• Fisheries and Aquatic Sciences
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• v.22 no.12
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• pp.30.1-30.11
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• 2019

Marine natural products isolated from the sponge Fascaplysinopsis cf reticulata, in French Polynesia, were investigated as an alternative to antibiotics to control pathogens in aquaculture. The overuse of antibiotics in aquaculture is largely considered to be an environmental pollution, because it supports the transfer of antibiotic resistance genes within the aquatic environment. One environmentally friendly alternative to antibiotics is the use of quorum sensing inhibitors (QSIs). Quorum sensing (QS) is a regulatory mechanism in bacteria which control virulence factors through the secretion of autoinducers (AIs), such as acyl-homoserine lactone (AHL) in gram-negative bacteria. Vibrio harveyi QS is controlled through three parallel pathways: HAI-1, AI-2, and CAI-1. Bioassay-guided purification of F. cf reticulata extract was conducted on two bacterial species, i.e., Tenacibaculum maritimum and V. harveyi for antibiotic and QS inhibition bioactivities. Toxicity bioassay of fractions was also evaluated on the freshwater fish Poecilia reticulata and the marine fish Acanthurus triostegus. Cyclohexanic and dichloromethane fractions of F. cf reticulata exhibited QS inhibition on V. harveyi and antibiotic bioactivities on V. harveyi and T. maritimum, respectively. Palauolide (1) and fascaplysin (2) were purified as major molecules from the cyclohexanic and dichloromethane fractions, respectively. Palauolide inhibited QS of V. harveyi through HAI-1 QS pathway at 50 ㎍ ml^-1 (26 μM), while fascaplysin affected the bacterial growth of V. harveyi (50 ㎍ ml^-1) and T. maritimum (0.25 ㎍). The toxicity of fascaplysin-enriched fraction (FEF) was evaluated and exhibited a toxic effect against fish at 50 ㎍ ml^-1. This study demonstrated for the first time the QSI potential of palauolide (1). Future research may assess the toxicity of both the cyclohexanic fraction of the sponge and palauolide (1) on fish, to confirm their potential as alternative to antibiotics in fish farming.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.2
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• pp.422-428
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• 2018

This study was conducted to investigate the effects of trunk stability exercise on knee function, balance and gait in patients who underwent total knee arthroplasty. The subjects of this study were recruited from individuals diagnosed with degenerative arthritis who had undergone total knee arthroplasty. Overall, 24 patients were randomly divided into a control groups and an experimental groups (12 each). The trunk stability exercise was conducted for 4 weeks with three exercises developed in a previous study. The measurement tools used were knee function measurements based on the Lysholm knee score, balance ability measured using a test of TUG and OLS, and a walking ability test measured using a 10MWT. Pre and post test results were within groups were compared using the paired t-test, whole differences between groups were compared using the independent t-test. The experimental group showed significantly enhanced results relative to the control group (p<0.05). Based on these results, trunk stability exercise in parallel with knee joint therapy effectively improves the recovery of patients with total knee arthroplasty.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.2
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• pp.469-475
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• 2010

The railway signalling system plays an essential role in the safe and efficient train operation as serving control functions of train operation intervals and train routes. The reliability and safety of the system are very important because the failure of the railway signalling system can lead to train collision or derailment as well as train operation stop. Until now, in railway signalling system the conventional wayside signal mode has been used generally. There are, however, the risk of accidents such as human mistakes caused by that the driver identifies the signal lamp status and controls train speed with the naked eye. It is also necessary to refurbish the obsolete system. Thereby, It is being effective that the onboard signal mode has been recently introduced and applied in order to transmit the speed control information to train by using the computer and communication equipment. It is necessary to switch over the system in a way while providing passengers with an operation service to replace the obsolete signal system. In this paper, we verify the cases through trial assessment which are solved by the way of adding specific functionalities in the problems of interference among the procedure of switch-over processes and a serial of processes for system verification while a train is operated in the new system in parallel to the existing system.

• Journal of Conservation Science
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• v.31 no.4
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• pp.387-393
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• 2015

Damages of wooden cultural heritages caused by various bio-species have been a trend that is increasing on climate change. The decay and bio-damage caused by microbial organisms or insect species are also known to factors of the shape changes and structural problems of wooden cultural heritages. There are so many phenomenons of damage and weathering in wooden cultural heritage for many years and particularly termite can threaten seriously wooden cultural heritage. We investigated with respect to internal and external environment and termite inhabitation around the wooden cultural heritage in Jeollanam-do, Jeollabuk-do, and Jeju-do. As this investigation results, we confirmed that there were the difference in between resident and non-resident about temperature, humidity, moisture contents of wooden building. Resident building is high temperature but humidity and moisture contents is low and these factors are sources of inhabitation condition change about insects as termites. Now we suggest to carry out in parallel to the target wooden cultural heritage and the surrounding habitat for wooden cultural heritage termite damage investigation. Also with the chemical control methods, we must consider necessary to present eco-friendly control management such as construction of heating facilities, residential status, periodic management.

