• 대한전기학회:학술대회논문집
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• 대한전기학회 1999년도 하계학술대회 논문집 G
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• pp.2866-2868
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• 1999

S/W 시스템을 개발하여 테스트한 후 발행시기를 결정함에 있어서 그동안의 비용-신뢰도를 동시에 고려하여 최적발행시기를 결정하고자 하는 연구결과가 얼마나 현실적으로 합리적이고 타당한가를 고찰하고자 한다. 연구방법으로서는 일반적인 비용-신뢰도 최적발행에 대한 기존의 관련논문을 중심으로 제시된 연구방법들에 대해서 연구해보고. 특히 그 최적발행정책의 한계성에 대해서 중점적으로 연구하고자 한다.

• 약학회지
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• 제42권2호
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• pp.187-195
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• 1998

In order to ameliorate disadvantages of buccal ointments and mucoadhesive tablets used for the treatment of aphthosis, a thin mucoadhesive patch containing triamcinolone acetoni de was designed and evaluated for the pharmaceutical properties. The adhesive gel layer consisting of Noveon AA-1, hydroxypropylcellulose-M and ethylcellulose N 100, and the protective gel layer of ethylcellulose N 100, Eudragit RSPO and castor oil have been formulated and various properties such as viscosity of drug gel layer, thickness, in vitro adhesion time, adhesive strength, surface pH, content uniformity and drug release are tested. The mean viscosity of drug-containing gel layer was found to increase with increasing amount of Noveon OAA-1 or hydroxypropylcellulose-M. The optimum formulation showed the thickness of 171 ${\mu}$m, surface pH of 4.6, in vitro adhesion time of 8 hours and adhesive strength of 272.7g/sheet. The drug content of each patch was relatively homogeneous with the value of 273${\pm}$6.77g. Drug release study showed that compared to mucoadhesive tablet, the patch showed a faster drug release. Drug release was delayed by hydroxypropylcellulose-M, but not by ethylcellulose N 100. The patches prepared were nonirritant and the muco adhesion was better than the commercial product (AftachR) on the market. Based on these results, this mucoadhesive patch is expected to be an effective dosage form for the treatment of aphthosis.

• 약학회지
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• 제33권3호
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• pp.191-202
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• 1989

Indomethacin, a non-steroidal antiinflammatory drug inducing gastric irritation, was microencapsulated using pectin-gelatin complex coacervation method. Optimum conditions for microencapsulation and dissolution characteristics of the microcapsules were studied. The optimum pH and pectin-gelatin ratio for microencapsulation were 3.8 and 1:2 respectively. As concentration of colloid solution increased, wall thickness of microcapsules were increased. The dissolution rate of Indomethacin-pectin-gelatin microcapsules prepared by 1.5% and 2% colloid solution were similar but slower than that of Indomethacin-pectin-gelatin microcapsules prepared by 1% colloid solution. The 50% release time ($T_{50%}$) of Indomethacin-pectin-gelatin microcapsules prepared by 1%, 1.5% and 2% colloid solutions were 3 min, 5 min, and 6 min respectively while that of Indomethacin powder was 50 min.

• Journal of Information Technology Applications and Management
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• 제13권4호
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• pp.1-12
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• 2006

Many software reliability growth models(SRGM) have been proposed since the software reliability issue was raised in 1972. The technology to estimate and grow the reliability of developing S/W to target value during testing phase were developed using them. Most of these propositions assumed the S/W debugging testing efforts be constant or even did not consider them. A few papers were presented as the software reliability evaluation considering the testing effort was important afterwards. The testing effort forms which have been presented by this kind of papers were exponential, Rayleigh, Weibull, or logistic functions, and one of these 4 types was used as a testing effort function depending on the S/W developing circumstances. I propose the methology to evaluate the SRGM using least square estimator and maximum likelihood estimator for those 4 functions, and then examine parameters applying actual data adopted from real field test of developing S/W.

• 한국환경과학회지
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• 제14권9호
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• pp.861-871
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• 2005

This study was carried out to get more operational characteristics of Anoxic(anaerobic)-Oxic-Anoxic-Oxic $(AO)_2$ sequencing batch biofilm reactors (SBBRs) at the low TOC concentration, The operating time in anoxic (anaerobic) time to oxic time was I : I. Experiments were conducted to find the effects of the aeration time distribution on the organic matters and nutrients removal. Three lab-scale reactors were fed with synthetic wastewater based on glucose as carbon source. During studies, the operation mode was fixed. The first aeration time to the second aeration time in SBBR-I was 2 : 3, and those in SBBR-2 and SBBR-3 were I : 4 and 3 : 2, respectively. The organic removal efficiency didn't show large difference among three reactors of different aeration time distribution. However, from these study results, the optimum aeration time distribution in the first and the second aeration time for biological nutrient removal was shown as 3 : 2. The release of phosphorus was inhibited at the second non-aeration period because of the low TOC concentration and the nitrate produced by the nitrification at the first aeration period.

