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Whitening Effect and Mechanism of Aerial Part of Pueraria lobata (갈만 추출물의 미백활성 및 기전 연구)

  • Kim, Da Eun;Hwang, Yeon Sil;Chang, Bo Yoon;Han, Ji Hye;Kim, Dae Sung;Kim, Hye Soo;Cho, Hyoung Kwon;Kim, Sung Yeon
    • Korean Journal of Pharmacognosy
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    • v.47 no.4
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    • pp.343-351
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    • 2016
  • The purpose of this study was to evaluate the whitening effect of aerial part of Pueraria lobata and mechanisms. Aerial part of Pueraria lobata, dose-dependently reduced the melanin content. Aerial part of Pueraria lobata, significantly decreased cellular tyrosinase activity, while there was not any effect on tyrosinase in cell-free conditions. To elucidate the mechanisms behind the aerial part of Pueraria lobata, treated melanogenesis regulation, the expressions of melanogensis related genes, proteins, and the activity of ${\alpha}-glucosidase$ were determined. Aerial part of Pueraria lobata, significantly inhibited gene and protein levels of MITF, tyrosinase and TRP-1. It suppressed the ${\alpha}-glucosidase$, leading to inhibition on the maturation of tyrosinase. Also aerial part of Pueraria lobata, was observed to have the high antioxidant activity. These results suggested that whitening effect of aerial part of Pueraria lobata, should be due to the down-regulation of MITF, tyrosinase and TRP-1 expression and the intercepting maturation of tyrosinase through suppressing ${\alpha}-glucosidase$. Another should be the high anti-oxidant activity. The findings show the possibility that aerial part of Pueraria lobata, can be used as a potential skin-whitening agent.

The Effect of White Rat's Growth Supplemented by Fermented Wheat Bran. (미생물에 의하여 영양가를 높인 밀기울이 흰쥐의 성장 발달에 미치는 영향)

  • 김숙희
    • Journal of the Korean Home Economics Association
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    • v.8 no.1
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    • pp.124-145
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    • 1970
  • The author carried out this study to research the biological value of the protein fermented wheat bran. This study mainly devided into two parts. First part includes seven subgroups composed of five rats and second part fourteen subgroups composed of six rats each. In the first part of this study forty weanling male rats, aged 40${\pm}$5 days were fed by fermented wheat bran diet for seven weeks. In second part of this study 90 male weanling rats were fed by rice and soybean diet supplemented by fermented wheat bran. In the first part of this study food consumption rate of fermented group showed higher than standard group but the former group is lower than the later in the body weight gains. In the second part of this study, rice groups showed same trend of the result of the first part, but soybean groups did not go along with the result of rice group. In regard to body nitrogen retention rate, fermented wheat diet group showed higher than the standard group in the first part of this study. In the second part of this study rice diet groups revealed same result as that of the first part of this study but soybean diet did not give the same result in this respect. There was no significant difference in organ weight in all experimental groups but devided by 100 gram of body weight, the reverse is true in compare with body weight gains. Hematological investigation did not show the significance in both experimental and standard groups of the first and the second studies. It is conclusion of this study that rice which is inferior to soybean in protein quality, increases the rate of supplementary effect by fermented wheat bran in all respects of this study.

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Ceramic Bottle Having Dual Structure (이중 내부구조를 갖는 도자기보틀)

  • Kim, Seok-Ho
    • The Journal of the Korea Contents Association
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    • v.8 no.4
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    • pp.92-99
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    • 2008
  • Most of existing Ceramic bottle has a problem because of the entrance facing the upper, and then having the entrance exposed in the outside. This study has made up for this problem and manufactured a bottle having dual structure. This bottle contains the contents being poured, has the containing part having the entrance in the lower part, multiple connecting passage hole connected with the water containing part in the upper, and the storage part, keeping contents, located in the circumference of the water containing part. The tail end of the entrance of the water containing part is located more upper than the lower part of a storage part, being at the bottom. This bottle has a dual structure of which the entrance faces the lower part. So, because of checking a foreign substance to be inflowed, restraining the diffusion of an alcohol ingredient, it is possible to have the custody of products, having alcohol element, and other contents for a long time. And then, the water containing part, through the connecting hole, always can pour the contents of a certain level in a cup or bowl. Accordingly, the purpose of this study is to make a convenient, a practicable bottle with having settled problems of customary know-how explained previously.

