• 제목/요약/키워드: PST

검색결과 299건 처리시간 0.025초

Chlorine-based 유도결합 플라즈마를 이용한 PST 박막의 건식 식각 특성 (Dry etching properties of PST thin films using chlorine-based inductively coupled plasma)

  • 김관하;김경태;김동표;이철인;김창일
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 2003년도 하계학술대회 논문집 Vol.4 No.1
    • /
    • pp.400-403
    • /
    • 2003
  • Etching characteristics of (Pb,Sr)$TiO_3$(PST) thin films were investigated using inductively coupled chlorine based plasma system as functions of gas mixing ratio, RF power and DC bias voltage. It was found that increasing of Ar content in gas mixture lead to sufficient increasing of etch rate and selectivity of PST to Pt. The maximum etch rate of PST film is $562\;{\AA}$/min and the selectivity of PST film to Pt is 0.8 at $Cl_2/(Cl_2+Ar)$ of 20 %. It was proposed that sputter etching is dominant etching mechanism while the contribution of chemical reaction is relatively low due to low volatility of etching products.

  • PDF

Pancastatin A and B Have Selective Cytotoxicity on Glucose-Deprived PANC-1 Human Pancreatic Cancer Cells

  • Park, Hae-Ryong
    • Journal of Microbiology and Biotechnology
    • /
    • 제30권5호
    • /
    • pp.733-738
    • /
    • 2020
  • Glucose deprivation and hypoxia frequently occur in solid tumor cells, including pancreatic cancer cells. Glucose deprivation activates the unfolded protein response (UPR) and causes the up-regulation of glucose-regulated protein 78 (GRP78). Induction of GRP78 has been shown to protect cancer cells. Therefore, shutting down of GRP78 expression may be a novel strategy in anticancer drug development. Based on this understanding, a screening system established for anticancer agents that exhibit selective cytotoxicity on pancreatic cancer cells under glucose-deprived conditions. To test this hypothesis, the new compounds isolated, pancastatin A (PST-A) and B (PST-B), from Ponciri Fructus. PST-A and B were identified as glabretal triterpenoid moieties by electrospray ionization mass spectrometry and nuclear magnetic resonance spectroscopic methods. PST-A and B suppressed the accumulation of the UPR hallmark gene, GRP78, during glucose deprivation. Furthermore, PST-A and B showed selective cytotoxicity on PANC-1 pancreatic cancer cells under glucose deprivation. Interestingly, PST-A and B had no effect on these cells under normal growth conditions. Our results suggest that PST-A and B act as novel therapeutic agents to induce selective cell death in glucose-deprived pancreatic cancer cells.

모바일 PST를 위한 효율적 PA 기법 설계 및 구현 (Design and Implementation of Efficient PA Technology for Mobile PST)

  • 심재성;박석천
    • 한국정보통신학회논문지
    • /
    • 제18권12호
    • /
    • pp.3049-3054
    • /
    • 2014
  • PST는 제품 컨설팅을 위해 제품 카탈로그를 시스템화 한 것으로 대다수의 모바일 PST(Premium Sales Tool)는 DA(Dynamic Allocation)기법을 사용한다. 그러나 모바일 기기는 수용할 수 있는 자원이 한정되어 있어 고해상도의 콘텐츠를 연속적으로 질의 할 경우 요청한 리소스가 대기상태로 쌓여 CPU의 과부하가 발생할 수 있다. 따라서 본 논문에서는 사용자의 제스처에 따라 페이지 할당과 해제를 주기적으로 제공함으로써 부하 발생에 대한 문제를 개선하여 향상된 PST 시스템을 설계 및 구현하였다. 구현한 시스템의 성능을 테스트 한 결과 기존 DA 기반 시스템 보다 제안한 PA(Pattern Allocation) 기반 시스템이 페이지 할당과 해제 빈도수에 대한 부하가 평균 약 78%의 감소율을 보였으며, CPU 점유율은 평균 약72% 감소한 것을 확인하였다.

