• 한국노년학
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• v.30 no.1
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• pp.65-80
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• 2010

Purpose: The purpose of this study was to develop a wisdom scale among Korean elderly with high validity and reliability. Method: The process of the development of this scale follows: A conceptual framework was identified based on literature a review of the elderly and discussion with experts in physiology and sociology. Total 128 items were developed. Through reliability testing, factor analysis, 60 preliminary items, and 4-points scale were selected. By a means of the internal consistency for 60 items, 33 items were deleted. Finally, 27 items were remained. To verity 27 items, factor analysis, reliability testing, and correlation were done. Data were collected from 480 elderly subjects in Daegu, Kyungpook Province, and Busan, Kyungnam Province from August, 2008 to February, 2009. Results: From the results of the factor analysis for 27 items, 3 factors were extracted. These factors were labeled as 'empathic emotion', 'self-reflection', and 'bitter experience of life'. Cronbach's Alpha for the 27 items was .921 and correlation coefficient of ego-integrity was .69. Conclusion: An exploratory study of the variables related to wisdom among the elderly is needed for criterion validity of this scale. A study on wisdom for different age groups is needed for re-verification.

• Korean Journal of Health Education and Promotion
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• v.12 no.2
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• pp.73-89
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• 1995

This study was planned to investigate indirectly the effects of study environments of high school students such as family characteristics, availability of sex education, and possibility of exposure to unhealthy sexual environments. For this purpose, the level of knowledge and attitude towards sex of general and industrial high school students were compared because these two groups of students were believed to be different in those study variables. For this study, 600 students (300 male and 300 female students) from a general high school students and 400 (200 male and 200 female) from an industrial high school in one industrial city in Korea were surveyed with a structured questionnaire. The study results were as follows: 1. There were significant differences in selected family condition variables between general and industrial high school students. Proportions of students with single parents, those who live in houses other than their own, and those father's occupations were farming and manufacturing were higher in industrial high school students than in general high school students. 2. Female students wanted to have more knowledge on sex whereas male students were interested in things related to sexual acts in both general and industrial high school students. The largest proportion of students wanted to discuss their sex problems with their friends not with their parents. 3. More students in general high school thought that the sexual intercourse is natural and pretty than those in industrial high school, whereas more industrial high school students insisted on the sexual purity before marriage than general high school students. 4. About 65% of students surveyed agreed to making friends with opposite sex and, in fact, more than half either had experiences or were having friends of opposite sex. More students in industrial high school wanted to choose their marital partners based on advices of their parents than students in general high school. 5. More female students than male and more industrial high school students than general high school students were embarrassed with first wet dream or menstruation and felt guilty about the masturbation. 6. Level of knowledge on reproductive physiology, sex transmitted disease and contraception was higher in general high school students than in industrial high school students. These study results suggest that simple knowledge on sex of the general high school students does not seem to affect positively the students attitude towards sex and the unfavorable living conditions of industrial high school students seem to influence the students to become more sincere and healthy in their attitude towards sex and life. Therefore, more thoughtful consideration in contents and methods should be given when the sex education is provided to the high school students.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.5
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• pp.384-390
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• 2020

Purpose: Organophosphate insecticide poisoning can have clinically fatal results. This study aimed to evaluate the relationship between the neutrophil/lymphocyte ratio (NLR) and the occurrence of death in patients with organophosphate insecticide poisoning. Methods: For this retrospective study, data on patients with organophosphate insecticide poisoning who visited the emergency room between January 2008 and November 2018 were collected. The NLR was measured at the time of arrival in the emergency room. The patients were divided into survival and death groups. Results: Overall, 150 patients were enrolled: 15 (10%) in the death group and 135 (90%) in the survival group. In the univariate analysis, the following variables were significantly different between the two groups: age, white blood cell count, amylase level, creatinine level, Acute Physiology And Chronic Health Evaluation (APACHE) II score, and NLR. In the logistic regression analysis of variables with significant differences in the univariate analysis, there were significant differences between the two groups with respect to age, APACHE II score, and NLR. The NLR was significantly higher in the death group than in the survival group (20.83 ± 22.24 vs. 7.38 ± 6.06, p=0.036). Conclusion: High NLR in patients with organophosphate insecticide poisoning may be useful in predicting mortality.