A Study on the Part Shrinkage in Injection Molded Annular Shaped Product for Glass Reinforced Polycarbonate (유리섬유 강화 폴리카보네이트의 환상형상부품 사출성형시 성형수축에 관한 연구)

  • Lee, Mina;Lyu, Min-Young
    • Elastomers and Composites
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    • v.48 no.4
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    • pp.300-305
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    • 2013
  • Part shrinkage in injection molding is inevitable phenomenon. Thus, it is necessary not only study on the reducing part shrinkage but characterization of part shrinkage. In this study, part shrinkage in injection molded 2.5 dimensional annular shaped specimens has been studied using glass fiber reinforced PC. Annular shaped specimens were designed with various sizes of outer diameter and thickness. Injection temperature, packing time and packing pressure were selected for operational conditions. Profile variations of outer and inner diameters of molded specimens for various operational conditions were investigated. Sizes of outer and inner diameters of injection molded specimens were smaller than the sizes of mold. Part shrinkage decreased as outer diameter and thickness increased. Part shrinkage showed anisotropic behavior and it depended upon gate location. Subsequently, molded specimens were not circular but oval in shape, and showed the largest shrinkage in the direction of gate. It was realized that the mold design such as gate design is important to control the shape of molded products.

Voluntary Choice of Part-time Work and Job Satisfaction (시간제근로에서 자발성과 일자리 만족)

  • Sung, Jaimie;Ahn, Joyup
    • Journal of Labour Economics
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    • v.30 no.1
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    • pp.109-137
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    • 2007
  • One of the key features of the Korean labor market is that, even though the central axis of employment has shifted from manufacturing sector to service sector, the ratio of part-time work is very low. Its major reasons are low wage rate, insufficient fringe benefits including social insurance, and deficient job security, even though part-time work has positive characteristics. This study examines whether part-time work would be a decent one and an alternative to full-time work by answering two questions: one is who chooses part-time work and another is whether part-time work is satisfactory. Analyses of 3,971 wage workers in the 8th wave of the Korea Labor and Income Panel Survey reveal that, as expected, part-time work is prevalent among the young, married women, and the old supporting the results from previous studies and that choosing part-time work on one's initiatives has a significant positive effect on job satisfaction for women while it is not for men. Form the result, it can be concluded that part-time work can be an appropriate alternative for full-time work if one chooses it voluntarily.

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Image Retrieval Using the Color Co-occurrence Histogram Describing the Size and Coherence of the Homogeneous Color Region (칼라 영역의 크기와 뭉침을 기술하는 칼라 동시발생 히스토그램을 이용한 영상검색)

  • An Myung-Seok;Cho Seok-Je
    • The KIPS Transactions:PartB
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    • v.13B no.3 s.106
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    • pp.275-282
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    • 2006
  • For the efficient image retrieval, the method has studied that uses color distribution and relations between pixels. This paper presents the color descriptor that stands high above the others in image retrieval capacity. It is based on color co-occurrence histogram that the diagonal part and the non-diagonal part are attached the weight and modified to energy of color co-occurrence histogram, and the number of bins with petty worth have little influence is curtailed. It's verified by analysis that the diagonal part carries size information of homogeneous color region and the non-diagonal part does information about the coherence of it, Moreover the non-diagonal part is more influential than diagonal part in survey of similarity between images. So, the non-diagonal part is attached more weight than the diagonal part as a result of the research. The experiments validate that the proposed descriptor shows better image retrieval performance when the weight for non-diagonal part is set to the value between 0.7 and 0.9.

Design of Face Recognition algorithm Using PCA&LDA combined for Data Pre-Processing and Polynomial-based RBF Neural Networks (PCA와 LDA를 결합한 데이터 전 처리와 다항식 기반 RBFNNs을 이용한 얼굴 인식 알고리즘 설계)

  • Oh, Sung-Kwun;Yoo, Sung-Hoon
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.61 no.5
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    • pp.744-752
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    • 2012
  • In this study, the Polynomial-based Radial Basis Function Neural Networks is proposed as an one of the recognition part of overall face recognition system that consists of two parts such as the preprocessing part and recognition part. The design methodology and procedure of the proposed pRBFNNs are presented to obtain the solution to high-dimensional pattern recognition problems. In data preprocessing part, Principal Component Analysis(PCA) which is generally used in face recognition, which is useful to express some classes using reduction, since it is effective to maintain the rate of recognition and to reduce the amount of data at the same time. However, because of there of the whole face image, it can not guarantee the detection rate about the change of viewpoint and whole image. Thus, to compensate for the defects, Linear Discriminant Analysis(LDA) is used to enhance the separation of different classes. In this paper, we combine the PCA&LDA algorithm and design the optimized pRBFNNs for recognition module. The proposed pRBFNNs architecture consists of three functional modules such as the condition part, the conclusion part, and the inference part as fuzzy rules formed in 'If-then' format. In the condition part of fuzzy rules, input space is partitioned with Fuzzy C-Means clustering. In the conclusion part of rules, the connection weight of pRBFNNs is represented as two kinds of polynomials such as constant, and linear. The coefficients of connection weight identified with back-propagation using gradient descent method. The output of the pRBFNNs model is obtained by fuzzy inference method in the inference part of fuzzy rules. The essential design parameters (including learning rate, momentum coefficient and fuzzification coefficient) of the networks are optimized by means of Differential Evolution. The proposed pRBFNNs are applied to face image(ex Yale, AT&T) datasets and then demonstrated from the viewpoint of the output performance and recognition rate.

