• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2018년도 추계학술대회
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• pp.127-127
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• 2018

Probiotics are microorganisms that have beneficial effects on the health of the host. The health promoting effect by probiotics influences suppressing harmful bacteria, prevention of constipation, blood cholesterol reduction and regulation of blood pressure. Prebiotics are used to promote the growth or activity of microorganisms. Synbiotics, which are a mixture of probiotics and prebiotics, synergize in the intestines by complementing each other. Synbiotics not only improves the viability of the probiotics while passing through the gastrointestinal tract, maintain intestinal homeostasis, but also regulate balance of harmful and useful bacterial growth. Glycine max Merr (GMM) has been widely used in Asian countries to treat cancer, obesity, oxidative stress and imbalanced immune diseases. In addition, it has been reported that dietary fiber-rich grains promote bowel movements and prevent constipation. In this study, we investigated the viability of LactobacillIus buchneri (L.buchneri) strains, known as lactic acid bacteria under conditions of gastric fluid and intestinal fluid to determine the suitability of L.buchneri as probiotics. The adhesion ability of L.buchneri to caco-2 cells was also confirmed. The present studies showed that GMM extract promoted the growth and activity of L.buchneri strains as prebiotics. Also, this results suggested that the mixture of L.buchneri and GMM extract can helps maintain intestinal health and healthy body as synbiotics and health functional food material.

• 대한한의학회지
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• 제31권1호
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• pp.1-13
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• 2010

Objective: Functional dyspepsia is a prevalent disease. It impedes subjective quality of life. The purpose of this study was to examine the equivalent effect of herb medicine treatment (DA-9701) for functional dyspepsia. Methods: In this randomized, single-blinded, placebo-controlled study, we compared a herb medicine (DA-9701) with standard treatment (mosapride) and placebo for the treatment of functional dyspepsia. 42 volunteers who satisfied the requirements were enrolled in study. Severity of dyspepsia was measured by Nepean Dyspepsia Index (NDI) and Functional Dyspepsia Quality of Life (FD-QOL) before and after treatments. Results: 1. In the DA-9701 group, total key symptoms score was significantly lower and improve rate of key symptoms was higher than in the mosapride and placebo groups, but there were no statistically significant differences between three groups. 2. In the DA-9701 and mosapride groups, "nausea" and "bad breath" were significantly lower compared with the placebo group. 3. In the DA-9701 group, NDI Quality of Life scores were significantly higher, but there were no [other] statistically significant differences between the three groups. 4. In the DA-9701 and mosapride groups, FD-QOL scores were higher compared with the placebo group, but there were no statistically significant differences between the three groups. Conclusion: Herb medicine treatment (DA-9701) is effective to improve the symptoms and quality of life in patients with functional dyspepsia.

• 혜화의학회지
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• 제15권1호
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• pp.71-78
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• 2006

Objective : The purpose of this study is to report to treat two patients who had symptoms on head and face because of stress. Methods : The changes in symptoms of heat on right bucca, spasm of upp. er lip, left parietal pain, in individual expression were described as they were treated with acupuncture therapy named An-sim-bang(安心方), moxibustion and herb medicine. Results : Symptoms of heat on right bucca, spasm of upp. er lip, left parietal pain at admission improved and disapp eared gradually with acupuncture therapy named An-sim-bang(安心方), moxibustion and herb medicine. The patients could discharge with favorable recovery. Conclusion : In oriental medicine, stress is mainly treated by taking down flaring-up of heart fire, removing depression of Ki and fulling up deficiency of Yin of the kidneys. We experienced that these treatments by acupuncture therapy named An-sim-bang(安心方), moxibustion and herb medicine have the effect treating symptoms on head and face because of stress.

• 대한한의학회지
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• 제17권2호
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• pp.73-87
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• 1996

Erectile dysfunction is defined as the inability to attain and maintain penile rigidity sufficient to allow sexual intercourse. Although erectile dysfunction is usually considered a benign disorder, it has a dramatic impact on quality of life of the patients as well as their sexual partners. And it is common in men between the age of 40 and 70 years, and its incidence increases with age. The prevalence is reported to occupy 10% at the age of 40 years, 20% in 50s, 30% in 60s and 50% at the age of 70 years, and is more prevalent as stress in modern life and interest onsexual behavior increase. This article has aims to investigate and summarize the current trend of treatment for erectiledysfunction so as to suggest the effective and available way to treat the disease. In oriental medicine, erectile dysfunction has been treated with herb medicine and acupuncture with good results. Some of herb drugs have the substances which induce penile erection. So it should be investigated on the neurotransmitter or endothelial mediator which can be included in herb drugs. The acupuncture therapy stimulates the erectile nerves and is reported to be effective for erectile dysfunction. And suppository, locus injection therapy and topical agent are found to be effective as well as stellate ganglion block and biofeedback treatment. So the study on the approach and application of these treatments on erectile dysfunction would be necessary.

