• Archives of Pharmacal Research
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• 제22권4호
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• pp.361-366
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• 1999

One of the potential causes of age-related neuronal damage can be reactive oxygen species (ROS), as the brain is particularly sensitive to oxidative damage. In the present study, we investigated the effects of aging and dietary restriction (DR) on ROS generation, lipid peroxidation, and antioxidant enzymes in cerebrum, hippocampus, and cerebellum of 6-, 12-, 18-, and 24-month-old rats. ROS generation significantly increased with age in cerebrum of ad libitum (AL) rats. However, no significant age-difference was observed in hippocampus and cerebellum. DR significantly decreased ROS generation in cerebrum and cerebellum at 24-months. On the other hand, the increased lipid peroxidation of AL rats during aging was significantly reduced by DR in all regions. Our results further showed that catalase activity decreased with age in cerebellum of AL rats, which was reversed by DR, although SOD activity had little change by aging and DR in all regions. In a similar way, glutathione (GSH) peroxidase activity increased with age in cerebrum of AL rats, while DR suppressed it at 24-months. These data further support the evidence that the vulnerability to oxidative stress in the brain is region-specific.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2010년도 학술발표회
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• pp.82-90
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• 2010

New Zealand appears to be a water rich country; however there are considerable water allocation issues. Mostly these revolve around balancing environmental concerns with economic development. The largest economic sector is agriculture which currently utilizes around 80% of the allocated water and has considerable potential to increase in size. The resource management framework that New Zealand has developed over the past twenty years revolves around local decision-making and sustainable management principles. As the demands for water have grown there has been growing concern that this framework is inadequate to deal with the issues of declining water quantity and quality through agricultural intensification. In Canterbury, the region with the highest water allocation and demand, a new approach is being trialed. The Canterbury Water Management Strategy (CWMS) recognizes the need for: ecological restoration for past damage; infrastructure development for increased irrigation; and the need to link infrastructure with more efficient use of water by both existing and new water users. These three elements are recognized as having equal value. The CWMS builds on the local decision-making concept but is deliberately aimed at consensus building in order to remove expensive and adversarial resource management hearings. It is practical enough to recognize that economic development is needed but that it need not proceed in conflict with the environment, but rather can be a means towards environmental improvement.

• Smart Structures and Systems
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• 제30권5호
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• pp.501-511
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• 2022

Three-dimensional (3D) models have become crucial for improving civil infrastructure analysis, and they can be used for various purposes such as damage detection, risk estimation, resolving potential safety issues, alarm detection, and structural health monitoring. 3D point cloud data is used not only to make visual models but also to analyze the states of structures and to monitor them using semantic data. This study proposes automating the generation of high-quality 3D point cloud data and removing noise using deep learning algorithms. In this study, large-format aerial images of civilian infrastructure, such as cut slopes and dams, which were captured by drones, were used to develop a workflow for automatically generating a 3D point cloud model. Through image cropping, downscaling/upscaling, semantic segmentation, generation of segmentation masks, and implementation of region extraction algorithms, the generation of the point cloud was automated. Compared with the method wherein the point cloud model is generated from raw images, our method could effectively improve the quality of the model, remove noise, and reduce the processing time. The results showed that the size of the 3D point cloud model created using the proposed method was significantly reduced; the number of points was reduced by 20-50%, and distant points were recognized as noise. This method can be applied to the automatic generation of high-quality 3D point cloud models of civil infrastructures using aerial imagery.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제50권2호
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• pp.110-115
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• 2024

A 22-year-old male patient presented to the clinic with severe pain in the preauricular area with an inability to completely occlude the jaw. Facial computed tomography and magnetic resonance imaging revealed a well-defined lesion that was tentatively diagnosed as a benign tumor or cystic mass. Surgical approach of a lesion in the condyle is delicate and problematic as many vulnerable anatomical structures are present. There are several methods for surgery in this area. Typically, an extraoral approach is dangerous because of potential injuries to nerves and arteries. The intraoral approach also presents difficulties due to the lack of visibility and accessibility. On occasion, coronoidectomy may be performed. The goal here was to determine an easier and safer new surgical approach to the condyle. We reached the anterior part of the pterygoid plate in the same method as in Le Fort I surgery. From this point, through the external pterygoid muscle, approaching the anterior aspect of the condyle is relatively easy and safe, with minimal damage to the surrounding tissues. Pus was drained at the site, and the lesion was diagnosed as an abscess. Pain and inability to close the mouth resolved without recurrence.

