• Title/Summary/Keyword: Pearson System

Search Result 596, Processing Time 0.027 seconds

Association between Chemotherapy-Response Assays and Subsets of Tumor-Infiltrating Lymphocytes in Gastric Cancer: A Pilot Study

  • Lee, Jee Youn;Son, Taeil;Cheong, Jae-Ho;Hyung, Woo Jin;Noh, Sung Hoon;Kim, Choong-Bai;Park, Chung-Gyu;Kim, Hyoung-Il
    • Journal of Gastric Cancer
    • /
    • v.15 no.4
    • /
    • pp.223-230
    • /
    • 2015
  • Purpose: The purpose of this pilot study was to evaluate the association between adenosine triphosphate-based chemotherapy response assays (ATP-CRAs) and subsets of tumor infiltrating lymphocytes (TILs) in gastric cancer. Materials and Methods: In total, 15 gastric cancer tissue samples were obtained from gastrectomies performed between February 2007 and January 2011. Chemotherapy response assays were performed on tumor cells from these samples using 11 chemotherapeutic agents, including etoposide, doxorubicin, epirubicin, mitomycin, 5-fluorouracil (5-FU), oxaliplatin, irinotecan, docetaxel, paclitaxel, methotrexate, and cisplatin. TILs in the tissue samples were evaluated using antibodies specific for CD3, CD4, CD8, Foxp3, and Granzyme B. Results: The highest cancer cell death rates were induced by etoposide (44.8%), 5-FU (43.1%), and mitomycin (39.9%). Samples from 10 patients who were treated with 5-FU were divided into 5-FU-sensitive and -insensitive groups according to median cell death rate. No difference was observed in survival between the two groups (P=0.216). Only two patients were treated with a chemotherapeutic agent determined by an ATP-CRA and there was no significant difference in overall survival compared with that of patients treated with their physician's choice of chemotherapeutic agent (P=0.105). However, a high number of CD3 TILs was a favorable prognostic factor (P=0.008). Pearson's correlation analyses showed no association between cancer cell death rates in response to chemotherapeutic agents and subsets of TILs. Conclusions: Cancer cell death rates in response to specific chemotherapeutic agents were not significantly associated with the distribution of TIL subsets.

An Analysis on the Contents and the Trend of Research of Performance Appraisal in Korea (인사고과에 관한 국내 간호연구 동향분석)

  • Jang, Keum-Seong;Kim, Nam-Young;Chung, Kyung-Hee;Kim, Yun-Min
    • Journal of Korean Academy of Nursing Administration
    • /
    • v.11 no.1
    • /
    • pp.89-104
    • /
    • 2005
  • Purpose: The authors reviewed researches related to performance appraisal(32 researches), in order to identify the direction for future research and to establish a credible performance appraisal system. Method: Almost all of the theses and research published in 9 major journals of nursing in korea were reviewed. Results: Most of research(84.4%) were theses and all researches were used to non-experimental design; survey 81.3%, methodological research 15.6%, review 3.1%. The major subjects of study were appraisees and appraisers. Psychosocial data collection which only used questionnaire were 81.3% and carried out interview(12.5%) and delphi-method(3.1%). Data analysis methods were used frequency 78.1%, t-test 62.5%, mean/SD 59.4%, Pearson's correlation 50%, and Cronbach α 50%. Appraisal tool used or developed in studies was graphic rating scales in nine studies and ran parallel with forced distribution in 2. Also, MBO and BSC were developed. Total number of korean terms in performance measurement were 11, and english terms 15. The tendency of the terms was toward performance appraisal or evaluation. Conclusion: In the light of results, we expect development of corporate appraisal tool that can evaluate nurse competence and performance. Total performance management system also should be established.

