• 대한디지털의료영상학회논문지
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• 제12권2호
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• pp.119-125
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• 2010

In order to demonstrate the value of long-distance radiography, we have studied how distance affects images in chest frontal radiography and compared short-distance and long-distance images in chest lateral radiography. Cardiothoracic ratio(CTR %) of 50 patients with no disease in the chest(10 each at the age of 20~60) were evaluated in Supine AP(100 cm), Sitting AP(100 cm), Sitting AP(180 cm), and Erect PA(180 cm). In lateral radiography, we evaluated and compared left lateral radiography(100 cm and 180 cm) of the patients based on the horizontal maximum of the heart. The average value of CTR(%) were 0.48 in Erect PA(180 cm), 0.52 in Supine AP(100 cm), 0.50 in Sitting AP(100 cm), 0.49 in Sitting AP(180 cm), which were Supine AP(100 cm) > Sitting AP(100 cm) > Sitting AP(180 cm) > Erect PA(180 cm). The average value of Maximum transverse diameter of left of the cardiac(MLD), which showed how much axis of spine was slanted to the left, was 90.67 mm in Erect PA(180 cm), 103.92 mm in Supine AP(100 cm), 93.54 mm in Sitting(100 cm), 89.84 mm in Sitting AP(180 cm), 58.11 mm in the minimum value and 118.79 mm in the maximum value. The average value of Maximum transverse diameter of right side of the cardiac(MRD), which suggested how much axis of spine was slanted to the right, was 47.18 mm in Erect PA(180 cm), 48.12 mm in Supine AP(100 cm), 44.98 mm in Sitting AP(180 cm), and the minimum value 26.84 mm and the maximum value 65.30 mm. There was no standard method to calculate; therefore, the horizontal maximum of the heart was used for lateral radiography. The average value was 121.07 mm in 100 cm and 109.76 mm in 180 cm. Sitting AP(180 cm) among the types was closest to C-PA(180 cm). As a result, during C-AP radiography, long-distance radiography lessened shadow of the heart more than that of short distance, Sitting position more than Supine position.

• 기본간호학회지
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• 제7권3호
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• pp.355-365
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• 2000

The purpose of this research was to find out the effect of chest physiotherapy on the amount of tracheal secretion and $PaO_2$. After changing position of the neurosurgical patients who had tracheostomy cannula, experimental treatments were applied as bellows, manual chest percussion on groupI, chest percussion and manual chest vibration on groupII, chest percussion and mechanical chest vibration on groupIII were done. After these trials, we have analyzed the efficacy of each procedures comparing the group differences in the quantity of tracheal secretion and $PaO_2$. Target samples were sixty patients aged between 20 to 60 who have tracheostomy state and decreased consciousness status that were admitted in NICU of a university hospital from June 1 to August 31, 1999. They assigned randomly into three experimental groups. To compare the effect of each interventions, tracheal secretion quantify was measured and $PaO_2$ was analyzed via arterial blood gas analyzer. The data were analyzed by ANCOVA of 5% significance level using SPSS P/C program. The results were as bellows. 1) The first hypothesis 'There is a difference In the quantify of the secretion among GroupI, GroupII and GroupIII' was accepted.(F=29.27, p=0.00) 2) The second hypothesis 'There is a difference in $PaO_2$ among GroupI, GroupII and GroupIII' was rejected.(F=1.71, p=0.19) From this study results, positional change and manual chest vibration including chest percussion were the most effective treatment to get maximum amount of tracheal secretion and it was confirmed that mechanical chest vibration also made much better effect than sole chest percussion method. Therefore, we concluded that the mechanical or manual chest vibration with chest percussion is more effective respiratory care method than the sole chest percussion.

• 한국산학기술학회논문지
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• 제20권1호
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• pp.284-289
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• 2019

접이식 대피통로는 철도터널 및 대공간 화재시 임시 피난로를 확보하기 위한 피난지원 시스템으로 화재시 구조물 상부에 거치되어 있던 차연 스크린이 펼쳐지며 피난로를 확보하는 시스템이다. 차연 스크린은 적절한 내화성능을 갖추어야 될 뿐 아니라 밀폐성을 확보하여 외부의 연기를 최대한 막을 수 있는 시스템이 요구된다. 이를 위해 접이식 대피통로 시스템에는 피난로 내부에 양압 조건을 유지해 주기 위한 제연설비가 필요하며, 제연 설비의 설계 및 용량 산정을 위해서는 화원에서 거리별 온도 분포 및 압력 해석이 필요하다. 본 연구에서는 신형전동차의 화재 현상을 모사하여 터널 길이방향별 온도 및 압력 분포를 해석하였다. 차연 스크린 설치 위치에서는 길이방향으로 20미터 이상일 경우에는 차연 스크린 내열온도인 200도를 넘지 않는 것으로 해석되었으며, 압력 또한 거리 증가에 따라 감소하며, 최대 14 Pa, 평균 6 Pa 정도를 보이는 것으로 해석되었다. 또한 상부 보단 하부에서의 압력이 낮기 때문에 실제 양압조건은 이보다 낮을 것으로 보인다. 따라서 접이식 대피통로 설치를 위해서는 차연 스크린내 양압조건을 6 Pa 내외로 유지할 수 있는 제연설비가 필요할 것으로 예측된다.

