• 한국콘텐츠학회논문지
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• 제10권11호
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• pp.275-284
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• 2010

본 연구는 3-5세 아동을 대상으로 발달선별검사인 K-DDSTII, K-ASQ을 실시하여 발달지연 결과를 가진 하부검사와 가정환경 간의 관련성을 알아보았다. 연구결과, K-DDST에서는 가족환경 중 아버지의 나이와 개인사회성, 어머니의 나이와 교육력이 대동작과 통계적으로 차이가 있었다. 또한 K-ASQ에서는 의사소통과 성별, 출생순서와 부모의 교육력에서 통계적으로 유의한 차이가 있었으며, 문제해결과 출생순서, 그리고 하부검사 중 하나이상의 발달지연이 있는 경우는 성별과 출생순서와 유의미한 통계적 차이가 있었다. 본 연구결과 발달선별 검사 시에 가족환경에 관한 조사가 병행된다면 아동 발달에 대한 선별검사의 효율성을 높이는 방안의 하나일 수 있음을 제시 할 수 있을 것이다.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.116-116
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• 2017

Low-temperature is one of the environmental stress factors that affect plant growth and development and consequently limit crop productivity. The control of seed germination under low-temperature is organized by many genes which are called quantitative trait loci (QTLs). High germination rate for low-temperature is an important factor of growing rice. Previously, we identified a major QTL controlling low-temperature germinability in rice using 96 introgression lines (ILs) derived from a cross between Oryza rufipogon (Rufi) and the Korean japonica cultivar, 'Hwaseongbyeo (HS)'. A $BC_3F_7$ line (TR5) showed better low-temperature germinability than its recurrent parent. TR5 was crossed with HS to develop a segregating F2:3 populations for the target QTL. Six SSR markers polymorphic between HS and Rufi were used to screen and fine map the qLTG1. The qLTG1 on chromosome 1, which accounted for 55.5% of the total phenotypic variation, confirmed that Rufi allele enhanced the low-temperature germinability. Intervals between markers CRM16 and CRM15, four candidate genes were identified. The identified candidate genes, which are encoded by a protein of unknown function, showed their direct involvement on seed germination at low-temperature. To identify genes targeted by qLTG1, we investigated the expression profiles of these candidate genes and germination behavior of qLTG1 under different stress conditions and compared to HS, Rufi, and TR5 at $13{\pm}2^{\circ}C$ for 3 days after incubation. Furthermore, transgenic rice plants will also be developed to conduct a detailed investigation on low-temperature germinability. Hence, the QTL for low-temperature germinability would be useful in rice breeding programs especially in the development of lines possessing low-temperature germinability.

• Asian Pacific Journal of Cancer Prevention
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• 제14권10호
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• pp.5797-5804
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• 2013

In order to enhance the bioavailability of curcumin its conjugates with piperic acid and glycine were synthesized by esterifying the 4 and 4' phenolic hydroxyls, the sites of metabolic conjugation. Antiproliferative and apoptotic efficacy of synthesized conjugates was investigated in MCF-7 and MDA-MB-231 cell lines. $IC_{50}$ values of di-O-glycinoyl (CDG) and di-O-piperoyl (CDP) esters of curcumin were found to be comparable with that of curcumin. Both conjugates induced chromatin condensation fragmentation and apoptotic body formation. CDP exposure to MCF-7 cells induced apoptosis initiating loss of mitochondrial membrane potential (${\Delta}{\Psi}m$) followed by inhibition of translocation of transcription factor NF-${\kappa}B$ and release of Cytochrome-C. Reactive oxygen species (ROS) production was evaluated by fluorescent activated cell sorter. Change in ratio of Bcl2/Bclxl was observed, suggesting permeablization of mitochondrial membrane leading to the release of AIF, Smac and other apoptogenic molecules. DNA fragmentation as a hallmark for apoptosis was monitored by TUNEL as well as agrose gel electrophoresis. Thus, it was proven that conjugation does not affect the therapeutic potential of parent molecule in vitro, while these could work in vivo as prodrugs with enhanced pharmacokinetic profile. Pharmacokinetics of these molecules under in vivo conditions is a further scope of this study.

