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http://dx.doi.org/10.5187/jast.2022.e55

Whole genome sequence analysis of Ligilactobacillus agilis C7 isolated from pig feces revealed three bacteriocin gene clusters  

Jeong Min, Yoo (Department of Animal Resources Science, Dankook University)
Remilyn M., Mendoza (Department of Animal Resources Science, Dankook University)
In-Chan, Hwang (Department of Animal Resources Science, Dankook University)
Dae-Kyung, Kang (Department of Animal Resources Science, Dankook University)
Publication Information
Journal of Animal Science and Technology / v.64, no.5, 2022 , pp. 1008-1011 More about this Journal
Abstract
We here report the whole genome sequence of Ligilactobacillus agilis C7 with anti-listerial activity, which was isolated from pig feces. The genome size of L. agilis C7 (~ 3.0 Mb) is relatively larger compared with other L. agilis strains. L. agilis C7 carries three bacteriocin gene clusters encoding garvicin Q, salivaricin A, and Blp family class II bacteriocin. Garvicin Q and salivaricin A are reported to be active against Listeria monocytogenes and Micrococcus luteus, respectively, as well as against other Gram-positive bacteria. Meanwhile, the bacteriocin encoded in the blp cassette was shown to be active against pneumococci, mediating intraspecies competition. This report highlights the potential of L. agilis C7 for the production of bacteriocins inhibiting pathogenic bacteria.
Keywords
Ligilactobacillus agilis; Genome; Bacteriocin; Anti-listerial;
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