• Current Research on Agriculture and Life Sciences
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• v.8
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• pp.1-8
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• 1990

The experiment was conducted to study on the germination of seeds, and chemical change in the endorsperm and embryo of maize seeds treated with gibbrellic acid(GA) 25, G A 50, bengyl adenine(BA) 100 and B A 200 ppm. Obtained results can be summerized as follows: 1. The germination rate in the initial stage of maize seed increased most with G A 25 ppm treated but decreased most with B A 200 ppm treatment amount other treated blocks. There is no significant difference between treatments in the middle and later stage of the seed germination. 2. The quantity of Q $CO_2$ was noticeably increased together in parallel with germination at each blocks, but such fact was found that the block of treatment has low Q $CO_2$ in comparison with control and in particular, has the tendency to take very low in B A 200 ppm. 3. The amount of reducing sugar and total sugars among embryo and endosperm are promptly increased at each blocks, but B A treatment shows low rate of increase in comparison with the non treatment and G A treatment. 4. The quantity of crude protein of seed during germination are increased at the part of embryo and decreased at the part of endosperm. Such degree is most prominent in the treatment with G A 25 ppm and changing degree of treatment with 200 ppm is lowest.

• The Journal of the Korea Contents Association
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• v.9 no.11
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• pp.271-279
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• 2009

Frozen shoulder is clinically characterized by pain and reduced ROM. The therapeutic goal of frozen shoulder can be reducing pain and increasing ROM in shoulder joint, resulting in improvement of joint movement. Therefore, this study was conducted to know the effect of mobilization in parallel with conservative physical therapy(H/P, TENS, U/S) in patients with frozen shoulder on subjective pain scale and ROM. 26 patients diagnosed with frozen shoulder were included for study. Among them, 13 patients(experiment group) were managed by mobilization as well as conservative physical therapy, another 13 patients(control group) were only treated by conservative physical therapy alone. All the patients were treated three times a week for 4 weeks, and after each treatment subjective pain scale and ROM were measured. In experimental group, pain has decreased and ROM has increased in abduction, external rotation and internal rotation. In control group, pain has also decreased but ROM has not changed in abduction, external rotation and internal rotation. There were no significant difference in subjective pain scale between two groups but some difference in ROM (external rotation, internal rotation). According to the results, we concluded that both conservative physical therapy and joint mobilization technique are more effective for increasing ROM especially external rotation, internal rotation than conservative physical therapy alone.

• Tunnel and Underground Space
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• v.13 no.6
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• pp.486-494
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• 2003

When the orientations of joints are measured on a rock exposure, there are frequent cases that are difficult to approach by the surveyor to the target joints or to set up scanlines on the slope. In this study, to complement such limit and weak points, a new algorithm was developed to interpret joint orientation from analyzing the images of rock slope. As a method of arranging the multiple images of a rock slope, the multistage convergent photographing system was introduced to overcome the limitation of photographing direction which existing method such as parallel stereophotogrammetric system has and to cover the range of image measurement, which is the overlapping area between the image pair, to a maximum extent. To determine camera parameters in the perspective projection equation that are the main elements of the analysis method, a new method was developed introducing three ground control points and single ground guide point. This method could be considered to be very simple compared with other existing methods using a number of ground control points and complicated analysis process. So the global coordinates of a specific point on a rock slope could be analyzed with this new method. The orientation of a joint could be calculated using the normal vector of the joint surface which can be derived from the global coordinates of several points on the joint surface analyzed from the images.

• The Journal of Korean Academy of Prosthodontics
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• v.38 no.2
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• pp.200-213
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• 2000

