• ALGAE
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• 제29권1호
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• pp.27-34
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• 2014

Availability of nutrients is known to influence marine primary production; and it is of general interest to see how nutrient limitation mediates phytoplankton responses to solar ultraviolet radiation (UVR, 280-400 nm). The red tide diatom Skeletonema costatum was cultured under nitrate (N)-limited and N-replete conditions and exposed to different solar irradiation treatments with or without UV-A (315-400 nm) and UV-B (280-315 nm) radiation. Its photochemical quantum yield decreased by 13.6% in N-limited cells as compared to that in N-replete ones under photosynthetically active radiation (PAR)-alone treatment, and the presence of UV-A or UV-B decreased the yield further by 2.8 and 3.1%, respectively. The non-photochemical quenching (NPQ), when the cells were exposed to stressful light condition, was higher in N-limited than in N-replete grown cells by 180% under PAR alone, by 204% under PAR + UV-A and by 76% under PAR + UV-A + UV-B treatments. Our results indicate that the N limitation exacerbates the UVR effects on the S. costatum photosynthetic performance and stimulate its NPQ.

• 한국음향학회지
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• 제14권1호
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• pp.40-47
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• 1995

본 논문은 redundancy를 제거함으로 해서 데이타의 축약을 할 수 있는 새로운 방법론 즉, 병렬 컴퓨터인 MasPar 머쉰에 적합한 새로운 데이타 구조를 제시하고자 하는데 그 주된 목적이 있다. 이것을 실제로 구현한 결과, 본 논문에 제시된 방법인 PDOCM (Parallel Dynamic Octal Compact Mapping)은 기존의 방법중 가장 효율이 좋은 것으로 나타난 Huffman 코드와 비교할때는 평균적으로 $30\%$정도, bit-mapping방법과 비교할때는 평균적으로 $40\%$ 정도의 우수성을 보였다. 그리고 10 백만개의 영문자를 이용해서 MasPar 기계에서 64개의 프로세서를 이용하여 구현시킨 결과 54.188의 가속화율을 얻으므로서 우수한 방법임을 알 수가 있었다.

• 응용통계연구
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• 제29권1호
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• pp.133-144
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• 2016

본 논문에서는 주기적 자기회귀(periodic autoregressive) 모형에서 모수의 수를 줄이기 위한 모수 절약 주기적 자기회귀 모형을 연구하였다. 제안된 모수 절약 모형은 실증분석에서 실업률을 이용하여 기존의 계절 시계열 모형과 비교를 통하여 그 성능을 평가하였다. 모수 절약 구조를 부여하기 위하여 계절성에서 공통된 패턴을 찾아내는 방법을 사용하였으며 기존 주기적 자기회귀 모형과의 통계적 차이 유무는 LR 검정을 통해 확인하였다. 그 결과, 중장기적으로 주기적 자기회귀 모형이 기존의 계절시계열 모형보다 우수한 예측성능을 보였으며, 특히 모수 절약 주기적 자기 회귀 모형의 사용은 기존의 주기적 자기회귀 모형보다 우수한 예측성능을 나타내는 것을 확인하였다.

• 한국약용작물학회지
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• 제13권6호
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• pp.245-249
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• 2005

신이는 전통적으로 비염 등의 치료에 사용되어 왔는데, 신이 에탄올 추출물은 그람 양성균인 Staphylococcus aureus 그람 음성균인 Pseudomonas fluorescens균 및 곰팡이균인 Aspergillus niger에 대하여 모두 항균활성을 보였으며, proteinase로 활성화된 receptor-2에 의한 흰쥐 뒷발바닥 부종모델에서 신이 에탄올 추출물을 경구투여한 경우 typsin이나 $tc-NH_2$로 유발된 발바닥 부종, 혈관투과성, myoloperoxidase 활성도에서 유의성 있는 억제율을 보여 항염증 활성이 뚜렷함을 나타냈다.

• Natural Product Sciences
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• 제13권2호
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• pp.169-173
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• 2007

Luteolin is a major flavonoid of Lonicera japonica and has anti-inflammatory effect. The activation of proteinase-activated receptor (PAR)-2 and -4 by trypsin appears to play a role in inflammation, In the present study, we examined the inhibitory effects of luteolin on activation of trypsin-induced human leukemic mast cells (HMC-1). HMC-1 cells were stimulated with trypsin, PAR-2 and PAR-4 agonist, in the presence or absence of luteolin. The level of TNF-${\alpha}$ secretion was measured by enzyme-linked immunosorbent assay (ELISA). The expression of tryptase and phosphorylated-extracellular signal-regulated kinase (ERK) were assessed by Westem blot analysis. Moreover, trypsin activity was measured by the substrate Bz-DL-Arg-p-nitroanilide (BAPNA). TNF-${\alpha}$ secretion and Tryptase expression in trypsin-stimulated HMC-1 cells were markedly inhibited by pretreatment of luteolin. Furthermore, the pretreatment of luteolin resulted in the reduction of ERK phosphorylation and trypsin activity. These results suggest that luteolin might has the inhibitory effects on the PAR-2 and -4-dependent inflammation.

