• Title/Summary/Keyword: Paper-based analytical devices

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Recent Advances in a Microfluidic Paper-based Analytical Devices and its Point of Care Testing Applications (종이기반 미세유체 분석소자를 활용한 현장검사 기술과 그 응용)

  • Yoo, Yong Kyoung;Kim, Cheonjung;Lee, Junwoo;Lee, Jeong Hoon
    • Ceramist
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    • v.21 no.3
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    • pp.293-301
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    • 2018
  • Paper-based analytical devices (${\mu}PAD$) are highly advantageous for portable diagnostic systems owing to their low costs and ease of use. ${\mu}PADs$ are considered as the best candidates for realizing the World Health Organization (WHO) ASSURED criteria: affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and deliverable to end users. However, they have several limitations such as low sensitivity and accuracy. This article reports a mini review for a micro-fluidic paper-based analytical devices (${\mu}PAD$), especially for addressing low sensitivity and accuracy issues.

Direct Detection of Water-dissolved Ammonia Using Paper-based Analytical Devices

  • Yeong Beom Cho;Duc Cuong Nguyen;Si Hiep Hua;Yong Shin Kim
    • Journal of Sensor Science and Technology
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    • v.32 no.2
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    • pp.67-74
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    • 2023
  • A microfluidic paper-based analytical device (µPAD) is proposed for the selective detection of ammonia in water by using the modified Berthelot reagent and a fluidic channel consisting of hollow paper. The modified Berthelot reagents were uniformly dispersed in cyclohexane and then immobilized in a detection zone of the µPAD. The loading position of the reagents and the type of a sample flow channel were optimized to achieve a sensitive ammonia detection within a short analytical time. The NH3 µPAD exhibits a linear colorimetric response to the concentration of ammonia dissolved in water in the range of 1-100 mg L-1, and its limit-of-detection is 1.75 mg L-1. In addition, the colorimetric response was not influenced by the addition of 100 mg L-1 nitrogen containing compounds (sodium nitrate, sodium nitrite, uric acid, hydroxylamine, butylamine, diethylamine) or inorganic salts (NaCl, Na2HPO4), presenting the enough selectivity in the detection of water-dissolved ammonia against possible interferents.

Angular-based Measurement for Quantitative assay of Albumin in three-dimensional Paper-based analytical Device (회전각도를 이용한 알부민 농도 측정용 3차원 종이 칩)

  • Kim, Dong-Ho;Jeong, Seong-Geun;Lee, Chang-Soo
    • Korean Chemical Engineering Research
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    • v.58 no.2
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    • pp.286-292
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    • 2020
  • This study presents an angular-based measurement on three-dimensional paper-based analytical devices (3D-PADs) for quantitative detection of albumin without using an image analyzer. We demonstrate a simple quantitative and straightforward approach based on the angle of the discolored area as detection criteria. 3D-PADs are rapidly fabricated by the wax-printing and laminating process. The 3D-PADs are treated with citrate buffer and tetrabromophenol blue to react with albumin in a sample solution. Dropping sample solution into sample pad in the 3D-PAD, fluid flows toward the assay zone laterally and vertically by capillary action. We find that the change of angle of the discolored area correctly reflects the concentration of albumin and is reliable determinant for the measurement of the albumin concentration. It is the first demonstration of angular-based detection as a simple, inexpensive, and equipment-free approach for point-of-care diagnosis.

Paper-Based Bipolar Electrochemistry

  • Renault, Christophe;Scida, Karen;Knust, Kyle N.;Fosdick, Stephen E.;Crooks, Richard M.
    • Journal of Electrochemical Science and Technology
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    • v.4 no.4
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    • pp.146-152
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    • 2013
  • We demonstrate that carbon electrodes screen-printed directly on cellulose paper can be employed to perform bipolar electrochemistry. In addition, an array of 18 screen-printed bipolar electrodes (BPEs) can be simultaneously controlled using a single pair of driving electrodes. The electrochemical state of the BPEs is read-out using electrogenerated chemiluminescence. These results are important because they demonstrate the feasibility of coupling bipolar electrochemistry to microfluidic paperbased analytical devices (${\mu}PADs$) to perform highly multiplexed, low-cost measurements.

A Time-Constrained Information Processing Model in Ubiquitous Environments

  • Hur, Sun;Lee, Hyun;Shin, Dong-Min;Lee, Won-Suk
    • ETRI Journal
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    • v.29 no.4
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    • pp.489-496
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    • 2007
  • As pervasive computing is widely adopted and reliable networks are becoming more easily accessible, there is a rapidly growing need to develop a mechanism to analyze and evaluate the performance of ubiquitous environments. This paper presents an information processing model which characterizes a ubiquitous environment where a variety of pieces of information need to be exchanged among devices within a system. The proposed model not only provides analytical tools to evaluate the performance of devices, but also makes it possible to identify key factors in designing a ubiquitous environment. For illustrative purposes, a test bed is constructed and the performance of the system is assessed based on the proposed model.

