• Title/Summary/Keyword: P91

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The Effect of WY-91 Preparation on Experimental Liver Injury in Mice (실험적 간장해에 대한 WY-91제제의 영향)

  • Han, Sang Soo;Sohn, Dong Hwan;Kim, Jae Baek
    • Korean Journal of Clinical Pharmacy
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    • v.3 no.2
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    • pp.157-162
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    • 1993
  • The present study was designed to examine the effect of tested preparation, WY-91 (consisting of ginseng extract, ganoderma extract and Royal jelly) on alcohol-induced unusual metabolism(such as blood glucose(BG), triBlyceride(TG), and blood urea nitrogen(BUN) level in blood) and nrperinlental liver injury($CCl_4$ and high fat diet) in mice. WY-91 lowered the level of blood glucose (BG),triglyceride(TG) and blood urea nitrogen(BUN) induced by alcohol in a dose-dependent manner. This preparation could protect hepatic function from a damages caused by high fat diet and $CCl_4$ administration(p.o.).

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Effects of hardness values on the creep rupture strength in a Mod. 9Cr1Mo Steel (Mod. 9Cr1Mo 강의 크리프 강도에 미치는 경도의 영향)

  • Lee, Yeon-Su;Yu, Seok-Hyeon;Gong, Byeong-Uk;Kim, Jeong-Tae
    • Proceedings of the KSME Conference
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    • 2003.04a
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    • pp.637-642
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    • 2003
  • The Modified 9Cr-1Mo steel identified as T91, P91 and F91 in the ASME specification has been widely used for the construction of modern power plants. The available data on the influence of process parameters during manufacturing and fabrication on its properties are not sufficient. In this study, the influence of various thermal cycles on the hardness and the creep rupture strength was analyzed in the base metal and the weldments made in tube and pipe of a Mod.9Cr-1Mo steel. The low hardness, 155Hv, showed low creep rupture strength below the allowable stresses of T91 base metal in the ASME specification. This low value was attributed to the fully recovered dislocation structure and the weakening of precipitation hardening associated with the abnormal thermal cycles.

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Nurses' Monitoring Practice for Adverse Drug Reactions (약물 유해 반응에 대한 간호사의 모니터링 실천에 관한 연구)

  • Kim, Hyun-Jin;Lee, Seon-Hye
    • Journal of Korean Academy of Nursing Administration
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    • v.22 no.1
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    • pp.91-98
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    • 2016
  • Purpose: The aim of this study was to identify the relationship between nurses' knowledge of adverse drug reactions (ADR), attitudes, and monitoring practices and to establish an effective ADR reporting system and provide baseline data for its activation. Methods: The participants in this study were chosen by convenience sampling and included 182 nurses working at major general hospitals that operate a Regional Drug Safety Center. Data were collected from June 1 to 12, 2015 and analyzed using Cronbach's ${\alpha}$, descriptive statistics, independent t-test, one way ANOVA, Pearson correlation coefficient and stepwise regression with the SPSS program. Results: The nurses' average score for knowledge was 7.62 points, for attitude, 41.04 points and for monitoring practices, 34.22 points. ADR monitoring practices positively correlated with knowledge (r=.19, p=.011), attitude (r=.41, p<.001), drug performance competency (r=.54, p<.001), and drug education satisfaction (r=.54, p<.001). Drug performance competency, drug education satisfaction, and attitudes explained 42.0% of the ADR monitoring practices (Adj $R^2=.42$, F=43.95, p<.001). Conclusion: In order to facilitate and encourage nurses' voluntary monitoring practice of ADR, efforts must be made to create positive attitudes toward ADR, and to increase drug performance competency and drug education satisfaction.

Effect of Starch Noodle (Dangmyeon) and Pork Intestines on the Rehydration Stability of Korean Blood Sausage (Sundae)

  • Kim, Youngmin;Jang, Hyejin;Lim, Sangdong;Hong, Sangpil
    • Food Science of Animal Resources
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    • v.41 no.1
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    • pp.153-163
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    • 2021
  • This study was conducted to examine the effects of starch noodles (dangmyeon; SNs) with different starch sources and porcine intestines (PIs) with different pH on the rehydration stability of Korean blood sausage (sundae). Mungbean SN3 and PI3 (pH 9.18) showed significantly higher values of 80.69%-91.67% and 79.66%-80.98%, respectively, regardless of the drying methods (hot air, vacuum and freeze drying) (p<0.05). A number of larger pores were observed only in the cross-section of the freeze dried SN and PI through SEM. SN2 (potato starch) and PI3 (pH 9.18) showed lower expansion (⁎ΔL 6.90 mm) and higher expansion ratio (⁎ΔL 26.29 mm), respectively, after rehydration of freeze dried sample (p<0.05). From the application of SN2 (potato starch) and PI (0.5%-2.0% Na-pyrophosphate) to freeze dried sundae manufacturing, higher rehydration stability of more than 91.5% was obtained. These results suggested that potato SN and treatment of PI with Na-pyrophosphate is useful for desirable rehydration stability of freeze dried sundae.