PST를 기반으로 하는 멀티미디어 프리젠테이션 모델 (A Multimedia Presentation Model Based On PST)

  • 최혜길;최숙영;유관종
    • 한국정보처리학회논문지
    • /
    • 제5권12호
    • /
    • pp.3063-3076
    • /
    • 1998
  • 멀티미디어 프리젠테이션에서 미디어의 함축된 의미를 효과적으로 전달하기 위해서는 미디어 데이터간에 존재하는 시간 및 공간적인 정보를 효과적으로 표현하고 처리할 수 있는 기법이 필요하다. 특히 이들 시간 및 공간 정보는 상호간 긴밀히 연결되어 있기 때문에 종합적인 표현 방법이 요구된다. 따라서 본 논문에서는 시공간의 동기화 정보를 종합적으로 표현하는 프리젠테이션 동기화 트리(PST)를 제안하고 있으며, 이 프리젠테이션 동기화 트리를 이용하여 효과적으로 프리젠테이션을 하는 수행 모델을 제안하고 있다. 특히, 본 모델에서는 사용자가 프리젠테이션을 위한 시나리오를 작성하기 위하여 특정한 사용자 인터페이스나 스크립트 언어를 익힐 필요 없이 Allen의 시간 모델에 기초하여 시간 관계를 간단하게 작성하기만 하면 되며, 실제 프리젠테이션을 위한 나머지 작업들로써 시간 관계의 일관성 검증 단계, PST 수행 단계 등을 거쳐 k동적으로 프리젠테이션 되도록 하였다.

  • PDF

Polystyrene-b-poly(oligo(ethylene oxide) Monomethyl Ether Methacrylate)-b-polystyrene Triblock Copolymers as Potential Carriers for Hydrophobic Drugs

  • You, Qianqian;Chang, Haibo;Guo, Qipeng;Zhang, Yudong;Zhang, Puyu
    • Bulletin of the Korean Chemical Society
    • /
    • 제34권2호
    • /
    • pp.558-564
    • /
    • 2013
  • A simple and effective method is introduced to synthesize a series of polystyrene-b-poly(oligo(ethylene oxide) monomethyl ether methacrylate)-b-polystyrene (PSt-b-POEOMA-b-PSt) triblock copolymers. The structures of PSt-b-POEOMA-b-PSt copolymers were characterized by Fourier-transform infrared spectroscopy (FTIR) and nuclear magnetic resonance ($^1H$ NMR) spectroscopy. The molecular weight and molecular weight distribution of the copolymer were measured by gel permeation chromatography (GPC). Furthermore, the self-assembling and drug-loaded behaviours of three different ratios of PSt-b-POEOMA-b-PSt were studied. These copolymers could readily self-assemble into micelles in aqueous solution. The vitamin E-loaded copolymer micelles were produced by the dialysis method. The micelle size and core-shell structure of the block copolymer micelles and the drug-loaded micelles were confirmed by dynamic light scattering (DLS) and transmission electron microscopy (TEM). The thermal properties of the copolymer micelles before and after drug-loaded were investigated by different scanning calorimetry (DSC). The results show that the micelle size is slightly increased with increasing the content of hydrophobic segments and the micelles are still core-shell spherical structures after drug-loaded. Moreover, the glass transition temperature (Tg) of polystyrene is reduced after the drug loaded. The drug loading content (DLC) of the copolymer micelles is 70%-80% by ultraviolet (UV) photolithography analysis. These properties indicate the micelles self-assembled from PSt-b-POEOMA-b-PSt copolymers would have potential as carriers for the encapsulation of hydrophobic drugs.

고랭지 착색단고추의 접목재배 효과 (Effects of Grafting Cultivation on the Growth and Yield of Paprika in Highlands)

  • 이종남;이응호;김점순;김원배;류승열;용영록
    • 생물환경조절학회지
    • /
    • 제13권1호
    • /
    • pp.33-38
    • /
    • 2004
  • 본 시험은 고랭지에서 착색단고추의 접목재배로 토경재배시 지하부 환경개선을 통해 토양전염성 병을 예방하고, 수량성을 향상시키고자 저항성 대목들을 수집하여 접목재배하여 생육, 수량 및 병저항성을 비교하였다. 접수는 적색계인 스피리트품종을 사용하였다. 역병균을 접종한 결과 자근묘인 Spirit는 접종 후 5일 만에 100% 고사하였고, 저항성이 높은 대목으로는 탄탄대목, Skurt-S, AC 2258, PST 8301 등 4품종이었다. 또한 청고병에 저항성이 높은 대목으로는 역강, 탄탄대목, TE 412, 갤럭시, MC 4, PST VK, PST NV 등 7품종이었다. 접목구는 지근묘에 비해 근중이 무거워 지하부의 환경개선효과가 뚜렷하였다. 접목과 비접목에 따른 과실의 외적 ${\cdot}$ 내적인 품질은 큰 차이가 없었다. 수량성이 높은 대목은 PST 8301, MC 4, 왕건 등이었다.

