior design will be potential resources for architects and interior designers to develop their own design languages.

A Research on Political Engagement Index(PEI) Model about Election Strategy's Immersion in Candidate in Perspective of Engagement -Focusing on university students standard of selecting candidate in election for 18th president (인게이지먼트 관점에서 선거전략의 후보자 몰입에 관한 정치 인게이지먼트 모델(PEI)연구 - 제 18대 대통령 선거에서 대학생들이 후보자를 선택한 기준을 중심으로)

  • Kim, Man-Ki;Kim, Gyu-Hyun
    • Journal of Digital Convergence
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    • v.11 no.8
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    • pp.1-10
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    • 2013
  • Even though the importance of reading voters' share of mind increases in political campaign, there is no research which analyzes engagement in perspective of political campaign. Therefore, the purpose of this research is to calculate political engagement index which is qualitative indicator about political campaign's immersion in candidate in perspective of engagement and provide scientific data for political advertisement and publicity strategy. For this purpose, A and B candidates who ran for 18th president in December 19th, 2012 are selected for subjects of the research. The young people whose voter participations are low in this presidential election are selected as subjects for responding questionnaire and are surveyed. This research is qualitative evaluation which tires to supplement a limit of qualitative analysis of content by surpassing quantitative evaluation including advertisement, promotion, public opinion on politics, ratings, etc. Evaluation attribute is designed to distribute 8 PEI into 0~100 score. If PEI is more than 50, then the score indicates immersion above average. If PEI is lower than 50, then the score indicates immersion below average. The model of the research will contribute to development of methodological research of political campaign strategy. Also, in the future, this model can be used as micro-targeting in each political campaign's election strategy.

The Effect of Pervious Pavement on Reducing the Surface Runoff (투수성 포장재의 우수 표면유출 저감 효과)

  • Lee, Chun-Seok;Ryu, Nam-Hyung;Han, Seung-Ho
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.11 no.6
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    • pp.26-37
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    • 2008
  • The purpose of the study was to evaluate the effect of pervious pavements on reducing the surface runoff caused by rainfall. The surface runoff from twelve steel experimental beds with different pavement had been recorded every minute from May to September 2008, by the measuring system of tipping buckets(0.1mm/count) and data aquisition systems(National Instrument's Labview and DAQ boards & Autonics PR12-4). The dimension of the experimental bed was $1.5m(W){\times}2.0m(L){\times}0.6m(D)$ and eleven different kinds of vegetational(grass, grass+cubic stone, grass+hole brick), modular(brick, cubic stone, small cubic stone, wood block, interlocking block, clay brick, granular clay brick) and granular(naked soil, gravel) paving materials and concrete were applied for the comparison. Six rain events with depth over 30mm were selected and compared. The maximum depth of the rainfall selected was 137.5mm for 28 hours, and the minimum 30mm for 5 hours. The maximum rainfall per hour was 23mm/hr and the minimum 11.4mm/hr. The major findings were as follows; 1. All pervious pavement applied reduced over 75% of the surface runoff compared with concrete pavement. The grassy and porous pavements were relatively efficient in reducing surface runoff. 2. The grass was the more efficient as intercepting average 69.5mm of initial surface runoff, and maximum 77.8mm at the condition of 13.5mm/hr rainfall. The next was gravel intercepting maximum 65.5mm at the condition of 13.5mm/hr and the 40.9mm at 19.1mm/hr, average 55.7mm. 3. The modular pavements common in urban area were not good in intercepting the runoff except the 'clay granular brick' compared with others. The 'clay granular brick' showed relatively efficient intercepting average 14.1mm, which was the bigger amount than the 'grass+hole brick'. 4. The 'naked soil' were more effective than the 'concrete', 'brick', and 'interlocking block' in reducing the surface runoff, but less efficient than other materials. The capacity of the 'naked soil' to intercept the initial rainfall was similar to the 'brick'. As summary, the more grassy and porous pavement shows more effective in reducing surface runoffs.

A Study on the Needs for Development of the Community Services associated with Welfare Education (복지보육과 연계한 지역사회 서비스개발을 위한 욕구도 조사)

  • An, Eun Suk;Lee, Ji Young
    • Korean Journal of Childcare and Education
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    • v.2 no.1
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    • pp.17-40
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    • 2006
  • While the government has put forwards several programs associated with community services under a nursing guideline linking nursing facilities with community, few nursing facilities seem to make use of them effectively. In such a circumstance, this study was aimed at surveying parents' comprehensive and extensive needs for nursing services associated with community services, and thereupon, suggesting the ways for the successful nursing services meeting the needs from parents as well as community, and thereby, providing some data useful to development of the nursing services ensuring individual children's rights of being nursed as well as meeting the social needs. To this end, the researcher surveyed parents - with their children being cared by nursing facilities - for their life styles and their perception of community services. In this vein, the community services of nursing facilities were divided into four areas such as community services, community PR, engagement in community and use of community resources, and thereupon, current community service programs were analyzed to determine the differences among them depending on parents' needs and their demographic variables, and thereby, the effects of the community service programs on parents' comprehensive needs for community services were analyzed.

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