Characteristics of Quantiy and Quality for Bulk Precipitation and Stemflow of 5 Tree Species in Mt. Joongwang, Gangwon-do - A Centering Around the pH Value - (강원도 중왕산 지역에서 5개 수종의 임외강우와 수간류의 수량 및 수질특성(I) - pH값을 중심으로 -)

  • Jung, Mun Ho;Lee, Kwang Su
    • Journal of Korean Society of Forest Science
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    • v.97 no.3
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    • pp.229-236
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    • 2008
  • The objectives of this study were to investigate inputs and pH values of stemflow of bulk precipitation and 5 tree species (Deciduous species : Quercus mongolica, Betula costata, Kalopanax septemlobus, Fraxinus rhynchophylla, Plantation species : Larix kaempferi), in Mt. Joongwang, Pyongchang-gun, Gangwondo, from June to October in 2004 and 2005. The amount of stemflow during study period was the greatest in Q. mongolica (9.9 mm), and B. costata (7.5 mm), K. setemlobus (5.9 mm), L. kaempferi (3.8 mm), F. rhynchophylla (3.2 mm), respectively. Stemflow of each species increased with bulk precipitation. Increment with bulk precipitation was smaller in 2004 when the intense bulk precipitation occurred more. pH values of stemflow was the highest in F. rhynchophylla (5.91), and K. setemlobus (5.64), B. costata (5.80), Q. mongolica (5.56), L. kaempferi (5.25), respectively. Generally, pH values of stemflow of all species increased with bulk precipitation pH value, and lower than that (6.39).

Synthesis of Resin Derivatives and Purification of Protein - Synthesis of p-Aminoanilinylsuccinyl-AH-Sepharose 4B and Purification of Protein in Pleurotus cornucopiae - (친화성 고분자 유도체의 합성 및 단백질의 분리정제에 관한 연구 - p-Aminoanilinylsuccinyl-AH-Sepharose 4B의 합성 및 흰느타리버섯 중 단백질의 정제 -)

  • Min, Tae-Jin;Kim, Yong-Rip;Park, Sang-Shin;Lee, Soo-Yong
    • The Korean Journal of Mycology
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    • v.17 no.3
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    • pp.105-113
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    • 1989
  • For selective purification of proteins in Pleurotus cornucopiae, affinity chromatography was performed by p-aminoanilinylsuccinyl-AH-Sepharose 4B gel synthesized by treating p-phenylene diamine with succinyl-AH-Sepharose 4B, which was prepared by treating AH-Sepharose 4B with succinic anhydride. The capacity of p-aminoanilinyl ligand group was 6.1 micromole per milliliter of gel. Total apparent molecular weight of the affinity proteins eluted from the synthesized gel was 167 KD, which were a protein complex of 130 KD and 37 KD. The contents of the nonpolar, polar, positively and/or negatively charged amino acids in the affinity protein were 44.57%, 24.75%, 21.25%, and 9.43%, respectively. Total apparent molecular weight of the affinity proteins eluted from the AH-Sepharose 4B gel was 95.2 KD, which were a protein complex of 61 KD, 31 KD and 3.2 KD. The contents of the nonpolar, positively and/or negatively charged amino acids in the affinity protein by AH-Sepharose 4B gel were 44.05%, 29.13%, and 12.91% respectively.

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A Study on the Reduction of Cross-talk Artifact in Lumbar Magnetic Resonance Imaging : Focused on Concatenation Time Repetition (요추 자기공명영상에서 발생하는 Cross-talk Artifact 저감화 연구: 분할 TR 중심으로)

  • Lee, Jae-Heun;Lee, Hyo-Yeong
    • Journal of the Korean Society of Radiology
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    • v.14 no.5
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    • pp.715-723
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    • 2020
  • Cross-talk artifacts occur in two adjacent groups of axial imaging of lesions lumbar 4-5 and sacrum 1 in lumbar spine MRI. This causes problems in reading lesions in areas corresponding to the posterior vertebra. In this study, we are going to completely remove the cross-talk artifacts through optimal concatenation TR. The region of interested were measured by averaging them into fat (ROI1), erector spinal muscle(lateral tract: iliocostalis lumborum muscle) (ROI2), erector spinal muscle(lateral tract: longissimus muscle) (ROI3), and spinous process (ROI4). The mean signal intensity (SI) was 163.43 ± 25.08 at C4 for ROI1, ROI 2 and ROI 3 at C6, 67.89 ± 11.75 and 69.99 ± 10.91 and ROI4 at C5, respectively (p<0.000). The mean signal to noise ratio (SNR) was 135.45 ± 35.90, 56.92 ± 15.90, 58.77 ± 15.59, and 54.91 ± 118.95 for SNR 1, 2, 3 and 4 (p<0.000). The contrast-to-noise ratio (CNR) was CNR1 78.52 ± 24.11, CNR2 was 76.67 ± 24.38 and CNR3 was 80.54 ± 26.33 in concatenation 6, respectively (p<0.000). The SNR, CNR, and the most efficient concatenation TR value over time are 6, and it is considered to help reduce cross-talk artifact if this is applied to T1 axial images.

