• Title/Summary/Keyword: Point of Delivery

Search Result 445, Processing Time 0.04 seconds

Network-Based Partially-Distributed Mobility Management Mechanism and Performance Evaluation (망기반 부분분산형 이동성 관리 메커니즘 및 성능분석)

  • Ki, Jang-Geun;Lee, Kyu-Tae
    • The Journal of the Institute of Internet, Broadcasting and Communication
    • /
    • v.14 no.6
    • /
    • pp.75-84
    • /
    • 2014
  • In order to solve the problems such as overload, single point of failure, non-optimized data path, and network scalability in conventional central mobility management protocols, distributed mobility management schemes have been continually studied in and around the IETF. In this paper, a network-based partially-distributed mobility management mechanism, pDMMv6, is suggested and the performance comparison with traditional protocols such as PMIPv6 and MIPv6 is made through simulation under the various user traffic environment. The simulation results include UDP packet delivery ratio, end-to-end packet delay, binding delay for registration signaling, CPU utilization in each node, and response delays in several server-client TCP applications such as web browsing, e-mail, telnet remote login, FTP file up/down-load, and database access.

The Prediction of the Apartment Construction Project Cashflow with Changing Sales Point (분양시기 변동에 따른 공동주택 건설공사 현금흐름 예측)

  • Bae Jun-Ho;Kim Jae-Jun
    • Proceedings of the Korean Institute Of Construction Engineering and Management
    • /
    • autumn
    • /
    • pp.234-237
    • /
    • 2003
  • The Korean housing supply have been provided by the Pre-construction sales system. The Pre-construction sales system contributed to large housing supply. But it followed by the market anomaly. Along the housing market is changing to tile market for consumers, it requires new policy and regulations. This market changes and needs to modify the policy make a discussion about introducing the Post-construction sales system. it concerns to change the time to sale. This paper analyzes the present feasibility study and makes a tool to predict construction cashflow considering changed sales point. The sales timing leads to decide the amount of financial costs in the construction project and that cost affects to the feasibility. The accurate cashflow prediction is required for a successful apartment construction delivery.

  • PDF

Robotics for Advanced Therapeutic Colonoscopy

  • Wong, Jennie YY;Ho, Khek Yu
    • Clinical Endoscopy
    • /
    • v.51 no.6
    • /
    • pp.552-557
    • /
    • 2018
  • Although colonoscopy was originally a diagnostic imaging procedure, it has now expanded to include an increasing range of therapeutic interventions. These procedures require precise maneuvers of instruments, execution of force, efficient transmission of force from the operator to the point of application, and sufficient dexterity in the mobilization of endoscopic surgical instruments. The conventional endoscope is not designed to support technically demanding endoscopic procedures. In case of colonoscopy, the tortuous anatomy of the colon makes inserting, moving, and orientating the endoscope difficult. Exerting excessive pressure can cause looping of the endoscope, pain to the patient, and even perforation of the colon. To mitigate the technical constraints, numerous technically enhanced systems have been developed to enable better control of instruments and precise delivery of force in the execution of surgical tasks such as apposing, grasping, traction, counter-traction, and cutting of tissues. Among the recent developments are highly dexterous robotic master and slave systems, computer-assisted or robotically enhanced conventional endoscopes, and autonomously driven locomotion devices that can effortlessly traverse the colon. Developments in endoscopic instrumentations have overcome technical barriers and opened new horizons for further advancements in therapeutic interventions. This review describes examples of some of these systems in the context of their applications to advanced therapeutic colonoscopy.

Filling of Cu-Al Alloy Into Nanoscale Trench with High Aspect Ratio by Cyclic Metal Organic Chemical Vapor Deposition

  • Moon, H.K.;Lee, S.J.;Lee, J.H.;Yoon, J.;Kim, H.;Lee, N.E.
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 2012.02a
    • /
    • pp.370-370
    • /
    • 2012
  • Feature size of Cu interconnects keep shrinking into several tens of nanometer level. For this reason, the Cu interconnects face challenging issues such as increase of electro-migration, line-width dependent electrical resistivity increase, and gap-filling difficulty in high aspect ratio structures. As the thickness of the Cu film decreases below 30 nm, the electrical resistivity is not any more constant, but rather exponential. Research on alloying with other elements have been started to inhibit such escalation in the electrical resistivity. A faint trace of Al added in Cu film by sputtering was reported to contribute to suppression of the increase of the electrical resistivity. From an industrial point of view, we introduced cyclic metal organic chemical vapor deposition (MOCVD) in order to control Al concentration in the Cu film more easily by controlling the delivery time ratio of Cu and Al precursors. The amount of alloying element could be lowered at level of below 1 at%. Process of the alloy formation was applied into gap-filling to evaluate the performance of the gap-filling. Voidless gap-filling even into high aspect ratio trenches was achieved. In-depth analysis will be discussed in detail.

