• The Korean Journal of Nuclear Medicine Technology
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• v.15 no.1
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• pp.121-125
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• 2011

Purpose: The DNA-type virus HBV, discovered by D. Dane and others in 1976, is approximately 42nm big and known as the main cause of liver-related diseases around the world. HBsAg has 4 kinds of subtypes including adw, adr, ayw and ayr and besides common antigen factor a, there are d, y, r, w. From the methods of serologically testing HBV, IRMA, EIA and CLIa were developed for testing HBsAg and are being used in examining the surface antigen of HBV. In this study, among the methods for testing HBV, the recently developed RIAKEY Ultrasensitive HBsAg IRMA kit's sensitivity level and performance in detection of mutant forms were measured and compared with CLIA. Materials and methods: Two certified reference materials, which are WHO 1st International Standard 1985(80/549) and WHO 2nd International Standard 2003(00/588. subtype adw2, genotypeA), were used in the examination and the sensitivity level was measured by diluting these materials from 0.08 IU/ml to 0.005 IU/ml. The materials for examining the detection of mutant forms included 9 kinds of subtype 'ad' and one kind of subtype 'ay' purchased from DSI company. Also, with the use of positive and negative samples, they was compared with CLIA. Result: Ultrasensitive HBsAg kit based on IRMA method showed the detection of up to 0.01 IU/ml not only for WHO 1st International Standard 1985(80/549) but also for WHO 2nd International Standard 2003(00/588. subtype adw2, genotypeA) and the sensitivity level was measured as 0.01 IU/ml by WHO standard. In testing the performance for detection of mutant forms, the 9 kinds of subtype 'ad' and one kind of subtype 'ay' mutant materials were detected, demonstrating the capacity of detecting various types of mutant forms. Conclusions: With the clinical importance of sensitivity level and performance in detection of mutant forms increasing in the field of HBsAg diagnosis, the examination of IRMA's effectiveness using RIA method in the aspects of the sensitivity level and performance in detection of mutant forms was carried out and its result is as follows. The sensitivity level was measured as 0.01 IU/ml by WHO standard and it was possible to measure various types of mutant forms with high sensitivity. Thus it is suggested that more speedy and accurate reports could be produced from a nuclear medicine laboratory for clinical practitioners requiring results of various situations.

• The Korean Journal of Blood Transfusion
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• v.23 no.2
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• pp.152-161
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• 2012

Background: Since Jan. 2012, for performance evaluation of viral reagents, analysis of domestic samples has been recommended in order to obtain approval from the KFDA when they are first introduced to Korea. This regulation requires the standard domestic materials driven from locally infected samples. We tried manufacturing the plasma working standards of HBV, HCV, and HIV NAT using a mixed titer of viral loads. Methods: Forty three HBV DNA positive plasmas, 25 HCV RNA positive plasmas, and 26 HIV RNA positive plasmas were evaluated according to viral load and genotype. Several plasma units, which had high-titer viral loads and the common viral genotypes in Korea, were selected as the source materials for each viral standard. To adjust the appropriate concentration based on the detectable range of variable viral reagents, the source plasma was diluted to several concentrations, divided into small vials, and analyzed for quantification. Results: The 13 plasma working standards, which had variable viral loads for the mixed titer performance panel of HIV, HCV, and HBV NAT, were produced. Conclusion: These national standard materials were first produced in order to supply the mixed titer performance panel for the viral NAT reagent of the level IV transfusion related high-risk group in Korea.

• Korean Journal of Construction Engineering and Management
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• v.24 no.4
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• pp.3-13
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• 2023

The purpose of this study is to compare and analyze the performance and work productivity of wet type pavement cutters and sludge suction type pavement cutters (hereinafter referred to as automatic pavement cutters) developed to reduce scattering dust. We first investigated the development status of wet type manual pavement cutters that are mainly used in Korea and automatic pavement cutters, and analyzed the pavement cutting work in detail. And the standard cutting performance was derived by measuring the cutting time by depth by applying the two equipment to the test bed under the same conditions. However, there is a limitation that the data measured in the test bed does not reflect the various variables of the actual pavement cutting site. Therefore, in this study, data was collected through field surveys, and the correlation between cutting distance and time was analyzed, and then a model for calculating the productivity of pavement cutters was presented through simple regression analysis. As a result of comparative analysis of the values derived from the regression equation with the standard cutting performance derived from the test bed, the cutting performance derived through the regression equation showed a similar trend to the standard cutting performance. Finally, we verified the usability of the automated pavement cutter developed by qualitatively analyzing three tasks that are difficult to measure quantitatively but affect productivity.