Lasers have given dentistry a new rapid, economic, and accurate technique for metal joining. Although laser welding has been recommended as an accurate technique, there are some limitations with this technique. For example, the two joining surfaces must have a tight-fitting contact, which may be difficult to achieve in some situations. The tensile samples used for this study were made from a custom-made pure titanium and type III gold alloy plates. 27 of 33 specimens were sectioned perpendicular to their long axis with a carborundum disk and water coolant. Six specimens remained and served as the control group. A group of 6 specimens was posed as butt joints in custom parallel positioning device with a feeler gauge at each of three gaps : 0.00, 0.25. and 0.50mm. All specimens were then machined to produce a uniform cross-sectional dimension, none of the specimens was subjected to any subsequent form of heat treatment. Scanning electron microscopy was performed on representative tested specimens at fractured surfaces in both the parent metal and the weld. Vickers hardness was measured at the center of the welds with a micropenetrometer using a force of 300gm for 15 seconds. Measurement was made at approximately $200{\mu}m\;and\;500{\mu}m$ deep from each surface. One-way analysis of variance (ANOVA) and Scheffe's test was calculated to detect differences between groups. The purpose of this study is to compare the strength and properties of the joint achieved at various butt Joint gaps by the laser welding of type III gold alloy and pure titanium tensile specimens in an argon atmosphere. The results of this study were as follows : 1. When indexing and welding pure titanium, there was no decrease in ultimate tensile strength as compared with the unsectioned alloys for indexing gaps of 0.00 to 0.50mm, although with increasing gap size may come increased distortion (p>0.05). 2. When indexing and welding type III gold alloy, there were significant differences in ultimate tensile strength among groups with weld gaps of 0.00mm, 0.25 and 0.50mm, and the control group. Group with butt contact without weld gap demonstrated a significant higher ultimate tensile strength than groups with weld gaps of 0.25 and 0.50mm (p<0.05). 3. When indexing and welding the different metal combination of type III gold alloy and pure titanium, there were significant differences in ultimate tensile strength between groups with weld gaps of 0.00, 0.25, and 0.50mm. However, the mechanical properties of the welded joint would become too brittle to be acceptable clinically (p<0.05). 4. The presence of large pores in the laser welded joint appears to be the most important factor in controlling the tensile strength of the weld in both pure titanium and type III gold alloy.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.4 no.4
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• pp.43-61
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• 1981

Interest in the Quality of working life is spreading rapidly and the phrase has entered the popular vocabulary. That this should be so is probably due in large measure to changes in the values of society, nowadays accelerated as never before by the concerns and demands of younger people. But however topical the concept has become, there is very little agreement on its definition. Rather, the term appears to have become a kind of depository for a variety of sometimes contradictory meanings attributed to it by different groups. A list of all the elements it if held to cover would include availability and security of employment, adaquate income, safe and pleasant physical working conditions, reasonable hours of work, equitable treatment and democracy in the workplace, the possibility of self-development, control over one's work, a sense of pride in craftsmanship or product, wider career choices, and flexibility in matters such as the time of starting work, the number of working days in the week, Job sharing and so on altogether an array that encompasses a variety of traditional aspirations and many new ones reflecting the entry into the post industrial era. The term "quality of working life" was introduced by professor Louis E. Davis and his colleagues in the late 1960s to call attention to the prevailing and needlessly poor quality of life at the workplace. In their usage it referred to the quality of the relationship between the worker and his working environment as a whole, and was intended to emphasize the human dimension so often forgotten among the technical and economic factors in job design. Treating workers as if they were elements or cogs in the production process is not only an affront to the dignity of human life, but is also a serious underestimation of the human capabilities needed to operate more advanced technologies. When tasks demand high levels of vigilence, technical problem-solving skills, self initiated behavior, and social and communication skills. it is imperative that our concepts of man be of requisite complexity. Our aim is not just to protect the worker's life and health but to give them an informal interest in their job and opportunity to express their views and exercise control over everything that affects their working life. Certainly, so far as his work is concerned, a man must feel better protected but he must also have a greater feeling of freedom and responsibility. Something parallel but wholly different if happening in Europe, industrial democracy. What has happened in Europe has been discrete, fixed, finalized, and legalized. Those developing centuries driving toward industrialization like R.O.K, shall have to bear in mind the human complexity in processing and designing the work and its environment. Increasing attention is needed to the contradiction between autocratic rule at the workplace and democratic rights in society.n society.

• Journal of the Korean Wood Science and Technology
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• v.43 no.6
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• pp.868-875
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• 2015

In order to replace existing slit type steel plate on the wooden structure joint, the FRP-reinforced laminated plates were produced. Four types of FRP-reinforced laminated plates were produced according to the type of reinforcement and adhesive, and before applying to the joint, the adhesion performance test according to KSF 3021 and KSF 2160 and the Compact Tension (CT) type fracture toughness test specified in ASTM D5045-99 were carried out. As a result of adhesion performance test, all GFRP textile, GFRP sheet, and GFRP Textile-Sheet type FRP-reinforced laminated plates satisfied the requirement of soaking delamination percentage with smaller than 5% based on KS standard. However, aramid type specimen satisfied the standard as the soaking delamination percentage of 4.8% but it did not satisfied the standard as the water proof soaking delamination percentage of 70%. As a result of fracture toughness test, the volume ratio of reinforcement to timber became 23% so that the strength of FRP-reinforced laminated plates increased by two to four times in comparison to the control specimen. It was confirmed that the GFRP Textile-Sheet type specimen was most resistant to the fracture most since the ratio of stress intensity factor compared with that of the control increased to 61% owing to the parallel arrangement of glass fiber to the load. As a result of tensile shear strength test using FRP-reinforced laminated plates and nonmetal dowels, it is about 12% lower than metal connectors.