• Title/Summary/Keyword: PA12

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Effect of slag and bentonite on shear strength parameters of sandy soil

  • Sabbar, Ayad Salih;Chegenizadeh, Amin;Nikraz, Hamid
    • Geomechanics and Engineering
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    • v.15 no.1
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    • pp.659-668
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    • 2018
  • A series of direct shear tests were implemented on three different types of specimens (i.e., clean Perth sand, sand containing 10, 20 and 30% bentonite, sand containing 1, 3 and 5% slag, and sand containing 10, 20 and 30% bentonite with increasing percentages of added slag (1%, 3% and 5%). This paper focuses on the shear stress characteristics of clean sand and sand mixtures. The samples were tested under different three normal stresses (100, 150 and 200 kPa) and three curing periods of no curing time, 7 and 14 days. It was observed that the shear stresses of clean sand and mixtures were increased with increasing normal stresses. In addition, the use of slag has improved the shear strength of the sand-slag mixtures; the shear stresses rose from 128.642 kPa in the clean sand at normal stress of 200 kPa to 146.89 kPa, 154 kPa and 161.14 kPa when sand was mixed with 1%, 3% and 5% slag respectively and tested at the same normal stress. Internal friction angle increased from $32.74^{\circ}$ in the clean sand to $34.87^{\circ}$, $37.12^{\circ}$ and $39.4^{\circ}$ when sand was mixed with 1%, 3% and 5% slag respectively and tested at 100, 150, and 200 kPa normal stresses. The cohesion of sand-bentonite mixtures increased from 3.34 kPa in 10% bentonite to 22.9 kPa, 70.6 kPa when sand was mixed with 20% and 30% bentonite respectively. All the mixtures of clean sand, different bentonite and slag contents showed different behaviour; some mixtures exhibited shear stress more than clean sand whereas others showed less than clean sand. The internal friction angle increased, and cohesion decreased with increasing curing time.

Inhibitory effects of Sargassum horneri extract against endoplasmic reticulum stress in HepG2 cells (괭생이 모자반 추출물의 소포체 스트레스 억제 효능)

  • Park, Sora;Thomas, Shalom Sara;Cha, Youn-Soo;Kim, Kyung-Ah
    • Journal of Nutrition and Health
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    • v.53 no.6
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    • pp.583-595
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    • 2020
  • Purpose: This study examined the effects of Sargassum horneri extracts on palmitic acid (PA)-induced endoplasmic reticulum (ER) stress in HepG2 cells. Methods: HepG2 cells were treated with varying concentrations of S. horneri extract or PA, and the cell viability was measured by water soluble tetrazolium salts analysis. The effective induction of ER stress and the effects of S. horneri were investigated through an examination of the ER stress-related genes, such as activating transcription factor 4 (ATF4), X-box binding protein (XBP1s), C/EBP homologous protein (CHOP), and 78-kDa glucose-regulated protein (GRP78) by quantitative reverse transcription polymerase chain reaction. The expression and activation levels of unfolded protein response (UPR) associated proteins, such as inositol-requiring enzyme-1α (IRE1α), eukaryotic translation initiation factor 2 alpha submit (eIF2α), and CHOP were examined by western blot analysis. Results: The treatment with PA increased the expression of UPR associated genes significantly and induced ER stress in a 12-hour treatment. Subsequent treatment with S. horneri reduced mRNA expression of ATF4, GRP78, and XBP1s. In addition, the protein levels of phosphate (p)-IRE1α, p-elF2α, and CHOP were also reduced by a treatment with S. horneri. An analysis of sirtuin (SIRT) mRNA expression in the S. horneri and PA-treated HepG2 cells showed that S. horneri increased the levels of SIRT2, SIRT6, and SIRT7, which indicates a possible role in reducing the expression of ER stress-related genes. Conclusion: These data indicate that S. horneri can exert an inhibitory effect on ER stress caused by PA and highlight its potential as an agent for managing various ER stress-related diseases.

Effects of Peroxisome Proliferator-Activated $Receptor-{\gamma}2$ Pro12Ala Polymorphism on Body Fat Distribution in Female Korean Subjects (Peroxisome Proliferator-Activated $Receptor-{\gamma}$ 2 $(PPAR{\gamma}2)$ Pro12Ala (P12A) 유전자 다형성이 한국여성의 체지방분포에 미치는 영향)

