• 제목/요약/키워드: Oriental Medicine Prescription

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아토피 피부염 외치치료제 처방 개발을 위한 실험적 연구 (An experimental study for the development of prescription on atopic dermatitis)

  • 김건우;박지원;심부용;김동희
    • 대한본초학회지
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    • 제29권4호
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    • pp.13-20
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    • 2014
  • Objectives : Atotang was composed of 10 kinds of traditional medicinal herb. This research was performed to examine biological effects of Atotang for the development of prescription on atopic dermatitis. Methods : Atotang was extracted with 80% EtOH. Free radical scavenging assay has tested for anti-oxidative activity as well as the contents of total polyphenol. We observed the production of ROS, nitric oxide(NO) and the inflammatory cytokines such as interleukin-1beta(IL-${\beta}$), IL-6, tumor necrosis factor-alpha(TNF-${\alpha}$), Prostaglandin E2($PGE_2$) in Raw 264.7 cells stimulated by LPS. We used Disc diffusion method to investigate antibacterial activity on Candida albicans, Staphylococcus aureus and Staphylococcus epidermis. Result : Content of total phenolic compound of Atotang was 36.3 mg/g ext. DPPH and ABTS scavenging activities were 77% and 46% at 200 ug/ml respectively, showing dose-dependent increase. The amounts of ROS and NO in RAW 264.7 cells were decreased by 30% and 19% at 200 ug/ml, respectively, showing dose-dependent decrease. The prodcution of IL-1beta, IL-6 and TNF-alpha in RAW 264.7 cells were decreased dose-dependently by 81%, 67%, and 20% at 200 ug/ml, respectively. Atotang was reduced LPS-stimulated production of $PGE_2$ by 33%. Atotang on C. albicans, S. aureus and S. epidermis was selected by a disc diffusion method and inhibition effect of the Atotang on the growth of S. epidermis was the greatest. Conclusion : The results indicated that Atotang showed biological activities showing anti-oxidant, anti-inflammatory and antibacterial effects. Based on these results, it is concluded that Atotang can be applied to the prescription on atopic dermatitis.

소음인(少陰人) 약방(藥方)의 형성과정에 관한 연구(硏究) (The study on the formative process of Soeumin prescription)

  • 박성식;배효상
    • 사상체질의학회지
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    • 제14권1호
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    • pp.10-25
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    • 2002
  • 1. Purpose This Study is intended to catch the expasion of theory of Sasang Constitutional Medicine through comparision DongyiSooseBowon Chopanbon with DongyiSooseBowon Chobonguen and DongyiSooseBowon Gabobon. 2. Method I compared the Soeumin's prescriptions and medications of DongyiSooseBowon Chopanbon with those of DongyiSooseBowon Chobonguen and DongyiSooseBowon Gabobon. 3. Result and conclusion 1. The Soeumin's meducations used in the prescriptions of chobonguen are 44 and those of Gabobon are 47, those of chopanbon are 46 2. Soeumin;s Medications of the same kind in Chobonguen's precriptions and Gabobon's and Chopanbon's are twenty-five;like Daejo(大棗), Jinpi(陳皮), Gamcho(甘草), etc. and these medications are the princople in soeumin's disease. 3. Soeumin's Prescriptions of the same name in Chobonguen's prescriptions and Gabobon's and Chopanbon's are two;Gwakhanggeunggisan(藿香精氣散) and Bogungikgitang(補中益氣湯). These two prescriptions are correspond to the prescriptions those were recorded in Song-won-myuong Soeumin's princple prescription of experience(宋元明 少陰人經驗行用要藥). 4. Soeumin's Prescriptions of the same name in Chobonguen's precriptions and Gabobon's are two;Gwakhanggeunggisan(藿香精氣散) and Bogungikgitang(補中益氣湯). Chobonguen's precriptions were composed of Old prescriptions(古方) except the medications those were considered of wrong Sang Constitutional medications. 5. Soeumin's Prescriptions of the same name in Gabobon's prescriptions and Chopanbon's are nine and except Padudan(巴豆丹) have differences in the kind of medications and quantites. This fact shows that Dongmu(東武) roform the Sasnag Constitutional prescriptions continuously. 6. As this, Dongmu(東武) selected Sasang Constitutional prescription and medication in detail as he has the more experince of treatment.