• Tuberculosis and Respiratory Diseases
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• v.68 no.5
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• pp.259-266
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• 2010

Background: Pulmonary tuberculosis (TB), requiring the intensive care unit (ICU) care, has been a high-mortality condition until now. In the present study, we aimed to investigate clinical features and parameters associated with TB mortality. Methods: From August 2003 to December 2008, patients with microbiologically or histologically confirmed pulmonary TB then admitted to the ICU, were retrospectively enrolled into the study. Upon enrollment, their medical records were reviewed. Results: Forty three patients (30 males, 13 females) were included and their mean age was 63.8 years (range: 17~87 years). Twelve patients died, an overall in-hospital mortality of 27.8%. The main reason for the ICU care was dyspnea or hypoxemia requiring mechanical ventilation (n=17). Other diagnoses for ICU care were hemoptysis, monitoring after procedures, neurologic dysfunction, shock, and gastrointestinal bleeding. On univariate analysis, the factors affecting the mortality were malnutrition-related parameters including low body mass index, hypoalbuminemia, lymphocytopenia, and hypocholersterolemia, as well as severity-related variables such as high acute physiology and chronic health evaluation (APACHE) score, number of involved lobes, and high C-reactive protein. In addition, respiratory failure requiring mechanical ventilation and acute respiratory distress syndrome contributed to patient fatality. It was shown on multivariate analysis that respiratory failure and hypoalbuminemia were significantly independent variables associated with the mortality. Conclusion: Acute respiratory failure is the most common reason for the ICU care and also the most important factor in predicting poor outcome. In addition, our data suggest that the parameters associated with malnutrition could be possible factors contributing to mortality.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.6
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• pp.970-975
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• 2012

In Sasang constitutional medicine, doctors diagnose and treat patients according to their Sasang consitutition (SC) type. In this work, by a clinical test with a radial pulse tonometer, we investigated radial pulse properties which were significant in distinguishing unhealthy subjects from healthy subjects for each SC type. We measured radial pulse properties on left and right Gwan locations with a pulse tonometer for 299 elderly female subjects of age of 50 years old or above. We used a newly developed SCAT system to determine subjects' SC types. Subjects' health levels of either healthy or unhealthy were determined independently by two Korean medical doctors. To investigate the statistical differences, we used either of Student's t-test or Mann-Whitney U test depending on the normality of distribution of test statistic. For TE type, unhealthy subjects were characterized with significant increases in heart rate, systolic to diastolic period, pulse depth, while they showed significant decreases in width of pulse in normal direction, pulse area in diastolic period, and high harmonic components (6th, 7th) of power spectral density. For SE type, unhealthy subjects were characterized with significant increases in pulse pressure and pulse depth, while no significant differences were found for SY type. We investigated the characteristic differences in radial pulse properties due to change in health levels on each SC type for elderly females. Pulse variables which were significantly different between healthy subjects and unhealthy subjects were found to vary between SC types. For TE type subjects, many variables were found significant at the left Gwan location, which is in support of the theory of hyperactive liver functioning for TE type. Irrespective of the constitution, the related changes in the pulse properties due to worsened health level were in support of elevated blood flow amount in compensation with weakened blood circulatory function.

