• Reproductive and Developmental Biology
• /
• v.39 no.3
• /
• pp.83-88
• /
• 2015

The present study was devised to determine the effects of vitamin E and selenium (Selevit) on body weight, organ weight, hematological values and biochemical parameters in the orchidectomized (Orch) rats. Intact group (n=15) received no treatment and operation. Orch+Selevit received operation and Selevit. The body weights of each group increased, but that of the Orch＋Selevit group were significantly lower than those of all the other groups. There were significantly different decreased (p<0.001) of body weights between Orch＋Selevit group and all the other groups. Also, organ weights such as heart, liver, spleen, kidney, lung and skeletal muscle were measured. The heart and liver weights in the Orch＋Selevit group were significantly different decreased (p<0.001) in comparison with those in the Intact and Sham groups. The kidney weights in the Orch＋Selevit group were significantly different decreased (p<0.01, p<0.001) in comparison with those in all the other groups. The number of white blood cell (WBC) was significantly higher (p<0.05) in the Orch＋Selevit group than in all the other groups. The hematological values of 12 parameters were not significantly different in any of the groups. The concentrations of serum total protein, albumin and alkaline phosphatase only increased significantly (p<0.05, p<0.01) in the Orch＋Selevit group as compared to that in the Orch group. We conclude that Selevit was significantly decreased the body weight in the Orch rats. Our findings suggest that Selevit may influence the process of lipid packaging and absorption in the Orch rats.

• Journal of Veterinary Clinics
• /
• v.30 no.4
• /
• pp.258-263
• /
• 2013

The primary goal of this study was to compute sample sizes required to achieve the each aim of a variety of foot-and-mouth disease (FMD) surveillance programs, using a statistically valid technique that takes the following factors into account: sensitivity (Se) and specificity (Sp) of diagnostic test system, desired minimum detectable prevalence, precision, population size, and desired power of the survey. In addition, sample sizes to detect FMD if the disease is present and also as proof of freedom were computed. The current FMD active surveillance programs consist of clinical, virological, and serological surveillance. For the 2012 serological surveillance, annual sample sizes (n = 265,065) are planned at four separate levels: statistical (n = 60,884) and targeted (n = 115,232) at breeding pig farms and slaughter house, in together with the detection of structural proteins (SP) antibodies against FMD (n = 88,949). Overall, the sample size was not designed taking the specific aims of each surveillance stream into account. The sample sizes for statistical surveillance, assuming stratified two-stage sampling technique, was based to detect at least one FMD-infected case in the general population. The resulting sample size can be used to obtain evidence of freedom from FMD infection, not for detecting animals that have antibodies against FMD virus non-structural proteins (NSP). Additionally, sample sizes for targeted surveillance were not aimed for the population at risk, and also without consideration of statistical point of view. To at least the author's knowledge, sampling plan for targeted, breeding pig farms and slaughter house is not necessary and need to be included in the part of statistical surveillance. Assuming design prevalence of 10% in an infinite population, a total of 29 animals are required to detect at least one positive with probability of 95%, using perfect diagnostic test system (Se = Sp = 100%). A total of 57,211 animals needed to be sampled to give 95% confidence of estimating SP prevalence of 80% at the individual animal-level with a precision of ${\pm}5%$, assuming 800 herds with an average 200 heads per farm, within-farm variance of 0.2, between-farm variance of 0.05, cost ratio of 100:1 of farm against animals. Furthermore, 779,736 animals were required to demonstrate FMD freedom, and the sample size can further be reduced depending on the parameters assumed.

• Journal of Society of Preventive Korean Medicine
• /
• v.13 no.1
• /
• pp.41-58
• /
• 2009

Objectives: The purpose of this study was to investigate the effects of Hyolbuchukeo-tang extracts on the hyperlipidemia rats induced by high fat diet. Methods and Materials: In vitro; The extracts prepared for Hyolbuchukeo-tang by hot water extraction (HH), fermentation(HF) and UMPM extraction(HU) method. The extracts were examined for levels of polyphenol compounds, antioxidant activities, and inhibitory potencies for HMG-CoA reductase. In vivo; Sprague-Dawley male rats of weighing $150{\pm}5g$ were randomly divided into six groups ; normal control diet(NC), and high fat diet(HC), high fat diet with treated lovastatin of 10mg/kg(PC), high fat diet with Hyolbuchukeo-tang extracts; HH, HF and HU treated extracts of 300mg/kg, respectively. Also, we compared the effects of the extracts of HH, HF and HU on rats fed high fat diet for four weeks. Results: 1. The content of polyphenol compounds and electron donating abilities(EDAs) was the HF higher than HH and HU. The superoxide dismutase(SOD)-like activities were proportionate in consistency and they appeared highly from all extracts. The HMG-CoA reductase inhibition activities was highest activities in the HU. 2. The activities of serum GOT and GPT were significantly lower in the HH and HF groups. The level of serum triglyceride was significantly decreased in the HF group. HH and HU groups were significantly decreased in the atherogenic index(AI). The total cholesterol concentration in liver was significantly decreased in the HF group, and HU showed more significantly decreased in the triglyceride than of the lovastatin. Also, photomicrographs of liver tissue showed higher fat accumulation in the HC group than in the HH, HF and HU groups. Conclusions: These result suggest that the hyper-lipidemia caused by a high fat diet was effectively inhibited the administration of HF and HU.

