• Journal of Korean Ophthalmic Optics Society
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• v.15 no.2
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• pp.123-130
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• 2010

Purpose: The study was conducted to compare the values of auto-refraction, manifest refraction and cycloplegic refraction in school-aged children. Methods: One hundred five myopic school children ranged from 6 to 14 years old (210 eyes, $10.28{\pm}1.59$ years old) were recruited and noncycloplegic auto-refraction (AR) and manifest refraction (MR) were conducted and then underwent cycloplegia and refractive status (CR) again with the auto-refractometer. Results: Refractive powers measured by AR, MR, and CR were highly correlated. However, spherical and cylindrical powers of the subjects measured by AR were measured higher negative power than in CR (p<0.001). From 210 eyes, the discrepancy rate in the spherical and cylindrical powers were 40 eyes (19%) and 19 eyes (9%) of the total subjects, respectively and the differences between noncycloplegic and cycloplegic refractions were higher with the spherical and cylindrical powers increasing. Conclusions: The use of the autorefractometer in children with negative spherical power without cycloplegia may overestimate the actual myopia that subjective refraction is the most important in prescription for the eyeglasses and regression equations would be used to prognose the cycloplegic refraction from the auto-refraction as the basic data for the subjective refraction.

• Journal of Life Science
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• v.21 no.8
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• pp.1142-1148
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• 2011

This study was conducted to investigate antioxidative and physiological activities of ethanol extracts concentration from Monascus-Fermented Chinese Yam (MFCY). The ethanol extracts from MFCY were measured to examine pigment, monacolin K content, total polyphenol content, DPPH radical scavenging activity and angiotensin converting enzyme inhibitory effects. In this study, the results show that Monascus sp. MK2, with Dioscorea batatas Dence. as the substrate, can produce pigments (red, orange, and yellow), monacolin K content, total polyphenol content and DPPH radical scavenging activity at 13.48 (red), 11.66 (orange), 12.77 (yellow), 462.78 (mg/kg), 658.8 (mg/kg) and 92.8% in EtOH extract, respectively. In addition, ACE inhibitory activity was shown to be 74.55% in EtOH extract. Therefore, it can be concluded that Dioscorea batatas Dence is the best fermentative substrate for Monascus species to produce secondary metabolites as biomedicinal substances.

• Journal of the Korean Society of Radiology
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• v.5 no.6
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• pp.409-413
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• 2011

An X-ray tube used an X-ray fluorescence analysis system has a low X-ray photon intensity which results in reducing measurement accuracy and increasing exposure time. These shortages can be overcame by using a monocapillary optics. A monocapillary optics was optimally designed for focusing the characteristic X-ray of tungsten (8.4 keV). The monocapillary optics can achieve a gain of 10 at the least. The monocapillary optics was fabricated by using puller and pyrex glass, raw material. In fabrication, a weigh of 45g and a temperature of $650^{\circ}$ was loaded. The total fabrication time was 460 minutes. The fabricated capillary had 87 mm in length and maximum diameter of 300 ${\mu}m$ and minimum diameter of 192 ${\mu}m$. When the fabricated monocapillary optics is applied to an X-ray fluorescence analysis system, the detection accuracy for soft elements, for example sulfur (S), will be improved.

• Journal of Korean Ophthalmic Optics Society
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• v.11 no.4
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• pp.329-335
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• 2006