  • PDF

Apical foramen morphology according to the length of merged canal at the apex

  • Kim, Hee-Ho;Min, Jeong-Bum;Hwang, Ho-Keel
    • Restorative Dentistry and Endodontics
    • /
    • v.38 no.1
    • /
    • pp.26-30
    • /
    • 2013
  • Objectives: The aim of this study was to investigate the relationship between the apical foramen morphology and the length of merged canal at the apex in type II root canal system. Materials and Methods: This study included intact extracted maxillary and mandibular human premolars (n = 20) with fully formed roots without any visible signs of external resorption. The root segments were obtained by removing the crown 1 mm beneath the cementum-enamel junction (CEJ) using a rotary diamond disk. The distance between the file tip and merged point of joining two canals was defined as Lj. The roots were carefully sectioned at 1 mm from the apex by a slow-speed water-cooled diamond saw. All cross sections were examined under the microscope at ${\times}50$ magnification and photographed to estimate the shape of the apical foramen. The longest and the shortest diameter of apical foramen was measured using ImageJ program (1.44p, National Institutes of Health). Correlation coefficient was calculated to identify the link between Lj and the apical foramen shape by Pearson's correlation. Results: The average value of Lj was 3.74 mm. The average of proportion (P), estimated by dividing the longest diameter into the shortest diameter of the apical foramen, was 3.64. This study showed a significant negative correlation between P and Lj (p < 0.05). Conclusions: As Lj gets longer, the apical foramen becomes more ovally shaped. Likewise, as it gets shorter, the apical foramen becomes more flat shaped.

The Examination of Reliability of Lower Limb Joint Angles with Free Software ImageJ

  • Kim, Heung Youl
    • Journal of the Ergonomics Society of Korea
    • /
    • v.34 no.6
    • /
    • pp.583-595
    • /
    • 2015
  • Objective: The purpose of this study was to determine the reliability of lower limb joint angles computed with the software ImageJ during jumping movements. Background: Kinematics is the study of bodies in motion without regard to the forces or torques that may produce the motion. The most common method for collecting motion data uses an imaging and motion-caption system to record the 2D or 3D coordinates of markers attached to a moving object, followed by manual or automatic digitizing software. Above all, passive optical motion capture systems (e.g. Vicon system) have been regarded as the gold standards for collecting motion data. On the other hand, ImageJ is used widely for an image analysis as free software, and can collect the 2D coordinates of markers. Although much research has been carried out into the utilizations of the ImageJ software, little is known about their reliability. Method: Seven healthy female students participated as the subject in this study. Seventeen reflective markers were attached on the right and left lower limbs to measure two and three-dimensional joint angular motions. Jump performance was recorded by ten-vicon camera systems (250Hz) and one digital video camera (240Hz). The joint angles of the ankle and knee joints were calculated using 2D (ImageJ) and 3D (Vicon-MX) motion data, respectively. Results: Pearson's correlation coefficients between the two methods were calculated, and significance tests were conducted (${\alpha}=1%$). Correlation coefficients between the two were over 0.98. In Vicon-MX and ImageJ, there is no systematic error by examination of the validity using the Bland-Altman method, and all data are in the 95% limits of agreement. Conclusion: In this study, correlation coefficients are generally high, and the regression line is near the identical line. Therefore, it is considered that motion analysis using ImageJ is a useful tool for evaluation of human movements in various research areas. Application: This result can be utilized as a practical tool to analyze human performance in various fields.

Assessment of Productivity and Foodservice Management Practices in Elementary School Foodservices Located in Seoul and KangNung (서울.강릉지역 초등학교 급식소의 급식생산성 분석)

  • 김은경;김은미;강명희;홍완수
    • Korean journal of food and cookery science
    • /
    • v.14 no.1
    • /
    • pp.76-83
    • /
    • 1998
  • The purpose of this study was to evaluate the foodservice management practices and productivity in elementary schools in order to provide basic information for an efficient food service management. This approach was achieved using a variety quantitative and qualitative information including general foodservice management, managerial and operational factors, and the productivity in elementary school foodservice systems. The labor productivity in 28 school foodservice system was assessed and related to a number of influencing variables within the system. The productivity measurement was based upon the total meal equivalents as a ratio of the total direct and non-direct labor hours required to prepare these meals. Twenty-eight elementary schools located in Seoul and Kangnung were surveyed to get data for the variables. Questionnaire and a survey form were mailed. Statistical methods used in this study were descriptive analysis, $\chi$$^2$-test, 1-test and one-way ANOVA analysis. Elementary schools in Seoul were all located in urban areas, whereas elementary schools in Kangnung were in urban areas (40.0%), provincial areas (40.0%) and in isolated areas (20.0%). Total average number of meals including children and staff was 928.2${\pm}$ 650.0 with a yery significant difference (p<0.001) between Seoul and Kangnung. The average cost of school meal in Seoul and Kangnung were 1191.0 won and 1526.2 won, respectively. The result of Pearson Correlation analysis indicated that labor cost per meal, 1-week meal equivalents and meal equivalents per labor were significantly correlated with the productivity.

