• Journal of Environmental Health Sciences
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• v.42 no.6
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• pp.396-408
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• 2016

Objectives: The purposes of this study were to determine the relationship between the prevalence of allergic diseases and urinary cadmium concentration among children from six to 12 years of age, and to evaluate the association between cadmium in urine and other immunologically related factors in two elementary schools with different environmental conditions. Methods: Data on physician-diagnosed prevalence over the past 12 months and potential risk factors for allergic disease were collected from survey results drawn from 236 children living in different regions (central urban vs. suburban) from April to July in 2014 by an ISAAC questionnaire. We analyzed cytokine levels in serum through enzyme-linked immunosorbent assay and urinary cadmium concentration by use of inductively coupled plasma mass spectrometry. Results: Concentrations of urinary cadmium in suburban and central urban children were $0.11{\pm}0.11ug/L$, $0.14{\pm}0.17ug/L$, respectively (p>0.05). Results from the analysis of the t-test and chi-square test showed that urinary cadmium levels were positively associated with environmental factors (paternal smoking status, passive smoking, traffic volume and experiences of outdoor odors) and individual genetic factors (parental allergic disease). Cadmium concentrations in urine were also positively associated with the prevalence of allergic disease and immune-related cytokines (eosinophils, IgE, IL-5, IL-33, IL-17). Conclusion: This study suggests that genetic factors (parental history of allergic diseases), environmental factors, and regional status (suburban and central urban) should be considered as probable factors increasing the concentration of urinary cadmium, which has the potential to influence the allergic disease prevalence of school-age children.

• Journal of Nutrition and Health
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• v.51 no.2
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• pp.140-152
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• 2018

Purpose: Recently, there has been a worldwide increase in the prevalence of food allergies in children and it may cause nutritional imbalance and poor quality of life for growing children due to dietary restrictions. This study was conducted to quantitatively measure the life burden and related factors of mothers who are the primary caretakers of food-allergic children. Moreover, we generated data for use as a scientific basis for the development of a disease management program to reduce the burden on life from raising food-allergic children. Methods: Mothers of 2,005 children aged 2 years or older and enrolled in Seoul Metropolitan Atopy Free Schools in 2016 who have had diagnosis of food allergy in their lifetime were surveyed. The burden on life of parents with food-allergic children was measured using 17 questions from the Food Allergy Quality of Life-Parental Burden (FAQL-PB) questionnaire, and subjects were asked to respond with a scale of 1 ~ 7. Results: We analyzed the effects of sociodemographic factors of parents and children and the accompanying allergic disease factors on the lives of parents. The number of restricted food items due to food allergy of a child and accompanying diagnosis of atopic dermatitis had a positive (+) effect on the life burden of the parents. Conclusion: Accurate oral food challenge for food allergies should be administered to prevent excessive restriction of food intake. Moreover, efforts should be taken to prevent morbidity accompanying food allergy and relieve symptoms of asthma, allergic rhinitis and atopic dermatitis.

• Journal of the Korea Convergence Society
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• v.10 no.3
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• pp.355-362
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• 2019

The aim of this study was to identify factors affecting life satisfaction for adolescents with asthma or atopic dermatitis. Korean Child and Youth Panel Survey (KCYPS) Data in 2016 was used. The data were analyzed by Chi-square test, t-test, one-way ANOVA and stepwise multiple linear regression. In multiple stepwise regression analysis, less depression, higher resilience, higher self-esteem, more affectionate parenting behavior, lower age enhances the life satisfaction of adolescents with allergic disease. Educational program is necessary to improve the life satisfaction of adolescents with asthma or atopic dermatitis which is reflecting the result of this study.

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.9
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• pp.1387-1394
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• 2013

Allergies are one of the most common chronic diseases during childhood. While the prevalence of allergic disease in children is increasing dramatically, few studies have evaluated the risk and preventive factors related to this health condition, especially in South Korea. The purpose of this case-control study was to evaluate independent determinants of allergic disease, and to examine whether it is associated with growth and other health conditions in childhood. The current study included 209 cases and 311 age and sex-matched controls (fifth and sixth graders) residing in Daegu, South Korea. Environmental data was collected, including child and family histories of allergies, birth information, and reaction to weaning foods during infancy. In addition, current dietary habits (assessed by 2 day-24 hr food records), health conditions, and anthropometric data were obtained through questionnaires and student health check-ups at the school. Based on chi-square tests, cases had a significantly higher prevalence of having a disease at birth, an allergic reaction to weaning foods, frequent hospital visits, and frequent experiences of the common cold and digestive diseases. In addition, significantly more mothers had a higher education in the cases compared to controls. Based on multivariable conditional logistic regression analysis, factors significantly associated with greater odds for having allergies were parental (OR=21.42) and fraternal (OR=14.40) histories of allergies. The anthropometric measures showed that cases tended to be shorter in height and lighter in weight than the controls, but these differences were not statistically significant. These findings may indicate that current nutrient intakes may not be the only critical factor associated with delayed growth delay in the allergic group. A well-planned, large cohort study is warranted to confirm our findings in the future.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.4 no.1
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• pp.98-105
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• 1993

Objective ' The purpose of this study was to investigate the behavioral characteristics of children with allergic disease Method : In a population of 80 children who were registered at a pediatric allergic clinic in Kangnam St Mary's hospital, parents completed a standardized child behavior checklist (CBCL) to evaluate their children Clinical factors associated with allergy were examined in relation to the rated scores of CBCL Results : Allergic children were rated significantly more aggressive and delinquent, and less withdrawned on the CBCL rating when compared to the age- and sex-matched normal control children. Within the allergic population, children who had family history of allergic disease had higher scores of CBCL in hyperactivity and aggressive behavior than the children without family history. Conclusion : The results were discussed with the respect to familial traits of allergy and temperament as risk factors for the emergence of behavior problems in childhood allergy

• Journal of agricultural medicine and community health
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• v.34 no.2
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• pp.175-187
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• 2009

Objectives: This study was conducted to investigate whether joint effects between family allergy history and environmental tobacco smoke(ETS) by parents were associated with pediatric asthma and wheezing. Methods: The study objects of this study were 2301 element school students and their parents in an urban-rural areas of Gyeonggi-do. Pediatric asthma and wheezing were identified by measures of International Study of Asthma and Allergies in Childhood (ISAAC) questionnaires. We investigated history of parental allergy, ETS, and other socioeconomic status of both parent. Data were analyzed using logistic regression methods. Results: After adjusting other variables, children with maternal asthma history were more likely to be reported life time wheezing (OR: 3.79 95%CI:2.43-5.90), recent wheezing (OR:4.09 95%CI:2.28-7.38), and diagnostic asthma (OR:2.61 95%CI: 1.44-4.75). Paternal asthma history increasing risk of life time wheezing (OR 2.01 95%CI:1.19-3.38) and recent wheezing (OR:2.38 95%CI:1.24-4.56). Joint effect between parental allergy history and ETS significantly effected on child's life time wheezing and recent wheezing. The risks of life time wheezing (OR:2.47 95%CI:1.64-3.717) and recent wheezing (OR: 2.51 95%CI:1.34-4.69) were significantly higher than others without both factors. The risk of recent wheezing of children with maternal recent smoking and parental allergy history (OR:4.83 95%CI:1.89-12.33) was higher than their counterpart. Conclusions: The result of this study implies that children with family allergy history and passive smoking are more likely to be get asthma and wheezing than children with family allergy history and non-passive smoking. This study provide the object information to increase the efficiency of non-smoking campaign and education for decreasing pediatric asthma risk.