• Nuclear Engineering and Technology
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• 제49권5호
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• pp.905-913
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• 2017

Advanced reactor designs often feature longer operating cycles between refueling and new concepts of operation beyond traditional baseload electricity production. Owing to this increased complexity, traditional proportional-integral control may not be sufficient across all potential operating regimes. The prototypical advanced reactor (PAR) design features two independent reactor modules, each connected to a single dedicated steam generator that feeds a common balance of plant for electricity generation and process heat applications. In the current research, the PAR is expected to operate in a load-following manner to produce electricity to meet grid demand over a 24-hour period. Over the operational lifetime of the PAR system, primary and intermediate sodium pumps are expected to degrade in performance. The independent operation of the two reactor modules in the PAR may allow the system to continue operating under degraded pump performance by shifting the power production between reactor modules in order to meet overall load demands. This paper proposes a Takagi-Sugeno (T-S) fuzzy logic-based power distribution system. Two T-S fuzzy power distribution controllers have been designed and tested. Simulation shows that the devised T-S fuzzy controllers provide improved performance over traditional controls during daily load-following operation under different levels of pump degradation.

• Journal of Microbiology and Biotechnology
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• 제15권6호
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• pp.1359-1367
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• 2005

The gene encoding Pyrobaculum arsenaticum DNA polymerase (Par DNA polymerase) was cloned and sequenced. The gene consists of 2,361 bp coding for a protein with 786 amino acid residues. The deduced amino acid sequence of Par DNA polymerase showed a high similarity to archaeal family B-type DNA polymerases (Group I), and contained all of the motifs conserved in the family B-type DNA polymerases for $3'{\rightarrow}5'$ exonuclease and polymerase activities. The Par DNA polymerase gene was expressed under the control of the T7lac promoter on the expression vector pET-22b(+) in Escherichia coli BL21-CodonPlus(DE3)-RP. The expressed enzyme was purified by heat treatment, and Cibacron blue 3GA and $Hirap^{TM}$ Heparin HP column chromatographies. The optimum pH of the purified enzyme was 7.5. The enzyme activity was activated by divalent cations, and was inhibited by EDTA and monovalent cations. The half-life of the enzyme at $95^{\circ}C$ was 6 h. Par DNA polymerase possessed associated $3'{\rightarrow}5'$ proofreading exonuclease activity, which is consistent with its deduced amino acid sequence. PCR experiment with Par DNA polymerase showed an amplified product, indicating that this enzyme might be useful in DNA amplification and PCR-based applications.

• 한국수산과학회지
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• 제47권3호
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• pp.247-254
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• 2014

To investigate the acquisition of quinolone resistance, we examined mutations in the quinolone resistance-determining region (QRDR) of type II topoisomerase genes in ciprofloxacin (CIP)-resistant clinical isolates and in vitro mutants of Streptococcus parauberis. The CIP-resistant clinical isolates had one base change responsible for a Ser-79${\rightarrow}$Thr in the QRDR of parC. However, the CIP-resistant in vitro mutants had an altered QRDR of parC (Ser-79${\rightarrow}$Ile) that differed from that of the isolates. None of the CIP-resistant S. parauberis clinical isolates or in vitro mutants exhibited amino acid changes in gyrA or gyrB. However, even though involvement in the increased resistance was not clear, an Arg-449${\rightarrow}$Ser mutation outside of the QRDR of parE was detected in CIP-resistant mutant 2P1. These results suggest that the topoisomerase IV gene, parC (and possibly parE, as well), is the primary ciprofloxacin target in S. parauberis. Additionally we established a high-resolution melting (HRM) assay capable of detecting the dominant mutation in four type II topoisomerase genes conferring ciprofloxacin resistance. These rapid and reliable assays may provide a convenient method of surveillance for genetic mutations conferring antibiotic resistance.

• 한국대기환경학회지
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• 제28권1호
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• pp.77-85
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• 2012

In this study, emission rates (ER) of biogenic volatile organic compounds (BVOCs) were measured by varying levels of photosynthetically active radiation (PAR). An appropriate plan for ozone reduction according to increasing ecology area ratio in future metropolitan areas was suggested. Several trees were selected as representative tree species in urban areas. Emission rates and composition ratios of monoterpene and isoprene emitted from these trees were estimated and compared. As a result, it was found that emission rates of BVOCs were considerably different depending on tree species. Especially, BVOCs emitted from Platanus orientalis and Quercus mongolica could significantly affect ozone increase in the metropolitan area, because the emission rates were several thousands to ten thousand times higher than those emitted from Zelkova serrata and Prunus serrulata. Furthermore, it was observed that emission rates of BVOCs by species increased maximum up to 10 times when PAR, which has close relations with temperature, rose. It was concluded that tree species such as Zelkova serrata et al., was appropriate for metropolitan areas since the species has low ozone potential and good landscape. Suppose this type of trees are planted on purpose in the urban areas, better ambient air quality will be promised in the future.

• 한국통신학회논문지
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• 제32권12C호
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• pp.1175-1187
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• 2007

이동통신 기지국 시스템에서 송신 신호의 PAR 성능을 (peak-to-average power ratio) 개선함으로써 범용 전력 증폭기의 사용이 가능하게 되며, 이로 인해 전체적인 기지국 비용의 절감을 기대할 수 있다. 일반적으로 PAR 값을 줄임으로 인해 기지국 송신신호의 인근 대역 간섭 제한 성능을 나타내는 ACLR이나 (adjacent channel leakage ratio) 품질을 나타내는 EVM이나 (error vector magnitude) PCDE 성능의 (peak code domain error) 열화를 발생시킨다. 본 논문에서 이러한 문제점을 해결하기 위하여 필터링 기반의 CFR 방식인 (crest factor reduction) FDCFR 알고리즘을 (filter-dependent CFR) 소개하며, 히스토그램 기반 코드 영역 보상(HBWCDC; histogram based waterfilling code domain compensation)기법을 제안한다. 본 논문에서 제안한 CFR 알고리즘은 PAR 감소뿐만 아니라 앞서 언급한 ACLR, EVM 및 PCDE등의 성능 열화를 방지한다.