• Journal of Chest Surgery
• /
• v.48 no.3
• /
• pp.180-186
• /
• 2015

Background: Extracorporeal membrane oxygenation (ECMO) has recently attracted interest as a treatment for severe acute respiratory distress syndrome (ARDS). However, the outcomes of this procedure in post-surgical settings have not yet been characterized. In this study, we evaluated the outcomes of ECMO in patients with severe postoperative ARDS. Methods: From January 2007 to December 2012, a total of 69 patients (aged $58.3{\pm}11.5$ years, 23 females) who underwent venovenous ECMO to treat severe postoperative ARDS were reviewed. Of these patients, 22 (31.9%) had undergone cardiothoracic surgery, 32 (46.4%) had undergone liver transplantation, and 15 (21.7%) had undergone other procedures. Results: Thirty-four patients (49.3%) were successfully weaned from ECMO, while the other 35 patients (50.7%) died on ECMO support. Among the 34 patients who were successfully weaned from ECMO, 21 patients (30.4%) eventually died before discharge from the hospital, resulting in 13 hospital survivors (18.8%). Multivariable analysis showed that the duration of pre-ECMO ventilation was a significant independent predictor of death (odds ratio [OR], 2.25; 95% confidence interval [CI], 1.29 to 3.90; p=0.004), whereas the concomitant use of continuous venovenous hemodialysis (CVVHD) was associated with improved survival (OR, 0.55; 95% CI, 0.31 to 0.97; p=0.038). Conclusion: Although the overall survival rate of patients treated with ECMO for postoperative ARDS was unfavorable, ECMO offered an invaluable opportunity for survival to patients who would not have been expected to survive using conventional therapy. CVVHD may be beneficial in improving the outcomes of such patients, whereas a prolonged duration of pre-ECMO ventilator support was associated with poor survival.

• Korean Journal of Food Science and Technology
• /
• v.41 no.3
• /
• pp.258-264
• /
• 2009

The principal objective of this study was to estimate the measurement uncertainty associated with determination of deoxynivalenol (DON), a mycotoxin generated by Fusarium strain, in food. In service of this goal, wheat as a food matrix was analyzed via high performance liquid chromatography-ultraviolet (HPLC-UV) detection using an immunoaffinity column for clean-up. The uncertainty sources in the measurement process were identified by sample weight, final volume, and sample concentration in extraction volume with components including standard stock solution, working standard solution, 5 standard solutions, calibration curve, matrix, and instrument. The expanded uncertainty for DON at a concentration of 300 ${\mu}g/kg$ was estimated as 71.62 ${\mu}g/kg$ using a coverage factor of two, which provides a confidence level of approximately 95%. The most influential component in the uncertainty sources was the recovery of the wheat matrix, followed by the calibration curve. These results indicate that all efforts may be directed toward reducing the uncertainties of the recovery of the wheat matrix and the calibration curve to obtain a reliable HPLC-UV method for DON analysis in wheat.

• Korean Journal of Food Science and Technology
• /
• v.13 no.2
• /
• pp.153-159
• /
• 1981

A study was carried out to determine the optimal sterilization conditions of cooked rice packed in retort pouch and processed in a steam-air system retort. The cooked rice packed in retort pouch in various thickness (15, 20 and 25 mm) was processed at various heating temperature (110, 115 and $120^{\circ}C$) with $F_0$-value 6.0. In order to evaluate quality change during the thermal prosessing, C-values, based on z-value $33^{\circ}C$ and $F_0$ value 6.0, were also calculated at surface, center and mass average temperatures. Subsequent storage study revealed that the cooked rice packed in 15 mm thickness and processed at $120^{\circ}C$ with$F_0$-value 6.0 could be held without any spoilage and color change, when stored for 6 months at $38{\pm}1^{\circ}C$ under saturation humidity.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.19 no.5
• /
• pp.1272-1280
• /
• 2005

