• 한국식품위생안전성학회지
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• 제32권1호
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• pp.70-74
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• 2017

해양생물자원은 차세대 바이오산업의 중요한 자원으로 관심이 증대되고 있다. 다양한 해양생물자원이 생물학적 활성을 가지고 있을 것으로 기대됨에도 불구하고, 지금까지는 시료 채취의 어려움 등으로 개발에 제한이 있었다. 해면동물, 해조류, 산호 등의 대부분의 해양생물자원들이 험난한 환경에서 살아남기 위해 특수한 대사산물을 만들어 낼 것으로 여겨지고 있어 이를 활용하기 위한 노력들이 기울여지고 있다. 많은 종류의 해양생물자원 중에서 바이오산업에 활용할 수 있는 항암, 항균, 항바이러스 및 항암 작용 등과 같은 생물학적 활성을 가진 물질을 선별하는 것이 시급한 실정이다. 본 연구에서는 항암 작용을 갖는 해양생물자원을 도출하기 위하여 사람유래 대장암 세포주에서 세포독성시험을 실시하였다. 해양생물자원은 2013년 3월 마크로네시아에서 채취한 샘플들로 메탄올로 추출한 물질을 사용하였다. 해양생물자원의 세포독성시험을 실시하여 20개의 시료 중에서 3개의 시료에서 농도의존적인 세포 생존을 억제하는 것을 확인하였다. 검색된 시료들 중 2종만이 동정되어, 해면동물 Hyrtios sp.임이 밝혀졌다. 한종은 아직 밝혀지지 않은 상태로 추가적인 연구를 통해 동정이 필요하였다. Hyrtios sp. 추출물(1304KO-327과 1304KO-329)의 HCT116세포 증식억제작용은 이전 연구에서 보고된 RKO에서의 작용과 일치함을 알 수 있었다. 대장암세포주의 생존 억제 활성을 밝혀낸 3종의 도출 물질은 앞으로의 지속적인 연구를 통해 추출물 중의 항암 활성 물질을 규명함으로써 바이오산업의 새로운 개발 자원으로 활용될 것이 기대된다.

• Journal of Microbiology and Biotechnology
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• 제30권5호
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• pp.649-661
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• 2020

This study examined the laxative effects of hot-water extracts of Hovenia dulcis Thunb. (HD), Phyllostachys pubescens Mazel (PM), and a 2:8 mixture of both (HP) in two chronic constipation models. For the loperamide-induced constipation model, animals were divided into an untreated group, negative control group (loperamide 4 mg/kg), positive control group (bisacodyl 4 mg/kg) group, and six treatment groups (HP 100 or 400, HD 50 or 100, and PM 100 or 400 mg/kg). For the low-fiber diet-induced constipation model, animals were divided into an untreated group (normal diet), negative control group (low-fiber diet), positive control group (Agio granule, 620 mg/kg), and the same treatment groups. Fecal number, weight, fecal water content, and intestinal transit ratio were higher in the groups treated with HP, HD, and PM than in the groups treated with loperamide or low-fiber diet. Thickness of colon mucosa and muscle layers were increased in the treated groups. Colon tension increased in the HP groups, and [Ca²⁺]i measurements using fura-2 as an indicator showed that HP inhibits ATP-mediated Ca²⁺ influx in IEC-18 cells. These results showed that the HP mixture has laxative activity by increased mucin secretion and inducing contractile activity and relaxation. It may be a useful therapeutic strategy for ameliorating in chronic constipation.

• KDI Journal of Economic Policy
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• 제32권1호
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• pp.51-68
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• 2010

본 연구는 가계 내 경제적 자원이 자녀의 건강에 미치는 영향을 분석한다. 경제적 자원과 건강 간의 관계는 두 변수 상호 간의 영향으로 인해 분석이 용이하지 않다. 그러나 성인의 건강이 노동공급 등을 통해 경제적 자원에 영향을 미치는 것과는 달리, 자녀의 건강은 경제적 자원에 미치는 영향이 적으므로 가계의 경제적 자원이 자녀의 건강에 미치는 영향은 분석이 상대적으로 용이하다. 인도네시아 자료(Indonesian Family Life Survey)를 이용하여 분석한 결과, 가계의 경제적 자원이 자녀의 건강에 통계적으로 유의한 수준에서 긍정적인 영향을 끼치는 것으로 나타났다. 또한 경제적 자원이 자녀의 건강에 영향을 끼치는 경로는 영양상태, 의료서비스의 이용, 가계의 위생상태 등인 것으로 나타났다. 따라서 저소득 가구 자녀의 건강증진을 위해서는 의료서비스의 이용 증대뿐만 아니라 가구의 위생상태 등을 개선하는 정책 또한 중요한 것으로 판단된다.