  • PDF

A Reliability Study of Sit-to-walk for Dynamic Balance Assessment in Stroke Patient (뇌졸중환자의 동적 균형 평가를 위한 sit-to-walk의 신뢰도 연구)

  • Kim, Da-Yeon;Choi, Jong-Duk;Ki, Kyong-Il
    • The Journal of Korean Physical Therapy
    • /
    • v.25 no.5
    • /
    • pp.303-310
    • /
    • 2013
  • Purpose: The purposes of this study were to evaluate the correlation of clinical tools for assessment of balance and ability of gait, in order to discriminate the phases of sit-to-walk movement of patients with stroke using the motion analysis system, and to investigate the reliability of the phase of sit-to-walk movement according to functional ability of patients with stroke. Methods: Twenty -one patients participated (men 17, women 4) in this study. Sit-to-walk movement of all patients was recorded by the motion analysis system. Berg Balance Scale, Timed Up and Go test, Functional Reach Test, 10 meter Walk Timed Test, and Performance-Oriented Mobility Assessment were used as functional assessment tools. Results: The results of this study showed significant correlation between the phase I, II, IV and total phase duration of sit-to-walk movement and functional assessment tools. In addition, the intraclass correlation coefficient (ICC) showed high reliability in accordance with the functional ability of patients with stroke (Pearson's r 0.93 to 1.00). Conclusion: In conclusion, there is high reliability between measures of the phase of sit-to-walk movement of chronic stroke patients and the clinical assessment tool. Results of this study suggest that measurement of the phase of sit-to-walk movement can be used significantly as an intervention and a clinical tool for patients with stroke.

Predictors of Total Quality Management in Health-Care Organizations (의료기관에서의 종합적 품질경영과 관련된 변인분석)

  • Tak, Ki-Chun;Yoo, Kyu-Soo
    • Korea Journal of Hospital Management
    • /
    • v.6 no.3
    • /
    • pp.46-68
    • /
    • 2001
  • The study was to examine the relationships among those variables related to total quality management and to reveal those variables affecting total quality management in Health-Care Organizations. To study the relationship, a questionaire was designed and sent to 220 hospitals of which the number of beds is over 200 beds. Out of 660 questionaire, 263 questionaire were collected. Data analysis were conducted by using t-test, ANOVA, Pearson correlation coefficients and stepwise multiple regression. The result were as follows: 1. TQM was significantly different according to activities of QI, department of QI, age, and position. 2. Leadership was significantly different according to activities of QI, department of QI, age, and position. 3. Significant differences in the level of satisfaction of employee were found according to activities of QI, department of QI, age, position, and duration of employ. 4. Significant differences in the level of participation of employee were found according to activities of QI, department of QI, and position. 5. Education trainning was significantly different according to amount of bed, activities of QI, department of QI, level of education, kind of job, and position. 6. Medical technique was significantly different according to activities of QI, department of QI, and position. 7. Quality of work was significantly different according to activities of QI, department of QI, age, and position. 8. Significant differences in the level of investigation's system in satisfaction of client were found according to activities of QI, department of QI, kind of job, and position. 9. Positive correlations were observed between TQM and those variables related to TQM. 10. TQM was significantly predicted by the level of satisfaction of employee(40.9%), participation of employee(7.0%), investigation's system in satisfaction of client(2.7%), leadership(1.4%), and medical technique(1.1%), respectively.

  • PDF

Safety and Health Perceptions in Work-related Transport Activities in Ghanaian Industries

  • Atombo, Charles;Wu, Chaozhong;Tettehfio, Emmanuel O.;Nyamuame, Godwin Y.;Agbo, Aaron A.
    • Safety and Health at Work
    • /
    • v.8 no.2
    • /
    • pp.175-182
    • /
    • 2017
  • Background: With the recent rapid industrialization, occupational safety and health (OSH) has become an important issue in all industrial and human activities. However, incidents of injuries and fatality rates in the Ghanaian industry sector continue to increase. Despite this increase, there is no evidence regarding the element of OSH management in transport activities in Ghanaian industries. Thus, this study aims to examine the perceptions regarding the importance of safety and health in work-related transport activities in Ghanaian industries. Methods: A survey data collection technique was used to gather information on best safety practices over a 5-month period. We randomly selected 298 respondents from industries to answer structured questionnaires. The respondents included drivers, transport managers, and safety engineers. Standard multiple regression model and Pearson product-movement correlation were used to performed the analysis. Results: The result shows that for interventions to improve safety and health, concentration has been on drivers' safety practice with less attention to safe driving environments and vehicle usage. Additionally, the respondents are aware of the importance of OSH in transport activities, but the level of integration does not measure up to the standard to reduce operational accidents and injuries. Finally, strong commitment to changing unsafe practices at all levels of operations appears to be the effective way to improve safety situations. Conclusion: OSH culture is not fully complied in industries transport activities. This study, therefore, supports the use of safety seminars and training sessions for industry workers responsible for transport operations for better integration of safety standards.