The aim of this study was to evaluate the relation between Asthenopia of near lateral phoria and fusional reserve and also to provide fundamental clinical data. A total of 97 subjects, aged between 17 and 35 years old, who had no strabismus, an eye trouble or whole body disease, were examined nacked visual acuity, corrected visual acuity, corrected diopter, phoria, fusional reserve tests from October of 2005 to July of 2006. We excluded 8 subjects for the following reasons: if they had an amblyopia affecting binocular vision or inaccurate data. After these exclusions, 87 subjects remained. The results were as follow. According to interview results was that in near works, exophoria and esophoria with asthenopia was 59.6%, 64.7%, and 52.6% respectively. The subjects who have exophoria of $0-6{\Delta}$ in the range of normal state was 19.1%. The subjects who have exophoria of $7{\Delta}$ over in the range of abnormal state was 80.9%. The fusional reserve was in inverse proportion to phoria. The fusional reserve was twice over of phoria were 30.3%, and twice under were 69.7%. The asthenopia complain persons were 33.9% with the twice over fusional reserve of phoria. The asthenopia no complain persons were 66.1% with the twice under fusional reserve of phoria. In conclusion, our research has shown conclusively that there is a link between asthenopia of lateral phoria and fusional reserve and we also find that fusional reserve must be examined when we prescribe for a patient who has phoria.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.4
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• pp.519-526
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• 2015

Purpose: To evaluate the changes of OSI value according to tear-film instability measured serially by OQAS(Optical Quality Analysis System, Visiometrics, Spain) every seconds. The presented study analyzed the relationship of the OQAS parameter with the results of the tear-film break-up time, Schirmer test, and the McMonies score. Methods: 147 eyes of 82 subjects were randomly selected from university students (age: $21.51{\pm}3.97$, male 45, female 37). Subjects were measured tear-film break-up time, Schirmer test, McMonies score and once every second for 15 seconds after blinking by continuous measurements from OQAS system. Results: The normal eye groups presented OSI values of $2.13{\pm}1.16$ while the dry eye groups had OSI values of $3.76{\pm}1.42$. Therefore, a significant difference between the normal eye group and dry eye group was discovered (p<0.05). In addition, the OSI value of all subjects increased over time. The OSI value, which was measured every second after blinking occurred, significantly increased between 6 seconds and 7 seconds after the start of the measurement (p<0.05). OSI cut off of 30% (sec.) showed a greater correlation; TBUT (r = 0.855, p = 0.000), McMonies test (r = -0.351, p = 0.003), Schirmer (r = 0.316, p = 0.012). Conclusions: Continuous measurement of OQAS showed a high correlation with the value of the existing dry eye tests. Therefore, Analysis of OSI values by utilization of OQAS could be useful in objectively evaluation of tear film in patients.

• Korean Journal of Microbiology
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• v.48 no.1
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• pp.29-36
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• 2012

This study was conducted to investigate antioxidative and physiological activities of two stage fermented Chinese Yam (TSFCY) by Monascus sp. MK2 and Lactobacillus brevis HLJ59. The extracts from TSFCY were measured to examine pigments, monacolin K contents, total polyphenol and flavonoid contents, DPPH radical scavenging activity, reducing power, ACE inhibitory activity and GABA contents. In this study, the results show that Monascus sp. MK2 and Lactobacillus brevis HLJ59, with Dioscorea batatas Dence. As the substrate can produce pigments (yellow, orange and red), monacolin K contents, total polyphenol and flavonoid contents, DPPH radical scavenging activity, reducing power, ACE inhibitory activity, and GABA contents at 14.03 (yellow), 13.88 (orange), 15.71 (red), 487.9 (MK, mg/kg), 723.8 (TP, mg/kg), 326.4 (TF, mg/kg), 81.7 (DPPH, %), and 1.5 (RP, O.D), respectively. In addition, the showed ACE inhibitory activity and GABA contents was 86.9% and 977.4 mg/kg in EtOH extract, respectively.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.3
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• pp.285-291
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• 2012

Purpose: This study was conducted to research any effect on visual function related to accommodation by VDT work. Methods: The refraction power, accommodative lag, accommodative facility, relative accommodation, amplitude of accommodation and blink rate were measured before and after VDT work for 2 hours on 48 university students (16 males and 32 females), without abnormal accommodative function and systemic and ocular disease, who had never undergone corrective eye surgery. All examinations were performed with distant refraction, and a survey was conducted on the items related to subjective symptoms of VDT syndrome. Results: After 2 hours of VDT work, refractive power increased by 0.23 D, the amount of change in accommodative lag were $0.17{\pm}0.42D$ in the right eye and $0.23{\pm}0.47D$ in the left eye (t=2.26, p=0.03). There were statistically significant differences. Both the accommodative facility and relative accommodation and amplitude of accommodation were decreased after work. However, blink rate were increased. After VDT work, 33.4% of the subjects showed subjective symptoms of asthenopia and 33.3% of them showed shoulder pain. Conclusions: As a result, the accommodative lag increased in response to the two hours of VDT work, and overall accommodative functions were decreased. In addition, as symptoms of providing visual strain, asthenopia showed the most prominent subjective symptoms.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.1
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• pp.17-22
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• 2014

