• Journal of Technologic Dentistry
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• v.41 no.4
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• pp.287-293
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• 2019

Purpose: To evaluate the accuracy of the 3D printed die models and to investigate its clinical applicability. Methods: Stone die models were fabricated from conventional impressions(stone die model; SDM, n=7). 3D virtual models obtained from the digital impressions were manufactured as a 3D printed die models using a 3D printer(3D printed die models;3DM, n=7). Reference model, stone die models and 3D printed die models were scanned with a reference scanner. All dies model dataset were superimposed with the reference model file by the "Best fit alignment" method using 3D analysis software. Statistical analysis was performed using the independent t-test and 2-way ANOVA (α=.05). Results: The RMS value of the 3D printed die model was significantly larger than the RMS value of the stone die model (P<.001). As a result of 2-way ANOVA, significant differences were found between the model group (P<.001) and the part (P<.001), and their interaction effects (P<.001). Conclusion: The 3D printed die model showed lower accuracy than the stone die model. Therefore, it is necessary to further improve the performance of 3D printer in order to apply the 3D printed model in prosthodontics.

• Food Science and Biotechnology
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• v.17 no.6
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• pp.1349-1351
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• 2008

This study examined the effects of temperature, D-psicose concentration, pH, and various amino acids on the Maillard browning reaction of D-psicose and glycine mixture and compared browning color intensity with those of other sugars, such as sucrose, D-glucose, D-fructose, and D-tagatose. When D-psicose (0.1 M) and glycine (0.1 M) mixture was heated at $70-100^{\circ}C$ for 5 hr, the absorbance at 420 nm increased with increasing reaction temperature and time. The Hunter a, b values, and color difference (${\Delta}E$) increased with increasing D-psicose concentration and pH within the range of pH 3-7 except at pH 6, while the L value decreased. The rate of Maillard browning reaction was in order of D-tagatose>D-psicose $\fallingdotseq$ D-fructose>D-glucose>sucrose. The browning color intensity of the D-psicose-basic and non-polar amino acids mixtures was higher than that of the D-psicose-acidic amino acids.

• Toxicological Research
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• v.34 no.4
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• pp.325-332
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• 2018

The mechanism of the previously reported antidiabetic effect of Basella alba is unknown. This study investigated the role of B. alba aqueous leaf extract in the modulation of inflammatory cytokines and islet morphology in streptozotocin-induced diabetic rats. Forty male Wistar rats, between 8 and 10 weeks old, were randomly divided into four groups (n = 10) and administered the following treatments: Healthy control (H-c) and Diabetic control (D-c) animals received normal saline 0.5 mL/100 g body weight daily, while Healthy Treatment (H-Ba) and Diabetic Treatment (D-Ba) rats received the plant extract 200 mg/kg body weight daily. All treatments were administered by oral gavage. Diabetes was induced in D-c and D-Ba rats by a single intraperitoneal injection of streptozotocin (55 mg/kg body). The body weight and fasting blood sugar (FBS) levels were recorded every week for 4 weeks, after which the rats were euthanized and samples collected for further analysis. After the experiment, FBS level was significantly reduced (p < 0.0001) in rats in the D-Ba group, but increased (p < 0.001) in rats in the D-c group. The absolute (H-c and H-Ba vs D-c, p < 0.05) and relative (D-Ba vs H-c, p < 0.05; D-Ba vs H-Ba, p < 0.005) weights of the pancreases were significantly higher after the experiment. The rats in the D-c group had significantly higher levels of serum interleukin-$1{\beta}$ (p < 0.001 vs H-c; p < 0.05 vs H-Ba and D-Ba) and monocyte chemotactic protein-1 (p < 0.0001), but lower levels of interleukin-10 (p < 0.05) in comparison with the other groups. Histopathological examination revealed severe interstitial congestion, reduced islet area (p < 0.0001), and increased islet cell density in the D-c group compared with those in the D-Ba group. From these findings, it was concluded that the aqueous extract of B. alba stimulates the recovery of beta-islet morphology in streptozotocininduced diabetic rats by modulating the peripheral production of inflammatory cytokines.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3741-3745
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• 2014

