• 제목/요약/키워드: Papaveraceae

검색결과 28건 처리시간 0.032초

한국산 양귀비과 식물에 관한 본초학적 연구 (A Herbological Study on the Plants of Papaveraceae in Korea)

  • 정종길
    • 대한본초학회지
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    • 제31권5호
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    • pp.63-69
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    • 2016
  • Objective : For the purpose of developing Korean herbology of the plants to Papaveraceae in Korea, the literatures of the successive generations have been thoroughly investigated to prepare this article.Methods : Books and research papers about Herbology which published at home and abroad were examined.Results : A list was made about Papaveraceae plant which were cultivated or grew naturally in Korea, after investigated the data on domestic and foreign Papaveraceae plants. Out of those lists, serviceable plants were selected and with those available plants, their distributions were analysed and parts which can be used as medicines were divided into 3 categories such as oriental medicine name, scientific name and non-official name. Papaveraceae's properties flavor, channels they use, effects, and toxicity were also noted. Papaveraceae (grew in Korea) were divided into 4 classes with 8 species. Out of those, 3 classes with 4 species were found serviceable which indicates 50% of all. Out of all 8 species of Papaveraceae family, Papaver genus were found 4 species, which were shown the most. Among 3 genus of 4 species, medicinal plants were all one species each. Out of all serviceable parts in Papaveraceae, Radix and Herba, Etc parts took first place as 2 species. There are toxic, the 3 species and 6 parts survey said.Conclusion : There were totaled to 4 genera and 8 species in Papaveraceae in Korea and among them medicinal plants are 3 genera, 4 species, some 50% in total.

Inhibitory Effect of Corynoline Isolated from the Aerial Parts of Corydalis incisa on the Acetylcholinesterase

  • Kim, Dae-Keun
    • Archives of Pharmacal Research
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    • 제25권6호
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    • pp.817-819
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    • 2002
  • In the course of screening Korean natural products for acetylcholinesterase (AChE) inhibitory activity, it was found that a methanolic extract of the aerial parts of Corydalis incisa (Papaveraceae) showed significant inhibitory effects on AChE. Corynoline isolated from this plant inhibited AChE activity in a dose-dependent manner, and the $IC_{50}$ value of corynoline was $30.6{\;}{\mu}M$. The AChE inhibitory activity of corynoline was reversible and noncompetitive.

눈괴불주머니 지상부의 Isoquinoline alkaloid성분 (Isoquinoline Alkaloids from the Aerial Parts of Corydalis ochotensis)

  • 이기택;엄상섭;은재순;신태용;임종필
    • 약학회지
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    • 제45권5호
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    • pp.442-447
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    • 2001
  • Aerial parts of Corydalis ochotensis Turcz. (Papaveraceae) has been used as a folk medicine in China for its antipyretic, analgesic and diuretic properties, which is widely distributed in Korea. Phytochemical study of the aerial parts of C. ochotensis led to the isolation of three isoquinoline alkaloids, (+)adlumidine, govadine and (-)severtzine, together with quercetin, rutin and tridecanoic acid. These compounds were established by conventional methods of analysis and identified by $^{1}$H,$^{13}$ C-NMR, and MS data.

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Phylogenetic relationships of Coreanomecon (Papaveraceae: Papaveroideae), an endemic genus in Korea, using DNA sequences