• Journal of Life Science
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• v.21 no.9
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• pp.1336-1345
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• 2011

The purpose of this study was to analyze and compare the effects of exercise science of shoes for Aged' health promotion. Kinematic and kinetic data were collected using cinematography and the Zebris system (Zebris Emed Sensor Platform, GR-DVL9800) to analyze pressure of foot and ground reaction force. Subjects recruited were 20 healthy elderly men. They walked at 1.36m/sec velocity wearing type A (domestic), type B (foreign) and walking shoes (A company). One-way ANOVA was used to analyze statistics. The results were as following: no significant differences were observed in gait variables among the three groups (p<0.05). There was a significant difference in max pronation angle of heels examined among the three groups (p<0.05). There were no significant differences in kinetic variables (ground reaction force and max pressure) among the three groups (p<0.05). A physiology study was performed to analyze the effects of walking with shoes with silver added to them on percent body fat, resting metabolic rate and energy expenditure. Sixty adults males were recruited from the public health center. They were divided into four groups. C: control group (n=20), EY: elderly Y group (n=20), and EO: elderly O group (n=20). The results of this study were as follows: percent body fat was decreased following each exercise period, however, not all the groups showed a significant difference. The change of resting metabolic rate was significantly increased in HI (high intensity) and LI (low intensity) periods in the C and EY groups. However, there was no significant difference in the EO group. The mean energy expenditure during and after exercise were significantly lowered in all periods compared to the control group.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.50 no.6
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• pp.369-377
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• 2005

Precise application of topdressing nitrogen (N) fertilizer is indispensible for securing high yield and good quality of rice and minimizing N losses to the environment as well. For precise N management, growth and nitrogen nutrition status (NNS) should be diagnosed rapidly and accurately. The objective of the study was to evaluate the applicability of vegetation index (VI) calculated from hyperspectral canopy reflectance measurement and SPAD reading to nondestructive in situ diagnosis of growth and NNS of rice. Canopy reflectance, SPAD read­ing, growth parameters, and NNS characteristics were measured from various N treatments to evaluate the relationships among them for two cropping seasons from 2001 to 2002. The correlation coefficient of VIs with variables of growth and NNS increased positively as rice canopy became more closed. Regardless of growth stages, VIs had significantly high correlations with LAI, shoot dry weight (DW), shoot N content and nitrogen nutrition index (NNI). Those correlation coefficients increased steadily before heading stage as rice grew up. However, tiller number and leaf N concentration showed significantly high correlations with VIs only at and after panicle initiation stage (PIS). Among the VIs, RVIgreen had significantly higher correlation with the measured parameters than the other VIs: it showed correlation coefficients greater than 0.8 with leaf and shoot N concentration and DW, and much higher coefficients greater than 0.9 with LAI, shoot N content, and NNI. At LAI of below 2.5, VIs had non-significant or low correlations with the growth and NNS indicators due to the background effects. SPAD reading had significantly high correlation with leaf N concentration and NNI at each growth stage. In addition, it had significant correlations with variables of growth and NNS at PIS and booting stage, particularly, at booting stage. Though SPAD reading had a significantly high correlation value at a given growth stage in each year, it showed very weak relationship with variables of growth and NNS when pooled across growth stages and years. In conclusion, RVIgreen was found to be the most reliable VI to estimate the growth and NNS of rice around at PIS, but SPAD reading had much limitations.

• Journal of Physiology & Pathology in Korean Medicine
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• v.31 no.2
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• pp.118-125
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• 2017