The study was performed by examining the effects of fermented liquid of Crataegi Fructus on the lipid profile improvement in rats fed high fat diets. Sprague-Dawley rats of weighting $180.0{\pm}30g$ were randomly divided into five groups : basal diet (Normal control group, NCG), only high fat diet (High fat control group, HFC), high fat diet and supplemented with 1.69 mg/100 g body weight, 3.38 mg/100 g body weight, 6.76 mg/100 g body weight by fermented liquid of Crataegi Fructus - HFL, HFM, HFH group). These experimental diets were fed for 6 weeks. The fermented liquid of Crataegi Fructus fed groups had more significantly decreased in the levels of serum total cholesterol, triglyceride, LDL-cholesterol and atherogenic index than the high fat control group, while the HDL-cholesterol was higher when compared to the normal control group. Total lipid, total cholesterol, triglyceride, LDL-cholesterol contents in liver were decreased in high fat experimental groups. But the degree of increment was reduced by administration of fermented liquid of Crataegi Fructus. while the fermented liquid of Crataegi Fructus fed group had ore significantly increased in the level of HDL-cholesterol than the high fat control group. The singularity of the unsaturated fatty acid contents attracted our attention. Especially, the polyunsaturated fatty acid compositions were 36.36%, 34.70%, 20.31%in serum, liver and fecal of fermented liquid of Crataegi Fructus fed groups, respectively. These results imply that the fermented liquid of Crataegi Fructus can be used as possible food resources and medicinal food materials.

• Journal of the Mineralogical Society of Korea
• /
• v.26 no.4
• /
• pp.331-342
• /
• 2013

동아프리카 열곡대는 아라비아반도와 아프리카 북동부의 경계에서 부채꼴 형태로 남쪽으로 뻗은 대단층 함몰지구대이다. 아프리카 판 내부에 발달한 열곡대의 폭은 35~60 km이며 연장은 약 4,000km로 알려져 있다. 열곡대는 에티오피아에서 남서방향으로 발달하다 에티오피아 남부에서 동, 서 및 남서 열곡대로 나누어진다. 이 열곡대는 제3기초 올리고세(30~35 Ma)부터 에티오피아 북부 아파르 침강대를 중심으로 주 에티오피아 열곡대가 형성되고, 남쪽으로 확장되면서 마이오세에 활성화된다. 서부 열곡대는 동아프리카대지의 가장자리와 빅토리아 호의 서편을 따라 발달하며, 고각의 정단층에 의해 특징되는 전형적인 반지구대이다. 동부 열곡대(주 에티오피아 열곡대와 케냐 열곡대)는 30 Ma 전 화산활동과 지구조활동이 시작되었으나, 서부 열곡대는 Albert 호 북부에서 12 Ma 전에, Tanganyika 열곡에서는 7 Ma 전부터 시작되었다. 서부 열곡대의 남서 방향으로 분기된 남서 열곡대는 DR-콩고 남부와 잠비아의 Tanganyika 호에서부터 남서 방향으로 확장되어 보츠와나 Okavango 열곡대와 연결된다. 주 에티오피아 열곡대(MER)의 화산암류와 관련 퇴적암류는 지열, 소다회, 포타쉬(K), 천열수 금, 벤토나이트, 유황 및 부석자원으로 중요한 관련암으로 역할을 한다. 열곡관련 대표적인 광상으로는 Afar 열곡대에 분포하는 Danakhil K-광상과 Megenta 및 Blackrock 천열수 금광상이다. Danakhil K-광상은 제4기 화산활동과 높은 지열류에 의해 열곡대 내 분포하던 소금 선상지(salt fan)에서 증발작용에 의해 형성된 증발형 K-광상으로서 총 자원량은 약 12.6억톤으로 평가되었다. 이 광상에서는 4종의 K-광물인 실바이트, 카날라이트, 포리하라이트, 카이나이트가 산출한다. 아파르 침강대 내 분포하는 대표적인 천열수 금광상은 텐다호 지구대에 위치하는 Megenta 및 Blackrock 광상이다. 제4기에 EMR에서 산성의 과알칼리 화산활동에 의해 열수활동이 초래되어 현재까지도 활동하여 지열대가 형성되고, 저유황형금 광상들이 형성되었다. Megenta 저유황형 금 광상은 2009년 발견되었으며, 현재 영국의 Startex International사에 의해 탐사가 진행 중이다. 지금까지의 탐사 결과 옥수질 규화 변질암 분포지에서 5개의 광체가 분포하며, 그중 Hyena 광체에서는 규화 변질된 열수각력암에서 최고 16.75 g/t의 금 품위가 보고되었다. 동아프리카 열곡대의 서편인 부룬디에 분포하는 Gakara REE 광상은 카보너타이트 유형의 REE 광상이다. 이 광상은 $400km^2$ 면적 내 수 cm부터 수 m까지의 폭을 가지는 맥상 또는 망상세맥상의 광체를 형성한다. 주로 조립의 바스트너사이트와 모나자이트로 구성된다. 바스트너사이트의 형성시기는 $587{\pm}4Ma$인 신원생대로 알려져 있으며, 이 지역에 분포하는 카보너타이트와 알칼리암들이 신원생대에서 신생대까지의 광범위한 연대를 보이는 것은 동일한 구조선을 따라서 일어나는 반복되는 열곡활동으로 해석된다. 또한 REE, U, 인회석 자원의 관련암체로 생각되는 알카리 조면암(네펠린-조면암 포함)과 카보너타이트는 동아프리카 열곡대의 남동부 끝자락인 말라위와 모잠비크에 우세하게 분포한다.