Background: Emerging evidence implicates the platelet-derived growth factor-D (PDGF-D) in many types of human solid tumors. We investigated whether PDGF-D plays an important role in endometrial cancer (EC) in relation to clinicopathologic phenotype, angiogenesis, and patient prognosis. Materials and Methods: We analyzed PDGF-D protein expression by Western blotting in twenty-seven human endometrial cancer tissues, and matched normal endometrial controls collected at the third Affiliated hospital of Sun Yat-sen University during 2012-2013 (n=27). Immunohistochemical staining was performed using a human PDGF-D antibody on the endometrial cancer patients collected in the same facility during January 2001 and October 2013 (n=152). Patients were followed from the time of primary surgery in 2001-2013 until death or last follow-up. We correlated the PDGF-D expression levels with clinicopathologic parameters and prognosis in human endometrial cancer patients. Results: Compared with matched normal endometrial cases, PDGF-D was up-regulated in endometrial cancer. Expression of PDGF-D protein, found in 78% of the cases, was associated with nonendometrioid histologic type (p=0.028), FIGO stage III/IV (p=0.039), >50% solid tumor growth (p=0.048), pelvic LN metastasis (p=0.035) and ER and PR negativity (p=0.04 and 0.002). PDGF-D expression was also significantly associated with expression of VEGF-A (p=0.021). In multivariate analysis, PDGF-D expression proved to be an independent prognostic factor in addition to histologic grade and FIGO stage. Patients with high expression levels of PDGF-D had a significantly poorer overall survival rate compared with patients with no expression. Conclusions: PDGF-D expression is frequently up-regulated in endometrial cancer, and is associated with aggressive features and poor prognosis.

• Proceedings of the Korea Society of Poultry Science Conference
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• 2001.11a
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• pp.99-101
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• 2001

Three experiments were conducted with broilers to study the effects of early feed restriction. In all studies, treatments were represented by three replicated floor pens, each containing 20 birds. In Experiment 1, broilers were fed at 0.75 kcal ME/g BW/sup0.67 for 3 d, 1.5kcal m/E BW/sup0.67 for 5 d or 2.25 kcal ME/g BW/sup0.67 for 7 d, all imposed beginning at 7 d of age. Birds were smaller following feed restriction(P<0.05), although growth compensation occurred, and at 49 d all restricted birds were same(P>0.05) to full-fed control buds in body weight. Growth compensation was associated with improved feed conversion(P<0.05), although carcass composition was unchanged. In a second study, all birds were fed at 0.75 kcal ME/g BW/sup0.67 for 3 or 5 d, starting at either 4, 7, or 10 d of age. When feed restriction was applied for shorter periods of time, growth compensation occurred(P>0.05). With more severe feed restriction, birds were smaller(P<0.05) at 49 d compared to control. Feed conversion was improved following prior feed restriction(P<0.05, 4 to 49). In a third trial, broilers were fed a starter diet diluted with 50% rice hulls. Birds failed to consume enough of this diluted feed, and so were initially smaller, However 49 d weight was not affected (P>0.05). When periods of 24 h feed withdrawal were imposed in conjunction with the diluted diets, birds were under weight at 49 d. It is concluded that physical feed restriction at 0.75 to 1.5 kcal ME/g BW$\^$0.67 imposed for 3 to 5 d in the early life currently presents the best option as a means of controlling broiler growth so as to improve feed efficiency.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.10
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• pp.1484-1489
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• 2013

The study was conducted to determine the effects of chitosan on the concentrations of GH and IGF-I in serum and small intestinal morphological structure of piglets, in order to evaluate the regulating action of chitosan on weaned pig growth through endocrine and intestinal morphological approaches. A total of 180 weaned pigs (35 d of age; $11.56{\pm}1.61kg$ of body weight) were selected and assigned randomly to 5 dietary treatments, including 1 basal diet (control) and 4 diets with chitosan supplementation (100, 500, 1,000 and 2,000 mg/kg, respectively). Each treatment contained six replicate pens with six pigs per pen. The experiment lasted for 28 d. The results showed that the average body weight gain (BWG) of pigs was improved quadratically by dietary chitosan during the former 14 d and the later 14 d after weaned (p<0.05). Furthermore, dietary supplementation of chitosan tended to quadratically increase the concentration of serum GH on d 14 (p = 0.082) and 28 (p = 0.087). Diets supplemented with increasing levels of chitosan increased quadratically the villus height of jejunum and ileum on d 14 (p = 0.089, p<0.01) and 28 (p = 0.074, p<0.01), meanwhile, chitosan increased quadratically the ratio of villus height to crypt depth in duodenum, jejunum and ileum on d 14 (p<0.05, p = 0.055, p<0.01) and 28 (p<0.01, p<0.01, p<0.01), however, it decreased quadratically crypt depth in ileum on d 14 (p<0.05) and that in duodenum, jejunum and ileum on d 28 (p<0.01, p<0.05, p<0.05). In conclusion, these results indicated that chitosan could quadratically improve growth in weaned pigs, and the underlying mechanism may due to the increase of the serum GH concentration and improvement of the small intestines morphological structure.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.9
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• pp.57-67
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• 2016