The purpose of this study is to investigate the blood pressure reducing effect of Qi-Ju-Di-Huang-Wan (QJDHW) in adults with essential hypertension by using methods of systemic review and meta-analysis. Major search engines, such as PubMed, EMBASE, Cochrane library, Web of Science, CNKI, CiNii, J-STAGE, KISS, NDSL, RISS, OASIS, DBpia and so on, were used. The search period we used is from the start date of the search engine to October 30, 2016 and no language limits were placed. Randomized controlled trials using QJDHW in adults with essential hypertension were searched and extracted by two independent researchers. Meta-analysis was performed on outcome variables of the total effective rate (TER), systolic blood pressure (SBP) and diastolic blood pressure (DBP). Risk of bias (RoB) of Cochrane was used to assess methodological quality. Thirteen studies were finally selected. We observed that the combined treatment of QJDHW and antihypertensive drug had 3.6 times the odds ratio of TER for blood pressure lowering than a single use of an antihypertensive drug. Additionally, mean differences of SBP and DBP were -8.88 mmHg (95% Confidential Interval (CI) -12.77 mmHg, -5.00 mmHg, P<0.00001), -7.09 mmHg (95% CI -9.93, -4.25, P <0.00001), respectively. Single use of QJDHW did not reduce blood pressure more than an antihypertensive drug. All items of RoB were unclear and the methodological quality was low. Our analysis suggests that the combination of QJDHW and antihypertensive drugs may be more effective in reducing blood pressure than a single antihypertensive drug. But due to low methodological quality, careful interpretation will be needed and systematic long-term clinical trials will be required.

• Genomics & Informatics
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• v.10 no.2
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• pp.88-98
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• 2012

Lipoprotein lipase (LPL) plays an essential role in the regulation of high-density lipoprotein cholesterol (HDLC) and triglyceride levels, which have been closely associated with cardiovascular diseases. Genetic studies in European have shown that LPL single-nucleotide polymorphisms (SNPs) are strongly associated with lipid levels. However, studies about the influence of interactions between LPL SNPs and lifestyle factors have not been sufficiently performed. Here, we examine if LPL polymorphisms, as well as their interaction with lifestyle factors, influence lipid concentrations in a Korean population. A two-stage association study was performed using genotype data for SNPs on the LPL gene, including the 3' flanking region from 7,536 (stage 1) and 3,703 (stage 2) individuals. The association study showed that 15 SNPs and 4 haplotypes were strongly associated with HDLC (lowest $p=2.86{\times}10^{-22}$) and triglyceride levels (lowest $p=3.0{\times}10^{-15}$). Interactions between LPL polymorphisms and lifestyle factors (lowest $p=9.6{\times}10^{-4}$) were also observed on lipid concentrations. These findings suggest that there are interaction effects of LPL polymorphisms with lifestyle variables, including energy intake, fat intake, smoking, and alcohol consumption, as well as effects of LPL polymorphisms themselves, on lipid concentrations in a Korean population.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.5
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• pp.1087-1094
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• 2009

The purpose of this study was investigated hypoglycemic effects of fermented red ginseng extracts. We prepared non-fermented red ginseng extracts(R), fermented with Lactobacillus plantarum(RL) extracts, Saccharomycescerevisiae(RS) extracts, and L. plantarum mixed S. cerevisiae(RLS) extracts, examined composition of ginsenosides, SOD-like activity, and $\alpha$-glucosidase inhibitory activity. Ginsenoside Re was highest contents in all extracts, second was ginsenoside Rc and then ginsenoside Rb1. Concentration of these ginsenoside was showed higher in RS than in other extracts. SOD-like activity and $\alpha$-glucosidase inhibitory activity were shown higher in fermented red ginseng extracts than non fermented extracts. And activities of mixed fermentation extracts(RLS) higher than single fermentation extracts(RL, RS). Effects of blood glucose level, serum lipid profile and metabolic variables were evaluated in streptozotocin(STZ) induced diabetic rat. Experimental group was divided into 7 groups: normal control group(hereafter NC group), diabetes control group(DC group), positive control group treated with 50 mg/kg body weight of acarbose(PC group), treated with 300 mg/kg body weight of R, RL, RS and RLS extracts groups, respectively. Blood glucose level of DC group was maintained high level in all experimental period, but treated with red ginseng extracts groups was reduced the glucose level by R group 18.00%, RL group 28.07%, RS group 29.03%, RLS group 42.42%, respectively. The concentration of total cholesterol and triglyceride of fermented red ginseng extracts treated groups (RL, RS, RLS) was lower than non- fermented extracts group(R) DC and PC groups. The activity of ALT, AST in RLS treated groups were lower than other groups.