• Korea Trade Review
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• v.48 no.2
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• pp.71-94
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• 2023

The purpose of this study is to prove the effect of psychic distance between home country and host country on overseas foreign direct investment(OFDI) of Spanish companies through panel analysis. The panel data was based on cultural, institutional, economic, and geographical distance data over the past decade between Spain and Spain's OFDI countries. According to the Random Effect Model(REM) analysis, cultural distance(CULD) had a negative effect on OFDI, while institutional distance(INSD) had a positive effect. Among economic distances, income size distance(GDP) had a positive effect on OFDI, but export size distance(EXPO) had a negative effect. Geographic distance(PKM) had a negative impact. Meanwhile, according to the results of quantile regression analysis to prove the psychic distance effect by OFDI size, the effects of CULD and INSD in the quartile (75%) to which Korea belongs were the same as the REM analysis results. In addition, GDP and EXPO had a positive effect, and PKM had a negative effect but EXPO had a positive effect. Therefore, FDI host countries need to establish differentiated strategies through quantile analysis while making continuous efforts to improve the system.

• The Journal of the Acoustical Society of Korea
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• v.27 no.3
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• pp.103-110
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• 2008

Strategically, the Patrol Killer Medium (PKM) ought to run at high speed that produces largely vibration by propeller, in a consequence, the vibration gradually deterioratescrews' working condition and increases the possibility of SONAR detection. In this paper, we propose the propeller damper, which is one of waysto reduce the vibration induced by the propeller, and simulate the ability of the damper numerically. The propeller damper was designed to apply to an isolated plate at the bottom flat board of ship which is directly affected by the fluctuating pressure. The dynamic pressure for the stern part of the PKM is calculated by using the DnV rule and the numerical analysis when the propeller damper applied or not, is performed with ANSYS at the isolated plate that simplified. From the analysis, the damping effect of the proposed propeller damper is confirmed and the reduction ratio for each compartment is estimated based on the experimental data in the PKM.

• BMB Reports
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• v.44 no.4
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• pp.279-284
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• 2011

The glutathione S-transferase (GST) system is useful for increasing protein solubility and purifying soluble GST fusion proteins. However, purifying half of the GST fusion proteins is still difficult, because they are virtually insoluble under non-denaturing conditions. To optimize a simple and rapid purification condition for GST-pyruvate kinase muscle 2 (GST-PKM2) protein, we used 1% sarkosyl for lysis and a 1 : 200 ratio of sarkosyl to Triton X-100 (S-T) for purification. We purified the GST-PKM2 protein with a high yield, approximately 5 mg/L culture, which was 33 times higher than that prepared using a conventional method. Notably, the GST-high-temperature requirement A2 (GST-HtrA2) protein, used as a model protein for functional activity, fully maintained its proteolytic activity, even when purified under our S-T condition. This method may be useful to apply to other biologically important proteins that become highly insoluble in the prokaryotic expression system.

• Korean Journal of Agricultural Science
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• v.37 no.2
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• pp.239-243
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• 2010

The objective of this study was to evaluate effects of supplementation of ${\beta}$-mannanase (CTCZYME$^{(R)}$, CTCBIO, Inc.) on feed intake, growth performance and fecal health of calves fed two levels (3% vs. 8%) of palm kernel meal (PKM). A total of nine Holstein calves were divided into three groups, and fed a conventional starter containing 3% PKM (CON), CON+0.1% CTCZYME$^{(R)}$ (TRT1), or a starter containing 8% PKM+0.1% CTCZYME$^{(R)}$ (TRT2). No clinical symptom of calves was observed through the trial. We did not find significant differences among the treatments on mean feed intake, growth performance, or fecal health during the four-week experimental period. Feed efficiency tended to be improved by adding CTCZYME$^{(R)}$ (0.46, 0.87 and 0.52 for CON, TRT1 and TRT2, respectively). Compared with CON (921 g/d and 786 g/d), TRT2 had lower feed intake (727 g/d) and average daily gain (ADG, 631 g/d) before weaning. However, feed intake (2300 g/d) and ADG (1012 g/d) were similar or even higher in TRT2 than CON (2269 g/d and 560 g/d) after weaning. This was probably due to the effect of a large amount of mannan-oligosaccharide released from PKM by ${\beta}$-mannanase. Salmonella was not detected any fecal samples. No significant difference was observed in the number of fecal E. coli or fecal properties including color, smell, and watery indexes among the treatments. We conclude that a calf starter containing 8% PKM with 0.1% CTCZYME$^{(R)}$ is comparable with a conventional starter in feed intake and growth performance of calf, which is beneficial in terms of reduction in feed cost.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2003.05a
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• pp.1150-1156
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• 2003

This paper suggests process knowledge management (PKM) which aims at lossless integration of business process management (BPM) and knowledge management (KM). To implement PKM, this paper suggests the concept of process knowledge and explores how to use them to extend the functionalities of knowledge management systems and process management systems by considering the lifecycle requirements of both knowledge and business processes. The framework and extended functionalities can provide a new corporate paradigm that combines the advantages of BPM and KM. Further, important corporate knowledge about business processes can be defined and managed in a single framework.