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방풍통성산(防風通聖散)의 문헌(文獻) 및 형상의학적(形象醫學的) 고찰(考察) (Documentational Study and Observation from the View of Hyungsang Medicine on Bangpungtongseong-san)

  • 석민희;김준홍;이용태
    • 동의생리병리학회지
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    • 제22권1호
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    • pp.51-59
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    • 2008
  • The following conclusions were obtained from the studies on Bangpuntongseongsan both from the documents and Hyungsang medicine. Bangpungtongseong-san was created by Yu Wan-so to relieve both interior and exterior of disease from the pathogenic fire, and it cures wind syndrome and dry syndrome. Bangpungtongseong-san is of light herbal combination and it works in the upper part of the body and is mainly applied to skin disease. Perspiration without harming the exterior and purgation without hurting the interior shows that it is not a severe prescription belonging to meditation therapy. It is mostly used for curing the disease of internal heat caused by over drinking and consuming heavy food, and it has special relationship with Yangmyung meridian. It is mentioned in the chapters of spirit, head, face, eye, ear, nose, throat, skin, hair, prescription, wind, dryness, fire, internal damage, epidemic infectious disease, carbuncle and cellulitis, ulceration, and pediatrics of ${\ulcorner}$Donguibogam${\lrcorner}$. It is usually applied to those who belong to Yangmyung type of the six meridian types or wind type, who has excessive heat, people with red complexion, reddened nose, pimples over the face and nose, coarse heel, loss of hair due to wind-heat, and to those who tend to have dandruff. Through examination over the cases treated with Hyungsan medicine, Bangpungtongseong-san was found efficacious in bloodshot eyes, brandy nose, loss of hair, various skin problems, tetanus, acute alcoholism, paralysis of hand and foot, deafness, and tinnitus.

동의보감(東醫寶鑑) 중(中) 형개(荊芥)가 주약(主藥)으로 배오(配伍)된 방제(方劑)의 활용(活用)에 대한 고찰(考察) (The Applications of Herba Schizonepetae Mainly Blended Prescription in Dongeuiboga)

  • 임대환;전영균;김원채
    • 대한한의학방제학회지
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    • 제17권2호
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    • pp.21-38
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    • 2009
  • This report describes 86 prescriptions related to the use of Herba Schizonepetae main blended from Dongeuibogam. The following conclusions were drawn through investigations on the prescriptions that use Herba Schizonepetae as a key component. Prescriptions that Herba Schizonepetae was taken as a monarch drug are utilized for22 therapeutic purposes, for example, eye disease, abscess disease, head and tooth, and woman disease. In particular, 16.3% of prescriptions appear in the chapter of eye. Prescriptions that utilize Herba Schizonepetae as the main component are used in the treatment of eye, abscess and woman disease, head disease, tooth disease and they are also used for treating 56 different types of disease. Herba Schizonepetae is used in pathogenic factors such as wind and used in pathology related to the liver and stomach system. The dosage of Herba Schizonepetae is 1pun 3li(about 0.49g) to 4don(about 14g), however 5pun 3li(about 1.99g)~1don(about 3.75g) has been taken the most for clinical application. Bangpungtang and Saenglyosamultang are the most useful base prescriptions which use the Herba Schizonepetae as the main ingredient.