• 대한한방소아과학회지
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• 제18권2호
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• pp.127-142
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• 2004

Objective : To evaluate the effect of Oriental medical treatment on a patient with Ramsay Hunt syndrome with poor prognosis on EMG. Methods : We applied various methods of Oriental Medical treatment including Acupuncture, Electroacupuncture, Herb medicine, Vesiculation therapy using Mylabris and Crontonis Fructus, Massage, Self-excercise of face muscles. Results : 1. Herb medicine was applied on the basis of Differentiation of Syndromes(辨證): We tried Herb medicine to improve the function of Digestive System. The patient's stool condition, subjective sensation related with abdominal pain and general condition improved. 2. We used the Vesiculation therapy using Mylabris which was used traditionally to treat Facial Palsy. We powdered Mylabris and mixed it with Crontonis Fructus to make a paste. We put it on Ye-poong(?風), Nae-gwan(內關) at left side. It induced vesicles at the applied area, but it disappeared in 48 hours without any scar. 3. We applied acupuncture, electroacupunture, massage and self-excercise of face muscles. On gross scale assessment, there was some improvement. And assessment with regional scale also showed changes. The patient and the guardian were satisfied with the result. Conclusion : We experienced a case of Ramsay Hunt syndrome with poor prognosis on EMG. She also showed poor response to conservative treatment. Through various modalities of Oriental medical treatment, we attained some clinical improvement.

• 생약학회지
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• 제46권4호
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• pp.321-326
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• 2015

The prevalence of diabetes mellitus continues to rise alarmingly because of industrialization of society. The aim of this study was to investigate the antidiabetic effects of black ginseng extract (BGE) which was performed panax ginseng. First we examined the inhibitory effects of BGE on ${\alpha}$-glucosidase. But there was no practical effects in our observations. We, also, investigate the effects of BGE on glucose uptake of skeletal muscle using 2-NBDG in $C_2C_{12}$ myotube. BGE significantly improved the glucose uptake considered as a lowered blood glucose level. Effects of GBG05-FF on fasting blood glucose and glycated hemoglobin (HbA1c) were investigated in streptozotocin (STZ)-induced diabetic mouse. After injection of STZ, fasting blood glucose and glycated hemoglobin rapidly increased. But STZ-induced diabetic mouse treated with GBG05-FF significantly reduced the level of fasting blood glucose and HbA1c. This results showed that supplementation of BGE improve the diabetic parameters and BGE have a potentiality as a functional food for Diabetes mellitus.

• Journal of Acupuncture Research
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• 제18권5호
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• pp.11-23
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• 2001

Objective : This study is designed to evaluate the clinical effect of the oriental medical treatment (Ex: chuna, physical theraphy, acupuncture, moxibustion, herb medicine, etc.) on patient of scoliosis. Methods : We investigated 12 patients with scoliosis who visited to Department of Acupunture & Moxibustion, Tae gu Oriental Hopital of Kyung San University from January 2000 to September. 12 patients had a diagnosis of scoliosis by X-ray. We treated 12 patients by the oriental medical treatment (Ex: chuna, acupuncture, physical theraphy, moxibustion, herb medicine, etc.)and they were evaluated with post treatment X-ray findings. Results : 1. We investigated 6 female and 6 male patients. The most commom distribution of age was 30's. 2. In the scoliosis angle : before treatment, the average scoliosis angle was $13.56^{\circ}$ but after treatment, it was decreased to $9.31^{\circ}$ and the mean correctability was 33.47%. 3. The more servious the symptoms were, the lesser the correction rate was. It was decreased in the order of Gr I, Gr II, Gr III and Gr IV. 4. The larger the scoliosis angle and the degree of rotation were, the lesser the correction rate was. Conclusion : These results suggest that the oriental medical treatment (Ex: chuna, acupuncture, physical theraphy, moxibustion, herb medicine, etc.) was effective treatment modality on patient of scoliosis.

• 한방안이비인후피부과학회지
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• 제27권4호
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• pp.189-199
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• 2014

Objective : The purpose of this study is to report the efficacy of using oriental medical treatment(herb-medicine, acupuncture) with Melonix Calyx Vomiting Therapy for atypical facial pain. Methods : We experienced two cases of atypical facial pain treated with oriental medical treatment(herb-medicine, acupuncture) and Melonix Calyx Vomiting Therapy(MCVT). MCVT is a traditional treatment, which induces vomiting by eating Melonix Calyx powder with water. To evaluate the results of this treatment, we used the Visual Analogue Scale(VAS) and Pain Rating Scale(PRS). Result : After using MCVT with oriental medical treatment, VAS, PRS and clinical symptoms of 2 patients were improved remarkably. Conclusion : This study suggests that using MCVT with oriental medical treatment is effective on atypical facial pain.