  • YUN, Narae;OH, Sang-Hun
    • 식물분류학회지
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    • 제48권4호
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    • pp.289-300
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    • 2018
  • Coreanomecon is a monotypic and endemic genus in Korea, distributed mainly in the southern regions. Coreanomecon is morphologically similar to Hylomecon by producing red latex, easily distinguished from Chelidonium, which produces yellow latex. Coreanomecon were merged into Hylomecon or Chelidonium depending on the authors. To understand the phylogenetic relationship of Coreanomecon, DNA sequences of chloroplast rbcL and matK and nuclear Internal Transcribed Spacer (ITS) regions were determined from the species of Papaveroideae (Papaveraceae) in Korea and analyzed with the Maximum Parsimony and Bayesian methods. Phylogenetic analyses of Papaveroideae suggest that Coreanomecon is sister to the clade of Chelidonium and Stylophorum in the ITS data and that it is sister to Hylomecon in the chloroplast (cpDNA) data. A constraining analysis using the Shimodaira-Hasegawa test (S-H test) suggested that the ITS data do not reject the sister relationship of Coreanomecon and Hylomecon. The S-H test also suggested that the cpDNA data is compatible with the placement of Coreanomecon as a sister to the clade of Chelidonium and Stylophorum. Although the conflicting phylogenetic results may stem from insufficient phylogenetic signals, they may also be associated with hybridization between Hylomecon and an ancestor of Stylophorum and Chelidonium. The results of this study suggest that Coreanomecon is a distinct lineage as an endemic genus, supporting the morphological data.

현호색의 품질 표준화 연구 (Determination of Dehydrocorydaline in the Corydalis Tuber Using HPLC-UVD)

  • 김정아;최지영;김동춘;이희상;이승호
    • 생약학회지
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    • 제39권4호
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    • pp.305-309
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    • 2008
  • Dehydrocorydaline was isolated from the roots of Corydalis ternata (Papaveraceae) and identified by the comparison the $^1H-$ and $^{13}C$-NMR spectral data with those of authentic sample. The content of dehydrocorydaline was determined by the HPLC analysis based on extraction of ground plant material. Quantitative analysis of dehydrocorydaline in MeOH extract of C. ternata by HPLC showed $1.31{\pm}0.95%$ in 20 samples collected throughout regions of Korea.

The First Step of Biotechnological Approaches for Alkaloid Biosynthesis in Papaveraceae: In vitro Plant Regenerations

  • Park, Sang-Un;Yu, Chang-Yeon;Chae, Young-Am
    • 한국약용작물학회지
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    • 제12권5호
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    • pp.428-435
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    • 2004
  • Alkaloid producing species of plants have long been a major component of the medicinal social and magico-religious aspects of human culture. A diverse array of biological activities has been attributed to different alkaloids including numerous members of benzylisoquinoline family of alkaloids. For biotechnological approaches of alkaloid biosynthesis in poppy family, plant regeneration protocol through somatic embryogenesis or shoot organogenesis is a first step. This paper describes the methods and applications of plant regeneration of poppy family.

들현호색으로부터 Berberine과 Coptisine의 분리 및 함량분석 (Isolation and Quantitative Determination of Berberine and Coptisine from Tubers of Corydalis ternata)

  • 이향이;김종원
    • 생약학회지
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    • 제30권3호
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    • pp.332-334
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    • 1999
  • Corydalis Tuber has been used in traditional medicine for an analgesic, antispasmodic and gastric ulcers. For the quality control on this drug, isolation and quantitative determination of berberine and coptisine from Corydalis ternata Nakai (Papaveraceae) has been conducted by using HPLC method. Berberine and coptisine in quarternary alkaloidal fraction from the crude drug were separated on silicagel column using a $CHCl_3:MeOH\;(85:15)$ and $CHCl_3:MeOH:H_2O\;(70:30:4)$ as an eluent, and the average contents were about 0.93 and 0.36%.

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Cytotoxic Constituents from the Whole Plant of Corydalis pallida

  • Kim Hyang Rim;Min Hye-Young;Jeong Yeon Hee;Lee Sang Kook;Lee Nam Sook;Seo Eun-Kyoung
    • Archives of Pharmacal Research
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    • 제28권11호
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    • pp.1224-1227
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    • 2005
  • Here we report the cytotoxic activity of three known compounds isolated for the first time from Corydalis pallida (Papaveraceae). An isoquinoline alkaloid, berberine, exhibited cytototoxic activity against two human cancer cell lines, HT-1080 (human fibrosarcoma) and SNU-638 (human stomach adenocarcinoma), with $IC_{50}$ values of 3.2 and 3.4 $\mu$g/mL, respectively. N­trans-feruloyltyramine and N-trans-feruloylmethoxytyramine were also isolated from this plant but were inactive.