• The Korean Journal of Nuclear Medicine
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• v.32 no.1
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• pp.32-49
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• 1998

For estimation of regional myocardial blood flow with O-15 water PET, a few modifications considering partial volume effect based on single compartment model have been proposed. In this study, we attempted to quantify the degree of heterogeneity and to show the effect of tissue flow heterogeneity on partition coefficient(${\lambda}$) and to find the relation between perfusable tissue index(PTI) and ${\lambda}$ by computer simulation using two modified models. We simulated tissue curves for the regions with homogeneous and heterogeneous blood flow over a various flow range(0.2-4.0ml/g/min). Simulated heterogeneous tissue composed of 4 subregions of the same or different size of block which have different homogeneous flow and different degree of slope of distribution of blood flow. We measured the index representing heterogeneity of distribution of blood flow for each heterogeneous tissue by the constitution heterogeneity(CH). For model I, we assumed that tissue recovery coefficient ($F_{MME}$) was the product of partial volume effect($F_{MMF}$) and PTI. Using model I, PTI, flow, and $F_{MM}$ were estimated. For model II, we assumed that partition coefficient was another variable which could represent tissue characteristics of heterogeneity of flow distribution. Using model II, PTI, flow and ${\lambda}$ were estimated. For the simulated tissue with homogeneous flow, both models gave exactly the same estimates, of three parameters. For the simulated tissue with heterogeneous flow distribution, in model I, flow and $F_{MM}$ were correctly estimated as CH was increased moderately. In model II, flow and ${\lambda}$ were decreased curvi-linearly as CH was increased. The degree of underestimation of ${\lambda}$ obtained using model II, was correlated with CH. The degree of underestimation of flow was dependent on the degree of underestimation of ${\lambda}$. PTI was somewhat overestimated and did not change according to CH. We conclude that estimated ${\lambda}$ reflect the degree of tissue heterogeneity of flow distribution. We could use the degree of underestimation of ${\lambda}$ to find the characteristic heterogeneity of tissue flow and use ${\lambda}$ to recover the underestimated flow.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.6
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• pp.894-901
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• 2012

The effect of Sopung-tang(SPT) and trans-cranial direct current stimulation(tDCS) was investigated in photothrombotic brain infarction(PTI) rats. Sprague-Dawley 80 rats, were divided into four groups. group I was experiental control group(n=20), group II was PTI induced and oral administration of SPT(n=20), group III was PTI induced and tDCS administration(n=20) and group IV was PTI induced and SPT and tDCS administration for 28 days on stroke rats(n=20). Analysis the neurological function test, 25 point behavior functional score test, and immunohistochemistric finding of GDNF expression, and electron microscopy assessment In motor behavior test, the outcome of group IV was significantly difference than the other group, and In immunohistochemistric finding, group II, III, IV were increase GDNF expression on 28 days, In electron microscopy finding, the all groups were degenerated of cell organelles, and synaptic plasticity were improvement of group II, III, IV(especially group IV) These results suggest that, 28days application of SPT and tDCS was the motor function and histopathologic, micro-morphological improvement of motor function recovery and positive influence on synaptic plasticity.

• Molecules and Cells
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• v.42 no.7
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• pp.503-511
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• 2019

As sessile organisms, plants have developed sophisticated system to defend themselves against microbial attack. Since plants do not have specialized immune cells, all plant cells appear to have the innate ability to recognize pathogens and turn on an appropriate defense response. The plant innate immune system has two major branches: PAMPs (pathogen associated molecular patterns)-triggered immunity (PTI) and effector-triggered immunity (ETI). The ability to discriminate between self and non-self is a fundamental feature of living organisms, and it is a prerequisite for the activation of plant defenses specific to microbial infection. Arabidopsis cells express receptors that detect extracellular molecules or structures of the microbes, which are called collectively PAMPs and activate PTI. However, nucleotidebinding site leucine-rich repeats (NB-LRR) proteins mediated ETI is induced by direct or indirect recognition of effector molecules encoded by avr genes. In Arabidopsis, plasmamembrane localized multifunctional protein RIN4 (RPM1-interacting protein 4) plays important role in both PTI and ETI. Previous studies have suggested that RIN4 functions as a negative regulator of PTI. In addition, many different bacterial effector proteins modify RIN4 to destabilize plant immunity and several NB-LRR proteins, including RPM1 (resistance to Pseudomonas syringae pv. maculicola 1), RPS2 (resistance to P. syringae 2) guard RIN4. This review summarizes the current studies that have described signaling mechanism of RIN4 function, modification of RIN4 by bacterial effectors and different interacting partner of RIN4 in defense related pathway. In addition, the emerging role of the RIN4 in plant physiology and intercellular signaling as it presents in exosomes will be discussed.