• Toxicological Research
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• v.32 no.1
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• pp.47-56
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• 2016

The identification of biomarkers for the early detection of acute kidney injury (AKI) is clinically important. Acute kidney injury (AKI) in critically ill patients is closely associated with increased morbidity and mortality. Conventional biomarkers, such as serum creatinine (SCr) and blood urea nitrogen (BUN), are frequently used to diagnose AKI. However, these biomarkers increase only after significant structural damage has occurred. Recent efforts have focused on identification and validation of new noninvasive biomarkers for the early detection of AKI, prior to extensive structural damage. Furthermore, AKI biomarkers can provide valuable insight into the molecular mechanisms of this complex and heterogeneous disease. Our previous study suggested that pyruvate kinase M2 (PKM2), which is excreted in the urine, is a sensitive biomarker for nephrotoxicity. To appropriately and optimally utilize PKM2 as a biomarker for AKI requires its complete characterization. This review highlights the major studies that have addressed the diagnostic and prognostic predictive power of biomarkers for AKI and assesses the potential usage of PKM2 as an early biomarker for AKI. We summarize the current state of knowledge regarding the role of biomarkers and the molecular and cellular mechanisms of AKI. This review will elucidate the biological basis of specific biomarkers that will contribute to improving the early detection and diagnosis of AKI.

• The KIPS Transactions:PartC
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• v.16C no.2
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• pp.257-266
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• 2009

Now a days, as increased the use of mobile units like a laptop computer and PDA, the demand for high speed internet service is increasing. On the other hand, PKMv2 which is provided from IEEE 802.16e cannot support fully on the security of high speed internet service. This paper proposes light-weight mutual authentication protocol which solved security problem of PKMv2 related to integrity of mobile node for transmission of safe high speed data of mobile node operating in mobile WiMAX environment. Proposed mutual authentication protocol increases the efficiency as the user in network can move in network safely without additional procedure of authentication between subscriber and base station after user's initial authentication. Also, the proposed mutual authentication protocol is safe from the security attack (the man-in-the-middle attack and reply attack) between subscriber and base station by generating a key adopt to PRF() function using random number and secret value in order to secure certification.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2011.06a
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• pp.801-802
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• 2011

• Asian-Australasian Journal of Animal Sciences
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• v.27 no.7
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• pp.946-950
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• 2014

Bacillus licheniformis was grown in minimal nutrient medium containing 1% (w/v) of distillers dried grain with soluble (DDGS), palm kernel meal (PKM), wheat bran (WB) or copra meal (CM), and the enzyme activity of endoglucanase, ${\beta}$-glucosidase, xylanase and reducing sugars was measured to investigate a possibility of using cost-effective agricultural residues in producing cellulolytic and hemicellulolytic enzymes. The CM gave the highest endoglucanase activity of 0.68 units/mL among added substrates at 48 h. CM yielded the highest titres of 0.58 units/ml of ${\beta}$-glucosidase, compared to 0.33, 0.23, and 0.16 units/mL by PKM, WB, and DDGS, respectively, at 72 h. Xylanase production was the highest (0.34 units/mL) when CM was added. The supernatant from fermentation of CM had the highest reducing sugars than other additional substrates at all intervals (0.10, 0.12, 0.10, and 0.11 mg/mL respectively). It is concluded that Bacillus licheniformis is capable of producing multiple cellulo- and hemicellololytic enzymes for bioethanol production using cost-effective agricultural residues, especially CM, as a sole nutrient source.

• Information and Communications Magazine
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• v.24 no.11
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• pp.5-13
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• 2007

광대역 무선 접속 표준을 관장하는 IEEE 802.16 워킹 그룹은 IEEE 802.16 표준을 2004년에 발표하였으며 이 IEEE 802.16 표준안에는 현재 WiMAX(Worldwide Interoperability for Microwave Access)라 불리는 고정 및 저속 이동 접속에 대한 광대역 무선 통신 지원 기술이 포함되어 있다. 특히 여러 기술 중 보안 관점에서 IEEE 802.16 표준은 MAC 계층 안에 PKM(Privacy Key Management)라고 불리는 Security Sub-layer를 가지고 있다. PKM은 PKMv1과 PKMv2로 구분되며, 먼저 PKMv1은 기본적인 인증 및 기밀성 기능을 제공하고 IEEE 802.16 표준에 기본적으로 적용되어있다. 하지만, IEEE 802.16 표준 이후 많은 연구들이 PKMv1의 보안성에 대하여 의문을 제기하였고 이에 따라 IEEE 802.16 표준안의 확장 개선안으로서 완전한 이동성을 바탕으로 하는 2005년 발표된 IEEE 802.16e 표준안에서는 향상된 보안 기능을 제공하는 PKMv2를 제공하며 기존 표준안의 부족한 점을 보완하기 위하여 시도하였다. 이러한 PKMv2는 EAP(Extensible Authentication Protocol) 인증, AES(Advanced Encryption Standard) 기반 기밀성 제공 알고리즘, CMAC/HMAC(Cipher/Hashed Message Authentication Code)을 사용한 메시지 인증 기능 제공 등 보다 다양한 보안 기능을 제공하였다. 그러나 IEEE 802.16e 표준안의 보안 기능은 SS(Subscriber Station)과 BS(Base Station)간의 통신구간 보안에 초점을 맞추어서 네트워크 도메인간의 보안 문제나 핸드오버시 보안과 같은 네트워크 구조적 보안 취약성을 여전히 가지고 있다. 하지만 표준안에서 정의하고 있는 SS와 BS 구간 보안 역시 완전한 솔루션을 제시하고 있지는 않다. 본 논문에서는 이러한 취약성을 고찰하고 그에 따른 대응방안을 제시하였다.