Antioxidant and Anti-inflammatory Effects of Plantago asiatica L. Extract (질경이 추출물의 항산화 및 항염증 활성)

  • Choi, Yukyung;Choo, Byung-Kil
    • Korean Journal of Organic Agriculture
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    • v.32 no.1
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    • pp.91-105
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    • 2024
  • Plantago asiatica L. (P. asiatica) is a perennial plant belonging to the plantaginaceae and is useful in treating a various diseases such as wounds, bronchitis, and chronic constipation. The bioactive effects of P. asiatica extract was evaluated to determine its potential for use as a variety materials in the food, pharmaceutical, and agricultural industries. Polyphenol and flavonoid contents, free radical scavenging, reducing power activity, and reactive oxygen species (ROS) expression were measured to identify the antioxidative activity. Anti-inflammatory effects were evaluated via analysis of nitric oxide (NO) and pro-inflammatory protein expression in LPS-induced RAW 264.7 cell. As a result of measuring the antioxidant activities of the P. asiatica extract, the total polyphenol content was 50.91±0.78 mg gallic acid equivalents/g and the flavonoid content was 100.99±0.44 mg rutin equivalents/g, and both DPPH and ABTS radical scavenging activities and reducing power increased depending on the concentration. Also, intracellular ROS production was inhibited by the P. asiatica extract. No cytotoxicity was observed when P. asiatica extract was treated, and NO and inflammatory protein expression were inhibited, and nuclear factor kappa B (NF-κB) phosphorylation was also inhibited in a concentration-dependent manner. In conclusion, P. asiatica is a functional natural resources of antioxidant and anti-inflammatory agents that can be used in various industries, including food and agriculture.

Feasibility of Cheonghju Brewing with Wild Type Yeast Strains from Nuruks (누룩으로부터 분리한 Wild Type 효모의 청주(淸酒)제조 가능성에 관한 연구)

  • Kim Hye-Ryun;Baek Seung-Hee;Seo Min-Jae;Ahn Byung-Hak
    • Microbiology and Biotechnology Letters
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    • v.34 no.3
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    • pp.244-249
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    • 2006
  • In order to select the best strains to have the feasibility of Cheonghju brewing, 10 wild type yeast strains from 300 different types of Nuruk were investigated on their ethanol resistance, resistance to glucose and flocculation. The amounts of alcohol, organic acids, and volatile compounds, Brix, pH were also examined for the alcoholic beverages made with the 10 selected strains. Almost all strains showed alcohol production activities in the medium containing 18%(v/v) ethanol and 29%(w/v) glucose. The strains 90-2 showed a higher flocculation activity than other strains. Strains 54-3, 90-2 and 91-5 produced more alcohol than control strain (7.42%(w/w)) when fermented with wild type yeast strains. In addition, alcoholic beverages containing low acetic acid also showed low levels of total acidity. GC/MS analysis of the product showed 4 alcohols, 11 esters and 1 acid as volatile compounds. Selected strains were tentatively identified as Phichia sydowiorum (91-5), Zygosaccharomyces cidri (192-2 and 271-4), and as Saccharomyces cerevisiae (18-2, 54-3, 90-2, 91-2, 98-2, 99-5 and 272-7) by BIIOLOG method.

Effect of Soil pH on Growth and Flower Color in Hibiscus siriacus L. (토양산도가 무궁화의 생장 및 화색에 미치는 영향)

  • Park Hyung-Soon;Chung Hun-Gwan;Kim Sea-Hyun;Chung Dong-Jun;Han Jin-Gyu;Cho Yoon-Jin
    • Korean Journal of Plant Resources
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    • v.19 no.1
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    • pp.144-149
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    • 2006
  • This is a study on relationship between soil pH and flower color and growth of Hibiscus siriacus L, looking for the pH range to result the most ideal flower color. I anticipate this study result will lay a foundation of improved breeding plan of Hibiscus siriacus L. According to the result of investigation and analysis on bleeding peculiarities by each soil pH, the numbers of leaves in Honghwarang and Younggwang reached the highest at pH 7: 188.73 and 135.87 respectively. Increased pH resulted the increased number of leaves. According to the result of investigation and analysis on color changes of four kinds of Hibiscus siriacus L. at various pH level, Honghwarang's L value gradually decreased from 17.05 to 12.26 at pH increase while a value increased from 16.37 to 20.91.