This study is designed to investigate the differences of ferritin and hemoglobin levels according to the vitamin D state in 23577 Korean adult subjects by using data from the Korea National Health and Nutrition Examination Survey IV, V. Ferritin and hemoglobin levels are analyzed based on the quintile of vitamin D levels by a generalized linear model. The results of analysis showed that there was a relationship between vitamin D state and hemoglobin levels in females in the reproductive status group (p<0.001). In case of ferritin, there was a relationship with vitamin D state in females in reproductive status group (p<0.001) and males under 65 years old group (p<0.05). Within the male group, high ferritin correlated with low vitamin D state; but in the female group, high ferritin correlated with high vitamin D state. Therefore, it is possible for the ferritin level to be affected by vitamin D state in females in reproductive status group and males under 65 years old group.

• The Journal of Korean Academy of Prosthodontics
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• v.57 no.3
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• pp.225-231
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• 2019

Purpose: This study was undertaken to compare fracture and flexural strength of provisional restorative resins fabricated by additive manufacturing, subtractive manufacturing, and conventional direct technique. Materials and methods: Five types of provisional restorative resin made with different methods were investigated: Stereolithography apparatus (SLA) 3D printer (S3Z), two digital light processing (DLP) 3D printer (D3Z, D3P), milling method (MIL), conventional method (CON). For fracture strength test, premolar shaped specimens were prepared by each method and stored in distilled water at $37^{\circ}C$ for 24 hours. Compressive load was measured using a universal testing machine (UTM). For flexural strength test, rectangular bar specimens ($25{\times}2{\times}2mm$) were prepared by each method according to ISO 10477 and flexural strength was measured by UTM. Results: Fracture strengths of the S3Z, D3Z, and D3P groups fabricated by additive manufacturing were not significantly different from those of MIL and CON groups (P>.05/10=.005). On the other hand, the flexural strengths of S3Z, D3P, and MIL groups were significantly higher than that of CON group (P<.05), but the flexural strength of D3Z group was significantly lower than that of CON group (P<.05). Conclusion: Within the limitation of our study, provisional restorative resins made from additive manufacturing showed clinically comparable fracture and flexural strength as those made by subtractive manufacturing and conventional method.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.25 no.10B
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• pp.1701-1706
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• 2000

In this work a 38 GHz hybrid 2-stage power amplifier module using GaAs pHEMTs and waveguide to microstrip transitions has been successfully developed. A 10 mil thickness duroid substrate was use for fabrication of the power amplifier and the waveguide to microstrip transitions. The fabricated waveguide to microstrip transition showed about 1 dB insertion loss(back to back) at 32-40 GHz. The measured results of power amplifier module showed 29 dBm output power(P1.5dB), 7,2 dB associated gain and 11.2% power-added efficiency(PAE) at 36.8-38.5 GHz.

• Journal of Power Electronics
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• v.9 no.4
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• pp.604-611
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• 2009

A dP/dV feedback-controlled MPPT (Maximum Power Point Tracking) method for photovoltaic power systems using II-SEPIC (Isolated Inverse-SEPIC; Single Ended Primary Inductance Converter) is presented and a current-mode dP/dV feedback-controlled MPPT method is devised to apply for the PV power converter system. A control strategy for the current-mode dP/dV feedback control system is developed in this paper and the proposed MPPT shows relatively satisfactory dynamics against rapidly changing insolation conditions. In order to verify the validity and effectiveness of the proposed method, simulations and experiments of the PV power system using II-SEPlC converter are performed. These simulation and experiment results show that the proposed method enables the PV power system to extract maximum power from the photovoltaic module against the solar insolation variation.