• Archives of Pharmacal Research
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• v.26 no.8
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• pp.644-648
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• 2003

To investigate the feasibility of developing a new ondansetron transdermal system, the effects of vehicles and penetration enhancers on the in vitro permeation of ondansetron hydrochloride (OS) from a pressure-sensitive adhesive (PSA) matrices across dorsal hairless mouse skin were studied. Vehicles employed in this study consisted of various ratios of propylene glycol monocaprylate (PGMC)-diethylene glycol monoethyl ether (DGME) co-solvents and PGMC-propylene glycol (PG) co-solvents with 3% oleic acid. $Duro-Tak^\circledR$ 87-2100 and $Duro-Tak^\circledR$ 87-2196 were used as PSAs. The concentration of DGME in PGMC-DGME co-solvent system affected the release rate; as the concentration of DGME increased, the release rate decreased. The cumulative release amount of OS increased as the ratio of PSA to drug solution decreased. The permeation flux was also primarily affected by the amount of PSAs; as the amount decreased, the permeation flux increased. The overall fluxes from matrix formulations were significantly lower when compared to those obtained from solution formulations. The ratio of PG to PGMC did not affect permeation flux, while the lag time decreased significantly from $5.14\pm3.31 to 0.31\pm0.12$ h as the PG increased from 40% to 60%.

• Transactions of the Korean Society of Automotive Engineers
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• v.19 no.1
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• pp.82-88
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• 2011

Lean combustion and exhaust emission characteristics in a ethanol fueled spark-ignited engine according to ethanol-gasoline fuel blending ratio were investigated. The test engine was $1591cm^3$ and 10.5 of compression ratio SI engine with 4 cylinders. In addition, lambda sensor system was connected with universal ECU to control the lambda value which is varied from 1.0 to 1.5. The engine performance and lean combustion characteristics such as brake torque, cylinder pressure and rate of heat release were investigated according to ethanol-gasoline fuel blending ratio. Furthermore, the exhaust emissions such as carbon monoxide (CO), unburned hydrocarbon (HC), nitrogen oxides ($NO_x$) and carbon dioxide ($CO_2$) were measured by emission analyzers. The results showed that the brake torque, cylinder pressure and the stability of engine operation were increased as ethanol blending ratio is increased. Brake specific fuel consumption (BSFC) was increased in higher ethanol blending ratio while brake specific energy consumption (BSEC) was decreased in higher ethanol blending ratio. The exhaust emissions were decreased as ethanol blending ratio is increased under overall experimental conditions, however, some specific exhaust emission characteristics were mainly influenced by lambda value and ethanol-gasoline fuel blending ratio.

• Journal of Korean Society for Atmospheric Environment
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• v.20 no.6
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• pp.739-748
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• 2004

A hybrid dust-collector combining a fabric filter with centrifugal force was developed to enhance the performance of the conventional fabric filter systems and its performances were evaluated to compare to that of the existing dust collector. The pressure drop rapidly increased with increasing the elapsed time and the face velocity in two filtration systems. But the increasing ratio of a hybrid dust-collector compare to the existing dust collector was lower. This results were confirmed from the performance such as cleaning interval, residual pressure drop and dust loading rate. The overall collection efficiency of the hybrid dust-collector was more than 99.6% and this showed a improvement of 0.6～2% than that of the existing dust collector. Especially, the fractional collection efficiency at the particle size of around 1${\mu}{\textrm}{m}$ is about 4% higher than that of the existing dust collector.

