• Title/Summary/Keyword: Pioneering

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Making Trend-Based on Brand Marketing Strategy of Samsung Raemian (트렌드 창출을 통한 삼성물산 래미안의 브랜드 마케팅전략)

  • Jeon, Jung Ok;Cho, Bong Jin;Lee, Myung Sik
    • Asia Marketing Journal
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    • v.6 no.3
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    • pp.123-141
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    • 2004
  • As a pioneering company who entered new era of brand marketing in the domestic housing development market, Construction Division of Samsung Corporation achieved enormous business performance with the brand asset at the short time period. For the great success, they tried to apply customer's value into marketing mix strategy thoroughly, and created new trend of brand marketing strategy in the field. This case deals with the Samsung Corporation's efforts mainly focused on Raemian's brand marketing strategy to build the best powerful brand, and shows which are the key success factors, and suggest strategic implications to succeed in the long run.

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Regulation of CMGC kinases by hypoxia

  • KyeongJin Kim;Sang Bae Lee
    • BMB Reports
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    • v.56 no.11
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    • pp.584-593
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    • 2023
  • Hypoxia, a widespread occurrence observed in various malignant tumors, results from rapid tumor growth that outpaces the oxygen supply. Tumor hypoxia precipitates several effects on tumor biology; these include activating angiogenesis, intensifying invasiveness, enhancing the survival of tumor cells, suppressing anti-tumor immunity, and fostering resistance to therapy. Aligned with the findings that correlate CMGC kinases with the regulation of Hypoxia-Inducible Factor (HIF), a pivotal modulator, reports also indicate that hypoxia governs the activity of CMGC kinases, including DYRK1 kinases. Prolyl hydroxylation of DYRK1 kinases by PHD1 constitutes a novel mechanism of kinase maturation and activation. This modification "primes" DYRK1 kinases for subsequent tyrosine autophosphorylation, a vital step in their activation cascade. This mechanism adds a layer of intricacy to comprehending the regulation of CMGC kinases, and underscores the complex interplay between distinct post-translational modifications in harmonizing precise kinase activity. Overall, hypoxia assumes a substantial role in cancer progression, influencing diverse aspects of tumor biology that include angiogenesis, invasiveness, cell survival, and resistance to treatment. CMGC kinases are deeply entwined in its regulation. To fathom the molecular mechanisms underpinning hypoxia's impact on cancer cells, comprehending how hypoxia and prolyl hydroxylation govern the activity of CMGC kinases, including DYRK1 kinases, becomes imperative. This insight may pave the way for pioneering therapeutic approaches that target the hypoxic tumor microenvironment and its associated challenges.

A Study on Performance Analysis of Companies Adopting and Not Adopting Win-win Smart Factories (상생형 스마트공장 도입기업과 미도입기업의 성과분석에 관한 연구)

  • Jungha Hwang;Taesung Kim
    • Journal of the Korea Safety Management & Science
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    • v.26 no.1
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    • pp.45-53
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    • 2024
  • A Smart factories are systems that enable quick response to customer demands, reduce defect rates, and maximize productivity. They have evolved from manual labor-intensive processes to automation and now to cyber-physical systems with the help of information and communication technology. However, many small and medium-sized enterprises (SMEs) are still unable to implement even the initial stages of smart factories due to various environmental and economic constraints. Additionally, there is a lack of awareness and understanding of the concept of smart factories. To address this issue, the Cooperation-based Smart Factory Construction Support Project was launched. This project is a differentiated support project that provides customized programs based on the size and level of the company. Research has been conducted to analyze the impact of this project on participating and non-participating companies. The study aims to determine the effectiveness of the support policy and suggest efficient measures for improvement. Furthermore, the research aims to provide direction for future support projects to enhance the manufacturing competitiveness of SMEs. Ultimately, the goal is to improve the overall manufacturing industry and drive innovation.

Design and Implementation of a Career Guidance Program at Gachon University College of Medicine (가천대학교 의과대학 졸업 후 진로지도 프로그램 설계와 운영)

  • Kwi Hwa Park
    • Korean Medical Education Review
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    • v.26 no.1
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    • pp.41-47
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    • 2024
  • The ultimate goal of career guidance is to help medical students develop a career plan that matches their personal characteristics, allows them to train in their desired subspecialty, and helps them to adapt well to medical practice after graduation. Gachon Medical School has designed a longitudinal career guidance program called GLORI (Gachon Longitudinal Orientation and Career Development), which is based on the outcome of each phase. The program consists of regular courses and portfolio-based career guidance from a mentor professor. In phase 2 (basic medical science), the "Career Seminar" course was developed. This course focuses on self-understanding through a psychological inventory, exploration of postgraduate career paths, and interviews with professors in specialties of interest. In phase 3 (the integration of basic and clinical science), the "Exploring Nonclinical Career Options" course was introduced. This course presents perspectives from doctors who have followed various pioneering career trajectories, including biomedical engineering, medical journalism, writing, public health, health care administration, the pharmaceutical and medical device industries, and other areas. All teaching methods were designed to encourage student participation. The assessment methods are assignment-based, including self-reflective reports and presentations. In addition, a portfolio-based career guidance program is implemented in phases 3 and 4 (clinical clerkship). It is expected that this case study will serve as a practical example for developing comprehensive career guidance programs for medical schools.

