• BMB Reports
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• v.52 no.9
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• pp.548-553
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• 2019

Ets-1 is a prototype of the ETS protein family. Members of the ETS protein family contain a unique ETS domain. Ets-1 is associated with cancer progression and metastasis in many types of cancer. Many studies have shown a link between elevated expression of Ets-1 in cancer biopsies and poor survival. CCR7 is a chemokine that binds to specific ligand CCL21/CCL19. CCR7 expression is associated with tumor metastasis and infiltration into lymph nodes. The objective of this study was to test whether Ets-1 could regulate CCR7 expression and enhance tumor metastasis. Our data showed that CCR7 expression was downregulated in Ets-1-deficient T cells upon T-cell stimulation. Overexpression of Ets-1 increased CCR7 expression in breast cancer cell lines. In contrast, knockdown of Ets-1 reduced CCR7 expression. Ets-1 could directly bind to CCR7 promoter and mediate CCR7 expression in luciferase reporter assays and chromatin immunoprecipitation assays. Transactivation activity of Ets-1 was independent of the Pointed domain of Ets-1. Ets-1 could also enhance $NF-{\kappa}B$ and CBP transactivation of CCR7 promoter. Our results also showed that Ets-1 could modulate cancer cell transmigration by altering CCR7 expression in transwell assay and wound healing assay. Taken together, our data suggest that Ets-1 can enhance CCR7 expression and contribute to tumor cell migration.

• Journal of Advanced Navigation Technology
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• v.23 no.5
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• pp.437-443
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• 2019

In this paper, a new algorithm for the calculation of the range between an LTE base station (BS) and a user equipment (UE) using time-of-arrival (TOA) measurements of LTE signals is proposed. First, the cell identity (cell ID) of the received signal is acquired using the primary synchronization signal (PSS) and secondary synchronization signal (SSS) to identify the BS transmitted the signal. The proposed algorithm exploits the cell-specific reference signal (CRS), the reference sequence inserted in commercial LTE signals, to estimate the time delay using 2D cross-correlation. The obtained TOA estimations can be used to calculate the range employed from the known BS location. The performance of the proposed algorithm is evaluated with the experiment performed using real LTE signals transmitted from the commercial BS.

• Journal of Korean Port Research
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• v.10 no.1
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• pp.1-14
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• 1996

Rapid change in the technological environment of marine transportation and the development of the ocean shipping industry have fostered a revolution in the port system. This in turn has caused major changes in the function and use of port in Korea. Aside from this, Mokpo Port, however continues to decline, because the existing port facilities and related subsystem are already obsolete with no chance of regaining operational effectiveness and treatment for proper implementation. Although a few studies have been done on the Mokpo Port, has not been found, any reseach for the analytical approach to the transportation system of it. This paper aims to make an extensive analysis of the physical distribution system in Mokpo Port focusing on the coordination of subsystems such as navigational aids system. The base of introduced simulation tool here is the queueing theory. The overall findings are as follows: 1. Among those vessels called at Mokpo Port in 1994, 556 ships(2,736,669 G/T) are oceangoing while 8155 ships(2,587,217 G/T) are domestic. The average size of oceangoing vessels is 4,922,1 G/T, and the domestic is 317,8 G/T. The average arrival interval and service time of the domestic vessels are 6.0 hours and 24.1 hours respectively marking the berth occupation rate over 100%. Those for oceangoing vessels are 34.5 hours, 120.0 hours and 37.2%. In order to maintainin the berth occupation rate to 70% the capacity considering the 1994 of domestic piers must be extended to 145% and oceangoing vessels must be increased to 165%. 2. The capacity of approaching channel is enough to handle the total traffic volume of 3. Tugs are sufficiently being provided to handle all ships requiring their services 4. The capacity of storage and inland transportation systems are sufficient to handle the throughput and the yard stroage utilization rate of No.1 - No.5 is 4.5% and No.6 is 30% of 1993's. 5. The utilization rate of LLC(Level Looping Crane) and PNT(PNeumaTic) are 2.7% and 18.8%, respectively.