• 대한예방한의학회지
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• 제1권1호
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• pp.126-136
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• 1997

To procide basic data for improvement of oriental medical care system, the questionnaire interview was carried out with community peoples, over 20 years old, selected randomly in Seoul, Pusan, Taegu and Taejon err. from 10th Mar. to 20th Apr. 1996. The result were summarized as follows: 1. In the general characteristics of subjects, the highest portion of each part was 52.4% of male, 22.4% of thirties, 37.1% of college graduates, 19.1% of married, 30.6% of town dwellers, 63.3% of muddle social class, 26.6% of housewife, 19.3% of student, 16.6% officer and 11.6% of professional technician. 2. The portion of subjects agree to open oriental clinic in western medicine hospital was 60.0%, that of disagreement was 20.1%, Among 60.0% of agreement group, the high rate was showed in female, fifties, middle school graduates, unemployed, middle social level. 3. The rate of positive responses in system of a herb specialist was 64.7%, that of negative responses was 11.6%. Among positive responses, the groups of high rate were male. twenties, above college graduates, student, middle-high social level and city dwellers. 4. In the question whether a pack of herb medicine should be included in medical insurance or not, the rate of agreement was 74.3%, that of disagreement was 4.1%. Amount agreement subjects, the high rate was showed in male, young age, high educated, city dwellers, professional technician middle social class. 5. In the cost of oriental medical care, the portion was divided by 70.3% of expensiveness,25.6% of moderate, 4.1% of low price. among 70.3% of high price, the high rate was in female, forties, agrolivestock-fishery, and town dwellers. 6. In the question what the herb doctor should do for the improvement of oriental medicine, the highest rate was 54.2% in further study. The next was 23.0% in need of western medical and 9.1% in no complain in present situation. Among 54.2% of further study, the high rate was showed in male, forties, high school graduate, profession technician, high social level, christian, married and city dwellers. 7. About institution of oriental care, 86.8% of subjects answered to need of improvement, 8.0% of them replied no problem as present. Amount 86.8% of subjects, the high rate was showed in male, twenties, above college graduate, sales, singles, high social level and city dwellers. 8. About necessity of western medical care instrument in oriental medical hospital, the rate of sightly need was 47.5%, inevitably need was 37.7%, no need was 6.3%, the Positive subjects were showed high rate in male, officer, singer, the younger age, the higher educated, better social level and city dwellers. These results might be useful information for establishing of oriental medical care policies, which open oriental medical clinic in western medical hospital, equip western medical care instrument in oriental medical hospital, improve oriental medical care instrument carry out a herb specialist system, balance the resonable medical care cost and effort for further study & research on oriental medicine to satisfy increasing need of oriental medicine.

• 동의신경정신과학회지
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• 제19권1호
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• pp.125-146
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• 2008

Objectives : The purpose of this study is to suggest for the following experimental study of dementia by reviewing recent oriental medicine journals that have been published since 2000. Methods: We have investigated various types of studies in relation to dementia through 90 articles that have been published from 2000 to 2007 in recent oriental medicine journals were registered Korea research foundation. Results and Conclusions : 1. Since 2000, 88 articles in relation to dementia have been published and almost of them are herbal medicine-centered studies. Also they show a tendency to increase every year. The journal of oriental neuropsychiatry carries the highest number of studies in relation to dementia. 2. According to the experimental paper, there are 30 cases of using herb simplexes, 48 cases of herb-combined prescription, and 10 cases of other ways. Especially 7 cases of using herb-combined prescription relation to Sasang constitution are all for the Taeumin. 3. There are 85 cases of Animal and cellular experimental, 60 cases of using pathologic model induced cytotoxic activity, a case of using L-NAME, 3 cases of 192 saporin, 4 cases of ibotenic acid, 10 cases of focal cerebral ischemia, 3 cases of alcohol-administered, and one case of natural degradation. 4. Moms water maze, Radial arm maze Passive avoidance learning model were using for examining learning and memory of model animal 5. We propose that following studies of dementia are to he investigated of the applied method of using siRNA with tranceduced gene, sample preparation by water-soaking, oriental medical diagnosis, standardization of differentiating symptom and herb simplexes, building the database by classified prescriptions, and experiment model which are based on precise examining mechanism with cell line as like mouse H19-7 hippocampus, rat HT22 hippocampus, astrocyte, microglia, using the model of animals at APP, PS1, BACE, CT99/PS1, APOE4, Tau, APP/PSI/Tau