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http://dx.doi.org/10.5762/KAIS.2020.21.5.384

Role of neutrophil/lymphocyte ratio as a predictor of mortality in organophosphate poisoning  

Jeong, Jae Han (Department of Thoracic and Cardiovascular surgery, Chosun University)
Sun, Kyung Hoon (Department of Emergency Medicine, Chosun University)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.21, no.5, 2020 , pp. 384-390 More about this Journal
Abstract
Purpose: Organophosphate insecticide poisoning can have clinically fatal results. This study aimed to evaluate the relationship between the neutrophil/lymphocyte ratio (NLR) and the occurrence of death in patients with organophosphate insecticide poisoning. Methods: For this retrospective study, data on patients with organophosphate insecticide poisoning who visited the emergency room between January 2008 and November 2018 were collected. The NLR was measured at the time of arrival in the emergency room. The patients were divided into survival and death groups. Results: Overall, 150 patients were enrolled: 15 (10%) in the death group and 135 (90%) in the survival group. In the univariate analysis, the following variables were significantly different between the two groups: age, white blood cell count, amylase level, creatinine level, Acute Physiology And Chronic Health Evaluation (APACHE) II score, and NLR. In the logistic regression analysis of variables with significant differences in the univariate analysis, there were significant differences between the two groups with respect to age, APACHE II score, and NLR. The NLR was significantly higher in the death group than in the survival group (20.83 ± 22.24 vs. 7.38 ± 6.06, p=0.036). Conclusion: High NLR in patients with organophosphate insecticide poisoning may be useful in predicting mortality.
Keywords
Organophosphate poisoning; Neutrophil; Lymphocyte; APACHE; Mortality;
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