• Advances in nano research
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• v.15 no.1
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• pp.59-65
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• 2023

In this present article, the mechanical behavior of single-walled black phosphorene nanotubes (SW-αPNTs) is simulated using molecular dynamics (MD). The proposed model is subjected to the axial loading and the effects of morphological parameters, such as the mono-vacancy defect and strain rate on the tensile behavior of the zigzag and armchair SW-αPNTs are studied as a pioneering work. In order to assess the accuracy of the MD simulations, the stress-strain response of the current MD model is successfully verified with the efficient quantum mechanical approach of the density functional theory (DFT). Along with reproducing the DFT results, the accurate MD simulations successfully anticipate a significant variation in the stress-strain curve of the zigzag SW-αPNTs, namely the knick point. Predicting such mechanical behavior of SW-αPNTs may be an important design factor for lithium-ion batteries, supercapacitors, and energy storage devices. The simulations show that the ultimate stress is increased by increasing the diameter of the pristine SW-αPNTs. The trend is identical for the ultimate strain and stress-strain slope as the diameter of the pristine zigzag SW-αPNTs enlarges. The obtained results denote that by increasing the strain rate, the ultimate stress/ultimate strain are respectively increased/declined. The stress-strain slope keeps increasing as the strain rate grows. It is worth noting that the existence of mono-atomic vacancy defects in the (12,0) zigzag and (0,10) armchair SW-αPNT structures leads to a drop in the tensile strength by amounts of 11.1% and 12.5%, respectively. Also, the ultimate strain is considerably altered by mono-atomic vacancy defects.

• Journal of Advanced Navigation Technology
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• v.28 no.1
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• pp.1-14
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• 2024

Global navigation satellite system (GNSS) providing position, navigation and timing (PNT) services consist of satellite, ground, and user systems. Monitoring stations, a key element of the ground segment, play a crucial role in continuously collecting satellite navigation signals for service provision and fault detection. These stations detect anomalies such as threats to the signal-in-space (SIS) of satellites, receiver issues, and local threats. They deliver received data and detection results to the master station. This paper introduces the main monitoring algorithms and measurement pre-processing processes for quality assessment and fault detection of received satellite signals in current satellite navigation system monitoring stations. Furthermore, it proposes a strategy for the development of components, architecture, and algorithms for the new regional navigation satellite system (RNSS) monitoring stations.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.9
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• pp.1822-1829
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• 2016

DGPS Reference station is established in Korea for improvement of GPS navigation accuracy and needs of integrity. Recently, DGPS stations provide user positioning information on land as well as ocean. However, this paper investigated visibility and interference environment for performance degradation of Chung-ju DGPS reference station. In case of Young-do reference station, visibility and interference environment were satisfied with reference standard. In case of Chung-ju reference station, visibility was satisfied with 7 degree elevation angle. However, interference environment was not satisfied with reference standard of -50dBm. This paper proposed time differential measurement analysis method excluding error of signal noise for analyzing measurement error. Chung-ju reference station measurement analysis result is three times the error than on Young-do in Dec, 2015. In addition, this paper has confirmed measurement performance degradations because of reference station equipment problem. Future study will be carried out performance analysis of 17 DGPS reference station.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2015.10a
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• pp.279-282
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• 2015

Fisheries development of the basic law pursuant to article 15 (marine safety management, etc.) one of maritime safety and maritime traffic facilities nationwide network of DGPS in accordance with the building maximize infrastructure utilization and country. Source technology has been improving steadily raised for the benefit daegukmin. In particular, look at the type of product for the marine supply medium-wave receiver Performance products that satisfy most of the IMO Advisory. The antenna and receiver are separate structural supply for some integrated model with a very high Rather it is used as a portable receivers for marine positioning cheap integrated model development is needed. Correction of satellite navigation receivers for the current Marine GPS module, medium-wave modules can be developed one low cost Integrated in independent operating environments do not support the model development done look at what the problem is 285kHz ~ 315kHz in DGPS Beacon receiver structure using a medium wave or Beacon The medium-wave antenna and a GPS receiver signal to noise ratio was studied GPS signal attenuation on the DGPS performance looked at each GPS manufacturer medium-wave signal-to-noise ratio and normalized impact by GPS manufacturers noise power ratio per bandwidth for medium-wave GPS signals affect it was implemented to improve performance.