  • Kim, Kil-Soo;Choi, Sun-Mi;Yang, Hyun-Sung;Yoon, Yoo-Sik;Shin, Seun-Uoo
    • Journal of Korean Medicine for Obesity Research
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    • v.4 no.1
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    • pp.1-11
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    • 2004
  • Objectives: The effects of peroxisome proliferator-activated receptor ${\gamma}2\;(PPAR{\gamma}2)$ Pro12Ala (P12A) polymorphism on body mass index (BMI) and type 2 diabetes are well documented; however, until now, only a few studies have evaluated the effects of this polymorphism on body fat distribution. This study was conducted to elucidate the effects of this polymorphism on computed tomography (CT)-measured body fat distribution and other obesity-related parameters in Korean female subjects. Methods & Results: The frequencies of $PPAR{\gamma}2$ genotypes were: PP type, 93.0%; PA type, 6.8%; and AA type, 0.2%. The frequency of the A allele was 0.035. Body weight (P .012), BMI (P .012), and waist-to-hip ratio (WHR) (P .001) were significantly higher in subjects with PA/AA compared with subjects with PP. When body composition was analyzed by bioimpedance analysis, lean body mass and body water content were similar between the 2 groups. However, body fat mass (P .003) and body fat percent (P .025) were significantly higher in subjects with PA/AA compared with subjects with PP. Among overweight subjects with BMI of greater than 25, PA/AA was associated with significantly higher abdominal subcutaneous fat (P .000), abdominal visceral fat (P .031), and subcutaneous upper and lower thigh adipose tissue (P .010 and .013). However, among lean subjects with BMI of less than 25, no significant differences associated with $PPAR{\gamma}2$ genotype were found, suggesting that the fat-accumulating effects of the PA/AA genotype were evident only among overweight subjects, but not among lean subjects. When serum lipid profiles, glucose, and liver function indicators were compared among overweight subjects, no significant difference associated with $PPAR{\gamma}2$ genotype was found. Changes in body weight, BMI, WHR, and body fat mass were measured among overweight subjects who finished a 1-month weight lose program of a hypocaloric diet and exercise; no significant differences associated with $PPAR{\gamma}2$ genotype were found. Conclusions: The results of this study suggest that the $PPAR{\gamma}2$ PA/AA genotype is associated with increased subcutaneous and visceral fat areas in overweight Korean female subjects, but does not significantly affect serum biochemical parameters and outcomes of weight loss programs.

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Estimation of moisture maximizing rate considering an orographic property : Typhoon Rusa case in Gangneung region (지형적 특성을 고려한 강릉지역 태풍 루사의 수분최대화비 산정)

  • Kim, Moon-Hyun;Lee, Hye-Ran;Im, Eun-Soon;Kwon, Won-Tae
    • Proceedings of the Korea Water Resources Association Conference
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    • 2006.05a
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    • pp.1483-1487
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    • 2006
  • 본 연구에서는 2002년 태풍 루사(RUSA) 기간에 대한 강릉지역의 수분최대화비를 그 지역의 지형적인 특성을 고려하여 산정하였다. 수분최대화비는 최대가능강수(Probable Maximum Precipitation, 이하 PMP)를 추정하는데 가장 중요한 요소로써 최대 12시간 지속 1000 hPa 이슬점과 대표 12시간 지속 1000 hPa 이슬점에 따른 가강수량의 비로 계산된다. 각각의 이슬점을 결정하는 방법으로, 대표 12시간 지속 이슬점은 수분 유입지역을 파악함으로써 계산되는데, 이 유입지역은 지상일기도, 지표 풍향, 850 hPa 수분속, 유선장등을 고려하여 선정되었다. 또한 최대 12시간 지속 이슬점은 과거 42년간(1961년${\sim}$2002년)의 강릉지역 이슬점 온도 자료를 통해 방재연구소에서 제공하는 FARD2002 통계프로그램을 이용하여 구하였다. 이 프로그램에서 확률분포형으로는 Extreme TypeⅠ(Gumbel distribution)을 선정하였고 매개변수 추정방법으로 모멘트법을 사용하여 유의수준 10%에서 재현기간 50년 빈도 분석을 통해 이슬점 온도를 구하였다. 본 연구에서는 이와 같은 과정을 통해 재 추정된 수분최대화비와 기존에 제시된 호우전이비 및 DAD(Depth-Area-Duration) 분석결과를 이용하여 강릉호우의 소유역$(3.76km^2)$에 대한 PMP를 산정하고 기존 결과와의 차이점을 제시하였다.

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Implementation of Local Distribution Audio System Based on AoIP (AoIP 기반 지역분산형 오디오시스템의 구현)

  • Kang, Min-Soo;Lee, Sang-Wook;Park, Yeoun-Sik
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.12
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    • pp.2165-2170
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    • 2008
  • In this parer, it is implemented a Local distribution Audio System, based on AoIP(Audio over Internet Protocol) of a part of TCP/IP Network which belongs to Internet transmission technology. The system is controlled based on SNMP(Simple Network Management Protocol) and it is transferred to UDP as packet after changing from Analog audio sources to Digital audio sources. The implemented Local distribution Audio System have presented practical possibilities in PA system transmitting various audio sources to several areas, dispersedly and using multichannel audio like Home theaters in the limelight, recently.