• Journal of ILASS-Korea
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• v.2 no.2
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• pp.24-34
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• 1997

This paper describes the investigation of combustion characteristics of gasoline-methanol blend in constant volume combustion chamber. A constant volume combustion chamber was used to elucidate a basic combustion characteristics and the premixer was installed to control temperature and equivalence ratio. And the maximum pressure, combustion duration and flame propagation according to the evaporation rate were measured to determine the optimal temperature range for evaporating a blend fuel. These experimental results indicate that the combustion characteristics such as combustion chamber pressure and combustion were deteriorated by decreasing surrounding temperature of fuel. These experimental results indicate that the combustion characteristics such as combustion chamber pressure and combustion were deter orated by decreasing surrounding temperature of fuel injected. It was also found that the overall gasification process for methanol blend fuel was influenced by a combustion chamber temperature rather than a premixer temperature.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.34 no.2
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• pp.200-211
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• 1998

Heat transfer performance improvement by fin and groovs is studied for condensation of R-11 on integral-fin tubes. Eight tubes with trapczodially shaped integral-fins having fin density from 748 to 1654fpm(fin per meter) and 10, 30 grooves are tested. A plain tube having the same diameter as the finned tubes is also used for comparison. R-11 condensates at saturation state of 32 $^{\circ}C$ on the outside tube surface coded by inside water flow. All of test data are taken at steady state. The heat transfer loop is used for testing singe long tubes and cooling is pumped from a storage tank through filters and folwmeters to the horizontal test section where it is heated by steam condensing on the outside of the tubes. The pressure drop across the test section is measured by menas pressure gauge and manometer. The results obtained in this study is as follows : 1. Based on inside diameter and nominal inside area, overall heat transfer coefficients of finned tube are enhanced up to 1.6 ~ 3.7 times that of a plain tube at a constant Reynolds number. 2. Friction factors are up to 1.6 ~ 2.1 times those of plain tubes. 3. The constant pumping power ratio for the low integral-fin tubes increase directly with the effective area to the nominal area ratio, and with the effective area diameter ratio. 4. A tube having a fin density of 1299fpm and 30 grooves has the best heat transfer performance.

• Journal of ILASS-Korea
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• v.24 no.4
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• pp.157-162
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• 2019

This numerical study was analyzed to predict the flammability limits of biodiesel and diesel fuels in the high temperature and pressure conditions. To achieve this, the biodiesel fuel was simulated with the chemical species of n-heptane (n-C₇H₁₆), methyl decanoate (C₁₁H₂₂O₂), and methyl-9-decenoate (C₁₁H₂₀O₂), and the diesel fuel was substituted the chemical species of n-heptane. The closed 0-D homogeneous reactor model which was employed the 1100 K of ambient temperature and 35 atm of ambient pressure was used for the simulation of constant volume combustion, and the equivalence ratio was changed from 0.3 to 2.5 conditions. In addition, a comparative analysis study was conducted with the results of HCCI engine simulation and flammability limits according to the changes of equivalence ratio. The results of combustion temperature, pressure, and ignition delay were increased when the equivalence ratio elevated from 0.3 to 1.3 conditions because the increase in fuel oxidation rate affects the chemical reaction of the overall combustion process. Furthermore, the CO and NO_X production under the rich combustion conditions are considered to have a trade off relationship since the OH radicals and O₂ chemical species are greatly affected the CO and NO_X production and oxidation processes.

• Journal of Community Nutrition
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• v.8 no.2
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• pp.63-68
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• 2006

This research analyzed the hematological index and health related habits such as alcohol drinking, smoking and exercise, by classifying 539 middle-aged men (age: 40 - 59) into a normal weight group, an overweight group and an obese group, according to BMI (body mass index). As a result, 33.6% (n = 181) of subjects had a BMI of 23 or less and 30.2% (n = 163) were overweight and 36.2% (n = 195) were obese (BMI > 25). The average systolic/diastolic blood pressures of total subjects were 130.96mmHg and 80.38mmHg, respectively. And the average pressure of normal subjects was 126.85/77.57mmHg, which was significantly lower than in overweight and obese subjects. Diastolic blood pressure shows significant differences among the three groups. The overall average cholesterol level of normal subjects was 193.81mg/dl, which was significantly lower than those in overweight subjects. Those in obese subjects were significantly higher than in overweight subjects. The GOT (glutamic oxaloacetic transaminase), GPT (glutamic pyrutic transaminase), ${\gamma}$-GTP (gamma-glutamyl transpeptidase) levels of obese subjects were significantly higher than in the overweight subjects. Frequency of alcohol drinking showed no significant difference among the groups. The smoking ratio in the obese group was higher than in the normal and overweight groups. The ratio of smokers was 53.1 %, and the alcohol drinking ratio was 81.0% of the total subjects. The frequency of drinking showed significant correlations with systolic blood pressure (p < 0.05) and diastolic blood pressures (p < 0.01) and ${\gamma}$-GTP (p < 0.01). The duration of smoking showed a negative correlation (p < 0.01) with diastolic blood pressure, total cholesterol and ${\gamma}$-GTP. On the other hand, exercising frequency showed negative correlations with blood glucose, ${\gamma}$-GTP and GPT(p < 0.01). These hematological indices were correlated with health related habits such as alcohol drinking, smoking and lack of exercise, and to be the cause of chronic diseases. Therefore, proper nutritional education is needed to establish advisable health related habits to maintain proper body weight. (J Community Nutrition 8(2): 63-68, 2006)