  • PDF

A Study on Space Expression According to the Production Characteristics of Reflex Media (영상미디어 연출 특성에 따른 공간 표현에 관한 연구)

  • Yoo Jae-Yeup
    • Korean Institute of Interior Design Journal
    • /
    • v.13 no.6
    • /
    • pp.175-183
    • /
    • 2004
  • As the information-oriented society makes progress, the role of Image has much influence on human being in space as a medium for information delivery and a means of artistic communication. These influences are appeared as expressional characteristics of the image such as the reproducibility of reality and unreality in the real world, the synchrony of expression of time, visual formality, a sign and the transmission of moaning. For these, the investigator examined the meaning of image in aspace, taking into consideration of the interrelationship of image, space, and human being. As study findings show, the expressional characteristics of image in space have such visual effects as a space in which pictorial formality and object exists, in which the mutual understanding of communication exists, and that realizes immaterial membrane in the aspect of time and space, according to the electronic light, color, and formation of the image media. In addition, it become clear that the characteristic could be staged on various circumstances by constructing the relationship between an object and a point of time interactively with bidirectional communication through combining technology and art. This suggests that the image develops as the form of sensory communication via interacting of space and human being.

Controlled Release and Stabilization of Cefaclor from Alginate-based Matrices for Oral Delivery Design

  • Bak, So-Im;Lee, Jue-Yeon;Song, Hye-Won;Hwang, Jeong-Hyo;Lee, Seung-Jin
    • Journal of Pharmaceutical Investigation
    • /
    • v.32 no.4
    • /
    • pp.327-330
    • /
    • 2002
  • Alginate based polymeric matrices were designed for controlled release and stabilization of cefaclor in gastrointestinal fluid. Cefaclor is known to be acid stable and subjected to be degraded at neutral and alkaline pHs. In order to achieve an effective release profile of cefaclor in gastrointestinal tract, a particular strategy in dosage form design should be required from the view point of maintaining its activity. The amphiphilic nature of cefaclor allowed its controlled release using ionic polymers based on ionic interaction between the drug and polymers. The thrust of this study was to develop a technique that delivers cefaclor keeping effective release rate in the intestinal tract. Considering the fast degradation of cefaclor in the intestinal fluid, the matrices were designed to release surplus amount of cefaclor. The alginate based matrices demonstrated increase in release rate in the simulated intestinal fluid, which was favorable to compensate the degraded portion of cefaclor. In addition, stabilization of cefaclor in the intestinal fluid was obtained by employing citric acid that provides an local acidic environment. The matrices might be valuably used for the development of an oral cefaclor dosage form.

Development and Evaluation of an Elementary School Nutrition Education Program to Prevent Breakfast Skipping (아침결식 예방을 위한 초등학교 영양교육 프로그램의 개발 및 평가)

  • Son, Hyeong-Gyeong;Lee, Yeon-Kyung
    • Korean Journal of Community Nutrition
    • /
    • v.15 no.6
    • /
    • pp.740-749
    • /
    • 2010
  • The purpose of this study was to develop and evaluate a nutrition education program to prevent breakfast skipping for elementary school children. Subjects were 102 5th grade students (51 boys, 51 girls) as the "education group" and 200 5th grade students (102 boys, 98 girls) as the "non-education group." The nutrition education program consisted of 4 lessons over an 8-week period. Teaching materials, including flash animation, panel, PowerPoint, and a bingo game, were developed for this education program. After education, there was significant increase in the percentage of students who had eaten breakfast every day, understood that breakfast has a great effect on health, and will eat breakfast every day in the education group compared to non-education group. Parents' positive behavior toward daily breakfast preparation and the percentage of parents who had their children eat breakfast every day increased significantly. The students of the education group responded positively to the questions of the benefit and importance of nutrition education. The flash animation received high marks, especially in terms of understanding of contents, content clarity, emphasis of the core content, delivery of necessary knowledge, and applicability of breakfast. This study shows the effectiveness of a 4-lesson nutrition education taught during an 8-week time period to induce changes in recognizing the importance of breakfast and in behavior toward breakfast consumption.