RENE LAENNEC'S SYNDROME-BASED CLINICAL REASONING

  • Berezutskyi Volodymyr
    • CELLMED
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    • v.14 no.2
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    • pp.4.1-4.4
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    • 2024
  • The development of clinical reasoning, which is the basis of medical education, is of great importance in medical universities. One of the founders of modern structural clinical reasoning, based on the knowledge of pathological physiology, is the inventor of the stethoscope Rene Laennec (1781-1826). He described the pioneering experience of clinical reasoning in the pages of his treatise A Treatise on the Diseases of the Chest and on Mediate Auscultation, which is of lasting value, since every rookie physicians in his professional development goes through the path of Laennec. Laennec's practice is of great importance for novice physicians since Laennec's treatise contains a diagnostic analysis of the most common clinical cases. Each such analysis demonstrates the algorithm of clinical reasoning. The purpose of this study was to analyze the approaches of clinical reasoning by René Laennec, which made it possible to identify two basic principles. Laennec's diagnostic reasoning involved two principles: pathogenetic analysis of clinical manifestations and a syndrome-based approach to differential diagnosis. These principles help distinguish between diseases with similar symptoms and physical findings are used to demonstrate the practical application of syndrome-based differential diagnosis. These principles can be easily mastered by understanding the pathogenesis of clinical manifestations. Thanks to the pathogenetic basis, the principles of clinical reasoning of Rene Laennec are universal and applicable to the analysis of any signs of the disease: not only physical but also laboratory and instrumental.

Enhancing Data Protection in Digital Communication: A Novel Method of Combining Steganography and Encryption

  • Khaled H. Abuhmaidan;Marwan A. Al-Share;Abdallah M. Abualkishik;Ahmad Kayed
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.18 no.6
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    • pp.1619-1637
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    • 2024
  • In today's highly digitized landscape, securing digital communication is paramount due to threats like hacking, unauthorized data access, and network policy violations. The response to these challenges has been the development of cryptography applications, though many existing techniques face issues of complexity, efficiency, and limitations. Notably, sophisticated intruders can easily discern encrypted data during transmission, casting doubt on overall security. In contrast to encryption, steganography offers the unique advantage of concealing data without easy detection, although it, too, grapples with challenges. The primary hurdles in image steganography revolve around the quality and payload capacity of the cover image, which are persistently compromised. This article introduces a pioneering approach that integrates image steganography and encryption, presenting the BitPatternStego method. This novel technique addresses prevalent issues in image steganography, such as stego-image quality and payload, by concealing secret data within image pixels with identical bit patterns as their characters. Consequently, concerns regarding the quality and payload capacity of steganographic images become obsolete. Moreover, the BitPatternStego method boasts the capability to generate millions of keys for the same secret message, offering a robust and versatile solution to the evolving landscape of digital security challenges.

A Study of Costumes in the $Lo{\ddot{i}}e$ Fuller's Dance (로이 풀러의 무대 의상에 관한 연구)

  • Choi, Yoo-Jin
    • The Research Journal of the Costume Culture
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    • v.16 no.5
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    • pp.878-890
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    • 2008
  • As a pioneer of modem dance, $Lo{\ddot{i}}e$ Fuller($1869\sim1928$) was important because she introduced a free style dance using a new style of stage costumes. Also, $Lo{\ddot{i}}e$ Fuller was an important motif in $fin-de-si{\grave{e}}cle$, French arts, posters, sculptures, and so forth. This study aimed to clarify the characteristics of Fuller's dance and costumes, and to analyze the modernism in both. To better understand Fuller's dance, this article talks about research on Fuller's career, dance, and Fuller's own biography. Stage costumes, letters for patent, and photographs were are also studied. The most important elements of Fuller's dance were her costumes and the electric lights which could make free style expressions a fantastic representation of dance. To clarify the modernity of Fuller's dance, first of all, this study researched Fuller's career in dance and then analyzed representations of Fuller's dances in visual arts; posters, sculptures and lastly, the characteristics of Fuller's stage costumes. As a result, this article analyzed characteristics of Fuller's dance in three points. First, Fuller used sculptures of silk cloth's drapery to express physical movements and actions. Second, Fuller used lighting and electrical effects that had just been developed in the late 19th Century. Third, Fuller made an application for patents against stage costume and stage mechanisms for her original shows. This study focused on $Lo{\ddot{i}}e$ Fuller's stage costumes which played a main role in expressing fantastic sculptures for the first time in costume, visual arts, and dance studies. This study clarifies the characteristics of the stage costumes in Fuller's dance and is estimated as pioneering and fundamental research.

