• Current Optics and Photonics
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• v.5 no.6
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• pp.711-720
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• 2021

A novel optical hybrid device that doubles the multilevel demodulation resolution by adding the optical interferometer with a waveguide crossover is proposed, theoretically analyzed and experimentally verified. We report two types of all-passive phase control schemes that will be referred to as a phase compensation scheme and a phase optimization scheme. We also apply the proposed phase control schemes to a 45° optical hybrid consisting of two parallel 90° optical hybrids together with the proposed phase control scheme for demodulating 8-level differential phase shift keying optical signals. Octagonal phase response with low wavelength sensitive excess loss of <0.8 dB over 31-nm-wide spectral range will be demonstrated in the InP-based material platform.

• Journal of Biomedical Engineering Research
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• v.25 no.4
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• pp.269-275
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• 2004

Different biological tissues have different values of electrical resistivity. In EIT (electrical impedance tomography), we try to provide cross-sectional images of a resistivity distribution inside an electrically conducting subject such as the human body mainly for functional imaging. However, it is well known that the image reconstruction problem in EIT is ill-posed and the quality of a reconstructed image highly depends on the measurement error. This requires us to develop a high-performance EIT system. In this paper, we describe the development of a 16-channel digital EIT system including a single constant current source, 16 voltmeters, main controller, and PC. The system was designed and implemented using the FPGA-based digital technology. The current source injects 50KHz sinusoidal current with the THD (total harmonic distortion) of 0.0029% and amplitude stability of 0.022%. The single current source and switching circuit reduce the measurement error associated with imperfect matching of multiple current sources at the expense of a reduced data acquisition time. The digital voltmeter measuring the induced boundary voltage consists of a differential amplifier, ADC, and FPGA (field programmable gate array). The digital phase-sensitive demodulation technique was implemented in the voltmeter to maximize the SNR (signal-to-noise ratio). Experimental results of 16-channel digital voltmeters showed the SNR of 90dB. We used the developed EIT system to reconstruct resistivity images of a saline phantom containing banana objects. Based on the results, we suggest future improvements for a 64-channel muff-frequency EIT system for three-dimensional dynamic imaging of bio-impedance distributions inside the human body.

• Journal of the Korean Society for Nondestructive Testing
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• v.26 no.6
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• pp.380-389
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• 2006

A new laser-based ultrasonic receiver that is based on multi-channel interferometry is shown to be well suited for robust and sensitive detection of ultrasound in industrial environment. The proposed architecture combines random-quadrature detection with detector arrays and parallel multi-speckle processing. The high sensitivity is reached, thanks to the random phase distribution of laser speckle caused by surface roughness. High-density parallel signal processing is achieved by using a simple demodulation technique based on signal rectification. This simple detection scheme is also demonstrated for rejection of the laser intensity noise, making possible the use of lower cost laser without reduction in performances. Results demonstrating this new principle of operation and its performances are presented.

• Journal of Biomedical Engineering Research
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• v.28 no.1
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• pp.66-74
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• 2007

We have developed a multi-channel, multi-frequency EIT system with operating frequency of 10Hz to 500KHz. The number of digital voltmeters using phase-sensitive demodulation can be varied from 8 to 64 and we found that 16 and 32-channels are most practical. This paper describes the design, implementation, and construction of 16 and 32-channel systems. The performance of the system was thoroughly tested and we found that CMRR of the developed voltmeter is about 85dB with $100{\Omega}$ unbalancing series resistor. The SNR is greater than 99.6dB and the output impedance of the constant current source is $1{\Omega}W$ at least for all frequencies. Imaging experiments using a banana with frequency-dependent conductivity and permittivity show that frequency-difference imaging is possible using the developed system. Future works of animal and human experiments are discussed.

• Journal of Biomedical Engineering Research
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• v.26 no.4
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• pp.215-221
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• 2005

We describe the development of a prototype multi-channel electrical impedance tomography (EIT) system. The EIT system can be equipped with either a single-ended current source or a balanced current source. Each current source can inject current between any chosen pair of electrodes. In order to reduce the data acquisition time, we implemented multiple digital voltmeters simultaneously acquiring and demodulating voltage signals. Each voltmeter measures a differential voltage between a fixed pair of adjacent electrodes. All voltmeters are configured in a radially symmetric architecture to optimize the routing of wires and minimize cross-talks. To maximize the signal-to-noise ratio, we implemented techniques such as digital waveform generation, Howland current pump circuit with a generalized impedance converter, digital phase-sensitive demodulation, tri-axial cables with both grounded and driven shields, and others. The performance of the EIT system was evaluated in terms of common-mode rejection ratio, signal-to-noise ratio, and reciprocity error. Future design of a more innovative EIT system including battery operation, miniaturization, and wireless techniques is suggested.

• Journal of Biomedical Engineering Research
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• v.28 no.1
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• pp.84-94
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• 2007

In order to collect information on local distribution of conductivity and permittivity underneath a scan probe, we developed a multi-frequency trans-admittance scanner (TAS). Applying a sinusoidal voltage with variable frequency on a chosen distal part of a human body, we measure exit currents from 320 grounded electrodes placed on a chosen surface of the subject. The electrodes are packaged inside a small and light scan probe. The system includes one voltage source and 17 digital ammeters. Front-end of each ammeter is a current-to-voltage converter with virtual grounding of a chosen electrode. The rest of the ammeter is a voltmeter performing digital phase-sensitive demodulation. Using resistor loads, we calibrate the system including the scan probe to compensate frequency-dependent variability of current measurements and also inter-channel variability among multiple. We found that SNR of each ammeter is about 85dB and the minimal measurable current is 5nA. Using saline phantoms with objects made from TX-151, we verified the performance of the lesion estimation algorithm. The error rate of the depth estimation was about 19.7%. For the size estimate, the error rate was about 15.3%. The results suggest improvement in lesion estimation algorithm based on multi-frequency trans-admittance data.

• Journal of Biomedical Engineering Research
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• v.25 no.5
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• pp.335-342
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• 2004

This paper describes a trans-admittance scanner for breast cancer detection. A FPGA-based sinusoidal waveform generator produces a constant voltage. The voltage is applied between a hand-held electrode and a scan probe placed on the breast. The scan probe contains an 8x8 array of electrodes that are kept at the ground potential. Multi-channel precision digital ammeters using the phase-sensitive demodulation technique were developed to measure the exit current from each electrode in the array. Different regions of the breast are scanned by moving the probe on the breast. We could get trans-admittance images of resistor and saline phantoms with an anomaly inside. The images provided the information on the depth and location of the anomaly. In future studies, we need to improve the accuracy through a better calibration method. We plan to test the scanner's ability to detect a cancer lesion inside the human breast.