• The Journal of Pediatrics of Korean Medicine
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• v.32 no.2
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• pp.26-42
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• 2018

Objectives The purpose of this study is to figure out the recent trend of the treatment for autism spectrum disorder (ASD) by comparing Korean and Chinese clinical studies. Methods National Digital Science Library (NDSL), Oriental medicine Advanced Searching Integrated System (OASIS), Research Information Sharing Service (RISS) and Korean Traditional Knowledge Portal (KTKP) were used to search Korean studies which were published from January, 2011 to May, 2017. Also Chinese National Knowledge Infrastructure (CNKI) and Wanfang data were used to search Chinese studies which were published from the same period. Key words of 'Autism' and 'Autism spectrum disorder' were used. Results 3 Korean studies and 21 Chinese studies were selected and analyzed to find out the most commonly used diagnostic criteria, treatments, including herbal medicine and acupuncture, and treatment assessment procedures. Conclusions As a result of comparing Korean and Chinese clinical studies for the treatment of ASD, both Korean and Chinese medicine treatments showed their effectiveness. However, there were some differences between two countries' clinical trends. In order for this study to be helpful, more highly evidenced clinical studies should be followed.

• The Journal of Pediatrics of Korean Medicine
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• v.36 no.3
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• pp.35-48
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• 2022

Objectives The purpose of this study is to review relevant clinical studies to investigate the effectiveness of herbal medicines for IgA (Immunoglobulin A) nephropathy in children. Methods Studies on herbal treatment for IgA nephropathy were searched and analyzed through electronic databases such as PubMed, EMBASE, China National Knowledge Infrastructure, Wanfang, CiNii, J-STAGE, Oriental Medicine Advanced Searching Integrated System and Science ON. Studies included Randomized controlled trials and case series. Results We selected nine studies and analyzed the findings. In most studies, improvement of IgA nephropathy was observed after treatment, and was evaluated using factors as 24 hour urine protein, hematuria, Scr (serum creatinine) and BUN (blood urea nitrogen). The most commonly used herbs for IgA nephropathy were Poria cocos (茯苓), Astragalus membranaceus (黃芪), and Rehmannia glutinosa (生地黃). Conclusions Based on the results of the clinical studies, we identified that herbal medicine is an effective treatment for IgA nephropathy. However, additional systematic clinical studies are necessary to prove its effect and safety.

• The Journal of Pediatrics of Korean Medicine
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• v.31 no.1
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• pp.1-11
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• 2017

Objectives The purpose of this study is to investigate commonly-used-pattern-identifications and to understand herbal medicine treatment for psoriasis based on recent clinical studies. Methods Keyword 'psoriasis' was used to search articles in National Digital Science Library (NDSL), Korean Traditional Knowledge Portal (KTKP), Oriental Medicine Advanced Searching Integrated System (OASIS) and Research Information Sharing Service (RISS). 19 relevant articles were reported between 2006 - 2016, and were obtained and reviewed. Results Among the 19 articles, the most commonly-used-pattern-identifications were 'blood heat pattern'. 'Gunsun-bang', 'Bangpungtongsungsan-gami'. Also, based on the search results, 'Yangdokbaekho-tang' were more frequently prescribed than other herbal medicines, and ingredients such as, Glycyrrhizae Radix (甘草), Saposhnikoviae Radix (防風) and Rehmanniae Radix (生地黃) were used repeatedly in those prescriptions. Conclusions This study showed what pattern identifications there are, and what herbal medicines are often used in clinical treatments. Developing new form of herbal medicines are also going to be possible with further research.

• Journal of Oriental Neuropsychiatry
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• v.33 no.2
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• pp.143-156
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• 2022

