• Analytical Science and Technology
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• v.33 no.5
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• pp.215-223
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• 2020

The objectives of the present study were to assess the oxidative stability of South Korean n-3 (omega-3 fatty acid) supplements carried out from 2018 to 2019 and evaluate the influence of product characteristics on oxidative safety. A total of 76 n-3 supplements were analysed for oxidation safety by four markers, including acid value (AV), primary oxidation (peroxide value, PV), secondary oxidation (p-anisidine value, pAV) and total oxidation value (TOTOX). Among the supplements tested, 5.3 %, 55.3 %, 28.9 % and 46.1 % exceeded the international voluntary recommended levels for AV, PV, pAV and TOTOX, respectively. Purity (%) of products, remainder of expiration date (suggested shelf life), package in press through package (PTP) and products with additives had statistically significant differences oxidation assessment levels (p < 0.05). In addition, n-3 group found in Algae oil had significantly lower AV levels than the group that did not, and product with Alaska pollack oil, had significantly higher pAV levels than without group (p < 0.05). The high oxidation status of South Korean n-3 products in the present study could not be considered a public health problem right now. However, the levels of oxidation may affect a lot the efficacy and safety of using n-3 supplements. Thus, current oxidation safety limits should be reestablished by regulatory bodies to ensure the safety and efficacy of n-3 supplements, so that the standards could be applied to the products available to consumers.

• Genomics & Informatics
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• v.20 no.2
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• pp.20.1-20.13
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• 2022

Recent studies have focused on the early detection of ovarian cancer (OC) using tumor materials by liquid biopsy. The mechanisms of microRNAs (miRNAs) to impact OC and signaling pathways are still unknown. This study aims to reliably perform functional analysis of previously validated circulating miRNAs' target genes by using pathfindR. Also, overall survival and pathological stage analyses were evaluated with miRNAs' target genes which are common in the The Cancer Genome Atlas and GTEx datasets. Our previous studies have validated three downregulated miRNAs (hsa-miR-885-5p, hsa-miR-1909-5p, and hsa-let7d-3p) having a diagnostic value in OC patients' sera, with high-throughput techniques. The predicted target genes of these miRNAs were retrieved from the miRDB database (v6.0). Active-subnetwork-oriented Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis was conducted by pathfindR using the target genes. Enrichment of KEGG pathways assessed by the analysis of pathfindR indicated that 24 pathways were related to the target genes. Ubiquitin-mediated proteolysis, spliceosome and Notch signaling pathway were the top three pathways with the lowest p-values (p < 0.001). Ninety-three common genes were found to be differentially expressed (p < 0.05) in the datasets. No significant genes were found to be significant in the analysis of overall survival analyses, but 24 genes were found to be significant with pathological stages analysis (p < 0.05). The findings of our study provide in-silico evidence that validated circulating miRNAs' target genes and enriched pathways are related to OC and have potential roles in theranostics applications. Further experimental investigations are required to validate our results which will ultimately provide a new perspective for translational applications in OC management.

• The Korean Journal of Mycology
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• v.30 no.1
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• pp.66-72
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• 2002

To develop DNA markers for analysis of genetic characteristics of Phytophthora capsici population, randomly selected clones from HindIII-digested genomic DNA library of P. capsici 95CY3119 were surveyed by hybridizing to Southern blots of HindIII-digested total genomic DNA of P. capsici. Probe DNAs inserted into selected individual clones strongly hybridized with HindIII digests of P. capsici. Among probes examined, PC9 revealed the repetitive and highly polymorphic bands to HindIII digests of inter-and intra-field P. capsici isolates. Genetic diversity of individual isolates was also clearly revealed in cluster analysis based on its band patterns. The other probe, PC22, was hybridized only to DNA from P. capsici and this was highly repetitive. However, there was no response to other Phytophthora species and Pythium sp. These DNA probes could be used as very useful markers in analysing genetic diversity and identification for P. capsici population throughout the world.

• Journal of KIISE:Software and Applications
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• v.27 no.3
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• pp.210-216
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• 2000

Place/Transition(P/T) nets has been used in protocol verification and concurrent system verification since it is suitable for describing concurrency and provides several well-established verification techniques. And it has been used as a base formalism for such high-level Petri nets as colored Petri nets, object-oriented Petri nets and etc. However, when analyzing complex models using P/T nets and P/T nets-based high-level Petri nets, there may be state explosion in reachability analysis due to improper handling of concurrency. In this paper, we define a structural concurrency in P/T nets, propose a partitioning algorithm based on the detected structural concurrency, and provide analysis techniques for such properties as boundedness of places and liveness of transitions, which are performed on compositional reachability graphs. The analysis techniques based on Petri net slices can be used in efficiently analyzing P/T nets-based high-level Petri net models as well as P/T net models.

• The Journal of the Korea Contents Association
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• v.5 no.5
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• pp.172-181
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• 2005

The latest attack type against network traffic appeared by worm and bot that are advanced in DDoS. It is difficult to detect them because they are diversified, intelligent, concealed and automated. The exisiting traffic analysis method using SNMP has a vulnerable problem; it considers normal P2P and other application program to be harmful traffic. It also has limitation that does not analyze advanced programs such as worm and bot to harmful traffic. Therefore, we analyzed harmful traffic out Protocol and Port analysis. We also classified traffic by protocol, well-known port, P2P port, existing attack port, and specification port, apply singularity weight to detect, and analyze attack availability. As a result of simulation, it is proved that it can effectively detect P2P application, worm, bot, and DDoS attack.