• Korean Journal of Food Science and Technology
• /
• v.35 no.5
• /
• pp.877-883
• /
• 2003

Multi-degradable master hatch (M/B) was prepared and 0.05 mm polyethylene (PP) food packaging films containing 0, 10, and 20% M/B were manufactured by inflation film processing. The films were exposed to UV radiation, fungi, and heat in order to observe their photolysis, biodegradability, and thermal degradability, respectively. While pure PP film maintained more than 70% of its original elongation after 8 weeks of UV radiation, an almost perfect loss in the elongation of PP film containing 20% M/B was observed. Significant decreases in elongation of PP films by heat treatment $(68{\pm}2^{\circ}C)$ were also found in samples containing the multi-degradable M/B. By observing changes in film surface after the inoculation of fungi using scanning electron microscopy (SEM), the biodegradability of plastic film could be accelerated with the addition of multi-degradable M/B. The results of the mulching test in yard showed that adding multi-degradable M/B can effectively degrade plastic films in natural environmental conditions without interrupting the growth of plants.

• Korean Journal of Occupational Health Nursing
• /
• v.8 no.1
• /
• pp.56-67
• /
• 1999

This study was designed to identify the relationships of role-conflict and role-overload, coping strategies, and stress response of clerical workers. The subjects were 115 clerical workers from two company. The instruments were the role-conflict and role-overload scale developed by Lee(1989), coping scale developed by Latack(1986), and the stress response scale developed by Chang(1993). Analysis of data was done by descriptive statistics, Cronbach's $\alpha$, Pearson correlation coefficietnt, ANOVA. The results of this study were summarized as follows ; 1. The average score for the level of stress response was $83.6({\pm}9.1)$. The high risk stress group was 86.1% of the clerical workers, the latent stress group members was 13.9%, and healthy group was 0%. The overall stress level was very high. 2. Considering the coping strategies by sociodemographic factors, the use of control coping strategies showed significant differences by work-time. The use of symptom management coping strategies showed significant differences by sex, age, married status, year of career, pay, and type of work. The organizational coping strategies showed significant differences by year of education and type of work. 3. The clerical workers who had worked below 44 hours per week complained significantly lower stress response(F=4.942, p<.05). 4. Above 65% of all respondents answered that they needed all of organizational level coping strategies. 5. The role-confilct positively related to escape and organizational level coping strategies(r=.562, r=.495, p<.05). The role-overload didn't related to individual level coping strategies, but positively related to organizational level coping strategies(r=.320, p<.05). 6. The control coping strategies and the escape coping strategies positively related to symptom management, organizational level coping strategies(r=.409, r=.324, r=.316, r=.339, p<.05). 7. The relationship between role-related stress and stress response revealed positive correlation(r=.482, r=.431, p<.05), and the relationship between stress response and control, symptom management coping strategies revealed negative cor-relation(r=-.3204, r=-.3146, p<.05). In conclusion, this study revealed that relationship of role related stress, coping strategies, stress response was statistically significant. The result of this study support that coping strategies vary across situation of stress. Based on survey results, future studies should consider coping strategies in specific stress situation and concept of symptom management coping strategy. Also organizational or training interventions could be developed and initiate to help to increase the use of adaptive coping strategies in light of individual and situational differences.