[KSCI] Korea Science Citation Index Service

Effect of the Geijibokryunghwan on human hepatocarcinoma cells

Lee Soo Kyung (Department of Diagnostics, College of Oriental Medicine, Dongguk University)
Kim Han Geu (Department of Diagnostics, College of Oriental Medicine, Dongguk University)
Ahan Jong Chan (Department of Diagnostics, College of Oriental Medicine, Dongguk University)
Chung Tae Wook (Department of Diagnostics, College of Oriental Medicine, Dongguk University)
Moon Jin Young (Department of AM-Pointology, College of Oriental Medicine, Dongguk University)
Park Sun Dong (Department of Prescription, College of Oriental Medicine, Dongguk University)
Kim June Ki (Department of Pathology, College of Oriental Medicine, Dongguk University)
Choi Dall Yeong (Department of Pathology, College of Oriental Medicine, Dongguk University)
Kim Cherl Ho (Department of Biochemistry, College of Oriental Medicine, Dongguk University)
Park Won Hwan (Department of Diagnostics, College of Oriental Medicine, Dongguk University)

Publication Information

Journal of Physiology & Pathology in Korean Medicine / v.17, no.2, 2003 , pp. 568-573 More about this Journal

Abstract

We invesgated the GBH water extracts can be used as a potential cancer chemopreventive agent in humans, especially in hepatological cancer cell lines. The GBH was found to act as an potent inhibitor of COX-I only, but not as COX-2 inhibitor. Furthermore, the extract mediated anti-inflammatory effects and inhibited COX-associated hydroperoxidase functions(antipromotion activity). Inhibitory effect of the GBH water extracts on the growth of cancer cell lines such as HepG2 cell and Hep3B cell was shown.

Keywords

Geijibokryunghwan; hepatocarcinoma chemoprevention cyclooxygenase (COX);

Citations & Related Records

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