• The Plant Pathology Journal
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• 제40권3호
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• pp.272-281
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• 2024

Field surveys were conducted to assess the occurrence and diversity of plant-parasitic nematodes (PPNs) in golf courses and athletic fields across Maryland, USA, during 2022 and 2023. A total of 28 golf courses and ten athletic fields were surveyed, revealing the prevalence and abundance of 13 PPNs taxa in the region. Criconemoides was identified as the most prevalent (94.9%) and Tylenchorhynchus as the most abundant (2.3) across all samples. Central golf courses (west side of the Chesapeake Bay) exhibited a high prevalence of Criconemoides and Tylenchorhynchus, while Eastern Shore golf courses and athletic fields displayed a higher prevalence of Helicotylenchus and Criconemoides. Further, Belonolaimus longicaudatus was reported for the first time from turfgrass in Maryland, raising concerns due to its potential to cause severe damage on both cool- and warm-season turfgrass. Biodiversity analysis indicated that richness (R²) was higher in athletic fields, while diversity (H') and evenness (J') were significantly greater in golf courses. This study provides baseline information for monitoring PPNs distribution in Maryland and also for the development of effective nematode management approaches in turfgrass ecosystems.

• 한국환경보건학회지
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• 제40권5호
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• pp.355-366
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• 2014

Objectives: This study seeks to evaluate the vulnerability assessment of the human health sector for $PM_{10}$, which is reflected in the regional characteristics and related disease mortality rates for $PM_{10}$ in Busan over the period of 2006-2010. Methods: According to the vulnerability concept suggested by the Intergovernmental Panel on Climate Change (IPCC), vulnerability to $PM_{10}$ is comprised of the categories of exposure, sensitivity, and adaptive capacity. The indexes of the exposure and sensitivity categories indicate positive effects, while the adaptive capacity index indicates a negative effect on vulnerability to $PM_{10}$. Variables of each category were standardized by the rescaling method, and each regional relative vulnerability was computed through the vulnerability index calculation formula. Results: The regions with a high exposure index are Jung-Gu (transportation region) and Saha-Gu (industrial region). Major factors determining the exposure index are the $PM_{10}$ concentration, days of $PM_{10}{\geq}50$, ${\mu}g/m^3$, and $PM_{10}$ emissions. The regions that show a high sensitivity index are urban and rural regions; these commonly have a high mortality rate for related disease and vulnerable populations. The regions that have a high adaptive capacity index are Jung-Gu, Gangseo-Gu, and Busanjin-Gu, all of which have a high level of economic/welfare/health care factors. The high-vulnerability synthesis of the exposure, sensitivity, and adaptive capacity indexes show that Dong-Gu and Seo-Gu have a risk for $PM_{10}$ potential effects and a low adaptive capacity. Conclusions: This study presents the vulnerability index to $PM_{10}$ through a relative comparison using quantitative evaluation to draw regional priorities. Therefore, it provides basic data to reflect environmental health influences in favor of an adaptive policy limiting damage to human health caused by vulnerability to $PM_{10}$.

• 한국수자원학회논문집
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• 제52권10호
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• pp.753-761
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• 2019

여름철 집중호우는 도시지역의 홍수피해를 발생시키는 주요한 원인 중 하나이다. 우리나라의 최근 재해통계에 따르면 도시홍수의 발생빈도는 점점 잦아지고 있으며, 그 규모 또한 커지고 있다. 하지만 국지성 집중호우는 예측이 어려워 실제 홍수 대응을 담당하는 지자체 공무원들의 업무에 어려움이 있다. 따라서 본 연구에서는 이러한 도시홍수 대응에 시간적 여유 확보를 통한 피해 저감을 위해 앙상블 기상예측 자료를 활용한 홍수위험 매트릭스를 구축하고, 그 적용성을 판단하고자 하였다. 홍수위험 매트릭스는 홍수위험도의 정도를 나타내는 잠재적 영향(X축), 위험 기상현상이 발생할 확률인 발생가능성(Y축)으로 구성된 2차원 매트릭스로 확률예보에 기반한 홍수위험 예측 방안이다. 이를 위해 부산 및 대구광역시 내 기초지자체 각각 1곳을 대상으로 과거 홍수피해기록과 확률강우량 자료를 활용하여 지역별 홍수위험 매트릭스를 구축하고, 과거 호우사상에 대해 기상청의 LENS 자료를 적용하여 그 적용성을 판단하였다. 그 결과 최대 3일전 홍수위험에 대한 예측이 가능한 것으로 분석되었으며 실제 활용 시 홍수 대응시간을 확보하여 피해 저감에 도움이 되리라 판단된다.