• Journal of the Korea Convergence Society
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• v.12 no.9
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• pp.65-71
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• 2021

The purpose of this study is to investigate the factors that affect stress, emotional regulation, and adjustment to college life of health college students. The survey was conducted from June 21 to 30, 2021 for 190 health students in G and J area. The data were analyzed by frequency analysis, reliability analysis, simple correlation analysis, and multiple regression analysis. The results showed that positive perception had positive correlation with negative perception(r=-.286,p<.01), emotional regulation (r=.296,p<.01), and university life adjustment(r=.520,p<.01). Negative perception was correlated with emotional regulation(r=-.619,p<.01), university life adjustment (r=-.428,p<.01) and negative(-). Emotional regulation had a positive correlation with university life adjustment(r=.341,p<.01). Positive perception, negative perception, and emotional regulation, which are sub-factors of perceived stress, were the factors affecting the adjustment to university life, and the explanatory power was 84%. Therefore, it is necessary to develop a program that can improve the adjustment of college students in health.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• v.60 no.9
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• pp.454-462
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• 2017

Background and Objectives The present study aimed to investigate the effects of penetration/aspiration (P/A) on voice acoustic parameters. Subjects and Method Twenty-seven patients were analyzed with the videofluoroscopic swallowing study (VFSS) and then divided into two groups based on the modified Penetration and Aspiration Scale results. Ten patients (5 males and 5 females) were included in the Non-P/A group, and 17 patients (12 males and 5 females) in the P/A group. Stroke was the major cause of swallowing disorders. Three sustained /a/ vowels recorded in pre- and post-VFSS were analyzed. Mann-Whitney U-test was used to compare acoustic values before and after VFSS, and the receiver operating characteristics (ROC) curve with combination of significant parameters was also conducted. Results Among acoustic parameters, the length of analyzed sample (p=0.010), number of segments computed (p=0.018), total number detected pitch periods (p=0.017), and second formant (p=0.013) in pre- and post-VFSS were significantly different between Non-P/A and P/A groups. In the P/A group after VFSS, the means of these significant parameters decreased. According to ROC combined with four significant parameters, the probability of predicting P/A condition was 84% (p=0.005), the sensitivity was 80%, and the specificity was 80%. Conclusion Voice acoustic analysis can reflect voice changes by penetration/aspiration and the combination of significant parameters can also detect swallowing disorders. Therefore, voice analysis can be a reliable screening tool for patients with swallowing disorders.

• Journal of Agricultural Extension & Community Development
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• v.22 no.3
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• pp.321-332
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• 2015

For the purpose of enhancing the use of social service in classrooms, this research focuses on the relationships between presence and learning flow, key words in the analysis of college classes using Facebook. The results of this study are as follow. First, social presence(${\ss}=.33$, p=.000), emotional presence(${\ss}=.29$, p= .000), cognitive presence(${\ss}=.20$, p= .010) were found to be significant according to cognitive flow experience the result of analysis of multiple regression. all regression coefficients were positive. Second, emotional presence(${\ss}=.42$, p=.000) and social presence(${\ss}=.27$, p=.000), cognitive, presence(${\ss}=.17$, p=.015) were found to be significant according to emotional flow experience the result of analysis of multiple regression. all regression coefficients were positive. Third, social presence(${\ss}=.37$, p=.000) of the three variables were found to be significant according to behavioral flow experience the result of analysis of multiple regression.

• The korean journal of orthodontics
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• v.21 no.3
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• pp.501-511
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• 1991

This study was performed to verify the craniofacial skeletal characteristics in anterior openbite group, in contrast to normal occlusion group, and also to find out, vertical factors which shows, correlate to the amount of anterior openbite. 21 individuals, including 10 males and 11 females, without orthodontic treatment history and anterior - posterior skeletal malrelationships, were selected and analyzed basic morphology and vertical factors, using standard lateral cephalogram. The obtained results as follows: 1. Comparison of anterior open-bite group with normal occlusion group using Moyers analysis. a) In basis morphologic analysis, Ba-SE-Me was lesser and Ba-SE-Mn. P. and Mn.P/A-B were greater in both sexes of anterior openbite group than in normal occlusion group. b) In angle measurements of vertical analysis, PMV/Pal. P. was lesser in male anterior openbite group and PMV/Occ. P. and PMV/Mn. P. were greater in both sexes of anterior openbite group than in normal occlusion group. c) In height ratio of vertical analysis, ATFH/PTFH and ALFH/ATFH were greater in both sexes of anterior openbite group than in normal occlusion group. 2. The amount of anterior openbite was correlated with PMV/Occ. P. and PMV/Mn. P.

• International Journal of Advanced Culture Technology
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• v.8 no.2
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• pp.18-27
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• 2020

This study was cross sectional descriptive survey study to analysis effect of health perception and mental health status on the quality of life in the late middle aged people (45-65 years old). The data for the study were collected online from November 20 to December 10, 2019, from those who agreed to participate in the study voluntarily. A total of 192 data were used for the study. This study analyzed the Pearson correlation analysis, Descriptive analysis and Regression analysis using SPSS 18.0. As a result, the participants were 41.7% male and 58.3% female. The age group was 45-50 years old 4.2%, 51-55 years old 20.8%, 56-60 years old 54.1% and 61-65% 20.8%. Mental health status was associated with physical QOL(r=-347, p<0.01), Psychological QOL(r=-.439, p<0.01), and Social QOL(r=.280, p<0.01). Subjective health perception was associated with physical QOL(r=-589, p<0.01), Psychological QOL(r=.222, p<0.01), and Social QOL(r=.286, p<0.01). subjective health perception was found to affect all sub-factors except environmental quality of life under the statistical significance (p<0.01).