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The Pst 1 Polymorphism of the Human Apolipoprotein AI Gene in Korean Elite Athletes  

Kang, Byung-Yong (Research Institute for Life Science, Sahmyook University)
Kim, Hyun-Hee (Dept. of Life Science, Sahmyook University)
Lee, Kang-Oh (Dept. of Life Science, Sahmyook University)
Publication Information
Animal cells and systems / v.7, no.1, 2003 , pp. 69-73 More about this Journal
Abstract
Serum lipid and lipoprotein levels are influenced by genetic factors, and exorcise increases the concentrations of cardio-protective parameters such as high-density lipoprotein cholesterol (HDL-cholesterol) and apolipoproteinAI (apoAI) in human serum. In the present study, we tested the effect of adaptation to endurance exercise on the association of a genetic polymorphism (Pst 1 RFLP) in the apoAI gene with these biochemical parameters. The genotype and allele frequencies for the Pst 1 RFLP were not significantly different between the elite athletes and sedentary controls (P>0.05). There were also no significant associations between the Pst 1 RFLP of the apoAI gene and the biochemical parameters in elite athletic group. Thus, our results suggest that the Pst 1 RFLP of the apoAI gene was not significantly associated with the serum apoAI and HDL-cholesterol concentrations as well as athletic performance in Koreans.
Keywords
Apolipoprotein AI; Athletic Performance and Serum;
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Times Cited By KSCI : 3  (Citation Analysis)
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