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고출력 GaN-based LED의 열적 설계 및 패키징

  • 신무환
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2003.11a
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    • pp.24-24
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    • 2003
  • Research activity in the III-V nitrides materials system has increased markedly in the past several years ever since high-brightness blue light-emitting diodes (LEDs) became commercially available. Despite of excellent optical properties of the GaN, however, inherently poor thermal property of the sapphire used as a substrate material n these devices may lead to thermal degradation of devices, especially during their high power operation. Therefore, dependable thermal analysis and packaging schemes of GaN-based LEDs are necessary for solid lighting applications under high power operation. In this paper, emphasis will be placed upon thermal design of GaN-based LEDs. Thermal measurements of LEDs on chip and packaging scale were performed using the liquid crystal thermographic technology and micro thermocouples for different bias conditions. By a series of optical arrangement, hot spots with specific transition temperatures were obtained with increasing input power. Thermal design of LEDS was made using the finite element method and analytical unit temperature profile approach with optimal boundary conditions. The experimental results were compared to the simulated data and the results agree well enough for the establishment of dependable prediction of thermal behavior in these devices. The paper will present a more detailed understanding of the thermal analysis of the GaN-based blue and white LEDs for high power applications.

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Vibration control of mechanical systems using semi-active MR-damper

  • Maiti, Dipak K.;Shyju, P.P.;Vijayaraju, K.
    • Smart Structures and Systems
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    • v.2 no.1
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    • pp.61-80
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    • 2006
  • The concept of structural vibration control is to absorb vibration energy of the structure by introducing auxiliary devices. Various types of structural vibration control theories and devices have been recently developed and introduced into mechanical systems. One of such devices is damper employing controllable fluids such as ElectroRheological (ER) or MagnetoRheological (MR) fluids. MagnetoRheological (MR) materials are suspensions of fine magnetizable ferromagnetic particles in a non-magnetic medium exhibiting controllable rheological behaviour in the presence of an applied magnetic field. This paper presents the modelling of an MRfluid damper. The damper model is developed based on Newtonian shear flow and Bingham plastic shear flow models. The geometric parameters are varied to get the optimised damper characteristics. The numerical analysis is carried out to estimate the damping coefficient and damping force. The analytical results are compared with the experimental results. The results confirm that MR damper is one of the most promising new semi-active devices for structural vibration control.

High-Frequency GaN HEMTs Based Point-of-Load Synchronous Buck Converter with Zero-Voltage Switching

  • Lee, Woongkul;Han, Di;Morris, Casey T.;Sarlioglu, Bulent
    • Journal of Power Electronics
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    • v.17 no.3
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    • pp.601-609
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    • 2017
  • Gallium nitride (GaN) power switching devices are promising candidates for high switching frequency and high efficiency power conversion due to their fast switching, low on-state resistance, and high-temperature operation capability. In order to facilitate the use of these new devices better, it is required to investigate the device characteristics and performance in detail preferably by comparing with various conventional silicon (Si) devices. This paper presents a comprehensive study of GaN high electron mobility transistor (HEMT) based non-isolated point-of-load (POL) synchronous buck converter operating at 2.7 MHz with a high step-down ratio (24 V to 3.3 V). The characteristics and performance of GaN HEMT and three different Si devices are analytically investigated and the optimal operating point for GaN HEMT is discussed. Zero-voltage switching (ZVS) is implemented to minimize switching loss in high switching frequency operation. The prototype circuit and experimental data support the validity of analytical and simulation results.

User Adaptive Restaurant Recommendation Service in Mobile Environment based on Bayesian Network Learning (베이지안 네트워크의 학습에 기반한 모바일 환경에서의 사용자 적응형 음식점 추천 서비스)

  • Kim, Hee-Taek;Cho, Sung-Bae
    • 한국HCI학회:학술대회논문집
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    • 2009.02a
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    • pp.6-10
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    • 2009
  • In these days, recommendation service in mobile environments is in the limelight due to the spread of mobile devices and an increase of information owing to advancement of computer network. The restaurant recommendation system reflecting user preference was proposed. This system uses Bayesian network to model user preference and analytical hierarchical process to recommend restaurants, but static inference model for user preference used in the system has some limitations that cannot manage changing user preference and enormous user survey must be preceded. This paper proposes a learning method for Bayesian network based on user requests. The proposed method is implemented on mobile devices and desktop, and we show the possibility of the proposed method through experiments.

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Analysis of Doping Profile Dependent Threshold Voltage for DGMOSFET Using Gaussian Function

  • Jung, Hak-Kee
    • Journal of information and communication convergence engineering
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    • v.9 no.3
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    • pp.310-314
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    • 2011
  • This paper has presented doping profile dependent threshold voltage for DGMOSFET using analytical transport model based on Gaussian function. Two dimensional analytical transport model has been derived from Poisson's equation for symmetrical Double Gate MOSFETs(DGMOSFETs). Threshold voltage roll-off is very important short channel effects(SCEs) for nano structures since it determines turn on/off of MOSFETs. Threshold voltage has to be constant with decrease of channel length, but it shows roll-off due to SCEs. This analytical transport model is used to obtain the dependence of threshold voltage on channel doping profile for DGMOSFET profiles. Also we have analyzed threshold voltage for structure of channel such as channel length and gate oxide thickness.