• Journal of Information Science Theory and Practice
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• 제11권3호
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• pp.1-15
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• 2023

The present study examines the impact of value co-creation on satisfaction and intention to adopt of e-resources among users. Four components of the DART model have been adopted to describe value co-creation. These components are dialogue, access, risk-assessment, and transparency. Ph.D. scholars and faculty members from National Capital Region, India, were requested to respond on a five-point Likert scale. A total of 220 responses were collected with the help of a structured questionnaire from respondents of the top 50 business schools according to National Institute Ranking Framework. These responses have been analysed by means of structured equation modelling on Adanco 2.2 software. Findings of the study reported the insignificant impact of access and risk-assessment, and positive impact of dialogue and transparency on satisfaction. Further, satisfaction has been identified, creating significant impact on adoption of e-resources. Such findings reflect the real picture of customer experience with respect to their role in co-creation of e-resources. Respondents have conveyed their dissatisfaction with the co-creation process of e-resources, as companies do not provide all the information and access to their customers beforehand. Consequently, customers fail to make informed decisions and also find themselves unable to show trust in the service providers of e-resources.

• 가정과삶의질연구
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• 제19권1호
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• pp.191-203
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• 2001

The purpose of this study is to find out the relationship among the identity, lifestyle and satisfaction with family resources of rural married persons. The subjects of this study were 435 married women and men in Ansung. The major findings were as follows: 1. The identity of rural married persons was significantly different depending on their gender and educational level. 2. Their lifestyle was significantly different depending on their gender, educational level, job, the type of dwelling, and family income. 3. Their satisfaction with family resources was significantly different depending on their educational level, job, the type of dwelling, and family income. 4. There was positive correlation among their identity, lifestyle and satisfaction with family resources of the rural married persons.

• 한국수산과학회지
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• 제53권5호
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• pp.790-793
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• 2020

Length-weight relationships (LWR) for 27 fish species inhabit Southern sea in Korea were investigated to describe several biological characters. Total 7,399 individuals were collected by R/V Tamgu-20 using bottom trawl between 2018 to 2019 and were identified as 19 families and 27 species. Parameter b ranged from 2.414 to 3.472. Thirteen species among 27 species showed isometric growth (b=3), six species showed negative allometry (b<3) and eight species showed positive allometry (b>3). The results of this study provide useful basic biological information about 27 fishes and are highly reliable due to use of data measured directly.

• International Journal of Industrial Entomology and Biomaterials
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• 제13권2호
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• pp.113-117
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• 2006

Heterosis was studied involving two multivoltine silkworm breeds viz, APM1 and SLKSPM through rearing and isozyme analysis. A positive significant heterotic effect was observed in fecundity, hatching % and survivability. The heterobeltiosis was observed only in fecundity and hatching %. Isozyme analysis of ${\alpha}-esterase$ showed variation in loci and allelic expression. The allele with heterozygosity $(Est-2^{12})$ was observed at the Est-2 locus in $F_1$ progeny. Est-3 was observed in $F_1$ progeny, whereas it was completely absent in both parental lines. The present study suggests that the markers ($Est-2^{12}$ and Est-3) targeted for introgression may be useful for the improvement of fecundity and survivability as the phenomenon of heterosis was observed only in $F_1$ progeny.

• 가정과삶의질연구
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• 제2권1호
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• pp.79-92
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• 1984

The purpose of this study is to identify family stress and to specify family stress and socio-psychological resources which are associated variable. For the evidence of this topic, research was conducted on 258 married persons dwelling in seoul. The questionnare was composed of Family Stressor Inventory referred by McCubbin's FILE(1981) and Sarason's LES(1979) and Socio-Psychological Family Resources Inventory referred by McCubbin's FIRM(1983). This study offers to us that family income significantly has positive correlation with socio-psychological family resources and family income is potential variable which intensifies family tension or burden. This study touched only some variables, moreover, this is only a starting-point of family stress study in Korea. So further studies would consider latent variables, process, limited situation, family interaction pattern, family orientation, etc., and subjective variables would be reflected.

• 한국산림과학회지
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• 제96권2호
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• pp.145-150
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• 2007

This study was conducted to elucidate the mid-growth of Norway spruce at the age of 27 and select the superior provenances in Korea. Growth performance of twenty-four provenances from Germany and Rumania were investigated in four plantations. Significant differences were found in growth (height, DBH, volume) with plantations. Maximum growth were detected on plantation Chuncheon which located in most northern area, and minimum growth were detected on plantation Wanju located in most southern area. The rank of height in provenances has fluctuated, but superior/inferior groups have been almost fixed. 840-23, 840-10, 840-19 in Germany, G1-64-57, G1-64-54 in Rumania proved excellent provenances. Height in early stage positively correlated with that in late stage. The growth was positively correlated with latitude and altitude of plantations, but negatively correlated with temperature.

• Journal of Animal Science and Technology
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• 제64권5호
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• pp.1008-1011
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• 2022

We here report the whole genome sequence of Ligilactobacillus agilis C7 with anti-listerial activity, which was isolated from pig feces. The genome size of L. agilis C7 (~ 3.0 Mb) is relatively larger compared with other L. agilis strains. L. agilis C7 carries three bacteriocin gene clusters encoding garvicin Q, salivaricin A, and Blp family class II bacteriocin. Garvicin Q and salivaricin A are reported to be active against Listeria monocytogenes and Micrococcus luteus, respectively, as well as against other Gram-positive bacteria. Meanwhile, the bacteriocin encoded in the blp cassette was shown to be active against pneumococci, mediating intraspecies competition. This report highlights the potential of L. agilis C7 for the production of bacteriocins inhibiting pathogenic bacteria.