• KIEE International Transactions on Power Engineering
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• v.3A no.3
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• pp.161-167
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• 2003

This paper presents a study performed to investigate the steady-state operational strategies of UPFCs in the Jeollanam-Do system in Korea. The objective of the study was to determine the UPFC operating points under normal and contingency conditions. The study consists of developing load flow models to simulate different load levels with and without UPFCs in the system, assessing the effectiveness of UPFCs by contingency analysis, and introducing optimal corrective actions for removing voltage problems caused by contingencies. The paper describes analytical tools, models and approach. It also includes analysis and discussion of the study results. The paper contributes to the area of transmission operational studies with FACTS applications.

• Proceedings of the Korean Nuclear Society Conference
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• 1998.05b
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• pp.711-714
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• 1998

H$_2$$^{15}$ O PET을 이용하여 심근혈류를 측정할 때 물의 분포가 조직마다 불균일한 특성을 나타내고자 관류 가능한 조직분획(perfusable tissue index; PTI)$^{1)}$ 개념을 도입한 연구가 보고된 바 있으나 PTI로는 비균일성을 정량적으로 다루지 못하였다$^{2)}$ . 반면에 단일 구획 모델에서 분배계수(partition coefficient: λ)를 변수로 추정하여 혈류분포의 비 균일성을 나타낼 수 있음을 컴퓨터 모의실험으로 보인 연구가 있다$^{3)}$ . 이 연구에서는 이미 앞서 발표한 연구의 혈류측정 모델을 정상인 실험용 개에 적용하였으며 그 결과 혈류와 분배계수 모두가 정상 범위 안에 들어옴을 확인하였다. 또한 컴퓨터 모의실험을 통해 얻은 분배계수와 비균일성 지표인 구성비균일성(constitution heterogeneity; CH) 와의 관계를 이용하여 동물실험에서 측정한 분배계수로부터 CH를 유추해 보았다.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.3
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• pp.107-117
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• 2022

Purpose : The purpose of this study was to establish a model of the predictive factors for success or failure of examinees undertaking the Korean physical therapist licensing examination (KPTLE). Additionally, we assessed the pass/fail cut-off point. Methods : We analyzed the results of 10,881 examinees who undertook the KPTLE, using data provided by the Korea Health Personnel Licensing Examination Institute. The target variable was the test result (pass or fail), and the input variables were: sex, age, test subject, and total score. Frequency analysis, chi-square test, descriptive statistics, independent t-test, correlation analysis, binary logistic regression, and receiver operating characteristic (ROC) curve analyses were performed on the data. Results : Sex and age were not significant predictors of attaining a pass (p>.05). The test subjects with the highest probability of passing were, in order, medical regulation (MR) (Odds ratio (OR)=2.91, p<.001), foundations of physical therapy (FPT) (OR=2.86, p<.001), diagnosis and evaluation for physical therapy (DEPT) (OR=2.74, p<.001), physical therapy intervention (PTI) (OR=2.66, p<.001), and practical examination (PE) (OR=1.24, p<.001). The cut-off points for each subject were: FPT, 32.50; DEPT, 29.50; PTI, 44.50; MR, 14.50; and PE, 50.50. The total score (TS) was 164.50. The sensitivity, specificity, and the classification accuracy of the prediction model was 99 %, 98 %, and 99 %, respectively, indicating high accuracy. Area under the curve (AUC) values for each subject were: FPT, .958; DEPT, .968; PTI, .984; MR, .885; PE, .962; and TS, .998, indicating a high degree of fit. Conclusion : In our study, the predictive factors for passing KPTLE were identified, and the optimal cut-off point was calculated for each subject. Logistic regression was adequate to explain the predictive model. These results will provide universities and examinees with useful information for predicting their success or failure in the KPTLE.