• 해양환경안전학회:학술대회논문집
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• 해양환경안전학회 2007년도 추계학술발표회
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• pp.169-174
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• 2007

해상에서로 발생하는 대형 해양사고는 소중한 인명손상과 재산상의 손실 및 심각한 해양환경 오염피해를 유발하고 있다. IMO에서는 해양사고발생으로 인한 2차적인 해양환경오염피해 유발우려가 있는 선박을 적절히 이동시켜 잠재적인 해양사고 발생가능성 및 피해를 최소화하기 위한 적절한 장소(피난처)에 대한 논의가 활발하게 전개되고 있는 상황이다. 우리나라는 북태평양을 중심으로 아시아지역과 북미를 연결하는 주요 통항로에 위치하여 선박 통항량이 많기 때문에 외국적 조난선박에 의한 해양사고 발생가능성이 높으며, 또한 국내 항에서 발생하는 해양사고에서도 선박의 이동이 필요한 경우 안전한 장소로 이동시켜 해양사고로 인한 2차 피해를 최소화 할 필요성이 있다. 본 연구에서는 선박피난처 지정에 대한 외국사례를 검토 분석하여 효율적이고 합리적인 국내 피난처 도입방안을 마련하고자 하였다.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• 제61권11호
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• pp.573-579
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• 2018

Background and Objectives Cochlear dead region (CDR) is a region in the cochlear where hearing loss has occurred due to damage to the inner hair cells and/or neurons. Recently, a subjective test involving a pure-tone test in the presence of threshold-equalizing noise (TEN) was introduced to identify CDR. However, for uncooperative patients, such a subjective method would be unsuitable and objective methods would be needed instead to detect CDR. The acoustic change complex (ACC) is an evoked potential elicited by changes in the ongoing sound. In this study, we developed an objective method of identifying CDR by combining ACC response with a TEN test, namely the TEN-ACC test, and investigated its feasibility in normal-hearing listeners. Subjects and Method Ten normal-hearing subjects participated in this study. All subjects underwent both behavioral TEN test and electrophysiological TEN-ACC test. The stimuli for the TEN-ACC test consisted of TEN and embedded pure tones with different frequencies/signals to noise ratios (SNRs). To identify the thresholds, the range SNR of stimulation was varied from 0 to 20 dB, in stages of 4 dB. Results The ACC responses of all subjects who participated in this study were well elicited by stimuli developed for the TEN-ACC test. We confirm that the pure-tones embedded in TEN elicited the objective ACC response. Conclusion The results of this study suggest that the novel TEN-ACC test can be applied to evoke ACC in normal-hearing listeners. Future research should incorporate hearing-impaired listeners to determine the feasibility of the TEN-ACC test as an objective method to identify CDR.

• 생태와환경
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• 제52권4호
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• pp.306-315
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• 2019

한강 하구는 오염물질과 병원성 미생물의 유입 및 확산 가능성으로 인해 이곳에 서식하는 수산생물에 피해가 발생할 수 있다. 하지만 지금까지 이 지역 서식 생물에 대한 법정전염병 병원체 감염 여부가 조사된 자료는 찾아보기 힘들다. 본 연구에서는 한강 하구 전류리에 서식하는 수산 생물 중 잉어과 어류와 갑각류를 대상으로 법정전염병(잉어봄바이러스병, SVC; 잉어허피스바이러스병, KHVD; 유행성궤양증후군, EUS; 흰반점병, WSD) 및 기생충의 감염 여부를 조사하였다. 전류리 유역에서 채집된 어류는 잉어과 어류가 가장 많았으며 주연성 어류와 일차 담수어가 같이 관찰되었고, 갑각류는 해산종이 채집되었다. 채집된 잉어과 어류와 갑각류에 대해 PCR을 이용한 법정전염병 검사 결과 이들 질병에 감염된 개체는 없었다. 기생충성 질병 검사 결과 공중보건상 위협요인인 간흡충이 검출되지는 않았지만 일부 어류에서 다른 흡충류의 metacercaria와 nematode, cestode, copepod, 단생충 및 구두충 등의 감염을 확인할 수 있었다. 이상의 결과는 아직 한강 하구가 주요 수산생물 전염병 병원체에 심각하게 오염되지 않았음을 의미한다. 그러나 한강의 수질 상태는 지속적으로 변화하고 수서 생태계에 대한 전염병의 파괴력은 예측하기 힘들 정도로 위험하므로, 지속적인 방역 노력이 진행되어야 할 것이다. 이를 위해 조사 지역을 전류리뿐만 아니라 이곳보다 상류로 확대하고 조사 개체 수를 늘려서 질병모니터링을 실시할 필요성이 제기된다.