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조선후기(朝鮮後期) 상한(傷寒) 연구(硏究)의 일면(一面) - 조선후기(朝鮮後期) 상한(傷寒) 연구서(硏究書) "상한경험방요촬(傷寒經驗方要撮)"의 구성과 내용 - (Composition and Contents of the Monograph on Theory of Cold Damage - "Sanghankyeongheombangyochal"(傷寒經驗方要撮) in the Late Joseon Dynasty)

  • 오준호;박상영;김현구;권오민
    • 한국한의학연구원논문집
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    • 제18권1호
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    • pp.25-34
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    • 2012
  • Objective : This study was carried out with focus on written by Joh, Taek-seung (曺澤承) and Joh, Byeong-who(曺秉矦) in the relation of father and son in 1933. This book is a medical book including rare data, which has never been reported to academic circles all this while. Method : First, this study looked into the authors of this book and its history of publication. Further, this study analyzed the composition and contents of this book. Lastly, this study summed up the meaning of this book from the standpoint of medical history. Result : The authors were Confucian doctors who were active in the latter era of the Joseon Dynasty and also in the period of Japanese colonial rule. They lived in Haenam district of Jeonlanam-do, and cured its neighboring local residents while studying. They published the book of by putting together their own medical experiences. The authors suggested their remedial prescription according to gender and age whereas Zhang Zhongjing(張仲景) suggested the remedial prescription according to Six-Meridian Pattern Identification & Syndrome Differentiation(六經辨證). In addition, the authors of gave weight to the relationship with internal damage. Additionally, the authors not only thought much of the relationship between internal damage and external damage but also thought of the weakness and strength of the healthy qi, and the new and the old of a disease as an important clue to medical treatment. It seems that such contents was influenced by (東醫寶鑑). Conclusion : shows the results of the research on which was spontaneously conducted in Joseon.

Effect of the Geijibokryunghwan on human hepatocarcinoma cells

  • Lee Soo Kyung;Kim Han Geu;Ahan Jong Chan;Chung Tae Wook;Moon Jin Young;Park Sun Dong;Kim June Ki;Choi Dall Yeong;Kim Cherl Ho;Park Won Hwan
    • 동의생리병리학회지
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    • 제17권2호
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    • pp.568-573
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    • 2003
  • We invesgated the GBH water extracts can be used as a potential cancer chemopreventive agent in humans, especially in hepatological cancer cell lines. The GBH was found to act as an potent inhibitor of COX-I only, but not as COX-2 inhibitor. Furthermore, the extract mediated anti-inflammatory effects and inhibited COX-associated hydroperoxidase functions(antipromotion activity). Inhibitory effect of the GBH water extracts on the growth of cancer cell lines such as HepG2 cell and Hep3B cell was shown.

시호사물탕이 t-BHP로 유도된 간세포의 산화적 손상 및 자유기에 의한 지질과산화 반응에 미치는 영향 (Preventive Effects of Sihosamultang Extract on Lipid Peroxidation by Free Radicals and Oxidative Damage of Hepatocytes by tert-Butyl Hydroperoxide)

  • 김태기;박선동;문진영
    • 대한한의학방제학회지
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    • 제8권1호
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    • pp.241-255
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    • 2000
  • Sihosamultang(SST) has been used for the treatment of puerperal fever, liver disease in traditional medicine. The present study was carried out to evaluate the antioxidant effects of SST extract in vitro. The inhibitory effect of SST extract on lipid peroxidant was examined in the linoleic acid autoxidation system. In this test, SST extract significantly inhibited the time course of the lipid peroxidation. And SST extract showed about 73% scavenging effect on DPPH radical. And this extract inhibited not only the lipid peroxide formation induced by hydroxyl radical derived from $ H_{2}O_{2}-Fe^{2+}$ in the rat liver homogenate, but also the superoxide generation from xanthine-xanthine oxidase system in a dose-dependent manner. In addition, SST extract protected the hepatic cell death induced by tert-butyl hydroperoxide. These data indicated that SST might play a protective role against oxidative injury by free radicals.