Objectives: The purpose of this study was to evaluate the quality of reporting for case reports published in Journal of Oriental Neuropsychiatry from year 2018 to 2021 compared with year 2013 to 2017 in order to recommend ways to improve the quality of case reports published in the future. Methods: To evaluate the quality of case reports identified by electronic searching in Oriental medicine Advanced Searching Integrated System (OASIS) and by hand searching from archives on peer review system of Journal of Oriental Neuropsychiatry using CAse REport (CARE) guideline. The researcher assessed the quality of reporting based on the CARE guideline as 'Sufficient', 'Not-Sufficient', 'Not-Applicable', and 'Not-Reported' for case reports published from 2018 to 2021 in Journal of Oriental Neuropsychiatry. In addition, it was compared with previous case reports published from 2013 to 2017. Results: Finally, 17 case reports were included for the assessment. General quality of reporting for case reports published from year 2018 to 2021 was improved compared with that of previous case reports published in 2018. The maximum value (46.4%→60.7%, 14.3% increase), the minimum value (22.2%→32.1%, 9.9% increase), and the median value (39.3%→50.0%, 10.7% increase) of the report rate evaluated as 'Sufficient' were generally improved. The maximum value (53.6%→50.0%, 3.6% decrease), minimum value (25.9%→21.4%, 4.5% decrease), and median value (35.7%→32.1%, 3.6% decrease) of the report rate evaluated as 'Not-Sufficient', the maximum value of the report rate evaluated as 'Not-reported' (40.7%→25.9%, 14.8% decrease), the minimum value (14.7%→10.7% decrease), and the intermediate value (14.7% decrease) were also generally improved. Four items (8b, 8d, 10c, and 13) were evaluated as 'Not-Reported'. These items seem to be items that need urgent improvement along with 8c, which showed a significant decrease in reporting rate. Conclusions: There are needs to improve the quality of case reports in Journal of Oriental Neuropsychiatry by comparing case reports published from year 2013 to 2017 with case reports published from year 2018 to 2021. To improve the quality of case reporting, sufficient education at the academic level should be provided on thesis preparation methods. It is also necessary to develop a tool for evaluating the quality of case reporting that reflects characteristics of Korean Medicine.

• Journal of Sasang Constitutional Medicine
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• v.30 no.2
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• pp.28-41
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• 2018

Objectives The purpose of this study is to evaluate the quality of case reports about Sasang Constitutional Medicine(SCM). Methods Case reports published from March, 2015 to March, 2018 in Journal of SCM were identified by searching from Oriental Medicine Advanced Searching Integrated System(OASIS). We assessed the quality of reporting of them based on CAse REport (CARE) guideline. Results A total of 39 case reports were finally included for the assessment. Overall quality of reporting was acceptable because case report even less reporting items mentioned 70.4% of them. However, the quality level was uneven because the maximum report rate was 77.8 %, the minimum 44.4 %, and the median 66.7 % when rigorously assessed. More than 50% of 39 case reports did not report 6 items about intervention adherence and tolerability, Diagnostic challenges, patient's perspective on interventions, informed consent, timeline, and adverse events, and did not sufficiently report 4 items about inclusion of terms such as case reports or SCM in keyword, symptoms of patient in abstract, information such as occupation relevant with psychosocial history, and the rationale for conclusions. Conclusions Efforts to improve the quality of reporting in SCM, and to develop case reporting guidelines appropriate for SCM are required.

• The Journal of Pediatrics of Korean Medicine
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• v.30 no.3
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• pp.52-60
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• 2016

Objectives The purpose of this study is to analyze studies about the effects of topical application of Chinese herbal medicine for allergic rhinitis within randomized controlled trials (RCT). Methods The search database includes KJTK (Korean Traditional Knowledge Portal), OASIS (Oriental Medicine Advanced Searching Integrated system), CNKI (China National Knowledge Infrastructure), PubMed, and EMBASE. We used the following key search terms: "allergic rhinitis", "traditional Chinese medicine", "traditional Korean medicine", "Chinese herbal medicine", "randomized controlled trial", "clinical study", "nasal spray", and "nasal drop" Results Five studies were selected for analysis. Three studies used nasal spray of Chinese herbal medicine and two studies used nasal drops of Chinese herbal medicine for the intervention. Frequently used herbs were Magnoliae Flos (辛夷), Scutellariae Radix (黃芩), Coptidis Rhizoma (黃連), and Astragali Radix (黃芪). For the outcome measures, studies used symptom score, questionnaire of Quality of Life, nasal airway resistance, or laboratory studies. From all 5 studies, it has been shown that topical application of Chinese herbal medicine was effective for improving symptoms of allergic rhinitis. Two out of five studies showed statistical difference between study group and control group. Conclusions This study shows that topical application of Chinese herbal medicine can improve symptoms of allergic rhinitis. Well-designed RCT studies with low risk of bias and studies with outcome measures for assessing the immunomodulatory effects are necessary to confirm these findings.