• 종양간호연구
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• 제11권3호
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• pp.186-192
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• 2011

Purpose: The primary prevention for cervical cancer, the human papilloma virus (HPV) vaccination, has been available in South Korea and its importance has been emphasized publicly. The purpose of this study was to investigate the knowledge regarding HPV vaccination and identify the factors associated with HPV vaccination in female university students. Methods: A sample of 200 women among university students in Seoul was asked to answer a questionnaire on HPV-related knowledge and attitude, and influencing factors on HPV vaccination. Results: Among the respondents, 12.0% were HPV vaccinated. Overall HPV-related knowledge was low, and knowledge was not different between the vaccinated and unvaccinated groups. The vaccinated group demonstrated a higher score on the knowledge about the place where people could receive HPV vaccination and the cost of the vaccination than that of the unvaccinated group. The major influencing factor on vaccination was the parent's recommendation and the major barrier for vaccination was the cost of the vaccination. Conclusion: A broadened public campaign is recommended to increase the knowledge and positive attitude towards HPV vaccination for university female students as well as their parents.

• 한국생활과학회지
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• 제13권1호
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• pp.63-73
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• 2004

This study examined the effects of perceived marriage conflict, mother's parenting and child's behavior problems on the child abuse. The sample consisted of 428 filth and sixth grade children. Statistical methods used for data analysis were Cronbach's alpha, factor analysis, Pearson's correlation, multiple regression and path analysis. Several major results found from the analysis were as follows. First, the more the child perceived the parent's marriage conflict, the mother's parenting was controlling and the child's behavior was externalized, the more the child was subjected to the physical and verbal abuses. The mother's controlling parenting behavior had a first direct influence on the physical abuse, and the marriage conflict on the verbal abuse. Second, the marriage conflict had direct and indirect positive effects on the physical and verbal abuses through the mother's affective and controlling parenting and the child's externalizing behavior problems. Third, the mother's controlling parenting had direct and indirect positive effects on the physical and verbal abuses through the child's externalizing behavior problems and. And mother's affective parenting had a direct negative effect on the physical and verbal abuses. Fourth, child's externalizing behavior problems had a direct positive effect on the physical and verbal abuse. Fifth, child's sex had an indirect effect on the physical and verbal abuses through mother's affective and controlling parenting. That is, boys were more exposed to the physical and verbal abuses, because mothers more controlled and less affected boys than girls.

• 대한지역사회영양학회지
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• 제14권5호
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• pp.545-555
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• 2009

School foodservice customers are likely to be tired of repeated cycle menus and their satisfaction for meals offered in school is inclined to be low. The menu variety is an important factor in increasing customer satisfaction. The purpose of this study was to investigate customer perspectives for applying rice based bread menus in order to add menu variety and promote using rice processed products in school foodservice. The questionnaire was distributed to 760 parent samples in elementary schools and 520 student samples in middle/high schools and a total of 665 and 387 usable data were collected, respectively. Food habits such as preference for cooking method, menu preference, food allergy and nutritional perspectives for menu and customer perception for rice based bread like quality, reliability, price, and purchasing convenience were investigated using 7 Likert scale. Also expected menu types applying rice based bread and offering frequency of rice bread menu were examined. Preference level for bread-based meals were moderate and students' preferences were slightly higher than parents. Menu types applying rice bread expected by middle/high school students were western food (49.4%), spaghetti (28.4%), set menu (13.7%), noodle (17.6%), Korean food (11.1%), Chinese food (10.9%) and porridge (4.5%). The most occupied rate was once in a week for expected offering frequency. Most respondents perceived that rice bread was more nutritive and qualitative than the wheat based one.

• 동의신경정신과학회지
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• 제21권4호
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• pp.99-112
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• 2010

Objectives : This study was to investigate the associations of Parent Stress Index(PS]). Way of Coping Checklist(WCC). and Diagnostic System of Oriental Medicine(DSOM) in mothers of elementary school children. Methods: In the study. K-PSI-SF. WCC. and DSOM were carried out on 202 mothers of O Oelementary school children during June. 2010. Cross tabulation analysis was used to verify the association of PSI. WCC and DSOM. Results: 1. The most common pathogenic factor was Dampness(濕) in total subjects. 2. The score of problem-focused coping methods showed significant difference in PSI grades. 3. The zp and sc10 of Qi deficiency(氣虛), Blood deficiency(血虛), Qi-Stagnation(氣滯), Insufficiency of Yang(陽虛), Heat(熱), Dampness(濕), Dryness(燥), Liver(肝), Heart(心), and Kidney(腎) showed significant difference in PSI grades. 4. The score of total PSI and PSI subscale had negative correlations with problem-focused coping methods 5. The score of total PSI had positive correlations with Qi-Stagnation (氣滯), Dampness(濕), Dryness(燥), Heart(心), and Kidney(腎) in total subjects. Conclusions : This study provides insights on associations of parenting stress coping methods and diagnostic system in Oriental Medicine. Furthermore, the study shows positive correlations among Qi-Stagnation (氣滯), Dampness(濕), Dryness(燥), Heart(心), Kidney(腎) and PSI, and negative correlations between PSI and Problem-focused coping methods, all with statistical significance.