Relationship of Perception of Clinical Ladder System with Professional Self-Concept and Empowerment based on Nurses' Clinical Career Stage (간호사의 임상경력단계에 따른 경력개발제도 인식과 전문직 자아개념, 임파워먼트와의 관계)

  • Min, A-Ri;Kim, In Sook
    • Journal of Korean Academy of Nursing Administration
    • /
    • v.19 no.2
    • /
    • pp.254-264
    • /
    • 2013
  • 연구목적: 본 연구는 간호사의 임상경력단계에 따른 경력개발제도에 대한 간호사의 인식을 파악하고, 경력개발제도에 대한 인식, 전문직 자아개념과 임파워먼트와의 관계를 파악하여 간호사 경력개발제도의 개선의 근거 마련하고 전문직 자아개념과 임파워먼트의 증대 방안 모색을 통한 인적자원관리에 기여하고자 시도 된 서술적 상관관계 연구이다. 연구방법: 서울시 소재 일 상급종합병원에서 근무하는 중환자실, 수술실, 응급실 간호사 162명을 대상으로 설문지를 이용하여 경력개발제도에 대한 인식, 전문직 자아개념, 임파워먼트를 측정하였다. 수집된 자료는 SPSS WIN 18.0 프로그램을 활용하여 서술적 통계, t-test, ANOVA, Pearson's Correlation Coefficient, Multiple linear Regression을 시행하였다. 연구결과: 간호사의 임상경력단계에 따른 경력개발제도에 대한 인식은 전임 2 간호사가 신입 간호사, 일반 간호사, 전임 1 간호사보다 높은 인식을 가지고 있었다. 경력개발제도에 대한 인식과 전문직 자아개념, 임파워먼트에는 통계적으로 유의한 양의 상관관계가 있었다. 다중회귀분석을 실시한 결과 경력개발제도에 대한 전반적 이해, 경력개발제도에 대한 기대효과, 최종학력, 임상경력단계가 전문직 자아개념의 42% 설명하는 것으로 나타났고, 경력개발제도에 대한 전반적 이해, 전문적 활동 참여에 대한 인식, 경력개발제도에 대한 기대효과, 임상경력단계가 임파워먼트를 42% 설명하였다. 결론: 전문직 자아개념과 임파워먼트에 영향을 미친 변수로 나타난 경력개발제도에 대한 인식을 향상시킬 수 있는 방안을 개발하여 적용을 통한 효과 검증이 요구되며, 간호 관리자들의 제도 운영과 관련된 장애요인의 파악 및 세심한 제도 개선이 필요하다.

A study on dental hygienists' knowledge and attitude towards medical related laws (치과위생사의 의료관련법에 대한 지식 및 태도에 관한 연구)

  • Jang, Yun-Jung
    • Journal of Korean society of Dental Hygiene
    • /
    • v.17 no.2
    • /
    • pp.295-305
    • /
    • 2017
  • Objectives: This study was performed to provide a reference base to establish foundation for education about dental hygienist-related medical law and introduction of the system. Methods: A survey was conducted on 210 dental hygienists working at a dental clinic/ hospital in Jeollado. Data were analysed through chi-square test, one-way ANOVA, independent t-test, and Pearson's correlation analysis using SPSS 21.0 program. The study instruments included general characteristics of the subjects, knowledge on laws related to dental hygiene, attitude towards dental hygienist-related medical laws, level of understanding of medical related laws, and medical dispute educational hours. Results: The knowledge of dental hygienist-related medical law was high in dental hygienists aged 25 years and younger and with less than 3 years of clinical experience (p<0.05). The attitude towards the law was low in age of younger than 25 years, a three year college degree, a job position as a staff member, more than 5 years of work experience at present work place, and less than 3 years of clinical experience (p<0.05). Understanding of medical related laws was high in clinical staff members and with less than 3 years of clinical experience (p<0.05). Educational needs for medical dispute prevention was high in a job position as a staff member, low level of attitude towards dental hygienist-related medical law, and no attainment of education on medical dispute (p<0.05). Conclusions: The above results demonstrate that education and public relations about laws related with dental hygiene practice are essential. It is imperative to establish a systematic and bureaucratic legal system to prevent dental malpractice.