• Clinical and Experimental Pediatrics
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• v.54 no.11
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• pp.473-476
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• 2011

Primary hypokalemic periodic paralysis (HOKPP) is an autosomal dominant disorder manifesting as recurrent periodic flaccid paralysis and concomitant hypokalemia. HOKPP is divided into type 1 and type 2 based on the causative gene. Although 2 different ion channels have been identified as the molecular genetic cause of HOKPP, the clinical manifestations between the 2 groups are similar. We report the cases of 2 patients with HOKPP who both presented with typical clinical manifestations, but with mutations in 2 different genes ($CACNA1S$ p.Arg528His and $SCN4A$ p.Arg672His). Despite the similar clinical manifestations, there were differences in the response to acetazolamide treatment between certain genotypes of $SCN4A$ mutations and $CACNA1S$ mutations. We identified p.Arg672His in the $SCN4A$ gene of patient 2 immediately after the first attack through a molecular genetic testing strategy. Molecular genetic diagnosis is important for genetic counseling and selecting preventive treatment.

• Korea-Australia Rheology Journal
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• v.18 no.4
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• pp.171-181
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• 2006

We present a short review for authors' previous work on direct numerical simulations for inertialess hard particle suspensions formulated either with a Newtonian fluid or with viscoelastic polymeric fluids to understand the microstructural evolution and the bulk material behavior. We employ two well-defined bi-periodic domain concepts such that a single cell problem with a small number of particles may represent a large number of repeated structures: one is the sliding bi-periodic frame for simple shear flow and the other is the extensional bi-periodic frame for planar elongational flow. For implicit treatment of hydrodynamic interaction between particle and fluid, we use the finite-element/fictitious-domain method similar to the distributed Lagrangian multiplier (DLM) method together with the rigid ring description. The bi-periodic boundary conditions can be effectively incorportated as constraint equations and implemented by Lagrangian multipliers. The bulk stress can be evaluated by simple boundary integrals of stresslets on the particle boundary in such formulations. Some 2-D example results are presented to show effects of the solid fraction and the particle configuration on the shear and elongational viscosity along with the micro-structural evolution for both particles and fluid. Effects of the fluid elasticity has been also presented.

• Journal of Korean Medicine Rehabilitation
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• v.30 no.1
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• pp.115-123
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• 2020

Objectives The aim of this study was to investigate the effects of liver-tonification acupuncture (LTA) on periodic muscle cramps (MC). Methods We retrospectively reviewed medical records of 28 patients treated for periodic MC with LTA in a Korean medicine clinic. Patients were treated with (A) LTA alone, (B) LTA and treatments for myofascial meridian, or (C) LTA and treatments for other diseases. We mainly investigated effectiveness of treatments, the number of treatments, the number of relapses, and time to relapse. Results After treatments, periodic MC disappeared in all patients except two in group C. The number of treatments in group C was significantly greater than that of group A (p<0.05). Periodic MC recurred in one patient in each of groups A and C, but symptoms disappeared after re-treatments. Periodic MC did not recur for a median of 7.0, 8.5, and 5.0 weeks in groups A, B, and C, respectively. Conclusions We found some therapeutic effects of LTA treatments for periodic MC in middle-aged and elderly patients.

• Journal of Periodontal and Implant Science
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• v.33 no.2
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• pp.215-223
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• 2003

The main goal of periodontal treatment is the long-term maintenance of teeth. Periodic maintenance program is need to prevent periodontal disease and maintain healthy periodontium. Hirschfeld and Wasserman(1978) studied 600 treated periodontal patients. This study categorized periodontal patients using well-maintained, downhill, extreme downhill groups. The purpose of our study is to evaluate effect of periodontal treatment and analyse tooth loss after periodontal treatment using this classification. The study population of j9 patients had been treated and maintained for mean 5.8 years. All patients were on a periodic maintenance program at 2-, 3-, 4, or 6-month intends. The avenge age of the patients at the time of original therapy was 49.6 years. To analyse tooth loss, modified classification was used on the basis of response to therapy using by Hirschfeld and Wasserman in 1978. The results were as follows : 1. 59 treated patients were lost mean 1.42 teeth per patient for 5.8 years of maintenance period. 2. Maxillary first molars were most frequently lost but mandibular lateral incisors were lost no tooth during maintenance period. 3. Tooth mortality received surgical treatment had similar to received nonsurgical treatment. 4. Tooth loss was more frequent in maxillary teeth than mandibular teeth, and posterior teeth than anterior teeth, and more frequent tendency in male than female.