A Phenomenological Study on Growth Experience of Youth with Part-time Jobs (아르바이트 청소년의 성장경험에 관한 현상학적 연구)

  • Koo, Seung-Shin
    • The Journal of the Korea Contents Association
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    • v.17 no.10
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    • pp.406-419
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    • 2017
  • This study is to explore the essence and meaning of part-time job experience, in particular, to deduce growth experience through part-time jobs. This study is based on time-experience of phenomenological research method developed by the van Manen. For this research, the research data was collected by reviewing high school student part timer in Gyeonggi-do, those who had experience of average of two-year part time work or currently at work, and by undertaking in-depth interviews with seven of them from the March to April of 2017 with the agreements of the participants of this study. Time-experiences, i.e. part-time job experiences of youths, can be arranged as the following subjects. 'the feeling necessity part-time job and seeking it', 'adapting hard life of part-time', growth-experiencing through part-time work..The necessities for part-time job are feeling up consumption needs, aidsing domestic economy, pursuing independence, social and leisure life, self growth and preparing for the future. Adapting of part-time jobs are mastering, enduring, skillfuling work related to work adatation, and enduring ostracizing of old members, stopping and lasting, building bonds related to relationship adaptation. Growth-experiencing through part-time work are formig rational management for money, mental growth, preparing for the future. Based on these findings, the suggestion and limitation of the study were presented.

MORPHOLOGY OF UROHYAL BONES OF PLEURONECTIDAE FISHES IN KOREAN WATERS (한국산 가자미과 어류의 미설골의 형태에 관하여)

  • KIM Yong Uk
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.5 no.4
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    • pp.121-127
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    • 1972
  • The present paper deals with the results of the comparative morphology on the urohyal bones on the right-eye flounders, pleuronectidae fishes in Korean waters. The results obtained are as follows : 1. The position of the tip of sciatic part is quite different depending on the genera and species of the fishes. The sciatic part of the genera, Platichthys and Cleisthenes, is very short extending to the middle portion of the main part. In the fishes of Eopsetta and Tanakius, it is also very short extending to the anterior 1/3 of the distance from the tip of main part. The fishes of Verasper and Dexistes have a short sciatic part which extends toward the posterior 1/4 of the distance from the tip of main part. The fishes Of Limanda, Clidoderma, Glyptecephalus and Microstomus have a long sciatic part which extends as long as the main part. However, those of Kareius and Pleuronichthys have a very long sciatic part extending twice long as the main part. The tip of sciatic part of the fishes belonging to Eopsetta, Verasper, Limanda, Platichthys, Tanakius and Glyptocephalus is a truncate form. It is pointed upward in the fishes of Kareius, Pleuronichthys, Clidoderma and Microstomus, but pointed forward in Cleisthenes and Dexistes. 2. The size and form of the cardiac apophysis vary with the developmental grades of the urohyal bone. The fishes of Eopsetta, Verasper, Platichthys, Tanakius, Kareius and Dexistes possess relatively large apophyses and those of Pleuronichthys and Clidoderma have small apophyses. Intermediate size of the apophysis is found in the fishes of Limanda, Microstomus and Cleisthenes. A long and barlike apophysis is found in Glyptocephalus. Three kinds of the cardiac. apophysis are found in the fishes examined, i. e., lateral wing in Eopsette, Verasper, Limanda, Platichthys, Tanakius, Glyptocephalus, Kareius, Pleuronichthys and Clidoderma, pointed forward in Microstomus and Cleisthenes, and truncate with a well-developed inner ridge type in Dexistes. 3. The angle of the main part and sciatic part varies from 30 to 60 degrees in the fishes studied except for the fishes of Pleuronichthys, Clidoderma and Microstomus which show a semi-elliptical form.

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Dimensional change of micro forged part on precision cold forging (미세성형품의 정밀 냉간단조시 치수변화 분석)

  • Lee, M.W.;Lee, Y.S.;Lee, J.H.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2008.10a
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    • pp.254-258
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    • 2008
  • Dimensional accuracy is very important quality in micro forged part, especially on forged part. Dimension of forged part is changed continuously during forging process. Loading, unloading and ejecting stage affects dimensional of the forged tool. The elasto-plastic material model for billet and elastic model for die were used to analyze these changes. At same time, the calculated results were compared and analyzed by the experiment on same conditions. From the experimental and analytical studies, we can calculated the amount of difference between die and forged part, that is 0.49% based on the die dimension. The dimensional change is smaller than that of general sized-forged part,0.6%.

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