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골다공증의 연구 경향에 대한 고찰 -한의 학술 논문 검색을 중심으로- (The Review on the Study of Osteoporosis in Oriental Medicine Journals)

  • 김영욱;송윤경;임형호
    • 대한추나의학회지
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    • 제5권1호
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    • pp.67-76
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    • 2004
  • Objectives : The purpose of this study is to research trends In the study of osteoporosis and to establish the future direction for its study. Methods: We reviewed oriental medicine papers published in last twelve years (1990-2002). Methods : We reviewed oriental medicine papers published in last twelve years (1990-2002). Results : 1. We researched 42 papers in 12 journals and patterns of study were as follows: experimental studies were 30 (71%), reviewed studies were 8(19%), clinical studies were 2 (5%) and etc were 2 (5%). 2. The experimental studies(30) were divided into papers on efficiency testing of herbal medications (22) and herbal acupuncture (7) and etc (1). 3. The reviewed studies showed that research has been carried out in the fields of cause, pathogenesis, principles for treating disease, herbal medication, herbal acupuncture, acupuncture and moxibustion, exercise to osteoporosis. 4. The clinical studies showed that the research was carried out in the fields of follow up surveys for the herbal medication efficiency testing, the relativity of osteoporosis to other diseases. 5. In consequence of researching the case reports, there was no prescription used meaningfully. Conclusions: We need more studies of osteoporosis by reaching for specific therapy.

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불안(不安) 및 불안병증(不安病症)에 대한 한의학적 연구 (A Bibliographic Study of Anxiety and Anxiety Disorder in Oriental Medicinee)

  • 권종준;김태헌;류영수;강형원
    • 동의신경정신과학회지
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    • 제16권1호
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    • pp.159-169
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    • 2005
  • Anxiety is essentially a normal emotion with great adaptive significance like pain. to ease human suffering, treatment is sought to quell pain and anxiety only when they are excessive or when they interfere with performance or general health. In oriental medicine, anxiety has been also known as a important factor which is cause of body and mind disease. We obtained some points after studying of bibliographic research about anxiety and anxiety disorder like follows: 1. The signification of anxiety is similar to fear affection(恐情) and anxious feelings are fearful, long for solitary life and afraid of captivity. 2. Mechanism of anxiety disorder is related with kidney(腎) as well as heart(心), liver(肝), gall bladder(膽) and stomach(胃). 3. The prescription of fear affection is tonifying of kidney(益腎) and fixing of kidney's pure substance(固精) that is based on deficiency of kidney(賢氣不足) 4. A representative disorder about anxiety and phobia are Keongke(驚悸) and Cheongchung(정충). 5. Keongke(驚悸) and Cheongchung(정충) may be understood as phobias(恐佈症), general anxiety disorder(凡不安障碍) and panic disorder(恐慌障碍).

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징하에 응용(應用)되는 귀출파징탕과 가미귀출파징탕의 효능(效能)에 관(關)한 연구(硏究) (Studies on the Effect of Guichoolpajing-Tang and Gamiguichoolpajing-Tang)

  • 송석호;송병기;이경섭
    • 대한한방종양학회지
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    • 제1권1호
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    • pp.213-230
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    • 1995
  • The present work was done to investigate the pharmacological effectiveness of Guichoolpajing-Tang and Gamiguichoolpajing-Tang. The extracted water of those two prescription were administered to experimintal animals and determined analgesic, anti-pyretic, anti-inflammatory effects and effects on intravascular coagulation, spontaneous morements of the isolated rat uterus, the uterine contracion induced by oxytocin or $PGF_{20}$, lifespan of mice implanted intraperitoneally with Sarcoma 180. The following results were obtained. 1) The extracted water of Guichoolpajing-Tang and Gamiguichoolpajing-Tang were revealed significant analgesic effect. 2) The extracted water of Guichoolpajing-Tang and Gamiguichoolpajing-Tang showed anti-pyretic effect. 3) The extracted water of Guichoolpajing-tang and Gamiguichoolpajing-Tang showed anti-inflammatory effect. Especially, the extracted water of Gamiguichoolpajing-Tang showed more significant dffect than another. 4) Concerning the degree of concentration of FDP, Gamiguichoolpajing-Tang treated groups tevealed significant decreases. 5) The extracted water of both prescriptions revealed uterus relaxation on the spontaneous movement of the isolated rat uterus and showed uterine contraction induced by oxytocin or $PDF_{2}$. Especially Guichoolpajing-Tang showed more significant effect than another. 6) The extracted water of both prescription both prescriptions showed effect on lifespan of mice implanted intraperitoneally with Sarcoma 180.

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