• 대한방사선과학회:학술대회논문집
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• 대한방사선과학회 2002년도 학술대회 발표초록
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• pp.19.1-19.1
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• 2002

• Bulletin of the Korean Chemical Society
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• 제33권11호
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• pp.3607-3617
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• 2012

In this paper, the study of various ortho- and meta-substituted Magnolol derivatives is presented. The reaction enthalpies related to three antioxidant action mechanisms HAT, SET-PT and SPLET for substituted Magnolols have been calculated using DFT/B3LYP method in gas-phase and water. Calculated results show that electron-withdrawing substituents increase the bond dissociation enthalpy (BDE), ionization potential (IP) and oxidation/reduction enthalpy (O/RE), while electron-donating ones cause a rise in the proton dissociation enthalpy (PDE) and proton affinity (PA). In ortho- position, substituents show larger effect on reaction enthalpies than in meta-position. In comparison to gas-phase, water attenuates the substituent effect on all reaction enthalpies. In gas-phase, BDEs are lower than PAs and IPs, i.e. HAT represents the thermodynamically preferred pathway. On the other hand, SPLET mechanism represents the thermodynamically favored process in water. Results show that calculated enthalpies can be successfully correlated with Hammett constants (${\sigma}_m$) of the substituted Magnolols. Furthermore, calculated IP and PA values for substituted Magnolols show linear dependence on the energy of the highest occupied molecular orbital ($E_{HOMO}$).

• 한국기계가공학회지
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• 제18권6호
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• pp.55-61
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• 2019

The purpose of this study was to numerically analyze the heat flow characteristics of an automotive radiator. Heat flow analyses were conducted on the cooling water and outdoor air of the radiator, as well as the temperature distribution of the cooling water after heat transfer. The results of the study revealed that neither heat transfer nor radiator volume was affected by the position of the inlet of cooling water. However, temperature distribution was affected by the position of both the inlet and outlet. In case of heat transfer, three models underwent about 158 kW of heat transfer. The difference in cooling water temperature was about $10^{\circ}C$. In case of pressure drop, the core external air side was reduced to about 1,375 Pa, and the internal cooling water side about 14,570 Pa.

• Hip & pelvis
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• 제34권4호
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• pp.203-210
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• 2022

Purpose: Total hip arthroplasty (THA) using the direct anterior approach (DAA) is known to have a learning curve. The purpose of this study was to review cases where surgery was performed by an arthroplasty surgeon transitioning from the posterior approach (PA) to the DAA. We hypothesized similar complication rates and improvements in surgical duration over time. Materials and Methods: A review of 2,452 consecutive primary THAs was conducted. Surgical duration, length of stay (LOS), surgical complications, decrease in postoperative day (POD) 1 hemoglobin, transfusion rates, POD 0 and POD 1 pain scores, incision length, leg length discrepancy (LLD), and radiographic cup position were recorded. Results: No differences in surgical duration were observed after the first 50 DAA cases. A shorter LOS was observed for the DAA, and statistical difference was appreciated after the first 100 DAA cases. There were no differences in periprosthetic fractures. A higher rate of infections and hip dislocations were observed with the PA. The PA showed an association with higher transfusion rates without significant difference in POD 1 decrease in hemoglobin over the first 100 DAA cases. Similar POD 0 and POD 1 pain scores with a smaller incision were observed for the first 100 DAA cases. The DAA cohort showed less variation in cup inclination, version, and LLD. Conclusion: DAA is safe and non-inferior in terms of reduced LOS, smaller incision, and less variation in cup position. Fifty DAA cases was noted to be the learning curve required before no differences in duration between approaches were observed.

