• The Journal of Korean Academy of Sensory Integration
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• v.19 no.1
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• pp.1-12
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• 2021

Objective : The purpose of this study was to investigate the effects of paired-group sensory integration therapy on sensory processing, peer interaction, and play development of four-year-old children. Methods : This study involved 13 weekly sessions of a four-minute intervention as well as an initial 10 minutes of parental counseling for those without experience of paired-group sensory integration therapy. The intervention consisted of sensory processing activities and various occupational activities, and the children's Short Sensory Profile (SSP), Penn Interactive Peer Play Scale (PIPPS), and Knox Preschool Play Scale-Revised (KPPS-R) were measured before and after the sessions for comparison. The results are presented using visualized data. Results : After the paired-group interventions, all subjects showed improved sensory processing ability according to their SSP scores and improved play development on the KPPS-R. Moreover, the frequency of negative interactions decreased in the PIPPS measure. Conclusion : This paired-group sensory integration therapy had a positive effect on sensory processing, peer interaction, and play for children with developmental delay. In the future, research that applies this kind of paired-group intervention in various age groups would be useful.

• Journal of Acupuncture Research
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• v.26 no.3
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• pp.19-26
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• 2009

Objectives : The purpose of this study is to introduce oriental medicine music therapy during the acupuncture of pathogenic fire. Methods : We investigated the acupuncture points of pathogenic fire and the methodology of oriental medicine music therapy. Results : During the acupuncture of pathogenic fire, patients listen to proper music and after withdrawing of acupuncture, patients play the musical instrument. The patients with the case of fire due to affection by exopathogen, the method of dispelling superficial fire can be used through playing percussion instruments. The case of patients with the fire of five organ, the Five Phases music can be used properly. Conclusions : This study describes oriental medicine music therapy has a good possibility as a treatment of pathogenic fire with acupuncture.

• The Journal of Korea Robotics Society
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• v.17 no.4
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• pp.447-454
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• 2022

This paper presents the psychomotorik-based play activities executed by the social robot at home which helps children's social and emotional development. Based on the theory and practice of the psychomotorik therapy, the play activities were implemented in the close collaboration between psychmotorik experts, service designers and robotics engineers. The designed play activities are classified into four categories depending on the main areas of child development. The robotic system that can express verbal and nonverbal behaviors was developed in order to play games with children and but also to make children have continuous interest during the play activities with it. Finally, the psychomotorik-based play service scenario and interactive robot system were validated by the expert group from the domain of child psychotherapy. The evaluation results showed that the play service and the robot system were appropriately developed for children from the experts point of view.

• Physical Therapy Korea
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• v.3 no.2
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• pp.84-94
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• 1996

This paper reviews physiological changes in the nervous system of patients with hemiparesis that may contribute to muscle weakness. The discussion includes the important role that alterations in the physiology of motor units, notably changes in firing rates and muscle fiber atrophy, play in the manifestation of muscle weakeness. This role is compared with the lesser role that spasticity of the antagonist muscle group appears to play in determining the weakness of agonist muscles. The contribution of other factors that result in mechanical restraint of the agonist by the antagonist is discussed relative to muscle weakness in patients with hemiparesis. More studies on patients with hemiparesis are required to assess what role muscle strength training should play in rehabiliting patients after a stroke.

• Journal of Convergence for Information Technology
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• v.10 no.3
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• pp.176-184
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• 2020

The purpose of this study was to investigate whether group play therapy is effective in reducing problem behaviors of children with developmental disabilities. The subjects of study were in special schools and 5 children with disabilities using short-term care centers for the disabled, The research period was 12 sessions of 40 minutes twice a week using winter vacation from January 2, 2018 to January 28, The measuring tool, K-CBCL, was used to observe behavioral changes qualitatively. The summary of this study is as follows. First, children with disabilities significantly reduced their aggressiveness, atrophy, depression, and anxiety, and increased their activity during each session. Second, problem behaviors decreased after the intervention of group play therapy, and there were more decreases in internalization problems than externalization problems. The results of this study suggest that group play therapy is meaningful in reducing problem behavior according to the individual characteristics of children with disabilities.