A Study on the Waterproofing Performance of Waterproofing Methods for PHC-W Earth Retaining Wall Based on Pressure Chamber Test (PHC-W 흙막이 공법의 차수방안에 관한 차수성능확인을 위한 모형 압력 수조 실험 연구)

  • Choi, Yongkyu;Johannes, Jeanette Odelia;Yun, Daehee;Kim, Chae min;Jeon, Byeong Han
    • Journal of the Korean Geotechnical Society
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    • v.33 no.12
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    • pp.115-125
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    • 2017
  • PHC-W earth retaining wall could be constructed continuously. Various retaining wall methods such as C.I.P. etc. method require separate waterproof method. However, the PHC-W retaining wall method prevents leakage of groundwater by inserting a waterproofing material at connection part between 2 PHC piles. In this study, the experimental study on 3 waterproofing method for PHC-W retaining wall was conducted at the model pressure chamber. In the method using textile with 1-liquid type and 2-liquid type urethane, rapid leak occurred at the pressure of 120 kPa and 140 kPa or more. In the method of textile with grouting, rapid leak occurred at the pressure of 120 kPa or more, however, in this method, the rapid leakage happened at the top part and the bottom part reinforced with urethane.

Study on Risk-based Satellite Product Assurance and Tailoring (리스크 기반의 위성 제품보증 및 테일러링 분석)

  • Song, Sua;Chang, Young-Keun
    • Journal of Aerospace System Engineering
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    • v.12 no.5
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    • pp.76-88
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    • 2018
  • Space agencies such as NASA, ESA, and the US military provide guidelines and standards for PA(product assurance) requirements and plans. In recent years, major satellite manufacturers around the world have been mitigating PA requirements and processes by tailoring. PA tailoring has been implemented to improve the cost and schedule efficiency. PA tailoring can be accomplished based on various factors such as mission, classification of mission risk, complexity, development cost, life cycle, etc. In this study, PA tasks according to the mission risk classification proposed by NASA are investigated, and the tailoring method is suggested for the optimization of the development cost and schedule. In particular, the classification of mission risk for the satellites under development or operation in Korea is performed, and PA characteristics in accordance with mission risk are analyzed.

Design and Implementation of Efficient PA Technology for Mobile PST (모바일 PST를 위한 효율적 PA 기법 설계 및 구현)

  • Shim, Jae-Sung;Park, Seok-Cheon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.12
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    • pp.3049-3054
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    • 2014
  • PST stands for the Premium Sales Tool for Product Consulting is customized product catalog system. In other words, the product classification categories of content for consulting and sales to customers by providing useful information for the maximization of an overall system. These problems with mobility and flexibility of updating the solution to integrate mobile with mobile devices, but high-performance high-resolutions era content data continuously, but still it is difficult to handle. In this paper, to solve this problem, depending on the user's gesture by allowing periodic allocation and release of a problem for load generation enhanced by improving the PST system has been designed and implemented. Implementation was a result of the test the performance of the system, that PA system that has been provided by the traditional DA system show the allocation and the average 78% of the rate of decrease the load is released in the frequency of page, CPU utilization was reduced an average 72% I was confirmed.

A Fully-Integrated Low Power K-band Radar Transceiver in 130nm CMOS Technology

  • Kim, Seong-Kyun;Cui, Chenglin;Kim, Byung-Sung;Kim, SoYoung
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.12 no.4
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    • pp.426-432
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    • 2012
  • A fully-integrated low power K-band radar transceiver in 130 nm CMOS process is presented. It consists of a low-noise amplifier (LNA), a down-conversion mixer, a power amplifier (PA), and a frequency synthesizer with injection locked buffer for driving mixer and PA. The receiver front-end provides a conversion gain of 19 dB. The LNA achieves a power gain of 15 dB and noise figure of 5.4 dB, and the PA has an output power of 9 dBm. The phase noise of VCO is -90 dBc/Hz at 1-MHz offset. The total dc power dissipation of the transceiver is 142 mW and the size of the chip is only $1.2{\times}1.4mm^2$.

Compatibility Studies of Blends of Engineering polymers and Thermotropic Liquid Crystalline Polymers (엔지니어링 고분자와 열방성 액정고분자 블렌드의 상용성에 관한연구)

  • 전용성
    • The Korean Journal of Rheology
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    • v.9 no.2
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    • pp.53-59
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    • 1997
  • 열방성 액정고분자(LCP)와 polycarbonate(PC) poly(ether imide) (PEI) poly(PEEK), polysulfone(PSF), 그리고 polyarylsulfone(PAS)과의 블렌드에 대한 상용성을 연구하였다. 제조된 블렌드의 상거동에서 액정고분자가 PC-, PEI-, PEEK-, PSF-, 그리고 PAS-rich 상 에 녹아 들어가는 양이 PC, PEI, PEEK, PSF, 그리고 PAS가 액정 고분자 -rich상에 녹아들 어가는 양보다 많음을 알수 있었다. 측정된 블렌드의 유리전이온도 결과로부터 PC, PEI, PEEK와 액정고분자 사이의 상용성이 PSF, PAS와 액정 고분자 사이의 상용성에 비하여 더 좋음을 알수 있었다. 액정 고분자의 이방성을 고려하여 고분자-고분자 상호작용계수($\chi$12)를 결정하였으며, PC, PEI, PEEK, PSF, 그리고 PAS를 포함한 액정 고분자 블렌드에서 $\chi$12는 0.078-0.183으로 나타났다.

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