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A Study on Goddesses Hair Arts Shown in History of Arts (미술사에 표현된 여신의 헤어 아트 연구)

  • Lee, Hyun-Jin;Kim, Sun-Ah
    • Fashion & Textile Research Journal
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    • v.9 no.6
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    • pp.663-670
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    • 2007
  • Arts is the expression of reasoning and conscious life of human and arouse human the concept of existence, utmost emotion and excellent thoughts. Also it makes humans life very abundant. I make it come first to get rid of the art thirst on the opposite sight of technical one for hair as on part of humans body. Next purpose is that to confirm the esthetic value of 'hair arts' by solidify the academic ground of beauty arts through creating 'hair arts' works and learning and make the direction for the beauty industry and education of the next generation. In this study I investigated the Greek myth and the hair styles of ancient Greek Goddesses. On the basis of that symbols I elaborated hair formative works made of metal and studied, analyzed and displayed that. Work No.1 'aphne' pictures the second of changing into a laurel tree avoiding the love. Secondly 'Muse Erato' was exhibited the peaceful figure that have enough the fine melodies. 'Leda' brings out the feature of Leda resembling a swan and the fourth piece, 'Eos' conveys the brilliant and mystery of dawn. So this study conducted based on the concept of practical hair and have made efforts to be close to theoretical manufacturing research needed at making hair arts works and academic one needed at organic design composition for pioneering new field, 'art hair.' I hope these 'hair arts' works make creativity of the practise hair alive. It will be very thankful to me if this study can help even though slightly for splendid beauty arts to make its status firm as a one part of arts, and there are following studies.

Searching Role of Government for Promoting IoT Industry -Utilizing Importance of Individual Sub-Policies using AHP- (사물인터넷(IoT) 산업 진흥을 위한 정부의 역할에 관한 연구 -AHP를 활용한 정책 중요도 분석을 중심으로-)

  • Lee, Yong-Kyu;Youn, Ku-Hong
    • Journal of Digital Convergence
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    • v.14 no.5
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    • pp.47-55
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    • 2016
  • The purpose of this study is to analyze the status of various government support policy for IoT sector and survey the level of satisfaction and relative importance among policies. In order to achieve the goal, this study surveyed experts in the field of IoT, utilizing Hierarchy Process Analysis methods. Major findings are as follows; first, despite of wide range of IoT-related policies, experts in the industry and academy are very limited, ; second, the order of policy satisfaction is primarily on Oversea Marketing, followed by R&D support, Venture support, Human resource education.; third, the order of importance is primarily Venture support, followed by R&D support, Human resource education. Also, it has been given the higher importance to the role of leader as R&D support, Oversea market pioneering, and industry university network, rather than the role of coordinator and supporter. However, expert group does not recognize the importance of policies related to the role of coordinator because these policies always have been conducted in major government projects.

Assessment Model of Core Manufacturability to Promote Collaboration of Small and Medium Sized Mold Companies (중소 금형업체 협업지원을 위한 핵심 제조역량 평가 모델 개발)

  • Shin, Moon-Soo;Lee, San-Gil;Ryu, Kwang-Yeo;Joo, Jae-Koo
    • IE interfaces
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    • v.25 no.1
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    • pp.52-63
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    • 2012
  • Up-to-date enlargement of the scale of global outsourcing has brought about the need of systematic and efficient tools for competitive supplier discovery located in various areas. A web-based business supporting system, referred to as Excellent Manufacturer Scouting System(EMSS), is being developed to serve core business functions including supplier discovery, negotiation, and collaboration between overseas buyers and domestic suppliers throughout the process of supply chain formation. In this paper, a supplier assessment model devoted to evaluation of core manufacturing capability is proposed by targeting small and medium sized mold companies. The assessment model will eventually be loaded to EMSS. Even if many well-designed models for supplier assessment have been presented in literature, most of them limit the evaluation criteria to somewhat general information on a given supplier, such as cost, delivery time, quality, rather than core manufacturing capability itself. This research is pioneering work on supplier assessment from the viewpoint of manufacturability. The proposed assessment model classifies assessment indices into six criteria, which have been drawn by intensive survey and analysis of the mold industry. Actual assessment indices for each criterion are also presented along with an exemplary evaluation result.