• Journal of Navigation and Port Research
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• v.43 no.3
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• pp.172-178
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• 2019

Although the needs for providing resilient PNT information are increasing, threats due to the intentional RFI or space weather change are challenging to resolve. eLoran, which is a terrestrial navigation system that use a high-power signal is considered as a best back-up navigation system. Depending on the user's environment in the eLoran system, the user may use one of E-field or H-field antennas. H-field antenna, which has no restriction on setting stable ground and is relatively resistant to noise of general electronic equipment, is composed of two loops, and shows anisotropic gain pattern due to the different measurement at the two loops. Therefore, the H-field antenna's phase estimation value of signal varies depending on its direction even at the static environment. The error due to the direction of the signal should be eliminated if the user want to estimate the own position more precisely. In this paper, a method to compensate the error according to the geometric distribution between the H-field antenna and the transmitting station is proposed. A model was developed to compensate the directional error of H-field antenna based on the signal generated from the eLoran signal simulator. The model is then used to the survey measurement performed in the land area and verify its performance.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.25 no.11
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• pp.1588-1595
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• 2021

Android-based smartphones receive the global navigation satellite system (GNSS) signals to determine their location and provide the GNSS raw measurement to users. The available GNSS signals on the current Android devices are GPS, GLONASS, Galileo, BeiDou, QZSS. This research has analyzed the performance of multi-GNSS position accuracy based on the pseudorange of the smartphone for maritime users. Smartphones capable of receiving dual-frequency are installed on a ship, and multi-GNSS raw information in maritime environment was measured to present the results of comparing the GNSS pseudorange-based dual-frequency positioning performance for each smarphone. Furthermore, we analyzed whether the results of the positioning performance can meet the HEA requirement of IMO for maritime navigation users. As the results of maritime experiment, it was confirmed that in the case of the smartphones supporting the dual-frequency, the position accuracy within 6 meters (95%) could be obtained, and the HEA position accuracy performance within 10 meters (95%) required by IMO could be achieved.

• Journal of Korean Port Research
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• v.11 no.2
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• pp.321-337
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• 1997

Rapid change in the technological environment of marine transportation and the development of the ocean shipping industry have fostered a revolution in the port system. This in turn has caused major changes in the function and use of port in Korea. Aside from this. Mokpo Port, however continues to decline, because the existing port facilities and related subsystem are already obsolete with no chance of regaining operational effectiveness and treatment for proper implementation. Although a few studies have been done on the Mokpo Port, has not been found, any reseach for the analytical approach to the transportation system of it. This paper aims to make an extensive analysis of the physical distribution system in Mokpo Port focusing on the coordination of subsystems such as navigational aids system, quay handling and transfer system, storage system and inland transport system. The base of introduced simulation tool here is the queueing theory. The overall findings are as follows; 1. Among those vessels called at Mokpo Port in 1994, the average size of oceangoing vessels is 4,922.1 G/T, and the domestic is 317.8 G/T. The average arrival interval and service time of the domestic vessels are 6.0 hours and 24.1 hours respectively marking the berth occupation rate over 100%. Those for oceangoing vessels are 34.5 hours, 120.0 hours and 37.2%. In order to maintainin the berth occupation rate to 70% the capacity considering the 1994 of domestic piers must be extended to 145% and oceangoing vessels must be increased to 165% year called. 2. The capacity of approaching channel is enough to handle the total traffic volume. 3. Tugs are sufficiently being provided to handle all ships requiring their services 4. The capacity of storage and inland transportation systems are sufficient to handle the throughput and the yard stroage utilization rate of No.1 $\cdots$ No.5 is 4.5% and No.6 1S 30% of 1993's. 5. The utilization rate of LLc(Level Looping Crane) and PNT(PNeumaTic) are 2.7% and 18.8%, respectively. Practical solution and proposal for improvement of Transportation System in Mokpo Port are as follows; 1. To avoid the congestion in domestic pier introduction of a new port operation system is necessary allowing the domestic vessel to use the oceangoing pier. 2. To establish the port management information system to improve the efficiency of port operation. 3. To build a new storage system for high valued cargos including modernization of the present storage and handling system. 4. To insure the safety of navigation in approaching channel, The Vessel Traffic System including separation scheme is introduced. 5. To interest enormously on public relation to ship owner's association, shippers and consignees by showing that they can save cost and ship turnaround time in order to promote the call to Mokpo Port. At last, to be strategically change the function of Mokpo Port to the Leisure, Fishing & Ferry as well as Maritime port.