The Quality Control of Adlay Tea and Wheat Noodles Served from the Vending Machines Based on the Periods of Storage (자동판매기에서 판매되는 율무차와 우동의 저장기간에 따른 품질평가(II))

  • 김혜영;이경연;김지영
    • Korean journal of food and cookery science
    • /
    • v.15 no.2
    • /
    • pp.171-177
    • /
    • 1999
  • The purpose of this study was to serve a standard of the good quality control and shelf-life of food and beverage served from the vending machines. So it was performed to examine the temperature (internal & external environmental, food itself), pH, Aw, POV and microbiological quality of Adlay tea and Wheat noodles served from the vending machines based on storage time in the machines. They were assessed to find the critical control point(CCP) during each of the production, delivery, purchasing phases from the vending machines. The result of this study can be summarized as follows: 1. The temperature of foods inside the vending machines was ranged from 4$0^{\circ}C$ to 45$^{\circ}C$. It was in the range of dangerous zone. The average temperature of food showed 71$^{\circ}C$ for Adlay tea and 74$^{\circ}C$ for Wheat noodles. As a result of measuring pH and Aw, they had potential danger. 2. Even though POV was low, it increased as the time passed. 3. As a result of microbial analysis, it showed that the amount of total plate count and coliforms were increased ten times after 1 day respectively. Wheat noodles' coliform and total plate counts exceeded standard value in 1 day. As a result of food poisoning bacteria, it was negative in sample against Vibrio parahaemolyticus, Salmonella, Staphylococcus aureus.

  • PDF

Application of Stem Cells in Targeted Therapy of Breast Cancer: A Systematic Review

  • Madjd, Zahra;Gheytanchi, Elmira;Erfani, Elham;Asadi-Lari, Mohsen
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.5
    • /
    • pp.2789-2800
    • /
    • 2013
  • Background: The aim of this systematic review was to investigate whether stem cells could be effectively applied in targeted therapy of breast cancer. Material and Method: A systematic literature search was performed for original articles published from January 2007 until May 2012. Results: Nine studies met the inclusion criteria for phase I or II clinical trials, of which three used stem cells as vehicles, two trials used autologous hematopoetic stem cells and in four trials cancer stem cells were targeted. Mesenchymal stem cells (MSCs) were applied as cellular vehicles to transfer therapeutic agents. Cell therapy with MSC can successfully target resistant cancers. Cancer stem cells were selectively targeted via a proteasome-dependent suicide gene leading to tumor regression. $Wnt/{\beta}$-catenin signaling pathway has been also evidenced to be an attractive CSC-target. Conclusions: This systematic review focused on two different concepts of stem cells and breast cancer marking a turning point in the trials that applied stem cells as cellular vehicles for targeted delivery therapy as well as CSC-targeted therapies. Applying stem cells as targeted therapy could be an effective therapeutic approach for treatment of breast cancer in the clinic and in therapeutic marketing; however this needs to be confirmed with further clinical investigations.

BIM based Construction Project Case Analysis for Facility Life Cycle Management from the Perspective of the Client (발주처 관점의 시설물 생애주기 관리를 위한 BIM 기반 건설 프로젝트 사례 분석)

  • Ham, Nam-Hyuk;Kim, Woong-Gi;Kim, Jae-Jun
    • Journal of KIBIM
    • /
    • v.10 no.3
    • /
    • pp.12-21
    • /
    • 2020
  • From the perspective of the client, the value of information for use in facility management is very low at the point of use. This is because the facility owner, who is a non-professional, cannot accurately request necessary information from the perspective of long-term facility life cycle management. The purpose of this study is to define the information necessary for facility management and to analyze the project operation method to procur this information to the client using BIM. To this end, this study analyzed the role of client and contractor, project delivery process, standards, and submissions in the BIM-based procurement area through USACE Air Force Hospital project case analysis. As a result of the analysis, if the client, who is the subject of facility operation, defines in advance the type and input method of necessary information in the operation stage, the client can receive the BIM optimized for operation from the contractor. The results of this study can be used to establish standards for receiving information necessary for establishment of procurement process and facility management of public institutions considering BIM introduction.