• 한국약용작물학회지
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• 제18권6호
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• pp.398-404
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• 2010

Complementary and alternative medicines are considered as a promising research field to develop new therapies for various allergic diseases. In this study, we investigated the anti-allergic effect of Agrimonia pilosa Ledeb (AP) by using passive cutaneous anaphylaxis in mice and its mechanism of action in mast cells. The extract of AP reversibly inhibited degranulation in RBL-2H3 cells and bone marrow-derived mast cells (BMMCs). AP also suppressed the passive cutaneous anaphylaxis inducing by IgE and antigen (Ag) in a dose-dependent manner. In the study to find its mechanism of action, AP inhibited the phosphorylation of Syk kinase, a pivotal protein which is regulated by Src-family kinase for activation of mast cells. In addition, AP also suppressed activation of Akt and Erk1/2 that are critical for the production of cytokines in mast cells. The results strongly suggest that AP exerts anti-allergic activity in vitro and in vivo through the inhibition of activation of Syk in mast cells.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.1559-1564
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• 2003

In this paper, a control method is presented to improve performance of haptic display on a passive haptic device equipped with passive actuators. In displaying a virtual wall with the passive haptic device, an unstable behavior occurs with excessive actions of brakes due to the time delay mainly arising from the update rate of the virtual environment and force approximation originated from the characteristics of the passive actuators. The previous T.D.P.C. (Time Domain Passivity Control) method was not suitable for the passive haptic device, since a programmable damper used in the previously introduced T.D.P.C. method easily leads to undesirable behaviors. A new passivity control method is evaluated with considering characteristics of the passive device. First, we propose a control method which is designed under the analysis of the passive FME (Force Manipulability Ellipsoid). And then a passivity control scheme is applied to the proposed control method. Various experiments have been conducted to verify the proposed method with a 2-link mechanism.

• 대한기계학회논문집A
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• 제27권11호
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• pp.1831-1839
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• 2003

This paper deals with design and control of passive multiple trailer systems fer practical applications. Due to cost and complexity of trailer mechanism, passive systems are preferred to active systems in this research. The control objective is to minimize trajectory tracking errors of passive multiple trailers. Three types of passive trailer systems-direct-hooked, three-point, and off-hooked- are discussed in this paper. Trajectory tracking performance and stability issues under constant velocity motion are carried out for three types. Various simulations and experiments have been also performed for these three types. It is shown that the proposed off-hooked trailer system produces better tracking performance than the other types.

• International Journal of Control, Automation, and Systems
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• 제2권3호
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• pp.289-297
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• 2004

This paper deals with the design and control of passive multiple trailer systems for practical applications. Due to the cost and complexity of the trailer mechanism, passive systems are preferred to active systems in this research. The design and control objective is to minimize the trajectory tracking errors occurring in passive multiple trailers. Three sorts of passive trailer systems, off-hooked, direct-hooked, and three-point, are discussed in this paper. Trajectory tracking performance and stability issues under constant curvature reference trajectories are investigated for these three types. As well, various simulations and experiments have been performed for each type. It is shown that the proposed off-hooked trailer system produces a tracking performance that is superior to the others.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2012년도 춘계학술대회 논문집
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• pp.971-972
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• 2012

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2009년도 추계학술대회 논문집
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• pp.169-170
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• 2009

• 대한기계학회:학술대회논문집
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• 대한기계학회 2002년도 학술대회지
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• pp.435-438
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• 2002

In this study, a new passive aerodynamic control method is proposed. Control plate which is oscillated by TMD-like mechanism makes flutter stabilizing airflow. Effectiveness of proposed model is verified by experimental and analytical study. In addition, various parameters of the proposed system are investigated. Applicability to long span bridge is also examined. According to the research results, proposed model is very effective in suppressing flutter, and it also shows remarkable robustness.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1995년도 추계학술발표회논문집(1)
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• pp.358-363
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• 1995

A study on passive cooling systems for concrete containment of advanced pressurized water reactors has been performed. The proposed passive containment cooling system (PCCS) consist of (1) condenser units located inside containment, (2) a steam condensing pool outside containment at higher elevation, and (3) downcommer/riser piping systems which provide coolant flow paths. During an accident causing high containment pressure and temperature, the steam/air mixture in containment is condensed on the outer surface of condenser tubes transferring the heat to coolant flowing inside tubes. The coolant transfers the heat to the steam condensing pool via natural circulation due to density difference. This PCCS has the following characteristic: (1) applicable to concrete containment system, (2) no limitation in plant capacity expansion, (3) efficient steam condensing mechanism (dropwise or film condensation at the surface of condenser tube), and (4) utilization of a fully passive mechanism. A preliminary conceptual design work has been done based on steady-state assumptions to determine important design parameter including the elevation of components and required heat transfer area of the condenser tube. Assuming a decay power level of 2%, the required heat transfer area for 1,000MWe plant is assessed to be about 2,000 ㎡ (equivalent to 1,600 of 10 m-long, 4-cm-OD tubes) with the relative elevation difference of 38 m between the condenser and steam condensing pool and the riser diameter of 0.62 m.

• Smart Structures and Systems
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• 제24권1호
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• pp.95-110
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• 2019

The semi-active impact damper (SAID) is proposed to improve the damping efficiency of traditional passive impact dampers. In order to investigate its damping mechanism and vibration control effects on realistic engineering structures, a 20-story nonlinear benchmark building is used as the main structure. The studies on system parameters, including the mass ratio, damping ratio, rigid coefficient, and the intensity of excitation are carried out, and their effects both on linear and nonlinear indexes are evaluated. The damping mechanism is herein further investigated and some suggestions for the design in high-rise buildings are also proposed. To validate the superiority of SAID, an optimal passive particle impact damper ($PID_{opt}$) is also investigated as a control group, in which the parameters of the SAID remain the same, and the optimal parameters of the $PID_{opt}$ are designed by differential evolution algorithm based on a reduced-order model. The numerical simulation shows that the SAID has better control effects than that of the optimized passive particle impact damper, not only for linear indexes (e.g., root mean square response), but also for nonlinear indexes (e.g., component energy consumption and hinge joint curvature).

• 로봇학회논문지
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• 제11권4호
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• pp.193-204
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• 2016

This paper presents an anthropomorphic finger prosthesis for amputees whose proximal phalanx is mutilated. The finger prosthesis to be proposed is able to make the amputees to perform the natural motion such as flexion/extension as well as self-adaptive grasping motion as if normal human finger does. The mechanism of finger prosthesis with three degrees-of-freedom (DOFs) consists of two five-bar and one four-bar linkages. Two passive components composed of torsional spring and mechanical stopper and only one active joint are employed in order to realize an underactuation. Each passive component is installed into the five-bar linkage. In order to activate the finger prosthesis, it is required for the user to flex and extend the remaining proximal phalanx on the metacarpophalangeal (MCP) joint, not an electric motor. Thus the finger prosthesis conducts not only the natural motion according to his/her intention but also the grasping motion through the deformation of springs by the object for human finger-like behavior. In order to reveal the operation principle of the proposed mechanism, kinematic analysis is performed for the linkage design. Finally both simulations and experiments are conducted in order to reveal the design feasibility of the proposed finger mechanism.