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.34 no.2
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• pp.212-222
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• 1998

Heat transfer performance improvement by fin and groovs is studied for condensation of R-11 on integral-fin tubes. Eight tubes with trapczodially shaped integral-fins having fin density from 748 to 1654fpm(fin per meter) and 10, 30 grooves are tested. A plain tube having the same diameter as the finned tubes is also used for comparison. R-11 condensates at saturation state of 32 $^{\circ}C$ on the outside tube surface coded by inside water flow. All of test data are taken at steady state. The heat transfer loop is used for testing singe long tubes and cooling is pumped from a storage tank through filters and folwmeters to the horizontal test section where it is heated by steam condensing on the outside of the tubes. The pressure drop across the test section is measured by menas pressure gauge and manometer. The results obtained in this study is as follows : 1. Based on inside diameter and nominal inside area, overall heat transfer coefficients of finned tube are enhanced up to 1.6 ~ 3.7 times that of a plain tube at a constant Reynolds number. 2. Friction factors are up to 1.6 ~ 2.1 times those of plain tubes. 3. The constant pumping power ratio for the low integral-fin tubes increase directly with the effective area to the nominal area ratio, and with the effective area diameter ratio. 4. A tube having a fin density of 1299fpm and 30 grooves has the best heat transfer performance.

• Journal of the Korean Society of Tobacco Science
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• v.18 no.2
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• pp.145-149
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• 1996

The experiment was carried out to study the effect of dry ice expanded tobacco (DIET) blending ratio on the physical properties of cigarettes. Vnencapsulated pressure drop (UPD) of the cigarette decreased from 85 mmWG to 78 mWG when the DIET blending ratio increased from 0% to 60%, but it increased in the range of over 60% blending ratio. But the overall UPD/EPD ratio of these cigarettes showed a decreasing tendency. Cigarette ventilation rate increased from 55% to 66% with the increased blending ratio of expanded tobacco and loose ends also showed the same tendency. The higher the blending ratio of expanded tobacco, the faster became the static burning time from 7' 34" to 5' 02". However, the cigarette hardness was almost not affected by the blending ratio.ing ratio.

• Journal of Advanced Marine Engineering and Technology
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• v.18 no.2
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• pp.91-96
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• 1994

Intake gases other than air, which is composed of oxygen, nitrogen, carbon dioxide, and argon, are used to study their effects on the performance of the diesel engine experimentally. The engine is operated at constant speed and fixed fuel injection timing, and cylinder pressure and heat release rate are measured at various intake gas compositions. The results show that increase of oxygen concentration improves the performance of the engine generally. The adverse effect is observed when the oxygen concentration is increased over the critical oxygen concentration of this test, mainly because of the over-shortened ignition delay. Increase of carbon dioxide concentration degardes the performance of the engine, mainly due to the lower specific heat ratio of carbon dioxide. Adding argon gas to the intake gas improves the overall performance. Finally, it is found that two most influencing factors affecting the performance of the diesel engine in this study are ignition delay and speific heat ratio of the intake gas.