• Korean Journal of Radiology
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• v.24 no.8
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• pp.729-738
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• 2023

Objective: When multiple surveillance mammograms are performed within an annual interval, the current guidance for oneyear follow-up to determine breast cancer status results in shared follow-up periods in which a single breast cancer diagnosis can be attributed to multiple preceding examinations, posing a challenge for standardized performance assessment. We assessed the impact of using follow-up periods that eliminate the artifactual inflation of second breast cancer diagnoses. Materials and Methods: We evaluated surveillance mammograms from 2007-2016 in women with treated breast cancer linked with tumor registry and pathology outcomes. Second breast cancers included ductal carcinoma in situ or invasive breast cancer diagnosed during one-year follow-up. The cancer detection rate, interval cancer rate, sensitivity, and specificity were compared using different follow-up periods: standard one-year follow-up per the American College of Radiology versus follow-up that was shortened at the next surveillance mammogram if less than one year (truncated follow-up). Performance measures were calculated overall and by indication (screening, evaluation for breast problem, and short interval follow-up). Results: Of 117971 surveillance mammograms, 20% (n = 23533) were followed by another surveillance mammogram within one year. Standard follow-up identified 1597 mammograms that were associated with second breast cancers. With truncated follow-up, the breast cancer status of 179 mammograms (11.2%) was revised, resulting in 1418 mammograms associated with unique second breast cancers. The interval cancer rate decreased with truncated versus standard follow-up (3.6 versus 4.9 per 1000 mammograms, respectively), with a difference (95% confidence interval [CI]) of -1.3 (-1.6, -1.1). The overall sensitivity increased to 70.4% from 63.7%, for the truncated versus standard follow-up, with a difference (95% CI) of 6.6% (5.6%, 7.7%). The specificity remained stable at 98.1%. Conclusion: Truncated follow-up, if less than one year to the next surveillance mammogram, enabled second breast cancers to be associated with a single preceding mammogram and resulted in more accurate estimates of diagnostic performance for national benchmarks.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.3 s.234
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• pp.409-416
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• 2005

We need to develop a on-line thermal performance analysis system for nuclear power plant to determine performance status and heat rate of turbine cycle. We have developed PERUPS(PERformance Upgrade System) to aid the effective performance analysis of turbine cycle. Procedures of performance calculation are improved using several adaptations from standard calculation algorithms based on PTC(Performance Test Code). Robustness in the on-line performance analysis is increased by verification & validation scheme for measured input data. The system also provides useful web interfaces for performance analysis such as graphic heat balance of turbine cycle and components, turbine expansion lines, automatic generation of analysis report. The system was successfully applied for YongGwang nuclear plant unit #3,4.

• Nuclear Engineering and Technology
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• v.37 no.2
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• pp.167-176
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• 2005

We developed the PERUPS system to aid the on-line performance analysis for the turbine cycle of the YongGwang 3 and 4 nuclear power plants. Procedure of measurement validation is included in the performance calculation to obtain heat balance. Precision of on-line performance calculation is increased via practical modifications of standard calculation algorithms based on the PTC (Performance Test Code). The proposed system also provides useful Web-based aids for performance analysis, including performance data management, a graphic viewer for heat balance and turbine expansion lines, and synthesized reports of performance.

• 한국기계연구소 소보
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• s.9
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• pp.183-191
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• 1982

This report describes the analysis method of the full-scale propulsive performance by using the data of model test and the full-scale speed trial. The model test data were analyzed by the computer program "PPTT" based on "1978 ITTC Performance Prediction Method for Single Screw Ships." Also the full-scale speed trial data were analyzed by the computer program "SSTT" based on the newly proposed “SRS-KIMM Standard Method of Speed Trial Analysis." An analysis of model and full-scale test data was carried out for a 60.000 DWT Bulk Carrier and the correlation between model and full-scale ship was stuied.

• Proceedings of the Korea Concrete Institute Conference
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• 2004.05a
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• pp.664-667
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• 2004

It may have to establish the definite standard for performance evaluation basis about cementitious waterproofing material in job site that applied the method of construction formed cement waterproof course on concrete surface In present paper shows the effective selection method of waterproof layer of optimum thickness for economic performance as evaluating of the need thickness on waterproof property of penetrating waterproofing material.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 1990.10a
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• pp.91-98
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• 1990

This paper reviews the previous researches related to the effects of whole-body vibration on human performance. The physiological effects of vibration were reviewed in the first part, and the effects of vibration on vision and manual control performance were discussed. the relationships between vibration and ride quality were also discussed. ISO-2631 was briefly reviewed, and cautions and limitations were discussed to avoid misinterpretations when we accomodate Korean population to this standard. Further researches were recommended to get better understanding of response characteristics of Korean to whole-body vibration.

• Proceedings of the IEEK Conference
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• 1999.06a
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• pp.729-732
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• 1999

In this paper. we propose a system model and the associated control method for long distance connection using the High Performance Serial Bus, IEEE 1394. Though IEEE 1394-1995 Standard has connection distance limit of 4.5m, our proposed system can extend the limit further even without degrading network performance. And the current systems using IEEE 1394 don't have to make any change to use the proposed system.