• Human Ecology Research
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• 제53권5호
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• pp.475-488
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• 2015

Economic activity and social participation by women has recently increased; however, working mothers raising young children are under new stress due to the simultaneous combination of job and parenting responsibilities. This stress has resulted in social problems of career break and low fertility. This study investigates the effect of clinical art therapy on occupational stress and parenting stress of working mothers. We analyzed 34 working mothers in full-time employment (over 8 hours a day) who have preschool children (0-6 years old). They were divided into 17 subjects in the experimental group and 17 subjects in the control group. For the experimental group, 10 hours and a half sessions of group art therapy were participated in once a week from April to August in 2014. We perform Dan Occupational Stress Index by Ivancevich and Matteson, Parenting Stress Index/Short Form and salivary cortisol test before and after the group art therapy. For qualitative analysis, Kinetic House-Tree-Person (KHTP) drawing test was used. Using SPSS ver. 19.0, paired t -test or Wilcoxon signed rank test compared the pre and post analysis results. The results of this study are as follows. First, scores of 'occupational stress factor' subpart showed significant improvement in the Occupational Stress Index after the clinical art therapy. Second, scores of 'parental distress,' 'parent-child dysfunctional interaction,' and 'difficult child' subpart in Parenting Stress Index also showed a significant improvement. Third, a positive change was observed after the clinical art therapy in the KHTP drawing test. In conclusion, this study suggests that the clinical art therapy can be effective for occupational stress factors and the parenting stress of working mothers.

• Spatial Information Research
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• 제20권3호
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• pp.57-66
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• 2012

강원도의 경우 대부분 산지로 이루어져 있어 산사태로 인한 피해가 매우 크다. 이러한 산사태를 예방하기 위해서는 산사태 발생에 영향을 미치는 기초적인 관련 인자를 분석하는 것이 중요하다. 본 연구에서는 강원도 인제군 인제읍 덕산리 지역을 대상으로 재해 직후 촬영된 항공사진을 이용하여 육안판독에 의한 디지타이징 방법으로 산사태 발생 및 미발생 지점을 추출하였으며, GIS를 이용한 지형도, 임상도, 토양도의 중첩분석을 통하여 산사태 관련 인자에 대하여 지형학적, 임상학적, 토양학적 특성을 수량화 2종법을 이용하여 분석하였다. 분석결과 경사도는 $20^{\circ}{\sim}35^{\circ}$ 사이에서 산사태가 많이 발생하였으며, 임상 인자의 경우 침엽수가 산사태 발생 빈도와 더 큰 연관성을 보였다. 토양 인자의 경우 유효 토심이 얕을수록, 토양모재가 산성암일수록 산사태 발생빈도가 높게 나타났다.

• 대한지역사회영양학회지
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• 제8권5호
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• pp.642-651
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• 2003

This study was performed using mealtime atmosphere to characterize the food ecology of Korean children residing in different regions of Korea. A total of 705 elementary school students, 347 girls and 358 boys, were divided into three groups according to the areas where they lived, which included Seoul (n=230), provincial cities (n=273) and rural areas (n=202). The subjects were asked to fill out questionnaires which were categorized to determine various factors related to food ecology, life styles, and health related symptoms. The average age of the study subjects was 11.5 years. The results showed that the average height (p<0.01), weight (p<0.01) and body mass index (BMIs) (p< 0.01) of the rural group were significantly lower than those of the Seoul and provincial city groups. A significantly higher proportion (10.4%) of the rural group was from disfunctional families, including single parent families, than those of the Seoul (1.7%) or provincial city (4.4%) groups. However, a larger number of children from Seoul ate alone, did not enjoy their meals, and hardly talked to each other during breakfast time, compared to those from the provincial city or rural areas. Also, the proportion (33.0%) of ‘good’ in balance of meal was the lowest (33.0%) in Seoul of the three areas (p<0.01). Most of the children answered that they liked having breakfast and dinner with the whole family. In conclusion, the food ecology of elementary children differed according to the regions in which they resided. Although children from Seoul had higher BMIs, their nutritional intake was not satisfactory, and their undesirable food ecology could be a contributing factor.