• 한국미생물·생명공학회지
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• 제40권4호
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• pp.409-413
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• 2012

인돌리시딘(indolicidin)은 소의 호중구(bovine neutrophils)로 부터 분리된 13개의 아미노산 잔기로 이루어 지고, 트립토판(tryptophan)을 많이 함유한 항균 펩타이드(antimicrobial peptide)이다. 인돌리시딘은 강력한 항균활성과 더불어 mammalian cells에 대해 독성을 나타낸다. 본 연구에서는 인돌리시딘 보다 서열이 짧으며, 보다 증가된 원핵세포 선택성(박테리아세포에 대해 독성을 나타내지만 mammalian cells에 대해서는 독성을 나타내지 않음을 의미함)을 지닌 새로운 짧은 항균 펩타아드를 개발하기 위해, 몇 종의 인돌리시딘 유사체 펩타이드를 설계하고 합성하였다. 결과적으로, 인돌리시딘 보다 서열이 짧으며(10개의 아미노산 잔기로 이루어짐), 증가된 원핵세포선택성을 지닌 4종의 새로운 펩타이드(SI, SI-PA, SI-WF 및 SI-WL)를 개발하였다. 본 연구를 통하여 가장 높은 원핵세포선택성을 나타내는 인돌리시딘 유사체 펩타이드 SI의 항균활성에는 중앙부위에 위치하는 소수성 및 방향족 아미노산이 중요하며, 2군데의 프로린(proline) 잔기는 중요하지 않다는 것을 알았다. 인돌리시딘과 유사체 펩타이드에 대한 원핵세포 선택성은 SI>SI-PA>SI-WF>SI-WL>ID>SI-WA의 순서 이였다. 따라서, 본 연구에서 설계되고 합성한 4종의 인돌리시딘 유사체 펩타이드(SI, SI-PA, SI-WF 및 SI-WL)는 박테리아 감염의 치료제로서 개발될 수 있을 것이다.

• Animal Bioscience
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• 제35권1호
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• pp.105-114
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• 2022

Objective: This work was carried out to evaluate the effect of pasture (PA) feeding on buffalo meat quality compared with buffaloes reared intensively with the use of corn silage as a forage base or alternatively with polyphite meadow hay (PH). Methods: Thirty Mediterranean bull buffaloes were distributed into three experimental diet groups: maize silage (MS), PH, and PA. The animals were slaughtered at a live weight of 250 kg, and carcass and meat quality were evaluated. After 7 days of ageing, physical and chemical parameters of longissimus thoracis muscle were determined. To evaluate lipid oxidation the thiobarbituric acid reactive substances was tested at 7 and 14 days, and also the fatty acid profile was recorded by gas chromatography. Results: The PA group, even if it showed carcass parameters lower than those of the silage maize group, reported a good meat percentage (60.59% vs 58.46%, respectively) and lower fat percentage (p<0.001). PA-fed animals showed meat redness, and even if only on raw meat, shear force was higher than the others. Low values of conjugate linoleic acid, polyunsaturated fatty acids, and n-3 were reported in the silage maize group. Principal component analysis (PCA) clearly showed the influence of different diets on meat quality, and PCA1 and PCA2 explained 82% of the variability. Conclusion: Buffaloes reared on PA had meat with high nutritional value even if they showed poor carcass performance compared to the animals fed on MS. Buffaloes fed on polyphite hay were in an intermediate position, similar to grazing animals, according to the same nutritional determinations.

• Bulletin of the Korean Chemical Society
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• 제19권5호
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• pp.527-530
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• 1998

This paper presents the electrochemistry and molecular orbital (MO) picture of a series of conformationally-restricted thioxantone derivatives. A series of $C_2-substituted$ thioxanthones were examined to probe the electronic influence of the substituent on the electrooxidation and electroreduction sites (i.e., on the electron densities at the 10-and 9-positions), respectively. In the presence of "electrophoric" groups such as C=O and S, characteristic electrochemical reduction and oxidation responses are observed. The electrochemical reaction was diffusion-controlled, because the $I_p/{\upsilon}^{1/2}$ ratio was constant for the anodic and cathodic wave of thioxantone derivatives. These substituent effects are presented in terms of correlations of oxidation (or reduction) potentials with the highest occupied molecular orbital (HOMO), or lowest unoccupied molecular orbital (LUMO) energies, respectively. There is good correlation between energies of the HOMO vs. $E_{pa}^{(+)}$ and energies of the LUMO vs. $E_{pc}^{(-)}$. Frontier Molecular Orbital (FMO) is changed by the functional group of thioxanthones. FMO energy level was offered us the information about the electron transfer direction, and the coefficient of FMO was offered the information about the electron transfer position. Sulfur atom has an important effect on oxidation potential, $E_{pa}^{(+)}$ and the carbonyl carbon has an important effect on reduction potential, $E_{pc}^{(-)}$. Therefore we were appreciated that the contribution of sulfur atom for the $E_{pa}^{(+)}$ and HOMO energies is larger than the contribution of carbonyl group for the $E_{pc}^{(-)}$ and LUMO energies.