• KIEE International Transactions on Power Engineering
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• v.3A no.3
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• pp.168-176
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• 2003

The Korea Electric Power Corporation (KEPCO) has installed an 80 MY A Unified Power Flow Controller (UPFC) at its 154㎸ 'Kang-Jin Substation in South Korea. The device, manufactured by Siemens & Hyusung, has been operational since October 2002. The Korea Electric Power Research Institute (KEPRI), a division of KEPCO was tasked to study operational strategies that could be employed for the UPFC and surrounding reactive support devices concerning problems of low voltages and overloads in the Mokpo & Gwangju areas. Particular apprehension surrounded the possibility of delay in the installation of a new 345㎸ transmission line from 2005 to beyond 2010. The studies were to specifically determine whether these problems could be eliminated by application of a UPFC. The analysis included determining the UPFC operating point under various conditions, investigations of the coordination between the UPFC and a HYDC line terminating in this area, and the design of a supplementary damping controller for the UFPC. This paper summarizes the results of those studies, demonstrating the dynamic characteristics of the operation of this UPFC operation in the Korean power system.

• Journal of the Korea institute for structural maintenance and inspection
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• v.20 no.6
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• pp.73-83
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• 2016

Bearing stress near anchor plates is usually very high due to prestressing force in anchorage zone of concrete structure used post-tensioned prestressed method. In order to effective utilization of cross section and crack control, appropriate size of anchorage plates should be used to prevent crack initiation and failure of concrete structures eventually. This study aims to suggest equation for effective area of bearing plate of rectangle type and circular type by Highway Bridge Design Specification and PTI etc. A shape factor according to bearing plate shape is suggested based on numerical analysis, and it can be used suitability for design of special anchorage plate dimension.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.04a
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• pp.361-364
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• 2008

This study was performed to estimate the anchorage behavior for Bi Prestressed Concrete Girder(Bicon girder) which could introduce effectively prestressed forces into concrete girders. A bicon girder is manufactured by means of introducing pure bending moment that prestress simultaneously the compressive member(steel bar) and the tensile member(steel tendon). Therefore, the steel bar and the steel tendon must be unified in both ends and compressive and tensile force be offset. Anchorage dimension of 6 test specimens was designed under PTI specification which defined maximum stress and deformation to estimate structural behavior. Test results showed that the stress and the deformation of anchorage were within limits if the steel bar behaviored elastically.

• 전기의세계
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• v.44 no.1
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• pp.10-18
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• 1995

송전망 확충과 병행하여 기존선로를 최대한으로 활용하는 문제가 대되되어 왔고, 동일한 송전선로 확보공간을 보다 효율적으로 사용하여 전력전송을 극대화 하기 위한 연구가 추진되어 왔다. 그 대책으로서 송전전압 격상을 추진하고 있고, 신 전력전송기술의 하나로 FACTS가 연구되고 있음과 아울러, 기존 송전시스템을 그대로 활용하면서 근본적인 전력전송을 증대시키는 방안으로 고다상 송전(High Phase Order(HPO) Transmission)에 관한 연구가 10여년전부터 미국을 중심으로 추진되어 왔으며, New York State Electric and Gas Corporation사는 최근 실계통인 115KV Goudey-Oakdale 송전선로에 6상 송전을 시험 적용하기에 이르렀다. 여러가지 제약조건으로 해서 최대한으로 송전능력을 향상시켜야 하는 시대적 요청에 부응하여, 미국 PTI사가 주도적으로 행한 연구결과를 중심으로 고다상 송전기술에 대하여 기술한다.