• 한국자동차공학회논문집
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• 제12권6호
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• pp.60-65
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• 2004

Numerical simulations and experiments have been carried out to investigate the effect of fuel injection nozzles on the combustion and NOx formation processes in a medium-speed marine diesel engine. Spray visualization experiment was performed in the constant-volume high-pressure chamber to verify the numerical results on the spray characteristics such as spray angle and spray tip penetration. Time-resolved spray behaviors were captured by high-speed digital camera and analyzed to extract the information on the spray parameters. Spray and combustion phenomena were examined numerically using FIRE code. Wave breakup and Zeldovich models were adopted to describe the atomization characteristics and NOx formation processes. Numerical results were verified with experimental data such as cylinder pressure, heat release rate and NOx emission. Finally, the effects of fuel injection nozzles on the engine performance were investigated numerically to find the optimum nozzle parameters such as fuel injection angle, nozzle hole diameter and number of nozzle holes. From this study, the optimum fuel injection nozzle (nozzle hole diameter, 0.32 mm, number of nozzle holes, 8 and fuel injection angle, $148^{\circ}$) was selected to reduce both the fuel consumption and NOx emission. The reason for this selection could be explained from the highest fuel-air mixing in the early phase of injection due to the longest spray tip penetration and the highest heat release rate after $19^{\circ}$ ATDC due to the increased injection duration.

• Food Science and Biotechnology
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• 제17권2호
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• pp.408-412
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• 2008

Determining the elution of water-soluble substances from herbal teas is an important factor in their efficient use in terms of taste, perfume, and content of health-related components. The antioxidant activity and content of catechins in commercial Chrysanthemum indicum (gamguk) teas were determined for optimum elution conditions. The water extract of gamguk teas did not differ significantly in yield compared to methanol extracts and showed stronger antioxidant activity. Catechin contents in gamguk teas were 8-18% of the extracts when individual peaks in high-performance liquid chromatography analysis were compared to standard catechin peaks. Gamguk teas exhibited faster release of antioxidants, and the antioxidant activity was positively correlated with the thermal treatments. Gukhwacha (GC) was the best tea for rapid release (30 sec) of antioxidants with the $50^{\circ}C$ treatment, whereas antioxidants in other teas were relatively slower released.

• 대한산업공학회지
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• 제25권1호
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• pp.47-55
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• 1999

This paper develops an efficient heuristic algorithm for scheduling workforce level that can accommodate all the requested maintenance jobs. Each job has its own release and due dates as well as man-day requirement, and must be scheduled in a non-interrupted time interval, namely, without preemption. Duration of each job is not fixed, but to be determined within given specific range. The objective is to minimize workforce level to complete all the requested maintenance jobs. We show that the problem can be seen as a variant of the two-dimensional bin-packing problem with some additional constraints. A non-linear mixed integer programming model for the problem is developed, and an efficient heuristic algorithm based on bin-packing algorithms is proposed. In order to evaluate goodness of the solution obtained from the proposed algorithm, a scheme for getting a good lower bound for the optimum solution is presented and analyzed. The computational experiment shows that the proposed algorithm performs quite satisfactorily.

• 한국작물학회지
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• 제37권6호
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• pp.499-505
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• 1992

본 시험은 완효성비료를 이용한 전량기비시비방법을 개선하고자 식양토(덕평통)와 사양토(강서통)에서 완효성비료인 조선완효성비료와 Meister 15를 이용하여 시비방법에 따른 완효성비료의 시용효과를 검토한 결과는 다음과 같다. 1. 공시토양별 암모니아태 질소의 용출량은 담수 4일째 사양토에서 95ppm, 식양토에서 60ppm 이었다. 2. 벼 잎색도는 조선완효성비료가 Meister 15보다 낮았고, 시비방법간에는 측조시비구보다 전층시비구에서 높았다. 3. 질소 효율은 Meister 15 > 관행 > 조선완효성비료의 순으로 높았고, 시비방법간에는 차이가 적었다. 4. 단립면적당 경수는 조선완효성비료는 측조시비구가 전층시비구보다 많았고, Meister 15는 전층시비구가 측조시비구보다 많았으며, 간장은 Meister 15 > 관행 > 조선 완효성비료의 순으로 길었고, 시비 방법간에는 전층시비구가 측조시비구보다 길었다. 등숙율은 완효성시비가 관행보다 높았고, 시비방법간에는 전층시비구가 측조시비구보다 낮았다. 5. 수량은 식양토에서 비료간 수량차이가 컸으나, 시비방법간에는 수량차이가 적었고, 사양토에서는 비료간, 시비방법간에 수량차이가 적었다. 6. 이상의 결과에서 Meister 15와 같은 완효성비료는 전층시비법으로 시용하여도 좋을 것으로 판단되었다.

• 한국수산과학회지
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• 제32권4호
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• pp.452-457
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• 1999

적조 현상이 나타난 남해안 연안의 뻘로부터 Cochlodinium polykrikoides에 대한 살조능을 가지는 살조 세균 KY1을 분리하였다. 분리된 살조 세균 KY1이 살조능을 나타내는 최적 조건은 $30^{\circ}C$, 염농도 $3\%$, pH 5 이상의 중성으로 확인되었으며, 약 8 시간의 배양에서 대수 증식의 최대 성장률을 보였으며, 이후 사멸기 까지 배양 시간 24 시간 경과 후부터 높은 살조능을 나타내었다. 살조능은 대수증식기에서 정지기로 넘어갈 때, 큰 폭으로 증가하였다. 그리고, 사멸기에서는 최대 $100\%$에 달하는 살조능을 나타내었다. 이는 살조 세균이 분해되면서 균체내에 존재하는 살조물질을 분비하는 것으로 간주된다. 또한 배양 상등액의 양을 증가시켰을 때, 1 시간 이내에 $40{\mu}{\ell}$/ml의 농도에서 $100\%$의 살조능을 볼 수 있었다. $Zn^{2+}$의 첨가로 살조능의 현저한 증가를 확인 할 수 있었으며, 이로부터 살조물질은 C. polykrikoides의 세포벽 성분인 mannan을 분해하는 $\alpha$-mannosidase일 가능성을 보였다.