Purpose: We aimed to evaluate reliability of eye exam for visual acuity as a function of distance. Methods: There were 39 patients (78 eyes) who had visual acuity 1.0 or more at 5 meters. We measured refractive power of patients at each distances, 5 meters, 4 meters and 3 meters. Automatic chart (LCD-700, Hyeseong Optic. Co., Korea) used for visual acuity, skiascope (Beta 200, Heine, Germany) and auto refractometer (RK-5, Canon, Japan) used as for objective refraction. Accommodation was examined by minus lens addition methods, and Accommodative lag was examined by grid chart for reading distance. Results: Being compared to 3 meter test, Amount of corrected spherical refractive power decreased by $0.10{\pm}0.38$ D, astigmatism decreased by $0.05{\pm}0.10$ D, and axis of astigmatism rotated toward to temporal by $2.64{\pm}18.75$ degrees for right eyes, by $11.43{\pm}48.55$ degrees for left eyes in case of 5 meter test. Changes of corrected refraction and astigmatism were slightly correlated (r=-0.31, r=-0.29). Conclusions: Because corrected refraction power and amount of astigmatism decreased and axis of astigmatism tends to turn the temporal direction according to exam distance, examination distance of visual acuity should improved as to 5 meters.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.1
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• pp.99-104
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• 2014

Purpose: This study was to investigate the functional improvement in peripheral vision following eccentric viewing training. Methods: 14 subjects with normal vision took a part with their right eye, peripheral retinal which is $20^{\circ}$ lateral area from the fovea was examined for contrast sensitivity(CS). Eccentric viewing training was performed for 21days with an hour image viewing and examination was repeated. Results: The critical durations for 0.7 cpd were increased 2.67(467 ms) for pre-eccentric viewing training to 2.79(616 ms) for post-eccentric viewing training (p>0.05). The critical durations for 3.0 cpd were also increased 2.53(341 ms) for pre-eccentric viewing training to 3.04(1102 ms) for post-eccentric viewing training (p>0.05). Conclusions: It is recommended to use higher spatial frequency with higher CS for eccentric viewing training and to train more frequently for a short time. Moreover, the study on Korean standardizing of the visual rehabilitation for low vision based on the etiology is sorely required.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.2
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• pp.201-210
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• 2015

Purpose: In order to aggregate effect of the improvement of binocular vision function by vision therapy, total mean effect size, mean effect size by dependent variables, and effect size by characteristics of the subjects and characteristics of treatment were analyzed by meta-analysis. Methods: We analyzed data from 14 Korean National primary studies, which reported effects of vision therapy programs, using meta-analysis. Results: The effect size of total mean was 1.207, which showed high effect. The mean effect size according to the subcategory of the binocular dysfunctions was the highest for vergence dysfunctions group (2.989), followed by accommodative dysfunctions group (0.868) and group with both vergence dysfunctions and accommodative dysfunctions (0.692). The effect size according to the characteristics of the subjects was the highest in the vision therapy conducted in the binocular dysfunctions group (2.509) that had no other dysfunctions. The mean effect size according to the number of programs was the highest (2.310) for 7 times a week. Vision therapy for improving the binocular functions was the most effective (2.019) in 8 weeks later from vision therapy start. Conclusions: It can prove that the therapy for the improvement of binocular vision function is effective through that each result of the vision therapy effect is converted to mean effect size, and being objectifying the mean effect size.