• Proceedings of the Membrane Society of Korea Conference
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• 1999.04a
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• pp.131-134
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• 1999

• The Plant Pathology Journal
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• v.29 no.3
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• pp.294-304
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• 2013

To improve the integrated pest management (IPM) of hot pepper, field study was conducted in Hwasung from 2010 to 2012 and an IPM system was developed to help growers decide when to apply pesticides to control anthracnose, tobacco budworm, Phytophthora blight, bacterial wilt, and bacterial leaf spot. The three field treatments consisted of IPM sprays following the forecast model advisory, a periodic spray at 7-to-10-day intervals, and no spray (control). The number of annual pesticide applications for the IPM treatment ranged from six to eight, whereas the plots subjected to the periodic treatment received pesticide 11 or 12 times annually for three years. Compared to the former strategy, our improved IPM strategy features more intense pest management, with frequent spraying for anthracnose and mixed spraying for tobacco budworm or Phytophthora blight. The incidences for no pesticide control in 2010, 2011, and 2012 were 91, 97.6, and 41.4%, respectively. Conversely, the incidences for the IPM treatment for those years were 7.6, 62.6, and 2%, and the yields from IPM-treated plots were 48.6 kg, 12.1 kg, and 48.8 kg. The incidence and yield in the IPM-treated plots were almost the same as those of the periodic treatment except in 2011, in which no unnecessary sprays were given, meaning that the IPM control was quite successful. From reviewing eight years of field work, sophisticated forecasts that optimize pesticide spray timing reveal that reliance on pesticides can be reduced without compromising yield. Eco-friendly strategies can be implemented in the pest management of hot pepper.

• Annals of Clinical Neurophysiology
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• v.13 no.1
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• pp.21-25
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• 2011

Periodic lateralized epileptiform discharges (PLEDs) had been debated whether it is ictal or non-ictal phenomenon. As most of PLEDs occur in patients with acute structural lesions, some epileptologists prefer PLEDS as a non-ictal phenomenon, rather an obscure epiphenomenon of etiological diseases. But, almost half of the patients with PLEDs do not have acute structural lesions in the brain and metabolic disorders or old CNS lesions may cause PLEDs and even more, no brain lesion was identified in some patients. There are many data supporting PLEDs as ictal phenomena. Occurrence of PLEDs usually accompanied by decreased mentality and is improved as PLEDs disappeared. Current SPECT study showed marked hyperperfusion in the lesion side of PLEDs, that is striking evidence of PLEDs as ictal phenomena. Also careful review of EEG with PLEDs revealed it is a dynamic process rather than a static state. Despite of these evidences, as PLEDs are an end-stage of animal status epilepticus models, it may be a transition of ictal to interictal state.

• Membrane and Water Treatment
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• v.11 no.4
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• pp.295-302
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• 2020

In this paper, theoretical approach with applications of the periodic wave solutions in an elastic material is applied by study the effect of initial stress, and rotation, on the radial displacement and the corresponding stresses in non-homogeneous orthotropic material. An Analytical solution for the elastodynamic equation has obtained concerning the component of displacement. The variations of stresses and displacements have shown graphically. Comparisons with previously published results in the absence of initial stress, rotation and non-homogeneity have made. Finally, numerical results have given and illustrated graphically for each case considered.

• Sleep Medicine and Psychophysiology
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• v.15 no.1
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• pp.17-24
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• 2008

Periodic leg movements during sleep (PLMS) are best described as repetitive stereotypical movements of the lower extremities characterized by dorsiflexion of the ankle, dorsiflexion of the toes and a partial flexion of the knee and sometimes the hip. The prevalence of PLMS is about 5-11% in adults and is predicted much higher than previously surveyed. They are also frequently found in various sleep disorders, several disorders not primarily affecting sleep, and patients taking psychiatric medications. Although they are rarely found in children, they are common findings in children referred to a pediatric sleep laboratory. The pathophysiology is strongly associated with decline of central dopaminergic function and closely related to arousal system during sleep. Benzodiazepines, levodopa, dopamine agonists and opioids are generally recommended for treatment but more controlled studies on the effectiveness are needed.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.26 no.3
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• pp.227-231
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• 2013

Electrodeionization is a hybrid separation process of electrodialysis and ion exchange to produce high purity water under electric field. This article provides a fabrication result of hole patterned metal electrode for elecrodeionization system. The hole patterns have been fabricated by nanosphere lithography (NSL). The technique utilizes the self-assembled nanospheres as lens-mask patterns and collimated laser beam source. The hole patterns have a periodic array structure. The images of hole pattern on metal electrode prepared were observed by SEM. We believe that the periodic hole patterned metal electrode structure is a useful device applicable for metal mat electrode in electrodeionization system.