• BMB Reports
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• v.52 no.1
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• pp.35-41
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• 2019

Cellular senescence, a permanent state of cell cycle arrest, is believed to have originally evolved to limit the proliferation of old or damaged cells. However, it has been recently shown that cellular senescence is a physiological and pathological program contributing to embryogenesis, immune response, and wound repair, as well as aging and age-related diseases. Unlike replicative senescence associated with telomere attrition, premature senescence rapidly occurs in response to various intrinsic and extrinsic insults. Thus, cellular senescence has also been considered suppressive mechanism of tumorigenesis. Current studies have revealed that therapy-induced senescence (TIS), a type of senescence caused by traditional cancer therapy, could play a critical role in cancer treatment. In this review, we outline the key features and the molecular pathways of cellular senescence. Better understanding of cellular senescence will provide insights into the development of powerful strategies to control cellular senescence for therapeutic benefit. Lastly, we discuss existing strategies for the induction of cancer cell senescence to improve efficacy of anticancer therapy.

• Journal of Music and Human Behavior
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• v.9 no.2
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• pp.53-67
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• 2012

Improvisational music therapy is known to promote social engagement in children with autism. This study investigated salient features that characterize the engagement of the child with autism and the therapist in improvisational music therapy. Through video analysis of the children's behavior, this study sets out to investigate what engages children with autism into mutual play with the therapist in improvisational music therapy by measuring the shared musical elements between the child and the therapist during musical synchronicity episodes and the children's choice of instruments. A repeated measures, a crossover design was employed in two different conditions (n = 10). Children were randomly assigned into two groups; group 1 participated music therapy first, followed by play therapy second. Group 2 followed the reverse order. Specific target behaviors were analyzed in the selected sessions 1, 4, 8 and 12. As expected, improvisational music therapy produced markedly more and longer events of musical synchronicity in children with autism than the play sessions with toys (p < .001). Rhythm and dynamic appeared to be the two most salient elements during musical synchronicity events between the child and the therapist. Observational findings confirmed that horns and whistles were the most frequently selected instruments in music therapy, whereas a dollhouse set was in play therapy by children with autism. The clinical implications and the details of these findings are discussed further.

• Journal of Music and Human Behavior
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• v.17 no.1
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• pp.51-70
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• 2020

The purpose of this study was to examine the effects of group music therapy involving the creation of a musical play on the self-esteem, self-expression, and social skills of children. The participants were 14 first through third graders and 14 fourth through sixth graders from a children's center. Half of the children from each grade band (Grades 1-3 and 4-6) were assigned to the experimental group and the other half to the control group, for a total of 14 children in each group. The experimental group who participated in music therapy sessions focused on creating a musical play. The experimental group selected themes, made a script, composed song lyrics and music, and performed the completed musical play. The Self-Esteem Scale, Self-Expression Scale, and Social Skills Rating System (SSRS) were administered before and after the intervention. The experimental group exhibited significantly higher scores than the control group on all of the scales except subscales of the Self-Expression scale and the SSRS. The results of this study suggest that group music therapy can facilitate children's engagement in group work and that playing an important role in the group can positively impact their perceptions of themselves.

• The Journal of Korean Academic Society of Nursing Education
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• v.13 no.1
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• pp.114-122
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• 2007

Purpose: This study was aimed at evaluating the effects of Music Therapy for the autistic children. Method: The subjects of this study consisted of 3 autistic children who were trained in an Attachment Promotion Therapy Program for 6 months. The Children were all males and 4years 9months, 3years 1 month, and 3years 8month each, and diagnosed with Autism by Child and Adolescent Psychiatrists. Data was collected by using video-taping methods(ADOS, Fagot's Interactive Behavior Code), an interview and observational methods(SMS). Music Therapy intervention was done once a week for 6 months. Data was gathered by quantitative and qualitative analysis. Result: This study showed that the Autism Diagnostic Observation Scale and Social Maturity Quotient(SQ) much improved after the Music Therapy After the Music Therapy, the Interactive Behavior Code : Gaze, Gesture for the communication, Verbal language, Laughing/Smile, and Normal play behaviors increased more than before the intervention. As the results show, the child's behavior became more positively responsive, playful, and attentive to others. Conclusion: This study suggests that Music Therapy might be an effective intervention for autistic disorder children in order to decrease autistic symptoms and increase joint attention behavior.

• IMMUNE NETWORK
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• v.9 no.4
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• pp.115-121
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• 2009

Natural killer (NK) cells play key roles in innate and adaptive immune defenses. NK cell responses are mediated by two major mechanisms: the direct cytolysis of target cells, and immune regulation by production of various cytokines. Many previous reports show that the complex NK cell activation process requires de novo gene expression regulated at both transcriptional and post-transcriptional levels. Specialized un-translated regions (UTR) of mRNAs are the main mechanisms of post-transcriptional regulation. Analysis of posttranscriptional regulation is needed to clearly understand NK cell biology and, furthermore, harness the power of NK cells for therapeutic aims. This review summarizes the current understanding of mRNA metabolism during NK cell activation, focusing primarily on post-transcriptional regulation.