PST(Particle Streak Tracking)시스템을 통한 실내자연환기 경향분석 (Tendency Analysis of Indoor Natural Ventilation by PST(Particle Streak Tracking) System)

  • 이건호;김현수;장대희;손영주
    • KIEAE Journal
    • /
    • 제7권6호
    • /
    • pp.9-15
    • /
    • 2007
  • Ventilation of buildings provide occupants with comfort and plays a very informant role in supplying indoor ventilation requirement. Also, natural ventilation is more comfortable than forced ventilation taking account of mental comfort. Especially factors, airflow velocity and direction etc., should be reflected in establishment of comfortable indoor environment because indoor airflow can directly affect comfort of occupants. However, a device which enables indoor air movement to be analyzed has not existed until now. Hence, it has mostly depended on simulation results of fluid analysis but the results often differ far from reality. PST(Particle-Streak-Tracking) System, an alternative to improve this problem, is currently applied to natural ventilation in building, air conditioning, and airflow analysis in the inside of a plane etc. This study closely examine the property and strength and weakness of PST that is first introduced into KICT and then evaluate applicable possibility.

유도결합 플라즈마를 이용한 PST 박막의 식각 특성 및 이온 에너지 분포 (Etching characteristics of PST thin film and ion energy distribution using inductively coupled plasma)

  • 김관하;김경태;김창일
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2004년도 추계학술대회 논문집 전기물성,응용부문
    • /
    • pp.98-100
    • /
    • 2004
  • In this study, PST thin films were etched with inductively coupled $Cl_2/(Cl_2+Ar)$ plasmas. The etch characteristics of PST thin films as a function of $Cl_2/(Cl_2+Ar)$ gasmixtures were analyzed by using quadrupole mass spectrometer (QMS). Systematic studies were carried out as a function of the etching parameters, including the RF power and the working pressure. The maximum PST film etch rate is 56.2 nm/min, because a small addition of $Cl_2$ to the $Cl_2$/Ar mixture increased the chemical effect. It was proposed that sputter etching is the dominant etching mechanism while the contribution of chemical reaction is relatively low due to low volatility of etching products.

  • PDF

The Pst 1 Polymorphism of the Human Apolipoprotein AI Gene in Korean Elite Athletes

  • Kang, Byung-Yong;Kim, Hyun-Hee;Lee, Kang-Oh
    • Animal cells and systems
    • /
    • 제7권1호
    • /
    • pp.69-73
    • /
    • 2003
  • Serum lipid and lipoprotein levels are influenced by genetic factors, and exorcise increases the concentrations of cardio-protective parameters such as high-density lipoprotein cholesterol (HDL-cholesterol) and apolipoproteinAI (apoAI) in human serum. In the present study, we tested the effect of adaptation to endurance exercise on the association of a genetic polymorphism (Pst 1 RFLP) in the apoAI gene with these biochemical parameters. The genotype and allele frequencies for the Pst 1 RFLP were not significantly different between the elite athletes and sedentary controls (P>0.05). There were also no significant associations between the Pst 1 RFLP of the apoAI gene and the biochemical parameters in elite athletic group. Thus, our results suggest that the Pst 1 RFLP of the apoAI gene was not significantly associated with the serum apoAI and HDL-cholesterol concentrations as well as athletic performance in Koreans.

Activation of Defense Responses in Chinese Cabbage by a Nonhost Pathogen, Pseudomonas syringae pv. tomato

  • Park, Yong-Soon;Jeon, Myeong-Hoon;Lee, Sung-Hee;Moon, Jee-Sook;Cha, Jae-Soon;Kim, Hak-Yong;Cho, Tae-Ju
    • BMB Reports
    • /
    • 제38권6호
    • /
    • pp.748-754
    • /
    • 2005
  • Pseudomonas syringae pv. tomato (Pst) causes a bacterial speck disease in tomato and Arabidopsis. In Chinese cabbage, in which host-pathogen interactions are not well understood, Pst does not cause disease but rather elicits a hypersensitive response. Pst induces localized cell death and $H_2O_2$ accumulation, a typical hypersensitive response, in infiltrated cabbage leaves. Pre-inoculation with Pst was found to induce resistance to Erwinia carotovora subsp. carotovora, a pathogen that causes soft rot disease in Chinese cabbage. An examination of the expression profiles of 12 previously identified Pst-inducible genes revealed that the majority of these genes were activated by salicylic acid or BTH; however, expressions of the genes encoding PR4 and a class IV chitinase were induced by ethephon, an ethylene-releasing compound, but not by salicylic acid, BTH, or methyl jasmonate. This implies that Pst activates both salicylate-dependent and salicylate-independent defense responses in Chinese cabbage.