• The Journal of Korean Medicine
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• v.41 no.4
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• pp.78-87
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• 2020

Objectives: In modern society, many people have low back pain (LBP) and spinal diseases. About 80% of them experience severe LBP more than once in their lifetime. We can find studies on many Korean medicine-based treatments, such as acupuncture treatment for LBP and exercise therapy, which are effective in reducing the symptoms. This study focuses on the combined effect of both Korean medicine and exercise therapy for treating LBP. Method: For this review, we searched for articles focusing on pain and disability recovery in pre-clinical and clinical studies of extension and flexion exercise therapy related to LBP. The search databases were as follows: PubMed, Google Scholar, and seven Korean electronic databases (Korea Citation Index (KCI), Korean studies Information Service System (KISS), Research Information Service System (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), DBPIA, National Digital Science Library (NDSL), and KOREAMED). The keywords were as follows: Korean Medicine, back pain, flexion exercise, extension exercise, McKenzie method, McKenzie exercise, Williams' flexion exercise, and Mechanical Diagnosis and Therapy. Results & Conclusions: This review shows the usefulness of flexion and extension exercises for LBP treatment and effective patient education, but further studies are necessary.

• Journal of Acupuncture Research
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• v.41 no.2
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• pp.75-86
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• 2024

A review of randomized controlled trials (RCTs) using electroacupuncture (EA) to treat patients with foot drop was performed to analyze the effectiveness of EA for this condition. Relevant studies (n = 183) from 7 databases (Cochrane Library, Excerpta Medica Database, PubMed, China National Knowledge Infrastructure, Korean Studies Information Service System, Research Information Sharing Service, and Oriental Medicine Advanced Searching Integrated System) were selected based on the inclusion and exclusion criteria, and 12 RCTs met the selection criteria. In all 12 studies, EA showed significantly positive changes. In most indicators, positive changes were observed in the EA group compared with that in the control group. Significant increases were confirmed in muscle strength-related indicators such as the Fugl-Meyer motor scale, surface electromyography, active range of motion, and gait-related indicators such as the Tinetti score, maximum walking speed, and Berg balance scale. No notable adverse events were reported. EA is suggested as an effective treatment for post-stroke foot drop; however, more RCTs are required.

• Journal of Korean Medicine Rehabilitation
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• v.33 no.4
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• pp.45-59
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• 2023

Objectives The aim of this study was to analyze the trends of researches on oriental medicine treatments for supraspinatus tendinopathy. Methods We used five databases for searching researches; Korean studies Information Service System, Oriental Medicine Advanced Searching Integrated System, Research Information Sharing Service, PubMed, and China National Knowledge Infrastructure. Only randomized controlled trials suitable for the subject were selected. The methodological quality of included randomized controlled trials (RCTs) was assessed by the Cochrane risk of bias tool. Results Twenty randomized controlled trials were analyzed. There were 9 types of treatment interventions; acupuncture, acupotomy, pharmacopuncture, electroacupuncture, fire needling, warming needle, catgut-embedding therapy, herbal medicine, cupping. The most frequently used treatment intervention was acupuncture and acupotomy. There were 9 outcome measurements including visual analog scale (VAS), Constant-Murley Score (CMS), and range of motion. The most used measurement was VAS. As a result of meta-analysis, acupuncture was more effective than control group in VAS. Additionally, acupotomy was clinically significant compared to control groups in VAS and CMS. Conclusions In this review, we analyzed researches on effectiveness of oriental medicine for supraspinatus tendinopathy. A provisional conclusion can be produced that acupuncture and acupotomy showed beneficial effect to supraspinatus tendinopathy. Although there were some RCT studies, many of them had a high risk of bias, so it is hard to conclude that our study can include overall clinical status. Further well-designed trials are needed.

• The Journal of Korean Obstetrics and Gynecology
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• v.36 no.3
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• pp.129-153
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• 2023

Objectives: The purpose of this study is to report the clinical effectiveness and safety of herbal medicine treatment for postmenopausal osteoporosis. Methods: Researchers searched papers through 5 online databases including The Cochrane Library Central, Pubmed, China Academic Journal (CAJ), Oriental medicine Advanced Searching Integrated System (OASIS) and Korean studies Information Service System (KISS). Randomized controlled trials (RCTs) that used herbal medicine as treatment were included. Results: Twenty three studies were selected by the selection and exclusion criteria. The treatment group was treated with herbal medicine alone or with herbal medicine and conventional medicine. The control group was treated with conventional medicine. Most common evaluation index was Bone Mineral Density (BMD) followed by total efficacy rate and level of bone metabolism markers, level of sex hormones, etc. Compared with the control group, the treatment group was more effective and safer in all of 23 studies. Conclusions: Herbal treatment alone could be an effective and safe option in treating postmenopausal osteoporosis. Moreover herbal treatment with conventional medicine could improve its therapeutic effect on postmenopausal osteoporosis as well.